Mutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with grade 3 endometrioid endometrial carcinomas.

scientific article published on 31 December 2015

Mutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with grade 3 endometrioid endometrial carcinomas. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YGYNO.2015.12.031
P698PubMed publication ID26748215

P50authorSze Huey TanQ60061128
P2093author name stringWanjin Hong
Eva Loh
Joanne Ngeow
Sung Hock Chew
Chik Hong Kuick
Sorsiah Mansor
Sock Hoai Chan
Adele Wong
Jill M Tham
Sudhanshi Jain
Wai Loong Wong
Shao Tzu Li
Nadkarni N Vikas
P2860cites workGlobal cancer statisticsQ22241238
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomasQ24617520
Genetic structure of the Han Chinese population revealed by genome-wide SNP variationQ24644546
Replicative DNA polymerase mutations in cancerQ26825747
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing dataQ27860742
POLE Proofreading Mutations Elicit an Antitumor Immune Response in Endometrial CancerQ28260529
Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancersQ28286394
DNA polymerase ε and δ exonuclease domain mutations in endometrial cancerQ28287769
Integrated genomic characterization of endometrial carcinomaQ28289962
DNA replication fidelity and cancerQ28295863
Genetic relationship of populations in ChinaQ28776512
Assessment of computational methods for predicting the effects of missense mutations in human cancersQ34790059
Prognostic significance of POLE proofreading mutations in endometrial cancer.Q34994583
Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients.Q35748591
Endometrial carcinomas with ambiguous features.Q37838982
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancerQ39001975
PIK3CA missense mutation is associated with unfavorable outcome in grade 3 endometrioid carcinoma but not in serous endometrial carcinoma.Q44448363
Comparative outcomes assessment of uterine grade 3 endometrioid, serous, and clear cell carcinomas.Q53114197
Polymerase proofreading-associated polyposis: a new, dominantly inherited syndrome of hereditary colorectal cancer predisposition.Q54295450
POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium.Q54351302
Pathologic features of endometrial carcinoma associated with HNPCCQ60167348
Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27Q78444965
Routinely assessed morphological features correlate with microsatellite instability status in endometrial cancerQ81469179
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)113-120
P577publication date2015-12-31
P1433published inGynecologic OncologyQ5625182
P1476titleMutation spectrum of POLE and POLD1 mutations in South East Asian women presenting with grade 3 endometrioid endometrial carcinomas
P478volume141

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cites work (P2860)
Q91045434Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population
Q90266865Detection of POLE Subtypes in High-Grade Endometrioid Carcinoma by BaseScope-ISH Assay
Q57788834Elevated expression of POLD1 is associated with poor prognosis in breast cancer
Q49911660Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae
Q92187270Germline POLE and POLD1 proofreading domain mutations in endometrial carcinoma from Middle Eastern region
Q33755092Incomplete Segregation of MSH6 Frameshift Variants with Phenotype of Lynch Syndrome
Q91911974Interpretation of somatic POLE mutations in endometrial carcinoma
Q46364204Molecular-based classification algorithm for endometrial carcinoma categorizes ovarian endometrioid carcinoma into prognostically significant groups
Q38709274Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polymerase δ mutation in human cells
Q38870074POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies
Q92009964POLE proofreading defects: Contributions to mutagenesis and cancer
Q64114943Phenotype of POLE-mutated endometrial cancer
Q39421725Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy

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