Anticonvulsant drugs. An update

scientific article published on April 1984

Anticonvulsant drugs. An update is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1035551114
P356DOI10.2165/00003495-198427040-00003
P8608Fatcat IDrelease_65lmytm74zea5paw3oq3qrgje4
P698PubMed publication ID6327221

P2093author name stringM J Eadie
P2860cites workSequelae after the intravenous injection of three benzodiazepines--diazepam, lorazepam, and flunitrazepamQ28316862
Stupor Following Administration of Valproic Acid to Patients Receiving Other Antiepileptic DrugsQ28319205
Diphenylhydantoin Sensitivity. A Syndrome Resembling Infectious Mononucleosis with a Morbilliform Rash and Cholestatic HepatitisQ28319528
Tremor due to sodium valproateQ28325069
The fetal trimethadione syndrome: report of an additional family and further delineation of this syndromeQ28325493
Intravenous phenytoin: Clinical and pharmacokinetic aspectsQ28330095
Diphenylhydantoin-induced acute renal failureQ28331432
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neurolepticsQ28335688
Serum clonazepam concentrations in children with absence seizuresQ28336526
Digoxin-phenytoin interactionQ28365258
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbituratesQ28366176
Sodium valproate, platelet dysfunction, and bleedingQ33481528
Lymphadenopathy induced by anticonvulsant drugs and mimicking clinically pathologically malignant lymphomasQ33969972
Pharmacokinetics and side-effects of clonazepam and its 7- amino-metabolite in manQ34151795
Drug Interactions During Anticonvulsant Therapy in Childhood: Diphenylhydantoin, Primidone, Phenobarbitone, Clonazepam, Nitrazepam, Carbamazepin and DipropylacetateQ34170346
Sulthiame (Ospolot) as inhibitor of diphenylhydatoin metabolism.Q34208762
Human pharmacokinetics of nitrazepam: Effect of age and diseasesQ34212765
Effects of Phenytoin on Serum y-Glutamyl Transpeptidase ActivityQ72475336
The effect of phenobarbital on plasma diphenylhydantoin level and metabolism in man and in rat liver microsomesQ72505905
EpilepsyQ72540124
Interactions between prim done, carbamazepine, and nicotinamideQ72765756
The role of folate deficiency in the development of peripheral neuropathy caused by anticonvulsantsQ72872715
The interaction of barbiturates with serum albumin and its possible relation to their disposition and pharmacological actionsQ73536304
Phenobarbital: studies of elimination, accumulation, tolerance, and dosage schedulesQ73564415
Diphenylhydantoin sensitivity; report of fatal case with hepatitis and exfoliative dermatitisQ73938395
Quantitative studies of the metabolic fate of mephobarbital (N-methyl phenobarbital)Q73963976
The metabolic hydroxylation of phenobarbitalQ73970865
Metabolic conversion of primidone (mysoline) to phenobarbitalQ74349568
The metabolic conversion of 5, 5-diphenyl hydantoin to 5-(p-hydroxyphenyl)-5-phenyl hydantoinQ74594017
Effects of diphenylhydantoin on synaptic transmission in cat spinal cord and stellate ganglionQ74660352
[ON THE PHARMACOLOGY OF MOGADON, A HYPNOTIC WITH AN UNUSUAL ACTION MECHANISM]Q77230595
PHENOBARBITAL-INDUCED INCREASE IN 6-BETA-HYDROXYCORTISOL EXCRETION: CLUE TO ITS SIGNIFICANCE IN HUMAN URINEQ78248238
DRUG INTERACTIONS IN MAN. I. LOWERING EFFECT OF PHENOBARBITAL ON PLASMA LEVELS OF BISHYDROXYCOUMARIN (DICUMAROL) AND DIPHENYLHYDANTOIN (DILANTIN)Q78443509
Neuropharmacology and neurochemistry of anticonvulsant drugsQ78619793
Exfoliative dermatitis and hepatitis due to phenobarbitalQ80680980
Influence of folic acid on blood-phenytoin levelsQ93694688
Acute primidone intoxicationQ34219145
Cerebrospinal-fluid concentrations of nitrazepam in man.Q34239485
Transfer of nitrazepam across the human placentaQ34243003
Rectal drug administration: clinical pharmacokinetic considerationsQ34246983
Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokineticsQ34270748
Plasma levels of primidone and its metabolite phenobarbital: effect of age and associated therapyQ34271569
Antiepileptic Drugs: Biotransformation, Metabolism, and Serum Half-LifeQ34359667
Salivary concentrations and plasma protein binding of carbamazepine and carbamazepine 10,11-epoxide in epileptic patientsQ34448908
Valproic acid and diazepam interaction in vivoQ34450028
Plasma protein binding of phenytoin in the aged: in vivo studiesQ34450124
Phenytoin dose adjustment in epileptic patientsQ34451359
Changes in drug metabolism with increasing age: 2. phenytoin clearance and protein bindingQ34451491
The effects of age and liver disease on the disposition and elimination of diazepam in adult manQ34473755
Controlled trial of frusemide as an antiepileptic drug in focal epilepsyQ34515240
Effect of phenytoin therapy on thyroid functionQ34515422
Factors influencing plasma phenobarbitone levels in epileptic patientsQ34516004
The levels of anticonvulsants in breast milkQ34517631
Effects of subjects' sex, and intake of tobacco, alcohol and oral contraceptives on plasma phenytoin levelsQ34517775
Reduction of oral bioavailability of lignocaine by induction of first pass metabolism in epileptic patientsQ34517822
Modification of phenytoin clearance by valproic acid in normal subjectsQ34518500
Diazepam and N-desmethyldiazepam concentrations in saliva, plasma and CSFQ34518792
Comparison of plasma and saliva levels of diazepamQ34518984
Interactions between anticonvulsantsQ34561260
Phenytoin-theophylline interactionQ34715451
Pancreatitis during sodium valproate treatmentQ35117150
Interactions with Antiepileptic DrugsQ36493244
Chronic Antiepileptic Toxicity: A ReviewQ36522161
Pathophysiology behind anticonvulsant osteomalaciaQ36614874
Treatment of epilepsy with clonazepam and its effect on other anticonvulsantsQ37053391
The distribution of plasma phenytoin levels in epileptic patientsQ37070680
The Teratogenic Risk of Antiepileptic DrugsQ38094480
Acute Toxicity of Antiepileptic DrugsQ38094502
Metabolic fate of phenobarbital. A quantitative study of p-hydroxyphenobarbital elimination in manQ39136268
Pharmacokinetics of Diazepam in Dogs, Mice and HumansQ52739703
Acute diphenylhydantoin intoxication following halothane anesthesia.Q52741995
Plasma disappearance of transplacentally transferred diphenylhydantoin in the newborn studied by mass fragmentography.Q53864786
Increased Rate of Clearance of Drugs from the Circulation of Alcoholics*Q54004788
Effect of methylphenidate on plasma anticonvulsant levelsQ54033546
Diphenylhydantoin intoxication attendant to slow inactivation of isoniazid.Q54054255
Intramuscular administration of diphenylhydantoin. Histologic follow-up studies.Q54065624
Diphenylhydantoin and an insulin-secreting islet adenoma.Q54260776
Folate therapy in epilepsy. A controlled study.Q54293478
Effect of diphenylhydantoin on cortisol kinetics in humansQ54306410
Clonazepam--a clinical study of its effectiveness as an anticonvulsantQ54312115
Interaction between Doxycycline and BarbituratesQ54384492
Low plasma-bilirubin in epileptics on phenobarbitone.Q54432717
Effect of diphenylhydantoin on the metabolism of dicoumarol in man.Q54488007
Osteomalacia with Long-term Anticonvulsant Therapy in EpilepsyQ54732571
Altered Calcium Metabolism in Epileptic Children on AnticonvulsantsQ55174462
Hyponatraemia during carbamazepine treatment.Q55410979
Nitrazepam in myoclonic epilepsiesQ57605674
Letter: Amines, anticonvulsants, and epilepsyQ66701303
Plasma protein binding of carbamazepineQ66918773
Flow-Dependent Salivary Primidone Levels in Epileptic ChildrenQ66923351
Decreased serum 24,25-dihydroxy vitamin D concentrations in children receiving chronic anticonvulsant therapyQ66956225
Anticonvulsant Level in Saliva, Serum, and Cerebrospinal FluidQ66956563
Plasma anticonvulsant concentrations during pregnancyQ67010508
Plasma Drug Level Monitoring in PregnancyQ67041229
The pharmacokinetics of carbamazepineQ67052582
The clinical pharmacokinetics of phenytoinQ67053866
Interaction between carbamazepine and propoxyphene in manQ67062825
Inhibition of drug metabolism by chloramphenicolQ67211676
Trimethadione and human teratogenesisQ67262200
[The effect of hydantoin and succinimide on vitamin B 6 metabolism]Q67267329
Kinetics of carbamazepine and carbamazepine-epoxide, determined by use of plasma and salivaQ67274955
Effect of Antiepileptic Drugs on Serum and Salivary IgAQ67332082
Phenytoin and phenobarbital concentrations in saliva and plasma measured by radioimmunoassayQ67353832
The bioavailability of carbamazepineQ67369698
Diphenylhydantoin, Phenobarbital, and Primidone in Saliva, Plasma, and Cerebrospinal FluidQ67380294
Paradoxical Intoxication,:A Complication of Anticonvulsant AdministrationQ67380298
Distribution and elimination kinetics of carbamazepine in manQ67396517
Plasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple dosesQ67396551
Binding of amobarbital, pentobarbital and diphenylhydantoin to blood cells and plasma proteins in healthy volunteers and uraemic patientsQ67396592
Drug-Induced IgA Deficiency in Epileptic PatientsQ67442398
Phenytoin: Pharmacokinetics and bioavailabilityQ67443828
Pharmacokinetic Model to Describe Self‐Induced Decreases in Steady‐State Concentrations of CarbamazepineQ67445131
A comparison of the absorption of phenobarbitone given via the oral and the intramuscular routeQ67459965
Thickening of the heel-pad associated with long-term Dilantin therapyQ67510234
Isoniazid as an inhibitor of primidone metabolismQ67514754
Studies on the concentrations of chloramphenicol in the serum and cerebrospinal fluid of neonates, infants, and small children. Reciprocal reactions between chloramphenicol, penicillin and phenobarbitoneQ67541138
Excretion of Valproic Acid into Semen of Rabbits and ManQ40991325
Effect of Anticonvulsants on Spiking Activity Induced by Cortical Freezing in CatsQ41004943
Valproic Acid Binding to Human Serum Albumin and Determination of Free Fraction in the Presence of Anticonvulsants and Free Fatty AcidsQ41004959
Acute Hepatic Failure Associated with the Use of Sodium ValproateQ41024278
The effect of diphenylhydantoin, diazepam and clonazepam on the activity of Purkinje cells in the rat cerebellumQ41063601
Reye-like syndrome associated with valproic acid therapyQ41098265
Carbamazepine intoxication caused by interaction with isoniazid.Q41112491
Effects of antiepileptic drugs on thalamocortical excitabilityQ41342850
Sodium valproate in the treatment of intractable seizure disorders: A clinical and electroencephalographic studyQ41358363
Factors influencing plasma concentrations of ethosuximideQ41443333
Antiepileptic drugs: metabolism in pregnancyQ41443340
Epilepsy Among Parents of Children with Facial CleftsQ41445113
Phosphorylation of the membrane-bound acetylcholine receptor: Inhibition by diphenylhydantoinQ41477940
A comparative study of the protein binding of anticonvulsant drugs in serum of dog and manQ41506601
Valproate-induced hepatic injury: analyses of 23 fatal casesQ41602314
Effect of Calcium and Antacids on Phenytoin BioavailabilityQ41667139
Intravenous phenobarbital therapy in barbiturate and other hypnosedative withdrawal reactions: A kinetic approachQ41677095
Pharmacokinetics of Phenobarbital Following Single and Repeated DosesQ41740591
Phenytoin cumulation kineticsQ41854366
Diazepam absorption: effect of antacids and foodQ41888961
The treatment of childhood epilepsy with sodium valproateQ41896934
Pharmacokinetics of valproic acid in young and elderly subjectsQ42089592
Do anticonvulsants have a teratogenic effect?Q42232913
Management of epilepsy with diphenylhydantoin sodium. Dosage regulation for problem patientsQ42239557
Hyperglycemic, nonketotic coma following administration of Dilantin (Diphenylhydantoin).Q42239695
Methylphenidate Interaction With Both Anticonvulsants and Ethyl BiscoumacetateQ42239819
Phenytoin (Dilantin) intoxicationQ42240232
Asterixis associated with sodium valproateQ42257339
Stuporous episodes during treatment with sodium valproate: report of seven casesQ42258113
Pharmacokinetics of di-n-propylacetate in epileptic patientsQ42596442
Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and ratQ42596456
Pharmacokinetics of the anticonvulsant drug clonazepam evaluated from single oral and intravenous doses and by repeated oral administrationQ42597665
Interaction of phenytoin with chlorpheniramine [letter]Q43241793
Steady-state plasma nortriptyline concentrations in epileptic patients [letter]Q43241905
Interaction between phenytoin and imipramineQ43253551
Quantitation of phenobarbital and its main metabolites in human urineQ43455187
Reduced CSF IgG in patients treated with phenytoin (diphenylhydantoin)Q43628262
Morphine and phenytoin binding to plasma proteins in renal and hepatic failureQ43713096
Idiosyncratic reactions to the antiepileptic drugsQ43719718
Ceruloplasmin rise and PBI fall in serum due to diphenylhydantoinQ43800491
Effect of diphenylhydantoin on the metabolism of dexamethasoneQ43820962
Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepineQ43846197
Absorption and distribution of antiepileptic drugsQ43869869
Diphenylhydantoin concentrations in salivaQ43972399
Inhibition of diphenylhydantoin metabolism by chloramphenicolQ43983201
Drug interactions: effect of methylphenidate on the disposition of diphenylhydantoin in man.Q44001501
Effect of antiepileptic drugs on the elimination of various tetracycline derivativesQ44288410
Bioavailability and single-dose pharmacokinetics of intramuscular phenytoinQ44306123
Plasma protein binding, plasma concentrations, and effects of diphenylhydantoin in man.Q44354325
Elevation of diphenylhydantoin and primidone serum concentration by addition of dipropylacetate, a new anticonvulsant drugQ44416330
The efficacy of carbamazepine combinations in epilepsyQ44498076
Interaction of chloramphenicol with phenytoin and phenobarbital. Case reportQ44653033
Pharmacokinetics of single and multiple doses of phenytoin in manQ44673846
Preliminary observations on the pharmacokinetics of methylphenobarbitoneQ45059575
Metabolism of ethosuximideQ45119512
Ethosuximide in the treatment of absence (peptit mal) seizuresQ45215486
Incidence of diphenylhydantoin gingival hyperplasiaQ45251373
Anticonvulsant osteomalacia determined by quantitative analysis of bone changes. Population study and possible risk factorsQ46281005
Use of phenytoin serum levels in a case of status epilepticusQ46337990
The rate of decline of diphenylhydantoin in human plasmaQ46365064
Effect of phenytoin on meperidine clearance and normeperidine formationQ70971402
Absorption and elimination of ethosuximide in childrenQ70990035
Cimetidine-phenytoin interaction: effect on serum phenytoin concentration and antipyrine testQ71040517
A clinical study of serum primidone levelsQ71045931
Interactions between digitoxin and other drugs in vitro and in vivoQ71065191
The clearance of anticonvulsant drugs in pregnancyQ71120024
Phenytoin intoxication during treatment with antabuse (Disulfiram)Q71193658
Effect of calcium and antacids on phenytoin bioavailabilityQ71232120
Effect of dose on phenytoin absorptionQ71295491
Kinetics of a carbamazepine-ethosuximide interactionQ71395561
Concentrations and kinetics of carbamazepine in whole saliva, parotid saliva, serum ultrafiltrate, and serumQ71395569
Practical and theoretical aspects of phenytoin administration. I. Relationship between dose and plasma concentrationQ71397081
Phenobarbital--valporic acid interactionQ71494424
Pancreatitis associated with valproic acid therapy for epilepsyQ71496427
Serum of concentrations of immunoglobulins in patients with epilepsy treated with carbamazepineQ71502905
Primidone kinetics: effects of concurrent drugs and duration of therapyQ71509210
Diphenylhydantoin and primidone in tearsQ71511172
Valproic acid dosage and plasma protein binding and clearanceQ71514895
Interaction between phenytoin and valproic acid: plasma protein binding and metabolic effectsQ71523457
Disappearance of phenobarbital and diphenylhydantoin from serum of childrenQ71533423
Mechanism of valproate-phenobarbital interaction in epileptic patientsQ71537576
Monotherapy or polytherapy for epilepsy?Q71537832
Protein binding of valproic acid in the presence of elevated free fatty acids in patient and normal human serumQ71537837
Concentration of metabolites of valproic acid in plasma of epileptic patientsQ71537861
Human brain, plasma, and cerebrospinal fluid concentration of sodium valproate after 72 hours of therapyQ71543340
Anticonvulsant activity of metabolites of valproic acidQ71545222
Valproic acid disposition in epileptic patients during combined antiepileptic maintenance therapyQ71552394
Hyperammonemia with valproic acid therapyQ71558786
Reduction of steady-state valproate levels by other antiepileptic drugsQ71562582
Outbreak of Anticonvulsant Intoxication in an Australian CityQ71582815
Interaction between valproic acid and aspirin in epileptic children: serum protein binding and metabolic effectsQ71600930
The pharmacokinetics of valproic acid after oral and parenteral administration in healthy volunteersQ71601113
Sodium valproate in the induction of unusual hepatotoxicityQ71619324
Use of stable labelled carbamazepine to study its kinetics during chronic carbamazepine treatmentQ71634302
The Influence of Folic Acid on Phenytoin (DPH) Metabolism and the 24-Hours Fluctuation in Urinary Output of 5-(p-hydroxyphenyl)-5 phenyl-hydantoin (HPPH)Q71739639
Diphenylhydantoin: Placental transport, fetallocalization, neonatal metabolism, and possible teratogenic effectsQ71748588
Carbamazepine-induced acceleration of diphenylhydantoin and warfarin metabolism in manQ71817059
Intravenous diphenylhydantoin in experimental seizures. II. Effect on penicillin-induced seizures in the catQ72040993
Sodium valproate: pharmacokinetics and effectivensss in treating intractable seizuresQ72124403
Effect of single doses of sodium valproate on serum phenytoin levels and protein binding in epileptic patientsQ72124686
Comparison of blood levels with oral and intramuscular diphenylhydantoinQ72137960
Disulfiramum (antabuse) as inhibitor of phenytoin metabolismQ72189817
Metabolic disposition of diphenylhydantoin in normal human subiects following intravenous administrationQ72409480
Fatal hepatotoxicity in child on phenobarbitone and sodium valproateQ72422655
Decreased serum protein binding of phenytoin in late pregnancyQ72428920
Changes in Regional Brain Levels of Amino Acid Putative Neurotransmitters After Prolonged Treatment with t he Anticonvulsant Drugs Diphenylhydantoin, Phenobarbitone, Sodium Valproate, Ethosuximide, and Sulthiame in the RatQ72450245
The influence of phenobarbital on the half-life of diphenylhydantoin in manQ72453869
Salivary levels of anticonvulsants: A practical approach to drug monitoringQ39145895
Excretion of antiepileptic drugs in sweatQ39220508
The effects of phenytoin on phenobarbitone and primidone metabolismQ39246208
Metabolic fate of phenobarbital in man. N-Glucoside formationQ39281125
Plasma binding of benzodiazepines in humansQ39288625
Phenytoin intoxication during concurrent diazepam therapyQ39322301
Digital hypoplasia and anticonvulsants during pregnancyQ39322541
Interactions of Antiepileptic DrugsQ39336953
Letter: Association between maternal intake of diazepam and oral cleftsQ39343232
Letter: Carbamazepine and mother's milkQ39343763
Letter: Diazepam and plasma-testosterone levelsQ39343945
Letter: Pyridoxine and serum concentration of phenytoin and phenobarbitoneQ39367386
Anticonvulsants and parental epilepsy in the development of birth defectsQ39367479
Therapeutic and pharmacokinetic effects of increasing phenytoin in chronic epileptics on multiple drug therapyQ39467929
Pharmacokinetics of drugs used for petit mal 'absence' epilepsyQ39620278
Ethosuximide Pharmacokinetics in a Pregnant Patient and Her NewbornQ39644374
Identification of Metabolites of Valproic Acid in Serum of Humans, Dog, Rat, and MouseQ39644385
Which Anticonvulsant Drug?Q39670675
Pharmacological Interactions of Mesuximide with Phenobarbital and Phenytoin in Hospitalized Epileptic PatientsQ39670698
Pancreatitis associated with valproic acid therapyQ39690628
Clinical Pharmacokinetics of DiazepamQ39720641
Clinical Pharmacokinetics of PhenytoinQ39806205
Biochemical and genetic factors regulating dilantin metabolism in man.Q39866492
Anticonvulsant drugs. II. Clinical pharmacological and therapeutic aspects.Q39956570
Pharmacokinetics of Carbamazepine in ManQ40061423
Phenytoin hepatotoxicity: a case report and reviewQ40065194
Electrophysiological actions of benzodiazepinesQ40121993
Adverse effects of phenytoin on peripheral nerves and neuromuscular junction: a reviewQ40125639
Clinical pharmacokinetics of valproic acidQ40257001
Use of antiepileptic drugs in the presence of liver and kidney diseases: a reviewQ40266496
Drug interactions with valproic acidQ40267248
Plasma protein binding of phenytoin in health and disease: relevance to therapeutic drug monitoring.Q40304319
Antiepileptic drugs: pharmacokinetic and clinical aspects.Q40306490
Clinical pharmacokinetics of nitrazepamQ40325640
Pharmacokinetic interactions with antiepileptic drugsQ40329711
Clinical pharmacokinetics of anticonvulsantsQ40640508
Use of saliva in therapeutic drug monitoringQ40744854
Disposition of diazepam and its major metabolite desmethyldiazepam in patients with liver diseaseQ40755891
Pharmacokinetics and bioavailability of sodium valproateQ40771960
Valproate sodium: a controlled clinical trial including monitoring of drug levelsQ40780318
Disposition of valproic acid in manQ40828077
Serum protein binding and pharmacokinetics of valproate in man, dog, rat and mouseQ40849017
Clinical Pharmacokinetics of CarbamazepineQ40877361
Plasma protein binding of valproic acid in healthy subjects and in patients with renal diseaseQ40897047
Rectal administration of sodium valproate in status epilepticusQ40936859
Sodium Valproate Increases Potassium Conductance in Aplysia NeuronsQ40943508
Plasma concentration of diazepam and N-desmethyldiazepam in children after a single rectal or intramuscular dose of diazepamQ40977564
Pharmacokinetics of carbamazepine in normal humans after single and repeated oral dosesQ46384348
Diphenylhydantoin elimination kinetics in overdosed childrenQ46920136
Lymphocytic Thyroiditis Possibly Induced by DiphenylhydantoinQ47784423
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbitalQ47853247
Serum Copper Levels and DiphenylhydantoinQ47885399
Plasma protein binding of diphenylhydantoin. Effects of sex hormones, renal and hepatic diseaseQ47886443
Effect of phenobarbital on hyperlipemia in patients with intrahepatic and extrahepatic cholestasisQ47987421
Coagulation defects caused by diphenylhydantoinQ48026089
Unit activity of amygdala and hippocampal neurons: effects of morphine and benzodiazepinesQ48292670
The mechanism of action of diphenylhydantoin or invertebrate neurons. I. Effects on basic membrane propertiesQ48316952
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patientsQ48435790
Facial clefts among epileptic patientsQ48664838
Further observations on the interactions between phenobarbital and diphenylhydantoin during chronic treatment in the rat.Q48794232
Species difference in diazepam metabolism and anticonvulsant effectQ49129886
Water intoxication due to carbamazepineQ49201789
Kinetics of phenobarbital in normal subjects and epileptic patientsQ50124195
Interaction of phenytoin and primidoneQ50321162
Induction of sex hormone binding globulin by phenytoinQ50328328
Effects of trimethadione, diphenylhydantoin and chlordiazepoxide on after-discharges in brain of cat.Q51287177
Brain 5-hydroxytryptamine and anticonvulsant activity.Q51295339
The renal origin of sodium valproate-induced hyperammonemia in fasting humans.Q51645961
Effect of Diphenylhydantoin on Insulin Secretion in ManQ51680621
Barbiturates: active form and site of action at node of Ranvier sodium channels.Q51867123
Serum protein binding of drugs during and after pregnancy in humans.Q51875039
Diazepam disposition determinants.Q51877437
Induction Effect of Diazepam on its Own MetabolismQ52113656
Explanation of dose-dependent decline of diphenylhydantoin plasma levels by fitting to the integrated form of the Michaelis-Menten equationQ52439737
Pharmacological implications of microsomal enzyme induction.Q52474261
Diazepam concentrations in parotid saliva, mixed saliva, and plasmaQ52704364
Human pharmacokinetics and bioavailability of temazepam administered in soft gelatin capsulesQ52707594
Pharmacokinetics of diazepam following multiple-dose oral administration to healthy human subjectsQ52708114
Plasma protein binding of diazepam and tolbutamide in chronic alcoholics.Q52712237
Letter: Association between maternal intake of diazepam and oral clefts.Q52714787
Clinical applications of gas chromatograph/mass spectrometer/computer systemsQ52716391
Diazepam metabolism in normal man. I. Serum concentrations and clinical effects after intravenous, intramuscular, and oral administration.Q52722036
Letter: Concentrations of diazepam in adipose tissue of children.Q52725352
Pharmacokinetic profile of diazepam in man following single intravenous and oral and chronic oral administrations.Q52727393
The effect of certain drugs on the plasma protein binding of phenytoin.Q52728947
Diazepam and breast-feeding.Q52734101
Interaction between phenytoin and the benzodiazepinesQ52739204
Salivary phenytoin radioimmunoassay. A simple method of the assessment of non-protein bound drug concentrationsQ67541167
Acetazolamide-induced interference with primidone absorption. Case reports and metabolic studiesQ67546732
Carbamazepine and its 10,11-epoxide in children and adults with epilepsyQ67549281
Kinetics of primidone metabolism and excretion in childrenQ67599335
The influences of phenytoin on the fundamental electrical properties of simple neural systemsQ67653587
Pharmacokinetics of nitrazepam in young volunteers and aged patients [proceedings]Q67691177
Effectiveness of prednisolone during phenytoin therapyQ67711046
Plasma levels of carbamazepine and carbamazepine-10,11-epoxide during treatment of epilepsyQ67826136
Immunoglobulin abnormalities in epileptic patients treated with diphenylhydantoinQ67826415
The elimination of phenytoin in manQ67832201
Two-fold interindividual variation in plasma protein binding of phenytoin in patients with epilepsyQ68266365
The effects of phenobarbitone dose on plasma phenobarbitone levels in epileptic patientsQ68275108
Characterization of the binding of benzodiazepines to human serum albuminQ68522466
[On resorption and distribution of methyl-ethyl-succinimide (MES) in serum and cerebrospinal fluid in children]Q68577042
Drug--interaction between sulthiame (Ospolot (R)) and phenytoin in the treatment of epilepsyQ68742729
Plasma protein binding of diphenylhydantoin in man. Interaction with other drugs and the effect of temperature and plasma dilutionQ68749158
Pulmonary function loss in diphenylhydantoin therapyQ68819488
Metabolism of branched medium chain length fatty acid. I. Omega-oxidation of sodium dipropylacetate in ratsQ68856021
Preliminary observations on the clinical pharmacology of carbamazepine ('Tegretol')Q68920165
Effects of Age, Sex, Obesity, and Pregnancy on Plasma Diphenylhydantoin LevelsQ68926969
Studies on plasma protein binding of carbamazepineQ68929708
The concentration of carbamazepine (Tegretol R) in serum and in cerebrospinal fluid in patients with epilepsyQ69022255
Experiences with Bivotril in treatment of epilepsy--particularly minor motor epilepsy--in mentally retarded childrenQ69033138
Anticonvulsant-induced antinuclear antibodiesand lupus-like disease in childrenQ69218005
Interaction between Doxycycline and some Antiepileptic DrugsQ69351369
Variation in Response to Anticonvulsants in a Group of Epileptic PatientsQ69375981
Phenylethylmalonamide (PEMA). An important metabolite of primidoneQ69375985
The absorption and excretion of ethosuximideQ69572251
Diphenylhydantoin-induced Gingival Hyperplasia: its Relationship to Dose and Serum LevelQ69575135
Studies on the disposition of the anticonvulsant clonazepam in the organisms of rat, dog, and manQ69586772
The Teratological Effects of Anticonvulsants and the Effects on Pregnancy and BirthQ69623751
Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsyQ69646920
Diphenylhydantoin dosageQ69688052
Pharmacokinetic profiles of clonazepam in dog and humans and of flunitrazepam in dogQ69764577
Subnormal serum folate due to anticonvulsive therapy. A double-blind study of the effect of folic acid treatment in patients with drug-induced subnormal serum folatesQ69894300
Dicoumarol-induced diphenylhydantoin intoxicationQ70066287
Phenylbutazone and isoniazid metabolism in patients with liver disease in relation to previous drug therapyQ70086060
Effect of anticonvulsant drugs on dicophane (D.D.T.) residues in manQ70111648
Ethosuximide in tears, saliva, and cerebrospinal fluidQ70222467
Age and phenytoin kinetics in adult epilepticsQ70283751
Plasma protein binding of diphenylhydantoin in patients with epilepsy. Agreement between the unbound fraction in plasma and the concentration in the cerebrospinal fluidQ70347852
Factors involved in an outbreak of phenytoin intoxicationQ70428736
Valproic acid in pregnancy--association with spina bifida: a preliminary reportQ70430290
Electrophysiological effects of diphenylhydantoin and carbamazepine on the peripheral and central nervous systemQ70442508
Free level monitoring of antiepileptic drugs. Clinical usefulness and case studiesQ70470596
Isoniazid-induced carbamazepine toxicity and vice versa: a double drug interactionQ70490780
Plasma protein binding of diphenylhydantoin in normal and hyperbilirubinemic infantsQ70560587
Malignant lymphogranulomatosis and anticonvulsant therapyQ70604543
Folic acid deficiency in patients receiving anticonvulsant drugsQ70621565
Age differences in drug binding by plasma proteins: Studies on human foetuses, neonates and adultsQ70681355
Carbamazepine plasma levels in children and adults: influence of age, dose, and associated therapyQ70744771
Pharmacokinetics and bioavailability of methylphenobarbital in manQ70778036
Influence of phenobarbital treatment on cimetidine kineticsQ70792982
P433issue4
P304page(s)328-363
P577publication date1984-04-01
P1433published inDrugsQ3040094
P1476titleAnticonvulsant drugs. An update
P478volume27

Reverse relations

cites work (P2860)
Q39502944Antiepileptic drug toxicity: definition and mechanism of action
Q42686092Carbamazepine-induced drowsiness
Q38720361Decreased phenytoin levels in patients receiving chemotherapy
Q51063182Design, synthesis and evaluation of 5-substituted 1-H-tetrazoles as potent anticonvulsant agents.
Q41615135Drug management of hypertensive disorders of pregnancy
Q40589552Drug-induced bone disease.
Q43229323Effect of sodium valproate on carbamazepine disposition and psychomotor profile in man.
Q39754383Free drug concentration monitoring in clinical practice. Rationale and current status
Q39548978Guide to drug dosage in renal failure
Q36024842Hypersensitivity reactions to procarbazine with mechlorethamine, vincristine, and procarbazine chemotherapy in the treatment of glioma
Q44239661N-, alpha-, and beta-Substituted 3-Aminopropionic acids: design, syntheses and antiseizure activities.
Q70992420Neither dosage nor serum levels of antiepileptic drugs are predictive for efficacy and adverse effects
Q43672688Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities
Q39675361The risk-benefit ratio of anticonvulsant drugs

Search more.