Plasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple doses

scientific article published on June 13, 1975

Plasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple doses is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF00562659
P953full work available at URLhttp://link.springer.com/content/pdf/10.1007/BF00562659.pdf
http://link.springer.com/article/10.1007/BF00562659/fulltext.html
http://link.springer.com/content/pdf/10.1007/BF00562659
P698PubMed publication ID1233232

P2093author name stringM. Eichelbaum
L. Bertilsson
A. Rane
K. Ekbom
V. A. Ringberger
P2860cites workShortcomings in Pharmacokinetic Analysis by Conceiving the Body to Exhibit Properties of a Single CompartmentQ56166237
Blood Levels of Drug at the Equilibrium State after Multiple DosingQ59056466
Determination of carbamazepine and its epoxide metabolite in plasma by high-speed liquid chromatographyQ66913495
Carbamazepine for epilepsy. A controlled prospective evaluationQ67288336
Distribution and elimination kinetics of carbamazepine in manQ67396517
Plasma levels of carbamazepine and carbamazepine-10,11-epoxide during treatment of epilepsyQ67826136
Concentration of carbamazepine (Tegretol) in serum and in cerebrospinal fluid in patients with epilepsyQ69038607
Quantitative determination of carbamazepine in plasma by mass fragmentographyQ69304659
Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsyQ69646920
A micromethod for the determination of carbamazepine in blood by high speed liquid chromatographyQ69718675
Carbamazepine in the Treatment of Tabetic Lightning PainsQ70343321
Mass Spectrometric Characterization of Carbamazepine-10,11-epoxide,a Carbamazepine Metabolite Isolated from Human UrineQ70420847
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpharmacologyQ128406
carbamazepinQ410412
P304page(s)337-341
P577publication date1975-06-01
1975-06-13
P1433published inEuropean Journal of Clinical PharmacologyQ1376707
P1476titlePlasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple doses
P478volume8

Reverse relations

cites work (P2860)
Q52222033A comparison between direct determination of in vivo dissolution and the deconvolution technique in humans.
Q28327950A comparison of the efficacy and tolerability of controlled-release carbamazepine with conventional carbamazepine
Q34397398A double-blind comparison of conventional and controlled-release carbamazepine in healthy subjects
Q40142216Anticonvulsant drugs. An update
Q34270748Anticonvulsants during pregnancy and lactation. Transplacental, maternal and neonatal pharmacokinetics
Q40796225Antiepileptic medication interactions.
Q40265358Antiepileptic therapeutic drug monitoring.
Q40267429Application of stable labelled drugs in clinical pharmacokinetic investigations
Q36603317Association of carbamazepine major metabolism and transport pathway gene polymorphisms and pharmacokinetics in patients with epilepsy
Q40962396Bioavailability of Four Different Pharmaceutical Preparations of Carbamazepine
Q36364659Bioequivalence of oral and intravenous carbamazepine formulations in adult patients with epilepsy
Q48146588Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients
Q67549281Carbamazepine and its 10,11-epoxide in children and adults with epilepsy
Q46338118Carbamazepine clearance in paediatric epilepsy patients. Influence of body mass, dose, sex and co-medication
Q34987488Carbamazepine dose-frequency requirement in children
Q41112491Carbamazepine intoxication caused by interaction with isoniazid.
Q70058771Carbamazepine metabolism in man. Induction and pharmacogenetic aspects
Q40895629Carbamazepine overdose. Features of 33 cases
Q36706570Carbamazepine substitution in severe partial epilepsy: implication of autoinduction of metabolism
Q38627226Carbamazepine toxicity and poisoning. Incidence, clinical features and management
Q34156256Characterization of the time course of carbamazepine deinduction by an enzyme turnover model
Q40877361Clinical Pharmacokinetics of Carbamazepine
Q39738819Clinical pharmacokinetics and pharmacological effects of carbamazepine and carbamazepine-10,11-epoxide. An update
Q68249146Clinical pharmacokinetics in infants and children
Q34403438Clinically significant pharmacokinetic drug interactions with carbamazepine. An update
Q67029707Comparative bioavailability of two commercial preparations of carbamazepine tablets
Q50153894Comparison of the pharmacokinetics of diazepam after single and subchronic doses
Q62782509Computer analysis of saccadic eye movements: assessment of two different carbamazepine formulations
Q35078847Diseases Affecting Bone Quality: Beyond Osteoporosis
Q44487652Disposition of placentally transferred carbamazepine (Tegretol�) in the newborn
Q40828077Disposition of valproic acid in man
Q34345745Double dummy comparison between once and twice daily dosing with modified-release carbamazepine in epileptic patients
Q38914642Drug level monitoring in paediatric practice
Q72589317Early stage autoinduction of carbamazepine metabolism in humans
Q43989983Effect of denzimol on carbamazepine and carbamazepine-10,11-epoxide concentrations in serum, liver, spleen and different brain regions of the rat: an inhibitory metabolic interaction
Q71763110Effect of dosage frequency of carbamazepine on drug serum levels in epileptic patients
Q70188687Effect of vitamin D2and D3on bone-mineral content in carbamazepine-treated epileptic patients
Q37322108Effects of antiepileptic drugs on hippocampal neurons coupled to micro-electrode arrays
Q42531502Effects of cimetidine on carbamazepine auto- and hetero-induction in man.
Q41789144Encephalopathy and Brain Stem Dysfunction in an Infant With Non-Accidental Carbamazepine Intoxication
Q46564322Enhanced clearance of carbamazepine using albumin-containing dialysate during CVVHDF.
Q60586286Epileptic patients refractory to drug therapy
Q42699921Hepatic enzyme induction and leucocyte delta-aminolaevulinic acid synthase activity: studies with carbamazepine
Q24811056Incorporating children's toxicokinetics into a risk framework
Q35827686Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants
Q41917893Lack of enzyme induction with oxcarbazepine (600 mg daily) in healthy subjects
Q72577574Long-term observation of the relation between pain intensity and serum carbamazepine concentration in elderly patients with trigeminal neuralgia
Q41149339Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring
Q39661008Pharmacokinetic Description of Drug Interactions by Enzyme Induction: Carbamazepine-Clonazepam in Monkeys
Q67445131Pharmacokinetic Model to Describe Self‐Induced Decreases in Steady‐State Concentrations of Carbamazepine
Q39074126Pharmacokinetics and Pharmacogenetics of Carbamazepine in Children
Q35759107Pharmacokinetics of drugs in overdose
Q34622792Pharmacokinetics of primaquine in man. II. Comparison of acute vs chronic dosage in Thai subjects
Q28329448Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure
Q40640453Plasma level monitoring of anticonvulsants
Q67826136Plasma levels of carbamazepine and carbamazepine-10,11-epoxide during treatment of epilepsy
Q36430811Poor correlation between single-dose data and steady-state kinetics for phenobarbitone, primidone, carbamazepine and sodium valproate in children during monotherapy. Possible reasons for the lack of correlation
Q40083637Psychopharmacological aspects of antiepileptic treatment
Q36446899Safety and tolerability of mood-stabilising anticonvulsants in the elderly
Q43241380Saliva carbamazepine levels in children before and during multiple dosing
Q34448908Salivary concentrations and plasma protein binding of carbamazepine and carbamazepine 10,11-epoxide in epileptic patients
Q45105829Serum Concentration of Carbamazepine: Comparison of Herrmann's Spectrophotometric Method and a New GLC Method for the Determination of Carbamazepine
Q44929720Simulated fluctuations in plasma drug concentrations for patients receiving oxcarbazepine or carbamazepine extended-release capsules
Q44640235Simulation of the effect of patient nonadherence on plasma concentrations of carbamazepine from twice-daily extended-release capsules
Q71242227Simultaneous liquid chromatographic analysis for carbamazepine and carbamazepine 10,11-epoxide in plasma and saliva by use of double internal standardization
Q69395064Simultaneous quantitation of salivary carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbitone by high-performance liquid chromatography
Q66997369Simultaneous, rapid high-performance liquid chromatographic microanalysis of plasma carbamazepine and its 10,11-epoxide metabolite: applications to pharmacokinetic studies in humans
Q33683890Steady-state carbamazepine pharmacokinetics following oral and stable-labeled intravenous administration in epilepsy patients: effects of race and sex
Q44584927The Pharmacokinetics of Carbamazepine in Plasma and Saliva of Man
Q71049227The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile
Q67052582The pharmacokinetics of carbamazepine
Q35174228The use of gabapentin for the treatment of postherpetic neuralgia
Q41690929Time course of carbamazepine self-induction
Q71634302Use of stable labelled carbamazepine to study its kinetics during chronic carbamazepine treatment

Search more.