A comparison between direct determination of in vivo dissolution and the deconvolution technique in humans

scientific article published in April 1999

A comparison between direct determination of in vivo dissolution and the deconvolution technique in humans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0928-0987(98)00055-4
P698PubMed publication ID10072475

P2093author name stringLindahl A
Kristensen HG
Hovgaard L
Knutson L
Bønløkke L
Lennernäs H
P2860cites workA theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailabilityQ28293773
Per Cent Absorbed Time Plots Derived from Blood Level and/or Urinary Excretion DataQ30859110
Clinical Pharmacokinetics of CarbamazepineQ40877361
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 2. Phase analysis and aggregation states of luminal lipids during duodenal fat digestion in healthy adult human beingsQ41228115
Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.Q41364364
Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage formsQ41714891
Pharmacokinetics of carbamazepine in normal manQ42102627
Physiologic Surface-Active Agents and Drug Absorption IV: Effect of Pre-Micellar Concentrations of Surfactant on Dissolution RateQ47786714
Characterization of fluids from the stomach and proximal jejunum in men and womenQ50956608
Distribution and elimination kinetics of carbamazepine in manQ67396517
Plasma kinetics of carbamazepine and its epoxide metabolite in man after single and multiple dosesQ67396551
Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in manQ67591105
Solubilization and wetting effects of bile salts on the dissolution of steroidsQ67882536
The bioinequivalence of carbamazepine tablets with a history of clinical failuresQ67994620
Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1. Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beingsQ68758865
Simultaneous measurement of phenobarbital, carbamazepine, phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in serum by high-performance liquid chromatographyQ68980886
Gastrointestinal bioavailability: determination of in vivo release profiles of solid oral dosage forms by deconvolutionQ69804437
Jejunal permeability and hepatic extraction of fluvastatin in humansQ71828066
Studies on Absorption and Excretion of Drug. VII. A New Estimation Method for the Release of Drugs from Dosage Forms and the Availability in vivoQ71858518
A Residence-Time Distribution Analysis of the Hydrodynamics within the Intestine in Man during a Regional Single-pass Perfusion with Loc-I-Gut: In-vivo Permeability EstimationQ73584101
A new approach for direct in vivo dissolution studies of poorly soluble drugsQ73849620
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectdeconvolutionQ1183700
P304page(s)19-27
P577publication date1999-04-01
P1433published inEuropean Journal of Pharmaceutical SciencesQ5412738
P1476titleA comparison between direct determination of in vivo dissolution and the deconvolution technique in humans
P478volume8

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cites work (P2860)
Q51950534A clinical single-pass perfusion investigation of the dynamic in vivo secretory response to a dietary meal in human proximal small intestine.
Q37631534Comparative in vitro dissolution study of carbamazepine immediate-release products using the USP paddles method and the flow-through cell system
Q46651828Determination of intraluminal theophylline concentrations after oral intake of an immediate- and a slow-release dosage form.
Q42638823Direct estimation of the in vivo dissolution of spironolactone, in two particle size ranges, using the single-pass perfusion technique (Loc-I-Gut) in humans
Q51557252Dissolution of hydrocortisone in human and simulated intestinal fluids
Q43164713Effect of a single gemfibrozil dose on the pharmacokinetics of rosuvastatin in bile and plasma in healthy volunteers
Q42207382Influence of drug release properties of conventional solid dosage forms on the systemic exposure of highly soluble drugs
Q39846636Predicting intestinal precipitation--a case example for a basic BCS class II drug
Q52005114Quantitative biopharmaceutics classification system: the central role of dose/solubility ratio

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