| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.YEXCR.2006.12.011 |
| P698 | PubMed publication ID | 17291493 |
| P50 | author | José Antonio Rodríguez | Q55138167 |
| Frank P Vleggaar | Q64616760 | ||
| Giuseppe Giaccone | Q37829946 | ||
| P2093 | author name string | Agnieszka Checinska | |
| Bas S J Hoogeland | |||
| P2860 | cites work | TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells | Q21260428 |
| Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner | Q22008727 | ||
| An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 | Q22009407 | ||
| Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1 | Q24290112 | ||
| Structural basis of caspase-7 inhibition by XIAP | Q24290942 | ||
| Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain | Q24290943 | ||
| Structural basis for the inhibition of caspase-3 by XIAP | Q24290945 | ||
| Mechanism of XIAP-mediated inhibition of caspase-9 | Q24296916 | ||
| The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases | Q24532851 | ||
| IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases | Q24533214 | ||
| NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP | Q27626381 | ||
| The Hallmarks of Cancer | Q221226 | ||
| Expression and localization of inhibitor of apoptosis proteins in normal human tissues | Q81637512 | ||
| Structural and biochemical basis of apoptotic activation by Smac/DIABLO | Q27626899 | ||
| Structural basis of IAP recognition by Smac/DIABLO | Q27629148 | ||
| A system for stable expression of short interfering RNAs in mammalian cells | Q27860875 | ||
| Mammalian caspases: structure, activation, substrates, and functions during apoptosis | Q28139429 | ||
| Mechanisms of caspase activation | Q28187994 | ||
| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis | Q28204205 | ||
| Apoptosis in the pathogenesis and treatment of disease | Q28235731 | ||
| IAP family proteins--suppressors of apoptosis | Q28297514 | ||
| The biochemistry of apoptosis | Q29547741 | ||
| IAP proteins: blocking the road to death's door | Q29619844 | ||
| Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes | Q30830747 | ||
| Inactivation of the apoptosis effector Apaf-1 in malignant melanoma | Q31984891 | ||
| Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells | Q33200961 | ||
| Caspase activation: the induced-proximity model | Q33740126 | ||
| DNA damage-induced apoptosis | Q34312499 | ||
| A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death | Q34346499 | ||
| Lung cancer--a philosophical, ethical, and personal perspective | Q34420832 | ||
| Apoptosis-targeted therapies for cancer | Q35057060 | ||
| Direct activation of the apoptosis machinery as a mechanism to target cancer cells | Q35145998 | ||
| Alterations in the apoptotic machinery and their potential role in anticancer drug resistance | Q35567264 | ||
| Genomic surgery for lung cancer | Q35688050 | ||
| Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks | Q35743146 | ||
| Caspase activation, inhibition, and reactivation: a mechanistic view | Q35845173 | ||
| Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology | Q35874476 | ||
| Synthetic Smac peptide enhances the effect of etoposide-induced apoptosis in human glioblastoma cell lines | Q40297721 | ||
| The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases | Q40341729 | ||
| Inhibition of clonogenic tumor growth: a novel function of Smac contributing to its antitumor activity | Q40386827 | ||
| XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs. | Q40470946 | ||
| Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics | Q40513940 | ||
| Caspase-9 can be activated without proteolytic processing | Q40966257 | ||
| Caspases: key mediators of apoptosis | Q41760384 | ||
| IAP proteins: sticking it to Smac | Q42813655 | ||
| Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ | Q44129457 | ||
| Role of Smac in human leukaemic cell apoptosis and proliferation | Q44365692 | ||
| A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells | Q46619108 | ||
| Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients. | Q52590107 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | chemotherapy | Q974135 |
| P304 | page(s) | 1215-1224 | |
| P577 | publication date | 2006-12-29 | |
| P1433 | published in | Experimental Cell Research | Q1524289 |
| P1476 | title | Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation | |
| P478 | volume | 313 |
| Q33961325 | BV6, an IAP antagonist, activates apoptosis and enhances radiosensitization of non-small cell lung carcinoma in vitro |
| Q91815478 | Benzyl Isothiocyanate Induces Apoptosis via Reactive Oxygen Species-Initiated Mitochondrial Dysfunction and DR4 and DR5 Death Receptor Activation in Gastric Adenocarcinoma Cells |
| Q33637043 | Differential sensitivity to apoptosome apparatus activation in non-small cell lung carcinoma and the lung |
| Q39010266 | Effect of Smac and Taxol on non-small-cell lung cancer |
| Q38763961 | Embelin prevents LMP1-induced TRAIL resistance via inhibition of XIAP in nasopharyngeal carcinoma cells |
| Q26801037 | Harnessing the apoptotic programs in cancer stem-like cells |
| Q42755801 | Heterotrimeric stimulatory GTP-binding proteins inhibit cisplatin-induced apoptosis by increasing X-linked inhibitor of apoptosis protein expression in cervical cancer cells |
| Q81140440 | Immunohistochemical detection of XIAP and p63 in adenomatous hyperplasia, atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and well-differentiated adenocarcinoma |
| Q47148201 | Immunohistochemical expression of X-linked inhibitor of apoptosis in eyelid sebaceous gland carcinoma predicts a worse prognosis |
| Q37313817 | Microarray-based cancer prediction using soft computing approach |
| Q41181776 | Nephroprotective Effects of Saponins from Leaves of Panax quinquefolius against Cisplatin-Induced Acute Kidney Injury |
| Q35933632 | Nicotine Inhibits Cisplatin-Induced Apoptosis via Regulating α5-nAChR/AKT Signaling in Human Gastric Cancer Cells |
| Q34545482 | Resistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance |
| Q39664088 | Sensitization of human bladder tumor cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis with a small molecule IAP antagonist |
| Q34556212 | Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer |
| Q38815692 | Synergistic antitumor activity of pro-apoptotic agent PAC-1 with cisplatinum by the activation of CASP3 in pulmonary adenocarcinoma cell line H1299. |
| Q28396304 | Tumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancer |
| Q43777713 | cIAP2 Upregulated by E6 Oncoprotein via Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/AKT Pathway Confers Resistance to Cisplatin in Human Papillomavirus 16/18–Infected Lung Cancer |
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