TRPV1 is a novel target for omega-3 polyunsaturated fatty acids

scientific article published on 12 October 2006

TRPV1 is a novel target for omega-3 polyunsaturated fatty acids is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1113/JPHYSIOL.2006.121988
P932PMC publication ID2075157
P698PubMed publication ID17038422
P5875ResearchGate publication ID6757803

P2093author name stringRosa L Miyares
Gerard P Ahern
José A Matta
P2860cites workThe capsaicin receptor: a heat-activated ion channel in the pain pathwayQ24322558
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptorsQ24534526
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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.Q27863762
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Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesiaQ28144926
The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)Q28343961
Polyunsaturated fatty acids are potent neuroprotectorsQ28344163
Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substancesQ28344313
Protein kinase C activation potentiates gating of the vanilloid receptor VR1 by capsaicin, protons, heat and anandamideQ28345160
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamideQ28370516
Impaired nociception and pain sensation in mice lacking the capsaicin receptorQ28511370
Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1Q28582473
Anxiety and adipose essential fatty acid precursors for prostaglandin E1 and E2Q28645876
The cloned capsaicin receptor integrates multiple pain-producing stimuliQ29547511
Vanilloid (Capsaicin) receptors and mechanismsQ29617371
Mechanisms of action of docosahexaenoic acid in the nervous systemQ30666183
Omega-3 fatty acids and bipolar disorder: a reviewQ33724974
Blocking effects of polyunsaturated fatty acids on Na+ channels of neonatal rat ventricular myocytesQ33749115
A spinal mechanism of action is involved in the antinociception produced by the capsaicin analogue NE 19550 (olvanil)Q68688570
Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysisQ71133156
Irreversible impairment of thermoregulation induced by capsaicin and similar pungent substances in rats and guinea-pigsQ71639762
Intranigral injection of capsaicin enhances motor activity and depletes nigral 5-hydroxytryptamine but not substance PQ72648217
n-3 fatty acids and cysteinyl-leukotriene formation in humans in vitro, ex vivo, and in vivoQ72949385
Voltage- and time-dependent properties of the recombinant rat vanilloid receptor (rVR1)Q73900902
A study of the voltage dependence of capsaicin-activated membrane currents in rat sensory neurones before and after acute desensitizationQ78040201
Polyunsaturated fatty acids and inflammatory bowel disease.Q33807441
Fish, meat, and risk of dementia: cohort studyQ33962080
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omega 3 polyunsaturated fatty acids, inflammation and immunityQ34589602
Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophilsQ34621152
Could n-3 polyunsaturated fatty acids reduce pathological pain by direct actions on the nervous system?Q35067994
Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and humanQ35120095
Prevention of sudden cardiac death by n-3 polyunsaturated fatty acidsQ35143363
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Neurobehavioral aspects of omega-3 fatty acids: possible mechanisms and therapeutic value in major depression.Q35599565
Docosahexaenoic acid, fatty acid-interacting proteins, and neuronal function: breastmilk and fish are good for you.Q36280370
Membrane cholesterol content modulates activation of volume-regulated anion current in bovine endothelial cellsQ36444953
Modulation of learning, pain thresholds, and thermoregulation in the rat by preparations of free purified alpha-linolenic and linoleic acids: determination of the optimal omega 3-to-omega 6 ratioQ36648661
Polyunsaturated fatty acids modulate sodium and calcium currents in CA1 neuronsQ37243012
Lipoxygenase metabolites of arachidonic acid in neuronal transmembrane signallingQ37827767
Spring constants for channel-induced lipid bilayer deformations. Estimates using gramicidin channelsQ40137841
Chemistry and metabolism of lipids in the vertebrate retinaQ40154390
Endogenous unsaturated C18 N-acylethanolamines are vanilloid receptor (TRPV1) agonistsQ40388693
Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase.Q40461994
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channelsQ40526282
Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domainQ40583946
N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesiaQ40672731
Direct phosphorylation of capsaicin receptor VR1 by protein kinase Cepsilon and identification of two target serine residuesQ40746070
Enhancement of potency and efficacy of NADA by PKC-mediated phosphorylation of vanilloid receptorQ42457403
Variations of membrane cholesterol alter the kinetics of Ca2(+)-dependent K+ channels and membrane fluidity in vascular smooth muscle cellsQ42643858
Significantly reduced docosahexaenoic and docosapentaenoic acid concentrations in erythrocyte membranes from schizophrenic patients compared with a carefully matched control groupQ43546708
Plasma fatty acid levels in autistic childrenQ43696926
Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytesQ43744808
The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal sliceQ43826497
Voltage-dependent priming of rat vanilloid receptor: effects of agonist and protein kinase C activationQ44232772
Presynaptic Facilitation of Glutamatergic Synapses to Dopaminergic Neurons of the Rat Substantia Nigra by Endogenous Stimulation of Vanilloid ReceptorsQ44418969
Differential effects of intraplantar capsazepine and ruthenium red on capsaicin-induced desensitization in miceQ44448578
Activation of TRPV1 by the satiety factor oleoylethanolamideQ44449782
Letter: Fatty acids, platelets, and microcirculatory obstructionQ44636884
Activation of TRPV1 in the VTA excites dopaminergic neurons and increases chemical- and noxious-induced dopamine release in the nucleus accumbens.Q45161643
Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivoQ45193556
Oleoylethanolamide excites vagal sensory neurones, induces visceral pain and reduces short-term food intake in mice via capsaicin receptor TRPV1.Q45253646
Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling.Q46510733
Kinetics of penetration influence the apparent potency of vanilloids on TRPV1.Q46898008
The lipid composition of adult rat brain synaptosomal plasma membranesQ48752407
Capsaicin binds to the intracellular domain of the capsaicin-activated ion channelQ48925618
Attenuation of channel kinetics and conductance by cholesterol: an interpretation using structural stress as a unifying concept.Q50116041
A randomized double-blind, placebo-controlled study of the effects of supplementation with highly unsaturated fatty acids on ADHD-related symptoms in children with specific learning difficulties.Q52124551
The responses of rat trigeminal ganglion neurons to capsaicin and two nonpungent vanilloid receptor agonists, olvanil and glyceryl nonamide.Q52264064
Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL.Q52568167
Supplementation with omega-3 polyunsaturated fatty acids in the management of dysmenorrhea in adolescents.Q55066448
P433issuePt 2
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
P304page(s)397-411
P577publication date2006-10-12
P1433published inJournal of PhysiologyQ7743612
P1476titleTRPV1 is a novel target for omega-3 polyunsaturated fatty acids
P478volume578

Reverse relations

cites work (P2860)
Q58610880A hypothetical molecular mechanism for TRPV1 activation that invokes rotation of an S6 asparagine
Q57174612A mathematical and computational model of the calcium dynamics in Caenorhabditis elegans ASH sensory neuron
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Q37625453Actions and Mechanisms of Polyunsaturated Fatty Acids on Voltage-Gated Ion Channels
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Q39207848Constitutively active TRPC channels of adipocytes confer a mechanism for sensing dietary fatty acids and regulating adiponectin
Q37872360Deciphering the mechanism(s) of action of natural products: analgesic peroxide oil as example
Q39747897Direct activation of transient receptor potential V1 by nickel ions
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Q26996552Effects of docosahexaenoic Acid on neurotransmission
Q34851917Fish oil concentrate delays sensitivity to thermal nociception in mice
Q36379366Fish oil intake induces UCP1 upregulation in brown and white adipose tissue via the sympathetic nervous system.
Q37336009Inhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch.
Q35163419Intracellular long-chain acyl CoAs activate TRPV1 channels
Q34072039Linoleic acid inhibits TRP channels with intrinsic voltage sensitivity: Implications on the mechanism of linoleic acid action
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Q36593666Lipid bilayer-mediated regulation of ion channel function by amphiphilic drugs
Q47138350Long-Chain Omega-3 Fatty Acids Supplementation Accelerates Nerve Regeneration and Prevents Neuropathic Pain Behavior in Mice
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Q24644177TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons
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Q40068777Voltage is a partial activator of rat thermosensitive TRP channels

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