| scholarly article | Q13442814 |
| P2093 | author name string | Hiroshi Harada | |
| Masahiro Hiraoka | |||
| Shinae Kizaka-Kondoh | |||
| P2860 | cites work | Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein | Q29615928 |
| Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein | Q29615931 | ||
| Tumor hypoxia: a target for selective cancer therapy | Q35602696 | ||
| Caspase-9 regulation: an update | Q35802114 | ||
| Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. | Q36665942 | ||
| p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons | Q38290314 | ||
| Tumour suppression by the human von Hippel-Lindau gene product | Q41320477 | ||
| Adenovirus-mediated wild-type p53 tumor suppressor gene therapy induces apoptosis and suppresses growth of human pancreatic cancer [seecomments] | Q45854824 | ||
| Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. | Q53425055 | ||
| C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation | Q24291783 | ||
| A conserved family of prolyl-4-hydroxylases that modify HIF | Q24291794 | ||
| Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein | Q24599442 | ||
| Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex | Q24655274 | ||
| Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway | Q24672316 | ||
| Hypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathways | Q24804177 | ||
| Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 | Q28141355 | ||
| Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription | Q28187801 | ||
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hypoxia | Q105688 |
| cytotoxicity | Q246181 | ||
| P1104 | number of pages | 5 | |
| P304 | page(s) | 5718-5722 | |
| P577 | publication date | 2006-09-22 | |
| P1433 | published in | FEBS Letters | Q1388051 |
| P1476 | title | Mechanism of hypoxia-specific cytotoxicity of procaspase-3 fused with a VHL-mediated protein destruction motif of HIF-1alpha containing Pro564. | |
| P478 | volume | 580 |
| Q37307621 | A novel injectable BRET-based in vivo imaging probe for detecting the activity of hypoxia-inducible factor regulated by the ubiquitin-proteasome system |
| Q34079232 | Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging |
| Q53319606 | Genetic and epigenetic analysis of the VHL gene in gastric cancers. |
| Q34679148 | Hypoxia-induced human endonuclease G expression suppresses tumor growth in a xenograft model. |
| Q37170729 | Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model |
| Q39002822 | Hypoxia: A Double-Edged Sword in Cancer Therapy |
| Q39993165 | Imaging and Targeting of the Hypoxia-inducible Factor 1-active Microenvironment |
| Q33784382 | In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system |
| Q28484495 | In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion protein probe |
| Q36780880 | Involvement of decreased hypoxia-inducible factor 1 activity and resultant G1-S cell cycle transition in radioresistance of perinecrotic tumor cells. |
| Q30670722 | PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase |
| Q39856479 | Selective killing of hypoxia-inducible factor-1-active cells improves survival in a mouse model of invasive and metastatic pancreatic cancer |
| Q40120839 | Significance of HIF-1-active cells in angiogenesis and radioresistance |
| Q39934761 | TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1 activation and inducing endothelial cell apoptosis |
| Q41903043 | Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy |
| Q53272680 | Tumor Hypoxia Imaging |
| Q37641366 | Viral-based gene delivery and regulated gene expression for targeted cancer therapy |
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