Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties

scientific article published on 10 April 2017

Transcriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MICINF.2017.04.001
P932PMC publication ID5581956
P698PubMed publication ID28408270

P50authorCarlos J OrihuelaQ59689126
P2093author name stringHervé Tettelin
Timothy J Mitchell
Nikhil Kumar
Adonis D'Mello
Jesus Segovia
Anel Lizcano
Cecilia A Hinojosa
Anukul T Shenoy
Ryan P Gilley
Alison Maren Saville
Ramya Akula Suresh Babu
P2860cites workThe biological role of death and lysis in biofilm developmentQ36908387
Streptococcus pneumoniae biofilm formation is strain dependent, multifactorial, and associated with reduced invasiveness and immunoreactivity during colonizationQ37267085
The Streptococcus pneumoniae adhesin PsrP binds to Keratin 10 on lung cellsQ37366269
Large-scale identification of serotype 4 Streptococcus pneumoniae virulence factorsQ37459576
Four proteins encoded in the gspB-secY2A2 operon of Streptococcus gordonii mediate the intracellular glycosylation of the platelet-binding protein GspBQ37583358
Pour some sugar on it: the expanding world of bacterial protein O-linked glycosylationQ38107228
Antibodies against PsrP, a novel Streptococcus pneumoniae adhesin, block adhesion and protect mice against pneumococcal challengeQ39977826
The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrierQ41848341
A Streptococcus pneumoniae pathogenicity island encoding an ABC transporter involved in iron uptake and virulenceQ43612695
Deaths: leading causes for 2009.Q43829440
The Fap1 fimbrial adhesin is a glycoprotein: antibodies specific for the glycan moiety block the adhesion of Streptococcus parasanguis in an in vitro tooth modelQ43889745
Contribution of host, bacterial factors and antibiotic treatment to mortality in adult patients with bacteraemic pneumococcal pneumoniaQ43915808
An accessory sec locus of Streptococcus gordonii is required for export of the surface protein GspB and for normal levels of binding to human platelets.Q45947385
Defining the enzymatic pathway for polymorphic O-glycosylation of the pneumococcal serine-rich repeat protein PsrP.Q51118148
Zinc metalloproteinase genes in clinical isolates of Streptococcus pneumoniae: association of the full array with a clonal cluster comprising serotypes 8 and 11AQ62120581
Carbohydrate composition analysis of glycoconjugates by gas-liquid chromatography/mass spectrometryQ72319509
Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniaeQ22065841
The pneumococcal serine-rich repeat protein is an intra-species bacterial adhesin that promotes bacterial aggregation in vivo and in biofilmsQ27313860
The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formationQ27313982
Structural and Functional Analysis of a New Subfamily of Glycosyltransferases Required for Glycosylation of Serine-rich Streptococcal AdhesinsQ27666270
The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase foldQ27684682
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimatesQ28258300
Quantification of biofilm structures by the novel computer program comstatQ28547921
Regions of Diversity 8, 9 and 13 contribute to Streptococcus pneumoniae virulenceQ33295236
Interaction between two putative glycosyltransferases is required for glycosylation of a serine-rich streptococcal adhesinQ33310568
Glycosylation and biogenesis of a family of serine-rich bacterial adhesinsQ33406850
A self-deleting Cre-lox-ermAM cassette, Cheshire, for marker-less gene deletion in Streptococcus pneumoniaeQ33622445
Purification and Characterization of an Active N -Acetylglucosaminyltransferase Enzyme Complex from StreptococciQ33726747
A novel glucosyltransferase is required for glycosylation of a serine-rich adhesin and biofilm formation by Streptococcus parasanguinisQ33782553
Two additional components of the accessory sec system mediating export of the Streptococcus gordonii platelet-binding protein GspB.Q33788541
Streptococcus pneumoniae in biofilms are unable to cause invasive disease due to altered virulence determinant productionQ34103322
A role for glycosylated serine-rich repeat proteins in gram-positive bacterial pathogenesisQ34324594
Identification of a Candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal diseaseQ34975633
Interruption of capsule production in Streptococcus pneumonia serotype 3 by insertion of transposon Tn916.Q35104954
Cellular senescence increases expression of bacterial ligands in the lungs and is positively correlated with increased susceptibility to pneumococcal pneumoniaQ35214180
A molecular chaperone mediates a two-protein enzyme complex and glycosylation of serine-rich streptococcal adhesinsQ35266929
The Streptococcus gordonii platelet binding protein GspB undergoes glycosylation independently of exportQ35546776
The accessory Sec protein Asp2 modulates GlcNAc deposition onto the serine-rich repeat glycoprotein GspBQ36280988
P433issue6
P921main subjectRNA sequencingQ2542347
P304page(s)323-333
P577publication date2017-04-10
P1433published inMicrobes and InfectionQ15760242
P1476titleTranscriptional organization of pneumococcal psrP-secY2A2 and impact of GtfA and GtfB deletion on PsrP-associated virulence properties
P478volume19

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cites work (P2860)
Q96603921A multiple drug-resistant Streptococcus pneumoniae of serotype 15A occurring from serotype 19A by capsular switching
Q47232081How Sweet Are Our Gut Beneficial Bacteria? A Focus on Protein Glycosylation in Lactobacillus
Q91615974Serine-rich repeat proteins from gut microbes
Q55514832Streptococcus pneumoniae’s Virulence and Host Immunity: Aging, Diagnostics, and Prevention.

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