Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.

scientific article published on 24 January 2006

Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11010-005-9094-2
P698PubMed publication ID16432762
P5875ResearchGate publication ID7340265

P2093author name stringYan Xia
Colin S Duckett
Jennifer Lewis
Andrew C Phillips
Rachel Novak
P2860cites workApoptosis in disease: about shortage and excessQ35571007
Control of mitochondrial permeability by Bcl-2 family membersQ35680504
Baculovirus inhibitor of apoptosis functions at or upstream of the apoptotic suppressor P35 to prevent programmed cell deathQ35886664
Upon drug-induced apoptosis in lymphoma cells X-linked inhibitor of apoptosis (XIAP) translocates from the cytosol to the nucleusQ40516850
Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosisQ40593626
Inhibiting apoptosis in mammalian cell culture using the caspase inhibitor XIAP and deletion mutantsQ40755337
E2F-1 potentiates cell death by blocking antiapoptotic signaling pathwaysQ40908814
Differential requirement for caspase 9 in apoptotic pathways in vivo.Q41015558
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.Q41099375
Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: the role of caspase inhibitionQ47352262
Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expressionQ57248011
Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1Q62746016
Apoptosis. Mitochondria--the death signal integratorsQ74257381
Low expression of XIAP-associated factor 1 in human colorectal cancersQ81311988
Induction and redistribution of XAF1, a new antagonist of XIAP in the rat brain after transient focal ischemiaQ81766672
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerQ22008727
PUMA induces the rapid apoptosis of colorectal cancer cellsQ24291462
PUMA, a novel proapoptotic gene, is induced by p53Q24291463
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell deathQ24291746
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptorsQ24310559
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosisQ24310597
X-linked IAP is a direct inhibitor of cell-death proteasesQ24318710
The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteinsQ24532225
Upstream regulatory role for XIAP in receptor-mediated apoptosisQ24563793
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibitionQ28115131
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosisQ28144256
X-linked inhibitor of apoptosis protein (XIAP) inhibits caspase-3 and -7 in distinct modesQ28189754
Identification of XAF1 as an antagonist of XIAP anti-Caspase activityQ28200039
Puma is an essential mediator of p53-dependent and -independent apoptotic pathwaysQ28213279
Caspases: enemies withinQ29547315
Mitochondria and apoptosisQ29547905
IAP proteins: blocking the road to death's doorQ29619844
Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell linesQ30967010
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95LQ32152397
Characterization of XIAP-deficient miceQ33559119
Apoptosis control by death and decoy receptorsQ33597389
Identification of X-linked inhibitor of apoptosis-associated factor-1 as an interferon-stimulated gene that augments TRAIL Apo2L-induced apoptosisQ34130066
A new quantitative assay for cytochrome c release in apoptotic cells.Q34207175
Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomasQ34276095
XAF1 expression is significantly reduced in human melanomaQ34378197
Apoptotic pathways: the roads to ruinQ34753431
Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancerQ35157905
P433issue1-2
P304page(s)67-76
P577publication date2006-01-24
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleXaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.
P478volume286

Reverse relations

cites work (P2860)
Q39972640Adenoviral-mediated Rybp expression promotes tumor cell-specific apoptosis
Q41815953Assessment of XAF1 as A Biomarker to Differentiate Hepatocellular Carcinoma from Nonneoplastic Liver Tissues
Q33491820Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer
Q102369464Embryonic periventricular endothelial cells demonstrate a unique pro-neurodevelopment and anti-inflammatory gene signature
Q36129174Epigenetic silencing of the XAF1 gene is mediated by the loss of CTCF binding
Q37302745IAP-targeted therapies for cancer
Q44871312Identification of XAF1-MT2A mutual antagonism as a molecular switch in cell-fate decisions under stressful conditions
Q37626384Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration
Q90425800Paradoxical epigenetic regulation of XAF1 mediates plasticity towards adaptive resistance evolution in MGMT-methylated glioblastoma
Q40226159Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis
Q92177173SARM1 deficiency up-regulates XAF1, promotes neuronal apoptosis, and accelerates prion disease
Q21260407Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta
Q36866484Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death.
Q39750777Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression
Q38943031X-linked inhibitor of apoptosis-associated factor l (XAFl) enhances the sensitivity of colorectal cancer cells to cisplatin
Q34441993XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313
Q34448027XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells
Q58374432XAF1 forms a positive feedback loop with IRF-1 to drive apoptotic stress response and suppress tumorigenesis
Q51993125XAF1 mediates tumor necrosis factor-alpha-induced apoptosis and X-linked inhibitor of apoptosis cleavage by acting through the mitochondrial pathway.
Q36905617XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence

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