Intrapulmonary administration of leukotriene B4 enhances pulmonary host defense against pneumococcal pneumonia (scientific article published on 15 March 2010)

Leukotriene-deficient mice manifest enhanced lethality from Klebsiella pneumonia in association with decreased alveolar macrophage phagocytic and bactericidal activities.

Q52522927

Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia.

Q54017245

Leukotrienes Are Essential for the Control of Leishmania amazonensis Infection and Contribute to Strain Variation in Susceptibility

Q58209914

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

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Leukotriene B4 up-regulates IL-6 rather than IL-1 synthesis in human monocytes

Q68274558

Increased 5-lipoxygenase metabolism in the lungs of human subjects exposed to ozone

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Leukotriene B4 stimulates human polymorphonuclear leukocytes to synthesize and release interleukin-8 in vitro

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Decreased leukotriene B4 synthesis by polymorphonuclear leukocytes from male patients with diabetes mellitus

Q72387435

Endogenous monocyte chemoattractant protein-1 (MCP-1) protects mice in a model of acute septic peritonitis: cross-talk between MCP-1 and leukotriene B4

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The effect of inhaled leukotriene B4 in normal and in asthmatic subjects

Q73346287

Leukotriene B4 receptor antagonism reduces monocytic foam cells in mice

Q77743269

Activation of nitric oxide release and oxidative metabolism by leukotrienes B4, C4, and D4 in human polymorphonuclear leukocytes

Q78015808

Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis

Q80178419

Leukotriene B4 triggers the in vitro and in vivo release of potent antimicrobial agents

Q80428013

Leukotrienes

Q81542824

Lung infection--a public health priority

Q21092388

Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults

Q22242958

Activation and assembly of the NADPH oxidase: a structural perspective

Q28297425

Leukotrienes: underappreciated mediators of innate immune responses

Q28301305

Leukotriene B4 augments neutrophil phagocytosis of Klebsiella pneumoniae

Q28360448

Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase

Q28574027

Bacterial community-acquired pneumonia in older patients

Q30444056

E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection

Q33594642

5-Lipoxygenase reaction products modulate alveolar macrophage phagocytosis of Klebsiella pneumoniae

Q33767333

Role of peroxide in phagocytic killing of pneumococci

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Leukotriene B(4) induces nitric oxide synthesis in Trypanosoma cruzi-infected murine macrophages and mediates resistance to infection

Q34128916

Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability

Q34579474

Leukotrienes are involved in leukocyte recruitment induced by live Histoplasma capsulatum or by the beta-glucan present in their cell wall

Q35041719

Paradoxical role of alveolar macrophage-derived granulocyte-macrophage colony-stimulating factor in pulmonary host defense post-bone marrow transplantation.

Q36808062

Inhibition of leukotriene biosynthesis abrogates the host control of Mycobacterium tuberculosis

Q36967851

Acute lower respiratory tract infection

Q37084070

New immunosuppressive strategies and the risk of infection

Q37277166

Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia.

Q38320187

Impaired leukotriene C4 generation in granulocytes from protein-energy malnourished chronically ill elderly

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Infectious disease hospitalizations in the United States

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Blockade of endogenous leukotrienes exacerbates pulmonary histoplasmosis.

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Cyclophosphamide stimulates lung fibroblasts to release neutrophil and monocyte chemoattractants

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Expression and regulation of chemokines in bacterial pneumonia.

Q40943410

Reduced 5-lipoxygenase metabolism of arachidonic acid in macrophages rrom 1,25-dihydroxyvitamin D3-deficient rats

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Important role for CC chemokine ligand 2-dependent lung mononuclear phagocyte recruitment to inhibit sepsis in mice infected with Streptococcus pneumoniae

Q43779343

Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia

Q43950679

Macrophage Turnover Kinetics in the Lungs of Mice Infected with Streptococcus pneumoniae

Q44015551

Phagocytosis and bactericidal action of mouse peritoneal macrophages treated with leukotriene B4.

Q44028245

Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages

Q45240869

The release of leukotrienes in the respiratory tract during infection with respiratory syncytial virus: role in obstructive airway disease

Q45833536

Leukotriene B4 enhances interleukin-6 (IL-6) production and IL-6 messenger RNA accumulation in human monocytes in vitro: transcriptional and posttranscriptional mechanisms

Q46521770

Leukotriene B4 mediates p47phox phosphorylation and membrane translocation in polyunsaturated fatty acid-stimulated neutrophils.

Q46592208

Specific leukotriene receptors couple to distinct G proteins to effect stimulation of alveolar macrophage host defense functions.

Q46970224

Leukotrienes are potent adjuvant during fungal infection: effects on memory T cells.

Q51960247

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

pneumonia

Q12192

P304

page(s)

2264-2271

P577

publication date

2010-03-15

P1433

published in

Infection and Immunity

Q6029193

P1476

title

Intrapulmonary administration of leukotriene B4 enhances pulmonary host defense against pneumococcal pneumonia

P478

volume

Reverse relations

cites work (P2860)

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P356	DOI	10.1128/IAI.01323-09
P8608	Fatcat ID	release_exwxhrm22jes3exqmiy6txq2dq
P932	PMC publication ID	2863513
P698	PubMed publication ID	20231413
P5875	ResearchGate publication ID	41969065