P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis

scientific article published on 15 December 2005

P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1165/RCMB.2005-0352OC
P932PMC publication ID2644206
P698PubMed publication ID16357363

P2093author name stringDavid W Kamp
Sigmund A Weitzman
Navdeep Chandel
Sailesh Surapureddi
Vijayalakshmi Panduri
Saul Soberanes
P2860cites workMechanisms in the Pathogenesis of Asbestosis and SilicosisQ22299314
P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosisQ71395532
Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestosQ71441112
p53 protein accumulation in lung carcinomas of patients exposed to asbestos and tobacco smokeQ72105420
Mutations, tissue accumulations, and serum levels of p53 in patients with occupational cancers from asbestos and silica exposureQ73786130
Analysis of cell cycle disruptions in cultures of rat pleural mesothelial cells exposed to asbestos fibersQ73966594
Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epitheliumQ74787837
Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosisQ81281274
Essential role of p53 in silica-induced apoptosisQ23917077
The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activationQ23923194
Crocidolite induces cell transformation and p53 gene mutation in BALB/c-3T3 cellsQ24169605
Phosphorylation of p53 protein in A549 human pulmonary epithelial cells exposed to asbestos fibersQ24814258
Facile detection of mitochondrial DNA mutations in tumors and bodily fluidsQ28138849
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and deathQ28363890
The molecular basis of asbestos induced lung injuryQ28394122
ATM and related protein kinases: safeguarding genome integrityQ29547735
The pathophysiology of mitochondrial cell deathQ29547893
Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosisQ31153442
Redox regulation of p53 during hypoxiaQ31431060
An overview of real-time quantitative PCR: applications to quantify cytokine gene expressionQ34532446
p53, Cip1, and Gadd153 expression following treatment of A549 cells with natural and man-made vitreous fibersQ34639501
Decision making by p53: life, death and cancerQ35116663
Checking on DNA damage in S phaseQ35906070
Transcription, apoptosis and p53: catch-22.Q36056198
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosisQ36399732
Influence of induced reactive oxygen species in p53-mediated cell fate decisions.Q37061407
Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen speciesQ37361129
Redox modulation of p53 conformation and sequence-specific DNA binding in vitro.Q38315428
Ethnicity and skin test reactivity to aeroallergens among asthmatic children in ConnecticutQ39673609
A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosisQ40019792
Mitochondrial-derived free radicals mediate asbestos-induced alveolar epithelial cell apoptosisQ40591784
The mitochondria-regulated death pathway mediates asbestos-induced alveolar epithelial cell apoptosisQ40675656
Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53.Q40685205
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapyQ40929887
Abrogation of the G2 checkpoint results in differential radiosensitization of G1 checkpoint-deficient and G1 checkpoint-competent cellsQ41350125
Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicalsQ41362043
Phagocytosis of crocidolite asbestos induces oxidative stress, DNA damage, and apoptosis in mesothelial cellsQ41759277
Inhaled asbestos fibers induce p53 expression in the rat lungQ42437265
Asbestos causes apoptosis in alveolar epithelial cells: role of iron-induced free radicalsQ43592789
Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.Q43847020
p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.Q44362161
Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosisQ44572455
Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53.Q44749119
Cell type-specific effects of asbestos on intracellular ROS levels, DNA oxidation and G1 cell cycle checkpointQ45103592
p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondriaQ47314815
Crocidolite asbestos causes an induction of p53 and apoptosis in cultured A-549 lung carcinoma cellsQ47349733
Development of lung tumors in mutant p53-expressing mice after inhalation exposure to asbestosQ47622851
Enhancement of fibrogenesis by the p53 tumor suppressor protein in asbestos-exposed rodentsQ49164232
Iron Mobilization from Crocidolite Asbestos by Human Lung Carcinoma CellsQ58821454
Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxideQ70189326
P433issue4
P921main subjectasbestosQ104085
P304page(s)443-452
P577publication date2005-12-15
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleP53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis
P478volume34