Heparanase Mediates Intestinal Inflammation and Injury in a Mouse Model of Sepsis

scientific article published on January 2017

Heparanase Mediates Intestinal Inflammation and Injury in a Mouse Model of Sepsis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1369/0022155417692536
P932PMC publication ID5407566
P698PubMed publication ID28170292

P2093author name stringYing He
Guiyun Jin
Song Chen
Xiaochun Ma
Xiaohan Yin
Siyu Lu
Ziwei Hu
Chuanzhu Lv
P2860cites workMammalian heparanase: gene cloning, expression and function in tumor progression and metastasisQ22010222
Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin speciesQ28285451
Heparan sulphate proteoglycans fine-tune mammalian physiologyQ29619329
Guide to anticoagulant therapy: Heparin : a statement for healthcare professionals from the American Heart AssociationQ33337780
Versatile role of heparanase in inflammationQ33770777
Mammalian heparanase: what is the message?Q34652072
Roles of heparan-sulphate glycosaminoglycans in cancerQ34718195
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in miceQ34876266
Syndecans in inflammationQ35094731
Heparan Sulfate Core Proteins in Cell-Cell SignalingQ35582990
High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpressionQ35695593
The Synthetic Antimicrobial Peptide 19-2.5 Interacts with Heparanase and Heparan Sulfate in Murine and Human SepsisQ35850606
Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanaseQ35853992
Intestinal crosstalk: a new paradigm for understanding the gut as the "motor" of critical illnessQ36157201
Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammationQ36361058
Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myelomaQ36499443
Proteoglycans in cancer biology, tumour microenvironment and angiogenesisQ36787608
The anti-inflammatory effects of heparin and related compoundsQ36922642
Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myelomaQ36973696
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.Q37045970
Heparanase mediates renal dysfunction during early sepsis in mice.Q37411095
The role of innate signaling in the homeostasis of tolerance and immunity in the intestine.Q37604052
Low-dose low-molecular weight heparin (enoxaparin) is effective as adjuvant treatment in active ulcerative colitis: an open trialQ43779548
Treatment with unfractionated heparin attenuates coagulation and inflammation in endotoxemic mice.Q53225041
Syndecan-1 and heparanase: potential markers for activity evaluation and differential diagnosis of Crohn's disease.Q54267579
Cutting edge: an endogenous pathway to systemic inflammatory response syndrome (SIRS)-like reactions through Toll-like receptor 4Q75197360
Unfractioned heparin in the therapy of patients with highly active inflammatory bowel diseaseQ77861798
Heparanase upregulation by colonic epithelium in inflammatory bowel diseaseQ79241944
Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasisQ79906000
P433issue4
P921main subjectsepsisQ183134
P304page(s)241-249
P577publication date2017-02-07
P1433published inJournal of Histochemistry and CytochemistryQ1523992
P1476titleHeparanase Mediates Intestinal Inflammation and Injury in a Mouse Model of Sepsis
P478volume65

Reverse relations

cites work (P2860)
Q89495589Both UFH and NAH alleviate shedding of endothelial glycocalyx and coagulopathy in LPS-induced sepsis
Q92369060Modulation of Intestinal Epithelial Glycocalyx Development by Human Milk Oligosaccharides and Non-Digestible Carbohydrates
Q46305715Regulation and function of endothelial glycocalyx layer in vascular diseases
Q52725487Syndecan-1 shedding inhibition to protect against ischemic acute kidney injury through HGF target signaling pathway.
Q47207922The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies.
Q59340175Unfractionated heparin ameliorates pulmonary microvascular endothelial barrier dysfunction via microtubule stabilization in acute lung injury

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