| scholarly article | Q13442814 |
| P356 | DOI | 10.1021/JP210579B |
| P8608 | Fatcat ID | release_vobh2g4amzh3ldkl635jhfmtdm |
| P932 | PMC publication ID | 3257414 |
| P698 | PubMed publication ID | 22185605 |
| P5875 | ResearchGate publication ID | 51903698 |
| P2093 | author name string | Chang-Guo Zhan | |
| Guangrong Zheng | |||
| Xiaoqin Huang | |||
| P2860 | cites work | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice | Q24286950 |
| Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes | Q24297806 | ||
| Amino acid substitution matrices from protein blocks | Q24563220 | ||
| Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists | Q24619974 | ||
| The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist | Q24654563 | ||
| High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor | Q24657484 | ||
| Crystal structure of rhodopsin: A G protein-coupled receptor | Q27625972 | ||
| Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor | Q27646733 | ||
| Crystal structure of the human beta2 adrenergic G-protein-coupled receptor | Q27648868 | ||
| A Specific Cholesterol Binding Site Is Established by the 2.8 Å Structure of the Human β2-Adrenergic Receptor | Q27650801 | ||
| Structure of a beta1-adrenergic G-protein-coupled receptor | Q27651011 | ||
| VMD: visual molecular dynamics | Q27860554 | ||
| Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins | Q28244789 | ||
| M5 muscarinic receptors are required for prolonged accumbal dopamine release after electrical stimulation of the pons in mice | Q28592090 | ||
| Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models | Q29616389 | ||
| Reduced surface: an efficient way to compute molecular surfaces | Q29617526 | ||
| Muscarinic receptor ligands and their therapeutic potential | Q33695764 | ||
| AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release | Q34076241 | ||
| M5 muscarinic receptors are needed for slow activation of dopamine neurons and for rewarding brain stimulation | Q34273834 | ||
| Use of M1-M5 muscarinic receptor knockout mice as novel tools to delineate the physiological roles of the muscarinic cholinergic system | Q35098516 | ||
| Fundamental reaction pathway and free energy profile for hydrolysis of intracellular second messenger adenosine 3',5'-cyclic monophosphate (cAMP) catalyzed by phosphodiesterase-4. | Q35532041 | ||
| Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors | Q37208884 | ||
| In vivo and in vitro pharmacological characterization of SVT-40776, a novel M3 muscarinic receptor antagonist, for the treatment of overactive bladder. | Q37230811 | ||
| Topology of class A G protein-coupled receptors: insights gained from crystal structures of rhodopsins, adrenergic and adenosine receptors | Q37306269 | ||
| The M5 muscarinic receptor as possible target for treatment of drug abuse | Q37696541 | ||
| The crystallographic structure of the human adenosine A2A receptor in a high-affinity antagonist-bound state: implications for GPCR drug screening and design | Q37764224 | ||
| Progress in structure based drug design for G protein-coupled receptors | Q37880053 | ||
| Mechanism for cocaine blocking the transport of dopamine: insights from molecular modeling and dynamics simulations | Q39938422 | ||
| Modeling the catalysis of anti-cocaine catalytic antibody: competing reaction pathways and free energy barriers | Q40113750 | ||
| Characterization of the structures of phosphodiesterase 10 binding with adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate by hybrid quantum mechanical/molecular mechanical calculations | Q40817937 | ||
| Catalytic mechanism of cytochrome P450 for 5'-hydroxylation of nicotine: fundamental reaction pathways and stereoselectivity. | Q41836815 | ||
| Loss of M5 muscarinic acetylcholine receptors leads to cerebrovascular and neuronal abnormalities and cognitive deficits in mice. | Q42500981 | ||
| Muscarinic receptor antagonist therapy improves acute pulmonary dysfunction after smoke inhalation injury in sheep | Q42908605 | ||
| Preclinical evaluation of long-acting muscarinic antagonists: comparison of tiotropium and investigational drugs. | Q45991777 | ||
| M5 muscarinic receptor knockout mice show reduced morphine-induced locomotion but increased locomotion after cholinergic antagonism in the ventral tegmental area | Q46320304 | ||
| Large-scale validation of a quantum mechanics based scoring function: predicting the binding affinity and the binding mode of a diverse set of protein-ligand complexes | Q46586108 | ||
| The predicted 3D structures of the human M1 muscarinic acetylcholine receptor with agonist or antagonist bound | Q46629126 | ||
| Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M(3) muscarinic acetylcholine receptor | Q46644237 | ||
| Crystallizing thinking about the beta2-adrenergic receptor. | Q46779816 | ||
| Docking analyses on human muscarinic receptors: unveiling the subtypes peculiarities in agonists binding | Q46817465 | ||
| Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents. | Q51800873 | ||
| The electrostatic potential of B-DNA. | Q52425498 | ||
| The role of charge interactions in muscarinic agonist binding, and receptor-response coupling. | Q54494926 | ||
| Muscarinic receptors: A comparative analysis of structural features and binding modes through homology modelling and molecular docking | Q56899096 | ||
| Critical Role for the Second Extracellular Loop in the Binding of Both Orthosteric and Allosteric G Protein-coupled Receptor Ligands | Q57838214 | ||
| Design and synthesis of a fluorescent muscarinic antagonist | Q58293439 | ||
| A network of conserved intramolecular contacts defines the off-state of the transmembrane switch mechanism in a seven-transmembrane receptor | Q73462978 | ||
| Combination of the CHARMM27 force field with united-atom lipid force fields | Q83676992 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 532-541 | |
| P577 | publication date | 2011-12-20 | |
| P1433 | published in | Journal of Physical Chemistry B | Q668669 |
| P1476 | title | Microscopic binding of M5 muscarinic acetylcholine receptor with antagonists by homology modeling, molecular docking, and molecular dynamics simulation | |
| P478 | volume | 116 |
| Q28082151 | Mathematical and computational modeling in biology at multiple scales |
| Q92946309 | Metabolites of Vinca Alkaloid Vinblastine: Tubulin Binding and Activation of Nausea-Associated Receptors |
| Q36037754 | Modeling and Re-Engineering of Azotobacter vinelandii Alginate Lyase to Enhance Its Catalytic Efficiency for Accelerating Biofilm Degradation |
| Q40487987 | Molecular modeling and redesign of alginate lyase from Pseudomonas aeruginosa for accelerating CRPA biofilm degradation |
| Q36912560 | Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists |
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