Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein (scientific article published on 29 August 2005)

Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation

Q24537588

HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs

Q24797317

C-terminal domain phosphatase sensitivity of RNA polymerase II in early elongation complexes on the HIV-1 and adenovirus 2 major late templates

Q28143301

Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones

Q28143943

Nuclear protein phosphatase-1 regulates HIV-1 transcription

Q28177130

A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat

Q28201367

Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II

Q28218480

Direct interaction of human TFIID with the HIV-1 transactivator tat

Q28250314

Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production

Q28256684

Structural basis of protein phosphatase 1 regulation

Q28263645

Regulation of carboxyl-terminal domain phosphatase by HIV-1 tat protein

Q28289216

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

Q28306995

Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain

Q28343959

TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

Q28647556

Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

Q29614788

Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.

Q34149144

Protein phosphatase 2A enhances activation of human immunodeficiency virus type 1 by phorbol myristate acetate

Q34467506

Signaling by protein phosphatases in the nucleus

Q34540906

Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy

Q34714816

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

Q35964369

HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription

Q40727461

On the role of the second coding exon of the HIV-1 Tat protein in virus replication and MHC class I downregulation

Q40990486

The gamma134.5 protein of herpes simplex virus 1 has the structural and functional attributes of a protein phosphatase 1 regulatory subunit and is present in a high molecular weight complex with the enzyme in infected cells

Q41018806

HIV-1 tat transcriptional activity is regulated by acetylation

Q42163503

HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter

Q44061963

Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1.

Q44376511

Interactor-mediated nuclear translocation and retention of protein phosphatase-1.

Q45121906

Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.

Q46675052

Preparation of low-molecular-weight forms of rabbit muscle protein phosphatase

Q47187783

P433

issue

P407

language of work or name

English

Q1860

P304

page(s)

36364-36371

P577

publication date

2005-08-29

P1433

published in

Journal of Biological Chemistry

Q867727

P1476

title

Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein

P478

volume

280

Reverse relations

cites work (P2860)

Q34619456	1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription
Q40760981	2C Proteins of Enteroviruses Suppress IKKβ Phosphorylation by Recruiting Protein Phosphatase 1
Q40195173	A novel anticancer agent ARC antagonizes HIV-1 and HCV.
Q35912884	Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound.
Q28276848	Cracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFb
Q37645582	Curing HIV: Pharmacologic approaches to target HIV-1 latency
Q90683506	Diversity of small molecule HIV-1 latency reversing agents identified in low- and high-throughput small molecule screens
Q37075889	Enforcing the pause: transcription factor Sp3 limits productive elongation by RNA polymerase II.
Q34537015	Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription
Q21245051	In vitro nuclear interactome of the HIV-1 Tat protein
Q42951594	Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03.
Q38329033	Inhibition of PP1 phosphatase activity by HBx: a mechanism for the activation of hepatitis B virus transcription
Q64912294	Interaction of Structural Glycoprotein E2 of Classical Swine Fever Virus with Protein Phosphatase 1 Catalytic Subunit Beta (PPP1CB).
Q36143645	Iron chelators ICL670 and 311 inhibit HIV-1 transcription
Q36274198	MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding
Q40055940	Miklós Bodanszky Award Lecture: Advances in the selective targeting of protein phosphatase-1 and phosphatase-2A with peptides
Q57282212	Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Therapeutics
Q34919381	New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC).
Q34481984	Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus
Q35131134	Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription
Q42006129	Positive feedback loop mediated by protein phosphatase 1α mobilization of P-TEFb and basal CDK1 drives androgen receptor in prostate cancer
Q38662748	Protein Phosphatase-1 -targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals
Q37539350	Protein Phosphatase-1 Regulates Expression of Neuregulin-1.
Q33886004	Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175.
Q35856911	Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1.
Q37553804	Regulation of CDK9 activity by phosphorylation and dephosphorylation.
Q38430337	Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription
Q34044597	Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription
Q28286819	Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions
Q28480912	Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1
Q90401053	Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition
Q39609732	Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.
Q37958430	The control of HIV transcription: keeping RNA polymerase II on track
Q34219706	The ins and outs of HIV-1 Tat.
Q37834642	The phosphoprotein phosphatase family of Ser/Thr phosphatases as principal targets of naturally occurring toxins
Q36895615	Transcriptional and post-transcriptional regulation of HIV-1 gene expression: role of cellular factors for Tat and Rev.
Q24317732	Tyrosine phosphorylation controls PCNA function through protein stability
Q35026881	Viral-host interactions that control HIV-1 transcriptional elongation