Mechanisms of action of currently prescribed and newly developed antiepileptic drugs

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Mechanisms of action of currently prescribed and newly developed antiepileptic drugs is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1111/J.1528-1157.1994.TB05955.X
P698PubMed publication ID7513639
P5875ResearchGate publication ID227656785

P2093author name stringR L Macdonald
K M Kelly
P2860cites workImportance of a novel GABAA receptor subunit for benzodiazepine pharmacologyQ24306621
Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retinaQ24314636
Structure and functional expression of alpha 1, alpha 2, and beta subunits of a novel human neuronal calcium channel subtypeQ24324250
3HPropyl ?-Carboline-3-Carboxylate as a Selective Radioligand for the BZ1Benzodiazepine Receptor SubclassQ53945882
Diazepam and (--)-pentobarbital: fluctuation analysis reveals different mechanisms for potentiation of gamma-aminobutyric acid responses in cultured central neuronsQ24616501
Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reductionQ24673531
Structure and functional expression of a member of the low voltage-activated calcium channel familyQ28263366
Interaction of felbamate and diazepam against maximal electroshock seizures and chemoconvulsants in miceQ28322207
Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbitalQ28339879
Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neuronsQ28342691
Type I and type II GABAA-benzodiazepine receptors produced in transfected cellsQ28342945
Two novel GABAA receptor subunits exist in distinct neuronal subpopulationsQ28565909
Molecular cloning of multiple subtypes of a novel rat brain isoform of the α1 subunit of the voltage-dependent calcium channelQ33234346
Rat brain expresses a heterogeneous family of calcium channels.Q33561306
Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology.Q33902225
Specific petit mal anticonvulsants reduce calcium currents in thalamic neuronsQ34523168
Primary structure and functional expression from complementary DNA of a brain calcium channelQ34779902
Multiple benzodiazepine receptors: no reason for anxietyQ35227013
Primary structure of a calcium channel that is highly expressed in the rat cerebellumQ37539944
Structure and function of voltage-sensitive ion channelsQ38193558
The biochemistry and molecular biology of the dihydropyridine-sensitive calcium channelQ38201288
Cloning, pharmacological characteristics and expression pattern of the rat GABAA receptor alpha 4 subunitQ38333425
GABAA receptor channelsQ40389943
Postnatal development of proteins associated with different benzodiazepine receptors.Q41363612
Cloned GABA receptors are maintained in a stable cell line: allosteric and channel propertiesQ41727572
Functional properties of recombinant rat GABAA receptors depend upon subunit compositionQ41733452
Primary structure and functional expression of the omega-conotoxin-sensitive N-type calcium channel from rabbit brainQ42616215
Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in cultureQ43652740
Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in cultureQ44750625
Resolution of two biochemically and pharmacologically distinct benzodiazepine receptorsQ45157485
A neuropharmacological evaluation of felbamate as a novel anticonvulsantQ45762537
Distinct calcium channels are generated by alternative splicing and are differentially expressed in the mammalian CNSQ48220991
Photoaffinity labeling of benzodiazepine receptor proteins with the partial inverse agonist [3H]Ro 15-4513: a biochemical and autoradiographic studyQ48254491
Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studiesQ48332179
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studiesQ48332188
Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-familyQ48341437
Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentinQ48369138
An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channelsQ48416270
P-type calcium channels in rat central and peripheral neuronsQ48465981
The development of type I and type II benzodiazepine receptors in the mouse cortex and cerebellumQ48485962
Gabapentin increases aminooxyacetic acid-induced GABA accumulation in several regions of rat brainQ48687083
Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?Q48723504
Comparison of gabapentin with other antiepileptic and GABAergic drugsQ48756931
Effects of chlordiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam and haloperidol on the voltage-dependent sodium current of isolated mammalian brain neurons.Q51750209
Three types of neuronal calcium channel with different calcium agonist sensitivity.Q51824457
Calcium currents in rat thalamocortical relay neurones: kinetic properties of the transient, low-threshold current.Q52425365
P407language of work or nameEnglishQ1860
P304page(s)S41-50
P577publication date1994-01-01
P1433published inEpilepsiaQ5382969
P1476titleMechanisms of action of currently prescribed and newly developed antiepileptic drugs
P478volume35 Suppl 4

Reverse relations

cites work (P2860)
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