Primary structure and functional expression from complementary DNA of a brain calcium channel

scientific article published on April 4, 1991

Primary structure and functional expression from complementary DNA of a brain calcium channel is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1006712595
P356DOI10.1038/350398A0
P953full work available at URLhttp://www.nature.com/articles/350398a0
http://www.nature.com/articles/350398a0.pdf
P698PubMed publication ID1849233

P50authorTeiichi FuruichiQ88781060
P2093author name stringFlockerzi V
Kim MS
Mori Y
Hofmann F
Friedrich T
Mikami A
Nakai J
Ruth P
Bosse E
P2860cites workPrimary structure of the receptor for calcium channel blockers from skeletal muscleQ28288569
Phosphorylation-Dephosphorylation of EnzymesQ28306047
Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poisonQ29029753
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybridsQ29618273
The fine structure of staggerer cerebellumQ31027136
Funnel-web spider venom and a toxin fraction block calcium current expressed from rat brain mRNA in Xenopus oocytesQ33632581
Electrophysiological properties of in vitro Purkinje cell dendrites in mammalian cerebellar slicesQ34287560
Molecular distinction between fetal and adult forms of muscle acetylcholine receptorQ34385501
Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channelQ34407794
Restoration of excitation-contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA.Q34560693
Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscleQ34633282
Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channelQ34661325
Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.Q35534135
Purkinje cell degeneration, a new neurological mutation in the mouseQ35982103
The biochemistry and molecular biology of the dihydropyridine-sensitive calcium channelQ38201288
Multiple types of neuronal calcium channels and their selective modulationQ38201289
Long-term depressionQ38613310
The Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of Weaver and Staggerer miceQ39474490
Structural requirements of N-glycosylation of proteins. Studies with proline peptides as conformational probesQ42140913
Induction of calcium currents by the expression of the alpha 1-subunit of the dihydropyridine receptor from skeletal muscleQ43742103
Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant miceQ43917459
Action of organic antagonists on neuronal calcium currentsQ44541107
Primary structure and functional expression of a high voltage activated calcium channel from rabbit lungQ44697610
The cDNA and deduced amino acid sequence of the gamma subunit of the L-type calcium channel from rabbit skeletal muscleQ46842109
Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscleQ48287511
Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytesQ48366976
Subunit structure and localization of dihydropyridine-sensitive calcium channels in mammalian brain, spinal cord, and retinaQ48961069
Selective absence of calcium spikes in Purkinje cells of staggerer mutant mice in cerebellar slices maintained in vitro.Q54481520
Structural parts involved in activation and inactivation of the sodium channelQ59072056
Cardiac-type excitation-contraction coupling in dysgenic skeletal muscle injected with cardiac dihydropyridine receptor cDNAQ59095343
Molecular structure of sodium channelsQ68984672
Presynaptic Ca-antagonist omega-conotoxin irreversibly blocks N-type Ca-channels in chick sensory neuronsQ68992506
P433issue6317
P407language of work or nameEnglishQ1860
P921main subjectcalciumQ706
complementary DNAQ283478
P304page(s)398-402
P577publication date1991-04-01
1991-04-04
P1433published inNatureQ180445
P1476titlePrimary structure and functional expression from complementary DNA of a brain calcium channel
P478volume350

Reverse relations

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Q35048422Identification of R(-)-isomer of efonidipine as a selective blocker of T-type Ca2+ channels
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Q46465452Identification of a second region of the beta-subunit involved in regulation of calcium channel inactivation
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Q40970956Identification of an integration center for cross-talk between protein kinase C and G protein modulation of N-type calcium channels
Q49019394Identification of critical amino acids involved in alpha1-beta interaction in voltage-dependent Ca2+ channels
Q41633172Identifying neuronal non-L Ca2+ channels--more than stamp collecting?
Q72054896Immunochemical Identification and Differential Phosphorylation of Alternatively Spliced Forms of the α1A Subunit of Brain Calcium Channels
Q47750692Immunocytochemical localization of the alpha 1A subunit of the P/Q-type calcium channel in the rat cerebellum
Q40371886Immunopathology of the Lambert-Eaton myasthenic syndrome
Q28504514Impaired feedforward inhibition of the thalamocortical projection in epileptic Ca2+ channel mutant mice, tottering
Q48737226Importance of the different beta subunits in the membrane expression of the alpha1A and alpha2 calcium channel subunits: studies using a depolarization-sensitive alpha1A antibody
Q35026285Inhibition of Ca2+ channel current by mu- and kappa-opioid receptors coexpressed in Xenopus oocytes: desensitization dependence on Ca2+ channel alpha 1 subunits
Q48921080Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin
Q30468053Inhibition of calcium currents and exocytosis by Lambert-Eaton syndrome antibodies in human lung cancer cells
Q48637663Inhibitory effects of a new neuroprotective diltiazem analogue, T-477, on cloned brain Ca2+ channels expressed in Xenopus oocytes
Q48084989Insect calcium channels. Molecular cloning of an alpha 1-subunit from housefly (Musca domestica) muscle
Q40877344Insertion of the full-length calcium channel alpha(1S) subunit into triads of skeletal muscle in vitro.
Q45927129Interaction between Ca(v)2.1alpha (1) and CaMKII in Ca (v)2.1alpha (1) mutant mice, Rolling Nagoya.
Q49053546Interaction of SNARE complexes with P/Q-type calcium channels in rat cerebellar synaptosomes
Q33691495Interactions of presynaptic Ca2+ channels and snare proteins in neurotransmitter release
Q40675683Interrelationships of cyclic GMP, inositol phosphates, and calcium.
Q73039701Intracellular Ca(2+) channel immunoreactivity in neuroendocrine axon terminals
Q34311621Ion channel associated diseases: overview of molecular mechanisms
Q24309661Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25
Q30495677KCa channels as therapeutic targets in episodic ataxia type-2
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Q33602333L-type calcium channel modulation.
Q33843210Lambert-Eaton myasthenic syndrome as an autoimmune calcium-channelopathy
Q48262699Large Ca²⁺-dependent facilitation of Ca(V)2.1 channels revealed by Ca²⁺ photo-uncaging
Q44887923Linear B-cell epitopes in Lambert-Eaton myasthenic syndrome defined by cell-free synthetic peptide binding
Q35863195Localization and functional properties of a rat brain alpha 1A calcium channel reflect similarities to neuronal Q- and P-type channels
Q47710312Localization of Ca2+ channel subtypes on rat spinal motor neurons, interneurons, and nerve terminals.
Q37576584Localization of P-type calcium channels in the central nervous system
Q71873748Localization of mRNAs of voltage-dependent Ca2+-channels: four subtypes of α1- and β-subunits in developing and mature rat brain
Q44151250Long-term regulation of voltage-gated Ca(2+) channels by gabapentin
Q34114755Low single channel conductance of the major skeletal muscle chloride channel, ClC-1.
Q39426378Low-affinity blockade of neuronal N-type Ca channels by the spider toxin omega-agatoxin-IVA.
Q36852280Mechanism of auxiliary subunit modulation of neuronal alpha1E calcium channels
Q43559720Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.
Q44147514Mechanism of down-regulation of L-type Ca(2+) channel in the proliferating smooth muscle cells of rat aorta
Q42037709Mechanism of voltage- and use-dependent block of class A Ca2+ channels by mibefradil
Q40388644Mechanisms of action of currently prescribed and newly developed antiepileptic drugs
Q48853806Modelling of the III-IV loop, a domain involved in calcium channel Ca(v)2.1 inactivation, highlights a structural homology with the gamma subunit of G proteins.
Q35682306Modulation and pharmacology of low voltage-activated ("T-Type") calcium channels
Q48450854Modulation of Ca2+ channel currents of acutely dissociated rat periaqueductal grey neurons
Q56568483Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
Q44636399Modulation of cardiac Ca2+ channels in Xenopus oocytes by protein kinase C.
Q40932854Modulation of neuronal voltage-gated calcium channels by farnesol.
Q42633914Modulation of slow inactivation in class A Ca2+ channels by beta-subunits
Q50760517Modulation of the alpha 1A Ca2+ channel by beta subunits at physiological Ca2+ concentration.
Q55026191Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal.
Q40856034Molecular and biophysical view of the Ca channel: a hypothesis regarding oligomeric structure, channel clustering, and macroscopic current.
Q33691491Molecular and functional diversity of voltage-gated calcium channels
Q41460029Molecular aspects of ion permeation through channels
Q36513343Molecular basis of inherited calcium channelopathies: role of mutations in pore-forming subunits
Q40950178Molecular biology of calcium channels
Q37283190Molecular characterization and nephron distribution of a family of transcripts encoding the pore-forming subunit of Ca2+ channels in the kidney
Q46181507Molecular cloning and characterization of a novel calcium channel from rabbit brain
Q31916649Molecular cloning of a putative cyclic nucleotide-gated ion channel cDNA from Limulus polyphemus
Q37042524Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel
Q40532102Molecular determinants of Ca2+ channel function and drug action
Q59053918Molecular determinants of voltage-dependent inactivation in calcium channels
Q41735746Molecular diversity in neurosecretion: reflections on the hypothalamo-neurohypophysial system
Q36264291Molecular diversity of Ca2+ channel alpha 1 subunits from the marine ray Discopyge ommata
Q24561719Molecular diversity of L-type Ca2+ channel transcripts in human fibroblasts
Q41592490Molecular diversity of neuronal-type calcium channels identified in small cell lung carcinoma
Q41460062Molecular diversity of voltage-dependent calcium channel
Q28359643Molecular interaction of dihydropyridine receptors with type-1 ryanodine receptors in rat brain
Q37472670Molecular mechanism of active zone organization at vertebrate neuromuscular junctions
Q36726660Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: role of inactivation
Q36774733Molecular pathogenesis of spinocerebellar ataxia type 6.
Q74261868Molecular pharmacology of UK-118, 434-05, a permanently charged amlodipine analog
Q34303106Molecular pharmacology of high voltage-activated calcium channels
Q48265829Molecular properties of calcium channels in skeletal muscle and neurons
Q28302396Molecular structures involved in L-type calcium channel inactivation. Role of the carboxyl-terminal region encoded by exons 40-42 in alpha1C subunit in the kinetics and Ca2+ dependence of inactivation
Q48952010Molecular studies on the voltage dependence of dihydropyridine action on L-type Ca2+ channels. Critical involvement of tyrosine residues in motif IIIS6 and IVS6.
Q41132465Motif III S5 of L-type calcium channels is involved in the dihydropyridine binding site. A combined radioligand binding and electrophysiological study
Q32052826Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit
Q48148450Multiple structural domains contribute to voltage-dependent inactivation of rat brain alpha(1E) calcium channels
Q61981684Mutations in the Cacnl1a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice
Q34250181Mutations in the alpha1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegans
Q31160146Mutually exclusive exon splicing of the cardiac calcium channel alpha 1 subunit gene generates developmentally regulated isoforms in the rat heart
Q48637379N-Type calcium channels in the developing rat hippocampus: subunit, complex, and regional expression.
Q50794466Native-type DHP-sensitive calcium channel currents are produced by cloned rat aortic smooth muscle and cardiac alpha 1 subunits expressed in Xenopus laevis oocytes and are regulated by alpha 2- and beta-subunits.
Q73342041Neuron-specific expression of reporter gene in transgenic mice carrying the 5'-upstream region of mouse P/Q-type Ca2+ channel alpha 1A subunit gene fused to E. coli lacZ reporter gene
Q38322644Neuronal voltage-activated calcium channels: on the roles of the alpha 1E and beta 3 subunits.
Q34406472New ataxic tottering-6j mouse allele containing a Cacna1a gene mutation
Q36706644Next-generation sequencing identifies novel CACNA1A gene mutations in episodic ataxia type 2
Q40879522Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188.
Q34171721Nonglutamate pore residues in ion selection and conduction in voltage-gated Ca2+ channels
Q28585263Novel Cav2.1 splice variants isolated from Purkinje cells do not generate P-type Ca2+ current
Q35676370Novel splice variants of rat CaV2.1 that lack much of the synaptic protein interaction site are expressed in neuroendocrine cells
Q37218136Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels
Q48933475Ocular motor measures in migraine with and without aura
Q21144219Orientation of the calcium channel beta relative to the alpha(1)2.2 subunit is critical for its regulation of channel activity
Q36412553Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation
Q48933673Oxidation regulates cloned neuronal voltage-dependent Ca2+ channels expressed in Xenopus oocytes.
Q48525988P-type calcium channels blocked by the spider toxin ω-Aga-IVA
Q45934932P/Q-type Ca2+ channel defects in migraine, ataxia and epilepsy.
Q43825288PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats
Q28216827Pain perception in mice lacking the beta3 subunit of voltage-activated calcium channels
Q36464816Performances in cerebellar and neuromuscular transmission tests are correlated in migraine with aura
Q71437930Periodic paralysis and voltage-gated ion channels
Q48754094Pharmacological characterisation of voltage-sensitive calcium channels and neurotransmitter release from mouse cerebellar granule cells in culture
Q30807531Phoneutria nigriventer omega-phonetoxin IIA blocks the Cav2 family of calcium channels and interacts with omega-conotoxin-binding sites
Q40788634Phosphorylation of presynaptic and postsynaptic calcium channels by cAMP-dependent protein kinase in hippocampal neurons
Q48630147Phosphorylation of the synaptic protein interaction site on N-type calcium channels inhibits interactions with SNARE proteins
Q48519130Physical and functional interaction of the active zone protein CAST/ERC2 and the β-subunit of the voltage-dependent Ca(2+) channel
Q48382848Physical link and functional coupling of presynaptic calcium channels and the synaptic vesicle docking/fusion machinery
Q48115181Possible modulatory role of voltage-activated Ca(2+) currents determining the membrane properties of isolated pyramidal neurones of the rat dorsal cochlear nucleus
Q36445185Potentiation of the cardiac L-type Ca(2+) channel (alpha(1C)) by dihydropyridine agonist and strong depolarization occur via distinct mechanisms
Q48627074Presynaptic calcium channels and field-evoked transmitter exocytosis from cultured cerebellar granule cells.
Q90246164Presynaptic calcium channels: specialized control of synaptic neurotransmitter release
Q48087322Primary structure and tissue distribution of a novel calcium channel from rabbit brain
Q24677069Progressive ataxia due to a missense mutation in a calcium-channel gene
Q48129075Properties of Q-type calcium channels in neostriatal and cortical neurons are correlated with beta subunit expression.
Q41118042Properties of cloned rat alpha1A calcium channels transiently expressed in the COS-7 cell line
Q37388710Proteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels
Q37640933Purified omega-conotoxin GVIA receptor of rat brain resembles a dihydropyridine-sensitive L-type calcium channel
Q41467706Quantification of two splicing events in the L-type calcium channel alpha-1 subunit of intestinal smooth muscle and other tissues
Q41770497RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels.
Q28572143Rab3-interacting molecule gamma isoforms lacking the Rab3-binding domain induce long lasting currents but block neurotransmitter vesicle anchoring in voltage-dependent P/Q-type Ca2+ channels
Q30982932Rat brain expresses an alternatively spliced form of the dihydropyridine-sensitive L-type calcium channel alpha 2 subunit
Q33648520Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons
Q73094523Reciprocal regulation of P/Q-type Ca2+ channels by SNAP-25, syntaxin and synaptotagmin
Q24540027Recurrence of the T666M calcium channel CACNA1A gene mutation in familial hemiplegic migraine with progressive cerebellar ataxia
Q28510118Reduced voltage sensitivity of activation of P/Q-type Ca2+ channels is associated with the ataxic mouse mutation rolling Nagoya (tg(rol))
Q48799434Regional expression and cellular localization of the alpha1 and beta subunit of high voltage-activated calcium channels in rat brain.
Q48332899Regulation by protein kinase-C of putative P-type Ca channels expressed in Xenopus oocytes from cerebellar mRNA.
Q33763700Regulation of high-voltage-activated Ca(2+) channel function, trafficking, and membrane stability by auxiliary subunits
Q36295788Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).
Q38358447Regulation of the TRP Ca2+ channel by INAD in Drosophila photoreceptors
Q44840046Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel inactivation
Q70494325Requirement of the calcium channel beta subunit for functional conformation
Q54255293Re‐evaluation of calcium currents in pre‐ and postsynaptic neurones of the chick ciliary ganglion
Q33915557Role of S4 segments and the leucine heptad motif in the activation of an L-type calcium channel
Q74481409SCA6 mutation analysis in a large cohort of the Japanese patients with late-onset pure cerebellar ataxia
Q43972718Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons.
Q61918639Sequence Differences between α1Cand α1SCa2+Channel Subunits Reveal Structural Determinants of a Guarded and Modulated Benzothiazepine Receptor
Q46735565Sequences of cDNAs encoding calmodulin, and partial structures of calmodulin kinase, and a calcium channel of kdr-resistant and -susceptible German cockroaches, Blattella germanica
Q36264191Signal transduction in endocrine tissues
Q28510345Single tottering mutations responsible for the neuropathic phenotype of the P-type calcium channel
Q37980111Smithkline Beecham Prize for Young Psychopharmacologists: A review of the relationship between calcium channels and psychiatric disorders
Q48070915Sodium channel functioning based on an octagonal structure model
Q27639461Solution structure of omega-grammotoxin SIA, a gating modifier of P/Q and N-type Ca(2+) channel
Q39096400Spinal dorsal horn calcium channel alpha2delta-1 subunit upregulation contributes to peripheral nerve injury-induced tactile allodynia
Q22253850Spinocerebellar ataxia type 6 mutation alters P-type calcium channel function
Q48213714Splicing of alpha 1A subunit gene generates phenotypic variants of P- and Q-type calcium channels
Q41524977Stable and functional expression of the calcium channel alpha 1 subunit from smooth muscle in somatic cell lines
Q41518396Stable co-expression of calcium channel alpha 1, beta and alpha 2/delta subunits in a somatic cell line
Q48326483Structural determinants of ion selectivity in brain calcium channel
Q46111206Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin
Q24537292Structural elements in domain IV that influence biophysical and pharmacological properties of human alpha1A-containing high-voltage-activated calcium channels
Q33544674Structure and function of neuronal Ca2+ channels and their role in neurotransmitter release
Q46459475Structures and functions of calcium channel beta subunits
Q34808665Subtype-selective reconstitution of synaptic transmission in sympathetic ganglion neurons by expression of exogenous calcium channels
Q41745969Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function.
Q49049598Subunit regulation of the neuronal alpha 1A Ca2+ channel expressed in Xenopus oocytes
Q48537185Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.
Q24614506Synaptic targeting of N-type calcium channels in hippocampal neurons
Q24321661Systematic identification of splice variants in human P/Q-type channel alpha1(2.1) subunits: implications for current density and Ca2+-dependent inactivation
Q73581877T-type Ca2+ current properties are not modified by Ca2+ channel beta subunit depletion in nodosus ganglion neurons
Q34115407T-type and N-type calcium channels of Xenopus oocytes: evidence for specific interactions with beta subunits
Q32123389Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes
Q36329427Targeted disruption of the Ca2+ channel beta3 subunit reduces N- and L-type Ca2+ channel activity and alters the voltage-dependent activation of P/Q-type Ca2+ channels in neurons.
Q35682314Targeting mechanisms of high voltage-activated Ca2+ channels
Q37605352Targeting voltage-gated calcium channels for neuropathic pain management
Q39450985The Ca2+ channel beta3 subunit differentially modulates G-protein sensitivity of alpha1A and alpha1B Ca2+ channels.
Q48849805The Cav2.1/alpha1A (P/Q-type) voltage-dependent calcium channel mediates inhibitory neurotransmission onto mouse cerebellar Purkinje cells
Q33892693The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.
Q26781422The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential
Q50760510The alpha 1E calcium channel exhibits permeation properties similar to low-voltage-activated calcium channels.
Q49021762The alpha 2/delta subunit of voltage sensitive Ca2+ channels is a single transmembrane extracellular protein which is involved in regulated secretion
Q44084421The alpha(1A) subunits of rat brain calcium channels are developmentally regulated by alternative RNA splicing
Q34081801The alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate receptor trafficking regulator "stargazin" is related to the claudin family of proteins by Its ability to mediate cell-cell adhesion
Q37502776The ataxic Cacna1a-mutant mouse rolling nagoya: an overview of neuromorphological and electrophysiological findings
Q49028021The beta 1-subunit is essential for modulation by protein kinase C of an human and a non-human L-type Ca2+ channel
Q34090186The beta subunit controls the gating and dihydropyridine sensitivity of the skeletal muscle Ca2+ channel
Q40240262The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function.
Q33739563The carboxy-terminal fragment of alpha(1A) calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells.
Q24628942The cerebellum and migraine
Q33721644The concept of a calcium sensor in transmitter release
Q43833683The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function
Q28245880The expression of voltage-dependent calcium channel beta subunits in human cerebellum
Q34498011The function of Ca(2+) channel subtypes in exocytotic secretion: new perspectives from synaptic and non-synaptic release.
Q39888161The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition
Q43854340The interaction between the I-II loop and the III-IV loop of Cav2.1 contributes to voltage-dependent inactivation in a beta -dependent manner.
Q33914048The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of alpha2delta subunits is key to trafficking voltage-gated Ca2+ channels
Q35932365The molecular genetics of migraine
Q71902710The molecular identity of Ca channel alpha 1-subunits expressed in rat sympathetic neurons
Q46162082The molecular mode of action of the Ca agonist (?) BAY K 8644 on the cardiac Ca channel
Q36053129The nematode neuropeptide, AF2 (KHEYLRF-NH2), increases voltage-activated calcium currents in Ascaris suum muscle.
Q30175691The polyglutamine expansion in spinocerebellar ataxia type 6 causes a beta subunit-specific enhanced activation of P/Q-type calcium channels in Xenopus oocytes.
Q37159644The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2.
Q30495678The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia
Q42057968The triad targeting signal of the skeletal muscle calcium channel is localized in the COOH terminus of the alpha(1S) subunit
Q30155988The β Subunit of Voltage-Gated Ca2+Channels
Q28139662Three new familial hemiplegic migraine mutants affect P/Q-type Ca(2+) channel kinetics
Q36836787Tissue-specific expression of splice variants of the mouse voltage-gated calcium channel alpha2/delta subunit
Q41527106Toward understanding the molecular pathology of Huntington's disease.
Q44087369Toxicity and endocytosis of spinocerebellar ataxia type 6 polyglutamine domains: role of myosin IIb.
Q48952756Toxin-resistant calcium currents in embryonic mouse sensory neurons
Q41582134Toxins affecting calcium channels in neurons
Q36680865Transcriptional regulation of the neuronal L-type calcium channel alpha 1D subunit gene.
Q98735778Transcriptomic Changes Resulting From STK32B Overexpression Identify Pathways Potentially Relevant to Essential Tremor
Q70901399Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels
Q49010921Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.
Q48975234Transfer of high sensitivity for benzothiazepines from L-type to class A (BI) calcium channels
Q37886522Transsynaptic channelosomes: non-conducting roles of ion channels in synapse formation
Q37209209Tuning voltage-gated channel activity and cellular excitability with a sphingomyelinase
Q48971899Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity
Q37079538Two novel alleles of tottering with distinct Ca(v)2.1 calcium channel neuropathologies
Q43540445Upregulation of dorsal root ganglion (alpha)2(delta) calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats.
Q42538760Use of a purified and functional recombinant calcium-channel beta4 subunit in surface-plasmon resonance studies
Q48820477Voltage dependent calcium channels in cerebellar granule cell primary cultures
Q35860087Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons
Q38344235Voltage-dependent binding and calcium channel current inhibition by an anti-alpha 1D subunit antibody in rat dorsal root ganglion neurones and guinea-pig myocytes
Q49064887Voltage-dependent inactivation in a cardiac-skeletal chimeric calcium channel
Q28242997Voltage-gated calcium channels
Q37298134Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology
Q59530617Voltage-gated calcium channels, calcium signaling, and channelopathies
Q57484915Voltage-gated calcium channels: their discovery, function and importance as drug targets
Q34186741Voltage-gated rearrangements associated with differential beta-subunit modulation of the L-type Ca(2+) channel inactivation
Q35224872Voltage-sensitive Ca2+ channels
Q36710567Voltage-sensitive Na+ channels: motifs, modes and modulation
Q28509521Whole-cell and single-channel analysis of P-type calcium currents in cerebellar Purkinje cells of leaner mutant mice
Q89963752Zebrafish as a Model System for the Study of Severe CaV2.1 (α1A) Channelopathies
Q41434876Zebrafish calls for reinterpretation for the roles of P/Q calcium channels in neuromuscular transmission
Q36863018alpha1-beta interaction in voltage-gated cardiac L-type calcium channels
Q33743657beta subunits influence the biophysical and pharmacological differences between P- and Q-type calcium currents expressed in a mammalian cell line
Q47070897dSLo interacting protein 1, a novel protein that interacts with large-conductance calcium-activated potassium channels.
Q72420987omega-Grammotoxin blocks action-potential-induced Ca2+ influx and whole-cell Ca2+ current in rat dorsal-root ganglion neurons