DNA bending by thyroid hormone receptor: influence of half-site spacing and RXR.

scientific article

DNA bending by thyroid hormone receptor: influence of half-site spacing and RXR. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/23.5.811
P932PMC publication ID306764
P698PubMed publication ID7708497
P5875ResearchGate publication ID15489682

P2093author name stringM A Lazar
D Katz
D D Dimaculangan
K Shulemovich
P2860cites workRXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elementsQ24318447
Opposite orientations of DNA bending by c-Myc and MaxQ24564314
The steroid and thyroid hormone receptor superfamilyQ27861095
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficientlyQ28208673
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signallingQ28208726
Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver proteinQ28212739
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptorsQ28297907
H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response elementQ28508930
Dominant negative activity of an endogenous thyroid hormone receptor variant (alpha 2) is due to competition for binding sites on target genesQ28577094
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptorsQ29615768
Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vectorQ69314090
Human estrogen receptor bound to an estrogen response element bends DNAQ70683821
Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptorQ72689852
The effects of P-box substitutions in thyroid hormone receptor on DNA binding specificityQ72866653
Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3',5-triiodo-L-thyronineQ72908016
Protein-induced bending as a transcriptional switchQ72968208
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptorsQ31159950
Synthetic curved DNA sequences can act as transcriptional activators in Escherichia coliQ33591850
Molecular characterization of the GCN4-DNA complexQ33733434
Detection of localized DNA flexibilityQ34338118
Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormoneQ36556508
Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptorQ36735798
Myc/Max and other helix-loop-helix/leucine zipper proteins bend DNA toward the minor grooveQ37338898
Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elementsQ37630259
Steroid receptor family: structure and functionsQ37938849
The C/EBP family of proteins distorts DNA upon binding but does not introduce a large directed bend.Q38304292
DNA targets for certain bZIP proteins distinguished by an intrinsic bendQ38308088
Thyroid hormone receptor-induced bending of specific DNA sequences is modified by an accessory factor.Q38322484
Thyroid hormone alters the DNA binding properties of chicken thyroid hormone receptors alpha and betaQ38325856
Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elementsQ38329547
Fos-Jun heterodimers and Jun homodimers bend DNA in opposite orientations: implications for transcription factor cooperativityQ38334205
Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimerQ38343050
Nuclear receptors enhance our understanding of transcription regulationQ39324380
Empirical estimation of protein-induced DNA bending angles: applications to lambda site-specific recombination complexesQ40556347
DNA bending by retinoid X receptor-containing retinoid and thyroid hormone receptor complexesQ40656402
Thyroid hormone receptors: multiple forms, multiple possibilitiesQ40822820
Catabolite activator protein-induced DNA bending in transcription initiationQ41129333
Oligomeric binding of T3 receptor is required for maximal T3 response.Q41166252
Endogenous retinoid X receptors can function as hormone receptors in pituitary cellsQ41431671
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand bindingQ41436527
Thyroid hormone receptor monomer, homodimer, and heterodimer (with retinoid-X receptor) contact different nucleotide sequences in thyroid hormone response elementsQ41438501
Divergent dimerization properties of mutant beta 1 thyroid hormone receptors are associated with different dominant negative activitiesQ41458129
Nucleotide substitutions differentially affect direct repeat and palindromic thyroid hormone response elementsQ41476093
Transcriptional regulation by triiodothyronine requires synergistic action of the thyroid receptor with another trans-acting factorQ41606962
Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimersQ41639104
H-2RIIBP expressed from a baculovirus vector binds to multiple hormone response elementsQ41641361
Selective DNA bending by a variety of bZIP proteinsQ42057338
Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repressionQ42069854
The conserved ninth C-terminal heptad in thyroid hormone and retinoic acid receptors mediates diverse responses by affecting heterodimer but not homodimer formationQ42508346
Positive and negative effects of DNA bending on activation of transcription from a distant siteQ42605034
Rotational orientation of upstream curved DNA affects promoter function in Bacillus subtilisQ42641626
High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociationQ45214892
Retinoic acid and thyroid hormone induce gene expression through a common responsive element.Q46001994
Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.Q46039694
Determinants for selective RAR and TR recognition of direct repeat HREs.Q46177795
Thyroid hormone alters in vitro DNA binding of monomers and dimers of thyroid hormone receptorsQ46289969
DNA Binding and Dimerization Determinants for Thyroid Hormone Receptor α and Its Interaction with a Nuclear ProteinQ46547471
CAT vectors for analysis of eukaryotic promoters and enhancers.Q54438149
Conformational changes in chicken thyroid hormone receptor alpha 1 induced by binding to ligand or to DNA.Q54663454
DNA bending by Fos and Jun: the flexible hinge modelQ57963231
Cooperativity of the glucocorticoid receptor and the CACCC-box binding factorQ59098605
Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimersQ67488391
The unique C-termini of the thyroid hormone receptor variant, c-erbA alpha 2, and thyroid hormone receptor alpha 1 mediate different DNA-binding and heterodimerization propertiesQ67489756
Thyroid hormone responsiveness in human growth hormone-related genes. Possible correlation with receptor-induced DNA conformational changesQ67728273
Ligand-dependent synergy of thyroid hormone and retinoid X receptorsQ67864756
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)811-818
P577publication date1995-03-01
P1433published inNucleic Acids ResearchQ135122
P1476titleDNA bending by thyroid hormone receptor: influence of half-site spacing and RXR.
P478volume23

Reverse relations

cites work (P2860)
Q71902705A Purkinje cell protein-2 intronic thyroid hormone response element binds developmentally regulated thyroid hormone receptor-nuclear protein complexes
Q42466639AP-1 and T3RE cis elements operate as a functional unit in the transcriptional control of the human malic enzyme gene
Q24544646Binding of type II nuclear receptors and estrogen receptor to full and half-site estrogen response elements in vitro
Q47628209Conformational changes in the DNA-binding domains of the ecdysteroid receptor during the formation of a complex with the hsp27 response element.
Q35212571Context-dependent transcription: all politics is local
Q58707878Cross-talk between thyroid hormone and specific retinoid X receptor subtypes in yeast selectively regulates cognate ligand actions
Q39716907DNA bending by the silencer protein NeP1 is modulated by TR and RXR
Q73414011DNA bending is induced by binding of the glucocorticoid receptor DNA binding domain and progesterone receptors to their response element
Q43843420Differential modulation of DNA conformation by estrogen receptors alpha and beta
Q37273599Ets-1 p51 and p42 isoforms differentially modulate Stromelysin-1 promoter according to induced DNA bend orientation
Q42113563Functional divergence between the half-sites of the DNA-binding sequence for the yeast transcriptional regulator Rap1p
Q42606609Identification and characterization of a nuclear receptor subfamily I member in the Platyhelminth Schistosoma mansoni (SmNR1).
Q33733927LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling
Q38759329Liganded Thyroid Hormone Receptors Transactivate the DNA Methyltransferase 3a Gene in Mouse Neuronal Cells
Q33559752Modular insulators: genome wide search for composite CTCF/thyroid hormone receptor binding sites
Q34283432Nuclear hormone receptors in parasitic helminths
Q40022324Prebending the estrogen response element destabilizes binding of the estrogen receptor DNA binding domain
Q40023845Proposed mechanism for the stabilization of nuclear receptor DNA binding via protein dimerization
Q35089956The thyroid hormone receptor and the insulator protein CTCF: two different factors with overlapping functions
Q33295447Thyroid hormone receptor orthologues from invertebrate species with emphasis on Schistosoma mansoni

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