scholarly article | Q13442814 |
P2093 | author name string | Chambon P | |
Gronemeyer H | |||
Zechel C | |||
Shen XQ | |||
P2860 | cites work | RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements | Q24318447 |
RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors | Q24555693 | ||
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling | Q24563064 | ||
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Q27651364 | ||
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements | Q27731441 | ||
The steroid and thyroid hormone receptor superfamily | Q27861095 | ||
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently | Q28208673 | ||
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling | Q28208726 | ||
Homo- and heteronuclear NMR studies of the human retinoic acid receptor beta DNA-binding domain: sequential assignments and identification of secondary structure elements | Q28211214 | ||
Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein | Q28212739 | ||
Solution structure of the DNA-binding domain of the oestrogen receptor | Q28263533 | ||
Protein-protein contacts in the glucocorticoid receptor homodimer influence its DNA binding properties | Q57607831 | ||
Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element | Q59070120 | ||
Two nuclear signalling pathways for vitamin D | Q59098586 | ||
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer | Q67927526 | ||
Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation | Q67927534 | ||
DNA Binding Properties of the Vitamin D3Receptor Zinc Finger Region | Q68274304 | ||
Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor | Q69208244 | ||
An everted repeat mediates retinoic acid induction of the gamma F-crystallin gene: evidence of a direct role for retinoids in lens development | Q70567677 | ||
Protein-protein interactions between the DNA-binding domains of nuclear receptors: influence on DNA-binding | Q70730977 | ||
The c-erb-A protein is a high-affinity receptor for thyroid hormone | Q28282719 | ||
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors | Q28297907 | ||
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors | Q28326688 | ||
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors | Q29615768 | ||
Gene regulation by steroid hormones | Q29618291 | ||
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors | Q31159950 | ||
Evolution of the nuclear receptor gene superfamily | Q33937509 | ||
H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes | Q33937627 | ||
RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo | Q34052386 | ||
The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains. | Q34064607 | ||
Multiplicity generates diversity in the retinoic acid signalling pathways | Q35236424 | ||
Retinoid receptors in vertebrate limb development | Q35260064 | ||
Efficient transactivation by retinoic acid receptors in yeast requires retinoid X receptors | Q36290030 | ||
Retinoids and their receptors in differentiation, embryogenesis, and neoplasia | Q36448344 | ||
Transcription activation by estrogen and progesterone receptors | Q36468309 | ||
Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXR beta) enhances DNA binding and TH-dependent transcriptional activation | Q37066332 | ||
The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats. | Q37630287 | ||
The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers. | Q38312085 | ||
Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding | Q38319122 | ||
PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene. | Q38320134 | ||
Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors | Q38322521 | ||
Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors | Q38329494 | ||
A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter | Q38334173 | ||
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor | Q38341530 | ||
Nuclear receptors enhance our understanding of transcription regulation | Q39324380 | ||
Defining a minimal estrogen receptor DNA binding domain | Q40405712 | ||
Site-specific mutagenesis using asymmetric polymerase chain reaction and a single mutant primer | Q40527637 | ||
The molecular and genetic dissection of the retinoid signalling pathway | Q40798560 | ||
Mechanisms of transactivation by retinoic acid receptors | Q40856444 | ||
The N-terminal DNA-binding 'zinc finger' of the oestrogen and glucocorticoid receptors determines target gene specificity | Q41092852 | ||
Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid | Q41608901 | ||
Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation | Q41612337 | ||
The conserved ninth C-terminal heptad in thyroid hormone and retinoic acid receptors mediates diverse responses by affecting heterodimer but not homodimer formation | Q42508346 | ||
Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids | Q43460186 | ||
Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin | Q43632385 | ||
Solution structure of the glucocorticoid receptor DNA-binding domain | Q45817037 | ||
Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. | Q46039694 | ||
Determinants of target gene specificity for steroid/thyroid hormone receptors | Q46051437 | ||
Determinants for selective RAR and TR recognition of direct repeat HREs. | Q46177795 | ||
DNA recognition by the oestrogen receptor: from solution to the crystal | Q47964761 | ||
All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. | Q48153966 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1414-1424 | |
P577 | publication date | 1994-03-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements | |
P478 | volume | 13 |
Q24308781 | A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity |
Q34343049 | A mollusk retinoic acid receptor (RAR) ortholog sheds light on the evolution of ligand binding. |
Q33887513 | A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers |
Q39447809 | A novel role for helix 12 of retinoid X receptor in regulating repression |
Q41015780 | A role for helix 3 of the TRbeta ligand-binding domain in coactivator recruitment identified by characterization of a third cluster of mutations in resistance to thyroid hormone |
Q24544646 | Binding of type II nuclear receptors and estrogen receptor to full and half-site estrogen response elements in vitro |
Q24554585 | Characterization of the DNA-binding and dimerization properties of the nuclear orphan receptor germ cell nuclear factor |
Q33584820 | Cloning retinoid and peroxisome proliferator-activated nuclear receptors of the Pacific oyster and in silico binding to environmental chemicals |
Q64913381 | Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity. |
Q40393284 | DNA bending by thyroid hormone receptor: influence of half-site spacing and RXR. |
Q34631474 | Deregulated transcription factors in leukemia |
Q36550845 | Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor |
Q24563324 | Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1 |
Q36560247 | Direct repeats bind the EcR/USP receptor and mediate ecdysteroid responses in Drosophila melanogaster |
Q37201722 | Dynamic and combinatorial control of gene expression by nuclear retinoic acid receptors (RARs). |
Q40016745 | Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer |
Q37689018 | From carrot to clinic: an overview of the retinoic acid signaling pathway |
Q36797684 | General molecular biology and architecture of nuclear receptors |
Q36549937 | Genetic dissection of thyroid hormone receptor beta: identification of mutations that separate hormone binding and transcriptional activation |
Q33693856 | Hif1α down-regulation is associated with transposition of great arteries in mice treated with a retinoic acid antagonist |
Q41045818 | Human nuclear receptor heterodimers: opportunities for detecting targets of transcriptional regulation using yeast. |
Q36061886 | Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors |
Q39634704 | Mechanism of high-mobility group protein B enhancement of progesterone receptor sequence-specific DNA binding. |
Q27852289 | Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O 3) in acute promyelocytic leukemia |
Q77355947 | Microsecond time scale dynamics in the RXR DNA-binding domain from a combination of spin-echo and off-resonance rotating frame relaxation measurements |
Q28367742 | New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid |
Q38922128 | Nuclear retinoid receptors and pregnancy: placental transfer, functions, and pharmacological aspects |
Q39643895 | Promoter context determines the role of proteasome in ligand-dependent occupancy of retinoic acid responsive elements |
Q36876232 | Quantification of Cooperativity in Heterodimer-DNA Binding Improves the Accuracy of Binding Specificity Models. |
Q37695128 | RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. |
Q33882753 | Regulation of cytochrome P450 (CYP) genes by nuclear receptors. |
Q30408649 | Retinoic acid actions through mammalian nuclear receptors |
Q33915545 | Retinoid X receptor alpha forms tetramers in solution |
Q38961328 | Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings |
Q36139646 | Separation of retinoid X receptor homo- and heterodimerization functions |
Q27638917 | Structural basis of VDR-DNA interactions on direct repeat response elements |
Q37414946 | Structural basis of androgen receptor binding to selective androgen response elements. |
Q28115652 | Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA |
Q24644790 | Structure of the heterodimeric ecdysone receptor DNA-binding complex |
Q24652983 | Structure of the progesterone receptor-deoxyribonucleic acid complex: novel interactions required for binding to half-site response elements |
Q28509358 | The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18 |
Q34619185 | The divergent orphan nuclear receptor ODR-7 regulates olfactory neuron gene expression via multiple mechanisms in Caenorhabditis elegans |
Q36554302 | The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat |
Q24815982 | The proliferating cell nuclear antigen regulates retinoic acid receptor transcriptional activity through direct protein-protein interaction. |
Q33886680 | The promoter context is a decisive factor in establishing selective responsiveness to nuclear class II receptors |
Q82863470 | The vitamin D(3) receptor in the context of the nuclear receptor superfamily : The central role of the retinoid X receptor |
Q34294723 | Transcription factors as drug targets: opportunities for therapeutic selectivity. |
Q37411882 | Understanding nuclear receptor form and function using structural biology |
Q36920549 | Vitamin A and retinoid signaling: genomic and nongenomic effects |
Q40393070 | Vitamin D receptor contains multiple dimerization interfaces that are functionally different |
Q36555582 | Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. |
Q36931713 | Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective |
Q24561965 | Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development |
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