scholarly article | Q13442814 |
P2093 | author name string | Chambon P | |
Gronemeyer H | |||
Chen Z | |||
White J | |||
Chen JY | |||
Mader S | |||
P2860 | cites work | A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR | Q24306431 |
RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements | Q24318447 | ||
RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors | Q24555693 | ||
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling | Q24563064 | ||
Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids | Q24563907 | ||
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA | Q27651364 | ||
9-cis retinoic acid is a high affinity ligand for the retinoid X receptor | Q28119031 | ||
Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently | Q28208673 | ||
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling | Q28208726 | ||
Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein | Q28212739 | ||
Solution structure of the DNA-binding domain of the oestrogen receptor | Q28263533 | ||
All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs. | Q48153966 | ||
Developmental biology. Reading the retinoid signals. | Q52241034 | ||
Protein-protein contacts in the glucocorticoid receptor homodimer influence its DNA binding properties | Q57607831 | ||
Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element | Q59070120 | ||
Two nuclear signalling pathways for vitamin D | Q59098586 | ||
Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers | Q67488391 | ||
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer | Q67927526 | ||
Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation | Q67927534 | ||
Thyroid hormone receptor dimerization function maps to a conserved subregion of the ligand binding domain | Q67984001 | ||
Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor | Q69208244 | ||
Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction between monomers | Q28276809 | ||
The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors | Q28297907 | ||
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors | Q28326688 | ||
9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα | Q28343032 | ||
Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors | Q29615768 | ||
Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors | Q31159950 | ||
H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes | Q33937627 | ||
Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors | Q34234016 | ||
A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene | Q34321529 | ||
Multiplicity generates diversity in the retinoic acid signalling pathways | Q35236424 | ||
Retinoid receptors in vertebrate limb development | Q35260064 | ||
Retinoids and their receptors in differentiation, embryogenesis, and neoplasia | Q36448344 | ||
Transcription activation by estrogen and progesterone receptors | Q36468309 | ||
Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development | Q36506314 | ||
Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor | Q36735798 | ||
Multiple parameters control the selectivity of nuclear receptors for their response elements. Selectivity and promiscuity in response element recognition by retinoic acid receptors and retinoid X receptors | Q38322521 | ||
Binding characteristics of the thyroid hormone receptor homo- and heterodimers to consensus AGGTCA repeat motifs | Q38327954 | ||
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene | Q38330731 | ||
A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter | Q38334173 | ||
Multiple cell type-specific proteins differentially regulate target sequence recognition by the alpha retinoic acid receptor | Q38338308 | ||
Protein-protein interactions facilitate DNA binding by the glucocorticoid receptor DNA-binding domain | Q38339682 | ||
Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor | Q38341530 | ||
Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer | Q38343050 | ||
Nuclear receptors enhance our understanding of transcription regulation | Q39324380 | ||
Defining a minimal estrogen receptor DNA binding domain | Q40405712 | ||
The contribution of the N- and C-terminal regions of steroid receptors to activation of transcription is both receptor and cell-specific. | Q40448463 | ||
A 22-amino-acid peptide restores DNA-binding activity to dimerization-defective mutants of the estrogen receptor | Q40640074 | ||
Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR. | Q40872478 | ||
Functional characterization of a natural retinoic acid responsive element | Q41083429 | ||
Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors | Q41601861 | ||
Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors | Q41602857 | ||
Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid | Q41608901 | ||
Immunodetection of multiple species of retinoic acid receptor alpha: evidence for phosphorylation | Q41612337 | ||
Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers | Q41639104 | ||
Heterodimeric receptor complexes determine 3,5,3'-triiodothyronine and retinoid signaling specificities | Q43753385 | ||
An estrogen-responsive element derived from the 5' flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells | Q44741237 | ||
High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation | Q45214892 | ||
Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity | Q45217737 | ||
Solution structure of the glucocorticoid receptor DNA-binding domain | Q45817037 | ||
Retinoic acid and thyroid hormone induce gene expression through a common responsive element. | Q46001994 | ||
Determinants of target gene specificity for steroid/thyroid hormone receptors | Q46051437 | ||
Thyroid hormone alters in vitro DNA binding of monomers and dimers of thyroid hormone receptors | Q46289969 | ||
P433 | issue | 13 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5029-5041 | |
P577 | publication date | 1993-12-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains | |
P478 | volume | 12 |
Q40468056 | 9-cis retinoic acid signaling: changing partners causes some excitement |
Q40793054 | A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1. |
Q38301770 | A functional glucocorticoid-responsive unit composed of two overlapping inactive receptor-binding sites: evidence for formation of a receptor tetramer |
Q24609094 | A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily |
Q39715522 | A novel type of retinoic acid response element in the second intron of the mouse H2Kb gene is activated by the RAR/RXR heterodimer. |
Q36553456 | A retinoic acid response element that overlaps an estrogen response element mediates multihormonal sensitivity in transcriptional activation of the lactoferrin gene |
Q37638476 | Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity |
Q24311404 | Adenovirus E1A functions as a cofactor for retinoic acid receptor beta (RAR beta) through direct interaction with RAR beta |
Q37233353 | All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor |
Q33957795 | Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA. |
Q24310501 | An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita |
Q38354733 | Characterization of a dominant negative mutant form of the HNF-4 orphan receptor |
Q40322576 | Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM. |
Q42152410 | Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings |
Q64913381 | Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity. |
Q52671633 | Conservation of DNA and ligand binding properties of retinoid X receptor from the placozoan Trichoplax adhaerens to human. |
Q35725003 | DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified |
Q38305506 | Difference and similarity of DNA sequence recognized by VDR homodimer and VDR/RXR heterodimer |
Q24563324 | Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1 |
Q37630259 | Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements |
Q40726582 | Dimerization of v-erbA on inverted repeats |
Q48088353 | Direct regulation of vHnf1 by retinoic acid signaling and MAF-related factors in the neural tube |
Q36560247 | Direct repeats bind the EcR/USP receptor and mediate ecdysteroid responses in Drosophila melanogaster |
Q33871117 | Dual FRET assay for detecting receptor protein interaction with DNA. |
Q41431671 | Endogenous retinoid X receptors can function as hormone receptors in pituitary cells |
Q40016745 | Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer |
Q77639038 | Expression of retinoic acid receptor and retinoid X receptor subtypes in rat liver cells: implications for retinoid signalling in parenchymal, endothelial, Kupffer and stellate cells |
Q37689018 | From carrot to clinic: an overview of the retinoic acid signaling pathway |
Q36637419 | Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells |
Q33693856 | Hif1α down-regulation is associated with transposition of great arteries in mice treated with a retinoic acid antagonist |
Q38356179 | Intron retention generates a novel isoform of the murine vitamin D receptor that acts in a dominant negative way on the vitamin D signaling pathway |
Q36775185 | Locust retinoid X receptors: 9-Cis-retinoic acid in embryos from a primitive insect |
Q33587871 | Metabolism to a response pathway selective retinoid ligand during axial pattern formation |
Q41526912 | Modified steroid receptors and steroid-inducible promoters as genetic switches for gene therapy |
Q36549658 | Natural vitamin D3 response elements formed by inverted palindromes: polarity-directed ligand sensitivity of vitamin D3 receptor-retinoid X receptor heterodimer-mediated transactivation. |
Q28367742 | New retinoid X receptor subtypes in zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid |
Q61818611 | Nuclear receptor superfamily: Principles of signaling |
Q34282476 | Nuclear-receptor interactions on DNA-response elements |
Q40732567 | PAV-1, a new rat hepatic stellate cell line converts retinol into retinoic acid, a process altered by ethanol. |
Q28203481 | Promoter of FGF8 reveals a unique regulation by unliganded RARalpha |
Q37695128 | RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. |
Q41844763 | Rational design of an estrogen receptor mutant with altered DNA-binding specificity |
Q37248134 | Regulation of CD8(+) T cell functions by RARgamma. |
Q33803303 | Regulation of type 1 iodothyronine deiodinase by LXRα |
Q39652773 | Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells |
Q30306797 | Retinoid X receptor and its partners in the nuclear receptor family |
Q35840016 | Retinoid activation of retinoic acid receptors but not of retinoid X receptors promotes cellular differentiation and replication of human cytomegalovirus in embryonal cells |
Q40372674 | Retinoids and mouse embryonic development |
Q37311048 | Retinoids regulate human amniotic tissue-type plasminogen activator gene by a two-step mechanism |
Q36139646 | Separation of retinoid X receptor homo- and heterodimerization functions |
Q44312225 | Sequences required for the transition from monomeric to homodimeric forms of thyroid hormone receptor alpha and v-erbA. |
Q41815633 | Small-molecule hormones: molecular mechanisms of action |
Q28369692 | Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists |
Q27638917 | Structural basis of VDR-DNA interactions on direct repeat response elements |
Q37414946 | Structural basis of androgen receptor binding to selective androgen response elements. |
Q27730227 | Structural determinants of nuclear receptor assembly on DNA direct repeats |
Q27760617 | Structural elements of an orphan nuclear receptor-DNA complex |
Q27663271 | Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element |
Q27621610 | Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1 |
Q24644790 | Structure of the heterodimeric ecdysone receptor DNA-binding complex |
Q35907842 | The C6 zinc cluster dictates asymmetric binding by HAP1. |
Q36554543 | The Essential DNA-Binding Protein sap1 of Schizosaccharomyces pombe Contains Two Independent Oligomerization Interfaces That Dictate the Relative Orientation of the DNA-Binding Domain |
Q37630287 | The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats. |
Q41941029 | The eccentric cleavage product of β-carotene, β-apo-13-carotenone, functions as an antagonist of RXRα. |
Q34763533 | The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids |
Q33886680 | The promoter context is a decisive factor in establishing selective responsiveness to nuclear class II receptors |
Q36561262 | The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal |
Q44319351 | The role of a retinoic acid response element in establishing the anterior neural expression border of Hoxd4 transgenes. |
Q34974992 | The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling |
Q82863470 | The vitamin D(3) receptor in the context of the nuclear receptor superfamily : The central role of the retinoid X receptor |
Q35814179 | Transcriptional Factors Mediating Retinoic Acid Signals in the Control of Energy Metabolism |
Q36053034 | Transcriptional activities of retinoic acid receptors |
Q37411882 | Understanding nuclear receptor form and function using structural biology |
Q80416865 | V-erba homodimers mediate the potent dominant negative activity of v-erba on everted repeats |
Q34926608 | Variations on a theme: the alternate translocations in APL. |
Q40018060 | Vitamin D interferes with transactivation of the growth hormone gene by thyroid hormone and retinoic acid |
Q40393070 | Vitamin D receptor contains multiple dimerization interfaces that are functionally different |
Q52552156 | Vitamin D receptor interactions with the murine osteopontin response element. |
Q35802827 | Vitamin D receptor-DNA interactions |
Q41449208 | Vitamin D3-thyroid hormone receptor heterodimer polarity directs ligand sensitivity of transactivation |
Q36555582 | Widely spaced, directly repeated PuGGTCA elements act as promiscuous enhancers for different classes of nuclear receptors. |
Q33269869 | Widespread Alu repeat-driven expansion of consensus DR2 retinoic acid response elements during primate evolution |
Q36931713 | Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective |
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