Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras

scientific article published on September 2005

Immortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1044687353
P356DOI10.1038/SJ.ONC.1208809
P698PubMed publication ID16027734
P5875ResearchGate publication ID7716660

P2093author name stringAlexander Hoffmann
Thomas D Gilmore
Oliver Schmah
Maria-Emily R Gapuzan
Ashley D Pollock
P2860cites workRecruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repressionQ24559651
To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosisQ28190313
The c-Rel transcription factor and B-cell proliferation: a deal with the devilQ28241767
An essential role for NF-kappaB in preventing TNF-alpha-induced cell deathQ29614707
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylationQ29614709
Suppression of TNF-alpha-induced apoptosis by NF-kappaBQ29618717
Genes involved in senescence and immortalizationQ34076841
Development of 3T3-like lines from Balb-c mouse embryo cultures: transformation susceptibility to SV40.Q34206077
Ras effectors and their role in mitogenesis and oncogenesisQ34439160
p53-Mdm2--the affair that never endsQ34605732
Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethalityQ35064315
Isolation of ras GTP-binding mutants using an in situ colony-binding assayQ35613440
beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancerQ38361640
p19ARF directly and differentially controls the functions of c-Myc independently of p53.Q40516548
Transfection of a dominant-negative mutant NF-kB inhibitor (IkBm) represses p53-dependent apoptosis in acute lymphoblastic leukemia cells: interaction of IkBm and p53Q40619108
p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapyQ40717571
Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-kappaB have a malignantly transformed phenotypeQ40736254
Function and regulation of ras.Q40835314
Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalphaQ40881293
NF-kappa B is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesisQ40896004
Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.Q41074033
Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformationQ42795799
Oncoprotein suppression of tumor necrosis factor-induced NF kappa B activation is independent of Raf-controlled pathwaysQ43990096
NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.Q45982548
Human Arf tumor suppressor specifically interacts with chromatin containing the promoter of rRNA genes.Q51595537
Increasing complexity of Ras signaling.Q53429989
Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitmentQ74244267
An NF-kappaB-specific inhibitor, IkappaBalpha, binds to and inhibits cyclin-dependent kinase 4Q79300288
Loss of c-abl facilitates anchorage-independent growth of p53- and RB- deficient primary mouse embryonic fibroblastsQ80586970
P433issue43
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
knockout mouseQ1364740
phenotypic heterogeneityQ18388100
P304page(s)6574-6583
P577publication date2005-09-01
P1433published inOncogeneQ1568657
P1476titleImmortalized fibroblasts from NF-kappaB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor alpha after transformation by v-Ras
P478volume24

Reverse relations

cites work (P2860)
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