Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs

scientific article

Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCP.20423
P698PubMed publication ID15920762

P2093author name stringBukhtiar H Shah
Kevin J Catt
Farzana B Shah
Adrienne Neithardt
David B Chu
P2860cites workPDK1, the master regulator of AGC kinase signal transductionQ24297416
Cell signaling by receptor tyrosine kinasesQ27860474
The phosphoinositide 3-kinase pathwayQ27860738
Gonadotropin-releasing hormone receptorsQ28256257
PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survivalQ28569674
Src homology 3 binding sites in the P2Y2 nucleotide receptor interact with Src and regulate activities of Src, proline-rich tyrosine kinase 2, and growth factor receptorsQ30164357
Epidermal growth factor receptor: mechanisms of activation and signalling.Q34185055
Akt/protein kinase B promotes organ growth in transgenic miceQ34276940
Neuregulin and ErbB receptor signaling pathways in the nervous systemQ34278032
Genetic models meet trophic mechanisms: EGF family members are gliatrophins in DrosophilaQ34552557
Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway.Q34691469
Functions of PI 3-kinase in development of the nervous systemQ34783898
Class I phosphoinositide 3-kinases.Q35097646
Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinasesQ35126873
A central role of EGF receptor transactivation in angiotensin II -induced cardiac hypertrophyQ35136326
Metalloprotease-dependent ErbB ligand shedding in mediating EGFR transactivation and vascular remodellingQ35594158
The dark side of Ras: regulation of apoptosisQ35603375
GPCR-mediated transactivation of RTKs in the CNS: mechanisms and consequencesQ35617743
Advances in protein kinase B signalling: AKTion on multiple frontsQ35766370
Phosphoinositide 3-kinases as targets for therapeutic interventionQ35794071
Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt.Q35995684
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptorQ36324611
EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathwayQ40517007
Differential pathways of angiotensin II-induced extracellularly regulated kinase 1/2 phosphorylation in specific cell types: role of heparin-binding epidermal growth factorQ40555984
Neuropeptide-induced transactivation of a neuronal epidermal growth factor receptor is mediated by metalloprotease-dependent formation of heparin-binding epidermal growth factorQ40624040
Dependence of gonadotropin-releasing hormone-induced neuronal MAPK signaling on epidermal growth factor receptor transactivationQ40687990
ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinaseQ40744542
An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.Q40919265
Epidermal growth factor protects epithelial cells against Fas-induced apoptosis. Requirement for Akt activationQ40949162
Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathwayQ41197935
PYK2 links G(q)alpha and G(13)alpha signaling to NF-kappa B activation.Q43660533
Calcium-independent activation of extracellularly regulated kinases 1 and 2 by angiotensin II in hepatic C9 cells: roles of protein kinase Cdelta, Src/proline-rich tyrosine kinase 2, and epidermal growth receptor trans-activationQ43865604
Transactivation joins multiple tracks to the ERK/MAPK cascadeQ44552387
Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptorQ44582560
LY294002, an inhibitor of phosphoinositide 3-kinase given into rat hippocampus impairs acquisition, consolidation and retrieval of memory for one-trial step-down inhibitory avoidanceQ45714223
c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cellsQ56765298
P433issue1
P921main subjectG protein-coupled receptorQ38173
P304page(s)47-57
P577publication date2006-01-01
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleRole of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs
P478volume206

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cites work (P2860)
Q4002101617beta-estradiol attenuates glycogen synthase kinase-3beta activation and tau hyperphosphorylation in Akt-independent manner.
Q79896585Activation of epidermal growth factor receptor inhibits KCNQ2/3 current through two distinct pathways: membrane PtdIns(4,5)P2 hydrolysis and channel phosphorylation
Q34180196Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.
Q40085897Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury.
Q33492020Bovine sperm acrosome reaction induced by G-protein-coupled receptor agonists is mediated by epidermal growth factor receptor transactivation
Q54584247Differential involvement of phosphoinositide 3-kinase in gonadotrophin-releasing hormone actions in gonadotrophs and somatotrophs of goldfish, Carassius auratus.
Q40196818Differential reelin-induced enhancement of NMDA and AMPA receptor activity in the adult hippocampus.
Q39659975EGFR-mediated expression of aquaporin-3 is involved in human skin fibroblast migration
Q34908563Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30
Q34995542Esophageal cancer-related gene-4 (ECRG4) interactions with the innate immunity receptor complex
Q91523081Evidence for functional selectivity in TUDC- and norUDCA-induced signal transduction via α5β1 integrin towards choleresis
Q36976015G protein-coupled receptor-induced Akt activity in cellular proliferation and apoptosis.
Q37311388Gonadotropin-releasing hormone: GnRH receptor signaling in extrapituitary tissues.
Q39107808How is GnRH regulated in GnRH-producing neurons? Studies using GT1-7 cells as a GnRH-producing cell model
Q37184853Lysophosphatidic acid induces cell migration through the selective activation of Akt1.
Q42436722MEK1/2 differentially participates in GnRH actions on goldfish LH and GH secretion and hormone protein availability: acute and long-term effects, in vitro.
Q39246016Mechanisms of kringle fragment of urokinase-induced vascular smooth muscle cell migration
Q43006295Non-transactivational, dual pathways for LPA-induced Erk1/2 activation in primary cultures of brown pre-adipocytes
Q42456562PI3K signalling in GnRH actions on dispersed goldfish pituitary cells: relationship with PKC-mediated LH and GH release and regulation of long-term effects on secretion and total cellular hormone availability.
Q39117952Pituitary adenylate cyclase-activating polypeptide (PACAP) increases expression of the gonadotropin-releasing hormone (GnRH) receptor in GnRH-producing GT1-7 cells overexpressing PACAP type I receptor
Q37288005Signal transduction in multifactorial neuroendocrine control of gonadotropin secretion and synthesis in teleosts-studies on the goldfish model.
Q51372826Signaling events associated with gonadotropin releasing hormone-agonist-induced hormonal castration and its reversal in canines.
Q36195600Synergistic induction of cancer cell migration regulated by Gβγ and phosphatidylinositol 3-kinase
Q40309305The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex

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