Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

scientific article

Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.904601
P932PMC publication ID312750
P698PubMed publication ID11485993
P5875ResearchGate publication ID11857158

P2093author name stringB L Hogan
N R Dunn
K S Zaret
J M Rossi
P2860cites workThe Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4Q24315313
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4Q24554412
BMP4 is essential for lens induction in the mouse embryoQ24595509
Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heartQ24606117
Bmp4 is required for the generation of primordial germ cells in the mouse embryoQ24608134
Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouseQ28296363
Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroupQ28506935
Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formationQ28506952
Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth developmentQ28512639
Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac developmentQ28513337
GATA4 transcription factor is required for ventral morphogenesis and heart tube formationQ28586495
Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4Q28587988
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesisQ28592331
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenumQ29618151
Insulin-promoter-factor 1 is required for pancreas development in miceQ29619695
Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteinsQ33597105
Vertebrate endoderm developmentQ33804330
Positive and negative regulatory elements in the mouse albumin enhancerQ33840270
Liver specification and early morphogenesisQ33855384
Hepatic induction in the avian embryo: specificity of reactive endoderm and inductive mesodermQ34284367
An experimental analysis of liver developmentQ34303760
Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchymeQ35199256
Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm inductionQ35204526
Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitroQ36683946
Morphogenesis of digits in the avian limb is controlled by FGFs, TGFbetas, and noggin through BMP signalingQ39472922
FGF-4 and BMP-2 have opposite effects on limb growth.Q40869516
Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouseQ41161285
Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryosQ44061010
Neural induction by the secreted polypeptide nogginQ44628705
Induction across germ layers in Drosophila mediated by a genetic cascadeQ44630114
Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis.Q48038317
GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.Q48079082
GATA transcription factors as potentiators of gut endoderm differentiation.Q51093618
Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny.Q51128200
A bipotential precursor population for pancreas and liver within the embryonic endoderm.Q52139265
Repressive and restrictive mesodermal interactions with gut endoderm: possible relation to Meckel's Diverticulum.Q52163903
Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae.Q52177124
Morphogenesis.Q52179410
BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos.Q52189748
Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse.Q52192779
Differential expression of BMP receptors in early mouse development.Q52193152
The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis.Q52199809
Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control.Q52200970
Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.Q52204129
A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis.Q52447977
Hepatocyte differentiation initiates during endodermal-mesenchymal interactions prior to liver formation.Q54075246
Tissue interaction in chick liver development: a reevaluation. II. Parenchymal differentiation: mesenchymal influence and morphogenetic independenceQ67512840
Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic developmentQ69123971
Differentiation of the mouse hepatic primordium. I. An analysis of tissue interactions in hepatocyte differentiationQ71394127
Bone morphogenetic protein-9 binds to liver cells and stimulates proliferationQ72034641
Activin-A and FGF-2 mimic the inductive effects of anterior endoderm on terminal cardiac myogenesis in vitroQ72189395
Requirement for BMP and FGF signaling during cardiogenic induction in non-precardiac mesoderm is specific, transient, and cooperativeQ73864458
Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb budQ74326349
FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth developmentQ77350796
Promotion of the osteogenetic activity of recombinant human bone morphogenetic protein by basic fibroblast growth factorQ77760884
Initiation of mammalian liver development from endoderm by fibroblast growth factorsQ77894646
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)1998-2009
P577publication date2001-08-01
P1433published inGenes & DevelopmentQ1524533
P1476titleDistinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm
P478volume15

Reverse relations

cites work (P2860)
Q37057121A Case of Gastrointestinal Stromal Tumor That Underwent Endoscopic Ultrasound-Guided Aspiration with a 25-Gauge Biopsy Needle
Q38895292A Paracrine Mechanism Accelerating Expansion of Human Induced Pluripotent Stem Cell-Derived Hepatic Progenitor-Like Cells
Q50422444A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells.
Q42994112A circuit of paracrine signals between liver sinusoid endothelial cells and hepatocytes regulates hepatitis C virus replication
Q42505309A correlative study of the allantois in pig and rabbit highlighting the diversity of extraembryonic tissues in four mammalian species, including mouse and man.
Q36022695A crucial role of bone morphogenetic protein signaling in the wound healing response in acute liver injury induced by carbon tetrachloride
Q42125470A novel chemically directed route for the generation of definitive endoderm from human embryonic stem cells based on inhibition of GSK-3.
Q48343445A small-molecule screen reveals that HSP90β promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover
Q37696081Activation of GATA4 gene expression at the early stage of cardiac specification
Q37407147Activin A-induced differentiation of embryonic stem cells into endoderm and pancreatic progenitors-the influence of differentiation factors and culture conditions
Q92643993Adult and iPS-derived non-parenchymal cells regulate liver organoid development through differential modulation of Wnt and TGF-β
Q26769989Advances in Liver Regeneration: Revisiting Hepatic Stem/Progenitor Cells and Their Origin
Q36166139An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells
Q47073552An antiapoptotic role of sorting nexin 7 is required for liver development in zebrafish
Q34197939An endothelial cell niche induces hepatic specification through dual repression of Wnt and Notch signaling
Q28534882An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential
Q89514362Angiocrine endothelium: from physiology to cancer
Q34518370Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development
Q39684977Anterior-Posterior Patterning of Definitive Endoderm Generated from Human Embryonic Stem Cells Depends on the Differential Signaling of Retinoic Acid, Wnt-, and BMP-Signaling
Q52018698BMP is an important regulator of proepicardial identity in the chick embryo.
Q40211716BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm
Q52114639BMP4 modulates fibroblast growth factor-mediated induction of proximal and distal lung differentiation in mouse embryonic tracheal epithelium in mesenchyme-free culture.
Q84465271BMP7 can promote osteogenic differentiation of human periosteal cells in vitro
Q38837502BMP9-Induced Survival Effect in Liver Tumor Cells Requires p38MAPK Activation
Q38088672Beta cell dynamics: beta cell replenishment, beta cell compensation and diabetes.
Q34165885Beta-catenin signaling in hepatic development and progenitors: which way does the WNT blow?
Q36510510Biological principles for ex vivo adult stem cell expansion
Q38872219Blood vessel crosstalk during organogenesis-focus on pancreas and endothelial cells
Q38700736Bmp Signaling Governs Biliary-Driven Liver Regeneration in Zebrafish via Tbx2b and Id2a
Q43217501Bmp2 signaling regulates the hepatic versus pancreatic fate decision.
Q28510349Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis
Q40195822Bone morphogenetic protein-2 is a negative regulator of hepatocyte proliferation downregulated in the regenerating liver
Q51459998Bone morphogenetic protein-4 modulates proliferation and terminal differentiation of fetal hepatic stem/progenitor cells.
Q42044082C/EBPalpha and C/EBPbeta are markers of early liver development
Q36793453Cancer stem cells in the development of liver cancer
Q41216714Cancer stem cells: repair gone awry?
Q47376146Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage
Q30887216Cell-autonomous and signal-dependent expression of liver and intestine marker genes in pluripotent precursor cells from Xenopus embryos
Q26776328Cell-based therapies of liver diseases: age-related challenges
Q28750658Cell-cell signaling drives the evolution of complex traits: introduction-lung evo-devo
Q38110522Cellular and molecular basis of liver development.
Q37709553Cellular plasticity within the pancreas--lessons learned from development
Q36736868Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction
Q38007360Chromatin "pre-pattern" and epigenetic modulation in the cell fate choice of liver over pancreas in the endoderm
Q24297341Cited2, a coactivator of HNF4alpha, is essential for liver development
Q40068198Clonal, cultured, murine fetal liver hepatoblasts maintain liver specification in chimeric mice
Q92641939Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells
Q37355381Compensatory growth mechanisms regulated by BMP and FGF signaling mediate liver regeneration in zebrafish after partial hepatectomy
Q41885314Concurrent course of transient neonatal diabetes with cholestasis and paucity of interlobular bile ducts: a case report.
Q36903950Contribution of endothelial cells to organogenesis: a modern reappraisal of an old Aristotelian concept
Q33595592Contribution of hepatic lineage stage-specific donor memory to the differential potential of induced mouse pluripotent stem cells
Q37621220Converting human pluripotent stem cells into beta-cells: recent advances and future challenges
Q34991828Cytokine regulation of liver development
Q35140965Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures
Q38243677Derivation of Endodermal Progenitors From Pluripotent Stem Cells
Q34747011Development and diseases of the pancreas
Q37975904Development of the bile ducts: essentials for the clinical hepatologist
Q33282471Development of the mammalian liver and ventral pancreas is dependent on GATA4.
Q51902544Developmental Changes of Cell Adhesion Molecule Expression in the Fetal Mouse Liver
Q89599753Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cells
Q42177511Differential expression of natural antisense transcripts during liver development in embryonic mice
Q37853848Differentiating stem cells into liver.
Q37729855Differentiation of embryonic stem cells into hepatocytes that coexpress coagulation factors VIII and IX
Q41944061Differentiation of hepatocytes from pluripotent stem cells
Q34775617Differentiation of human embryonic stem cells along a hepatic lineage
Q52095740Differentiation of mouse embryonic stem cells into pancreatic and hepatic cells.
Q50471228Differentiation of nonhuman primate embryonic stem cells into hepatocyte-like cells.
Q43037453Directed differentiation of human embryonic stem cells into functional hepatic cells
Q37862139Directed hepatic differentiation from embryonic stem cells
Q28485172Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors
Q30977229Discovery of chicken microRNAs associated with lipogenesis and cell proliferation.
Q28586260Distinct roles for retinoic acid receptors alpha and beta in early lung morphogenesis
Q61448531Distinct roles of Dlk1 isoforms in bi-potential differentiation of hepatic stem cells
Q21146042Dorsoventral patterning in hemichordates: insights into early chordate evolution
Q42607239Dynamic signaling network for the specification of embryonic pancreas and liver progenitors
Q39038105Efficient generation of hepatic cells from multipotent adult mouse germ-line stem cells using an OP9 co-culture system
Q36102674Embryonic development of the liver
Q101216937Embryonic liver developmental trajectory revealed by single-cell RNA sequencing in the Foxa2eGFP mouse
Q38160150Endodermal and mesenchymal cross talk: a crossroad for the maturation of foregut organs
Q36889821Engraftment potential of spheroid-forming hepatic endoderm derived from human embryonic stem cells
Q35179363Enhanced differentiation of adult bone marrow-derived stem cells to liver lineage in aggregate culture
Q36432520Enhancement of hepatocyte differentiation from human embryonic stem cells by Chinese medicine Fuzhenghuayu
Q37272360Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development
Q33785831Essential role of BMPs in FGF-induced secondary lens fiber differentiation.
Q41856466Essential roles of zebrafish bmp2a, fgf10, and fgf24 in the specification of the ventral pancreas
Q36234228Establishment of a chick embryo model for analyzing liver development and a search for candidate genes
Q35417888Ethanol negatively regulates hepatic differentiation of hESC by inhibition of the MAPK/ERK signaling pathway in vitro
Q38844070Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment
Q36397956Extensive genetic variation in somatic human tissues
Q41592312Extracellular matrix microarrays to study inductive signaling for endoderm specification
Q64059879FGF signal is not required for hepatoblast differentiation of human iPS cells
Q46399626FGF signaling segregates biliary cell-lineage from chick hepatoblasts cooperatively with BMP4 and ECM components in vitro.
Q36406406FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1.
Q34236560Factors from human embryonic stem cell-derived fibroblast-like cells promote topology-dependent hepatic differentiation in primate embryonic and induced pluripotent stem cells
Q35098326Fibroblast growth factor enriches the embryonic liver cultures for hepatic progenitors
Q46047037Formation of the digestive system in zebrafish. I. Liver morphogenesis
Q35914420Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration
Q30485544Four-dimensional realistic modeling of pancreatic organogenesis
Q35029643From endoderm formation to liver and pancreas development in zebrafish
Q90577023Function of BMP4 in the Formation of Vasculogenic Mimicry in Hepatocellular Carcinoma
Q33355646GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos
Q28594766GATA4 is essential for formation of the proepicardium and regulates cardiogenesis
Q28508819GATA6 is essential for embryonic development of the liver but dispensable for early heart formation
Q38020117Generating cells of the gastrointestinal system: current approaches and applications for the differentiation of human pluripotent stem cells
Q37756278Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening
Q37341344Generation and regeneration of cells of the liver and pancreas
Q82478083Generation of Adipose Stromal Cell-Derived Hepatic Cells
Q38023060Generation of beta cells from human pluripotent stem cells: Potential for regenerative medicine
Q38264448Generation of functional hepatic cells from pluripotent stem cells
Q50500746Generation of functional hepatocyte-like cells from human deciduous periodontal ligament stem cells.
Q43243201Generation of homogeneous PDX1(+) pancreatic progenitors from human ES cell-derived endoderm cells
Q90639886Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions
Q33938401Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis
Q34768753Genetic programming of liver and pancreas progenitors: lessons for stem-cell differentiation
Q42775802Genomic integration of Wnt/β-catenin and BMP/Smad1 signaling coordinates foregut and hindgut transcriptional programs.
Q33239134Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression.
Q45950325Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells.
Q36967679Hedgehog signaling in development and homeostasis of the gastrointestinal tract
Q39255426Hepatic differentiation of human embryonic stem cells on growth factor-containing surfaces
Q34088893Hepatocyte differentiation: from the endoderm and beyond
Q36972087Hepatocyte polarity
Q28505706Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development
Q35192045High efficient differentiation of functional hepatocytes from porcine induced pluripotent stem cells
Q34157222Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
Q36376016Histology atlas of the developing mouse hepatobiliary system with emphasis on embryonic days 9.5-18.5.
Q33658734Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells
Q52658323Human pluripotent stem cell derived HLC transcriptome data enables molecular dissection of hepatogenesis.
Q33856252Hypoxia-inducible factor 2 alpha is essential for hepatic outgrowth and functions via the regulation of leg1 transcription in the zebrafish embryo
Q40891867Id2a is required for hepatic outgrowth during liver development in zebrafish.
Q39832111Identification of an ancient Bmp4 mesoderm enhancer located 46 kb from the promoter
Q41694163Identification of hub genes involved in the development of hepatocellular carcinoma by transcriptome sequencing
Q81344210Immunohistochemical analyses of cell-cell interactions during hepatic organoid formation from fetal mouse liver cells cultured in vitro
Q44462975Immunohistochemical localization of nanog and Oct4 in stem cell compartments of human sacrococcygeal teratomas
Q42467548Immunolocalization of extracellular matrix components and integrins during mouse liver development
Q44547162Impaired differentiation of fetal hepatocytes in homozygous jumonji mice
Q38062883Implication of hepatic stem cells in functional liver repopulation
Q75209471In vitro differentiation of embryonic stem cells into hepatocytes
Q37790656Inducing the liver: Understanding the signals that promote murine liver budding
Q39106301Induction of Pax3 gene expression impedes cardiac differentiation.
Q52101039Induction of hepatic differentiation in embryonic stem cells by co-culture with embryonic cardiac mesoderm.
Q90685529Intriguing Roles for Endothelial ADAM10/Notch Signaling in the Development of Organ-Specific Vascular Beds
Q38291493Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development
Q81319033Kinetics of albumin- and alpha-fetoprotein-production during rat liver development
Q64062739Liver Specification in the Absence of Cardiac Differentiation Revealed by Differential Sensitivity to Wnt/β Catenin Pathway Activation
Q37524738Liver development in zebrafish (Danio rerio).
Q37695098Liver development, regeneration, and carcinogenesis
Q91841337Liver diseases in the dish: iPSC and organoids as a new approach to modeling liver diseases
Q37358938Liver stem cells and hepatocellular carcinoma
Q43148137Liver stem cells and molecular signaling pathways in hepatocellular carcinoma
Q36382298Liver stem cells and prospects for liver reconstitution by transplanted cells
Q37827017Liver stem/progenitor cells: their characteristics and regulatory mechanisms
Q35930935Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish
Q39196881Making It New Again: Insight Into Liver Development, Regeneration, and Disease From Zebrafish Research
Q33518508Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish
Q39151720Mechanisms of embryonic stomach development
Q43811728Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts
Q45995605Mesodermal Wnt2b signalling positively regulates liver specification.
Q38038648MicroRNAs in pancreas development
Q33932547Microarray comparison of the gene expression profiles in the adult vs. embryonic day 14 rat liver
Q104130449Midline morphogenesis of zebrafish foregut endoderm is dependent on Hoxb5b
Q28585145Mind bomb 1 is required for pancreatic β-cell formation
Q37676601Model systems and experimental conditions that lead to effective repopulation of the liver by transplanted cells
Q36787582Molecular mechanism of liver development and regeneration
Q38116918Molecular mechanisms of liver and bile duct development
Q38022406Molecular pathways controlling pancreas induction
Q91854141Molecular regulation of mammalian hepatic architecture
Q38553312Morphogen-related therapeutic targets for liver fibrosis
Q43102632Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation
Q28591482Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos
Q36730975Multiple roles for Med12 in vertebrate endoderm development.
Q28585515Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression
Q91203079Mypt1 regulates Bmp signaling to promote embryonic exocrine pancreas growth in zebrafish
Q41542898Mypt1-mediated spatial positioning of Bmp2-producing cells is essential for liver organogenesis
Q37366907NFAT4 deficiency results in incomplete liver regeneration following partial hepatectomy
Q30499859Neuron navigator 3a regulates liver organogenesis during zebrafish embryogenesis.
Q40131672Neurturin-GFRalpha2 signaling controls liver bud migration along the ductus venosus in the chick embryo.
Q53509563New primary culture systems to study the differentiation and proliferation of mouse fetal hepatoblasts.
Q34998404New school in liver development: lessons from zebrafish
Q92542959Next-Generation Liver Medicine Using Organoid Models
Q37234161On the origin of the beta cell
Q37986563Ontogenesis of hepatic and pancreatic stem cells
Q35791195Orchestrating liver development
Q38197503Orchestration of hepatocellular carcinoma development by diverse liver cancer stem cells
Q38882518Organoids from adult liver and pancreas: Stem cell biology and biomedical utility
Q37596305Pancreas cell fate
Q37845287Pancreas organogenesis: from bud to plexus to gland
Q38843538Paracrine signals from liver sinusoidal endothelium regulate hepatitis C virus replication
Q47218053Patterning of the hepato-pancreatobiliary boundary by BMP reveals heterogeneity within the murine liver bud.
Q34850028Pediatric liver tumors and hepatic ontogenesis: common and distinctive pathways
Q37333323Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm
Q51843012Precocious expression of cardiac troponin T in early chick embryos is independent of bone morphogenetic protein signaling.
Q39640477Production of Functional Glucagon-Secreting α-Cells From Human Embryonic Stem Cells
Q35018029Progenitor cells of the biliary epithelial cell lineage
Q51852702Progress in stem cell biology in regenerative medicine for liver disease.
Q34417663Prolonged FGF signaling is necessary for lung and liver induction in Xenopus
Q41529199Proper BMP Signaling Levels Are Essential for 3D Assembly of Hepatic Cords from Hepatoblasts and Mesenchymal Cells.
Q51953700Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts.
Q37735157Prostaglandin E2 regulates liver versus pancreas cell-fate decisions and endodermal outgrowth.
Q44154968Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm
Q36969132Rargb regulates organ laterality in a zebrafish model of right atrial isomerism.
Q50628619Real time monitoring of BMP Smads transcriptional activity during mouse development.
Q37878871Recent advances in stem cell research for the treatment of diabetes
Q26825664Recent developments in β-cell differentiation of pluripotent stem cells induced by small and large molecules
Q39136966Regenerative Medicine and the Biliary Tree
Q47824547Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling.
Q24307591Regulation of Hex gene expression by a Smads-dependent signaling pathway
Q34718150Regulatory phases of early liver development: paradigms of organogenesis
Q42073503Restriction of hepatic competence by Fgf signaling
Q28511721Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives
Q45029443Retinoic acid selectively regulates Fgf10 expression and maintains cell identity in the prospective lung field of the developing foregut
Q44936362Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus
Q33466026Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis
Q44408462Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells
Q92542899Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury
Q35029661Role of endothelial cells in early pancreas and liver development
Q50788157Simulated microgravity promoted differentiation of bipotential murine oval liver stem cells by modulating BMP4/Notch1 signaling.
Q90671502Single-cell transcriptomic analyses reveal distinct dorsal/ventral pancreatic programs
Q39556581Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling
Q37764509Smooth muscle differentiation and patterning in the urinary bladder
Q39602274Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.
Q34626511Stem cells in the adult pancreas and liver
Q33801245Stem cells, cell transplantation and liver repopulation
Q33666887Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic beta-cells in zebrafish
Q26821978Targeting the Wnt pathways for therapies
Q51891763The "self-similarity logic" applied to the development of the vascular system.
Q37677914The Fox genes in the liver: from organogenesis to functional integration
Q34723542The GATA family (vertebrates and invertebrates).
Q28513470The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration
Q28066412The Role of Mesothelial Cells in Liver Development, Injury, and Regeneration
Q50559743The advancement of human pluripotent stem cell-derived therapies into the clinic.
Q34287984The existence of multipotent stem cells with epithelial-mesenchymal transition features in the human liver bud.
Q48275367The fate of the vitelline and umbilical veins during the development of the human liver
Q39753807The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm
Q33967786The mitochondrial import gene tomm22 is specifically required for hepatocyte survival and provides a liver regeneration model
Q36234233The molecular basis and prospects in pancreatic development
Q38140492The road to regenerative liver therapies: the triumphs, trials and tribulations
Q37769458The role of mesodermal signals during liver organogenesis in zebrafish
Q34565292The role of progenitor cells in repair of liver injury and in liver transplantation
Q42175777The septum transversum mesenchyme induces gall bladder development
Q57150366The use of human pluripotent stem cells for modelling liver development and disease
Q51987715Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation.
Q40488366Transcription factor HNF-6/OC-1 inhibits the stimulation of the HNF-3alpha/Foxa1 gene by TGF-beta in mouse liver
Q28212211Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6
Q37130245Transcriptional dynamics of endodermal organ formation
Q35857682Transcriptional networks controlling pancreatic development and beta cell function.
Q38041096Transcriptional networks in liver and intestinal development
Q36025249Transdetermination: Drosophila imaginal disc cells exhibit stem cell-like potency
Q35029684Transdifferentiation of pancreas to liver
Q51130201Two populations of Thy1-positive mesenchymal cells regulate in vitro maturation of hepatic progenitor cells.
Q38025328Understanding pancreas development for β-cell repair and replacement therapies
Q38548499Unique functions of Gata4 in mouse liver induction and heart development
Q34209343Using growth factor arrays and micropatterned co-cultures to induce hepatic differentiation of embryonic stem cells
Q38544161Using stem cells to produce insulin
Q28589718VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis
Q34816724Vertebrate intestinal endoderm development
Q35132288Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development
Q42652916Wnt signaling in gut organogenesis
Q37080175Wnt/beta-catenin signaling in hepatic organogenesis
Q50070375Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology
Q41985671Wnt/β-catenin signaling cell-autonomously converts non-hepatic endodermal cells to a liver fate
Q38290485Wnt9a secreted from the walls of hepatic sinusoids is essential for morphogenesis, proliferation, and glycogen accumulation of chick hepatic epithelium
Q79671104Zebrafish and the understanding of liver development: the emerging role of the Wnt pathway in liver biology
Q36669372Zebrafish models of human liver development and disease
Q28178146c-jun regulation and function in the developing hindbrain

Search more.