Cancer stem cells in the development of liver cancer

scientific article published on May 2013

Cancer stem cells in the development of liver cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI66024
P932PMC publication ID3635728
P698PubMed publication ID23635789

P2093author name stringXin Wei Wang
Taro Yamashita
P2860cites workGlobal cancer statisticsQ22241238
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BMP4 administration induces differentiation of CD133+ hepatic cancer stem cells, blocking their contributions to hepatocellular carcinoma.Q54498797
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Human hepatic stem-like cells isolated using c-kit or CD34 can differentiate into biliary epitheliumQ73400327
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EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell featuresQ30493364
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Association of TP53 mutations with stem cell-like gene expression and survival of patients with hepatocellular carcinoma.Q34672668
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Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.Q34798776
Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells?Q34988085
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Cellular origin of hepatocellular carcinomasQ35018040
Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3Q35101216
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.Q35237526
Epithelial cell adhesion molecule (EpCAM) complex proteins promote transcription factor-mediated pluripotency reprogrammingQ35312062
Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenograftsQ35531664
CD24-positive cells from normal adult mouse liver are hepatocyte progenitor cellsQ35575805
Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 lossQ35613285
Transdifferentiation of rat hepatocytes into biliary cells after bile duct ligation and toxic biliary injuryQ35677684
Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in cultureQ35713428
Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytesQ35764088
Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.Q35823178
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Cholangiocarcinomas can originate from hepatocytes in miceQ36129118
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TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma.Q36237549
Temporal changes in PTEN and mTORC2 regulation of hematopoietic stem cell self-renewal and leukemia suppressionQ36248716
Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinomaQ36279142
Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in miceQ36421780
Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signalingQ36497297
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinomaQ36547263
Hepatitis B virus integration, fragile sites, and hepatocarcinogenesisQ36692164
TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancerQ36777331
WNT/beta-catenin signaling in liver health and diseaseQ36804161
Liver cancer stem cellsQ36835025
Mechanisms of hepatocyte growth factor-mediated and epidermal growth factor-mediated signaling in transdifferentiation of rat hepatocytes to biliary epitheliumQ37041709
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinomaQ37284612
Liver stem cells and hepatocellular carcinomaQ37358938
The role of signaling pathways in the development and treatment of hepatocellular carcinomaQ37773788
Discrete nature of EpCAM+ and CD90+ cancer stem cells in human hepatocellular carcinomaQ39240497
OV6⁺ tumor-initiating cells contribute to tumor progression and invasion in human hepatocellular carcinomaQ39345207
DLK1 as a potential target against cancer stem/progenitor cells of hepatocellular carcinomaQ39413382
CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signalingQ39459026
CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulationQ39512947
Role of Sox2 and Oct4 in predicting survival of hepatocellular carcinoma patients after hepatectomy.Q39581200
Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.Q39592731
miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.Q39626637
Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulationQ39639351
Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiationQ39702464
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectliver cancerQ623031
neoplastic stem cellsQ1638475
P304page(s)1911-1918
P577publication date2013-05-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleCancer stem cells in the development of liver cancer
P478volume123