| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1994PNAS...91.2230W |
| P356 | DOI | 10.1073/PNAS.91.6.2230 |
| P932 | PMC publication ID | 43344 |
| P698 | PubMed publication ID | 8134379 |
| P5875 | ResearchGate publication ID | 15065633 |
| P2093 | author name string | Harris CC | |
| Gu JR | |||
| Wang XW | |||
| Forrester K | |||
| Feitelson MA | |||
| Yeh H | |||
| P2860 | cites work | Wild-type p53 binds to the TATA-binding protein and represses transcription | Q24300991 |
| A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome | Q24306514 | ||
| The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Q24319848 | ||
| Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase | Q27860571 | ||
| WAF1, a potential mediator of p53 tumor suppression | Q27861121 | ||
| Oncogenic forms of p53 inhibit p53-regulated gene expression | Q28251120 | ||
| Amplification of a gene encoding a p53-associated protein in human sarcomas | Q28270924 | ||
| The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation | Q28280958 | ||
| Identification of p53 as a sequence-specific DNA-binding protein | Q28282745 | ||
| p53 mutations in human cancers | Q28302973 | ||
| A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia | Q29615437 | ||
| T antigen is bound to a host protein in SY40-transformed cells | Q29618321 | ||
| The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product | Q29618372 | ||
| DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor | Q29619833 | ||
| Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan | Q34054719 | ||
| Expression of the hepatitis B virus X gene in mammalian cells | Q34615411 | ||
| A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18 | Q35937193 | ||
| Simian virus 40 large tumor antigen-immortalized normal human liver epithelial cells express hepatocyte characteristics and metabolize chemical carcinogens | Q36338389 | ||
| EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins. | Q36358319 | ||
| Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases. | Q36508624 | ||
| Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. | Q36660357 | ||
| The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription | Q36685220 | ||
| Inhibition of DNA replication factor RPA by p53. | Q36768122 | ||
| Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1 | Q36920336 | ||
| Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway | Q38321449 | ||
| Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C | Q40064034 | ||
| Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells | Q40237209 | ||
| Clinical implications of the p53 tumor-suppressor gene | Q40865658 | ||
| Malignant transformation of immortalized transgenic hepatocytes after transfection with hepatitis B virus DNA | Q41206745 | ||
| The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element. | Q41213854 | ||
| p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines | Q41556197 | ||
| Gain of function mutations in p53. | Q41557652 | ||
| In vitro tumorigenicity of hepatitis B virus DNA and HBx protein | Q41705071 | ||
| HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions | Q44489320 | ||
| The X gene of hepatitis B virus induced growth stimulation and tumorigenic transformation of mouse NIH3T3 cells | Q45166424 | ||
| The hepatitis B virus-encoded transcriptional trans-activator hbx appears to be a novel protein serine/threonine kinase | Q45850090 | ||
| HBx gene of hepatitis B virus induces liver cancer in transgenic mice | Q45852802 | ||
| Stranded in an active gene | Q46181255 | ||
| Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa | Q46754150 | ||
| Diversity of human p53 mutants revealed by complex formation to SV40 T antigen | Q46797328 | ||
| The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen | Q46840212 | ||
| Mutational hot spot in the p53 gene in human hepatocellular carcinomas | Q53499208 | ||
| Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene. | Q53551443 | ||
| DNA repair and transcription: the helicase connection. | Q54659177 | ||
| Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells | Q64381309 | ||
| Different tumor-derived p53 mutants exhibit distinct biological activities | Q68568861 | ||
| Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription | Q70760070 | ||
| Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma | Q72966947 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Hepatitis B virus | Q6844 |
| hepatitis B | Q6853 | ||
| P304 | page(s) | 2230-2234 | |
| P577 | publication date | 1994-03-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3 | |
| P478 | volume | 91 |
| Q38485282 | A comprehensive karyotypic analysis on Korean hepatocellular carcinoma cell lines by cross-species color banding and comparative genomic hybridization |
| Q37068909 | A novel mutant 10Ala/Arg together with mutant 144Ser/Arg of hepatitis B virus X protein involved in hepatitis B virus-related hepatocarcinogenesis in HepG2 cell lines |
| Q43034453 | A p53 polymorphism associated with increased risk of hepatitis C virus infection |
| Q30454445 | A p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells |
| Q37594965 | A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function |
| Q40806214 | Accumulation of wild-type p53 protein upon gamma-irradiation induces a G2 arrest-dependent immunoglobulin kappa light chain gene expression. |
| Q36573498 | Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras |
| Q48031361 | Adaptive response to DNA-damaging agents: a review of potential mechanisms |
| Q39578554 | Adenovirus type 12-induced fragility of the human RNU2 locus requires p53 function. |
| Q36560030 | Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein |
| Q34302134 | Altered proteolysis and global gene expression in hepatitis B virus X transgenic mouse liver |
| Q40321521 | An intact sequence-specific DNA-binding domain is required for human cytomegalovirus-mediated sequestration of p53 and may promote in vivo binding to the viral genome during infection |
| Q38297491 | An internal segment (residues 58-119) of the hepatitis B virus X protein is sufficient to activate MAP kinase pathways in mouse liver |
| Q33391857 | An international, multicenter phase II trial of bortezomib in patients with hepatocellular carcinoma. |
| Q37092920 | An overview of molecular epidemiology of hepatitis B virus (HBV) in India |
| Q38515827 | An overview of new biomolecular pathways in pathogen-related cancers |
| Q41732079 | Apoptosis in neurological disease |
| Q39873599 | Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis, and is blocked by insulin-like growth factor II. |
| Q41515231 | Apoptosis: an overview of the process and its relevance in disease. |
| Q26782217 | Association of Lymphomagenesis and the Reactivation of Hepatitis B Virus in Non-Hodgkin Lymphoma |
| Q38388893 | At a crossroads: human DNA tumor viruses and the host DNA damage response. |
| Q39549322 | Baculovirus p33 binds human p53 and enhances p53-mediated apoptosis. |
| Q35788005 | Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection |
| Q36793453 | Cancer stem cells in the development of liver cancer |
| Q30860353 | Cell-specific modulation of papovavirus replication by tumor suppressor protein p53 |
| Q41175577 | Cervical neoplasia. Pathogenesis, diagnosis, and management |
| Q42021790 | Characterization of six tumor suppressor genes and microsatellite instability in hepatocellular carcinoma in southern African blacks |
| Q40844117 | Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells |
| Q41348469 | Classical swine fever virus Shimen infection increases p53 signaling to promote cell cycle arrest in porcine alveolar macrophages |
| Q32077516 | Cloning of a cDNA from Arabidopsis thaliana homologous to the human XPB gene. |
| Q42010880 | Cloning of differentially expressed genes in human hepatocellular carcinoma and nontumor liver. |
| Q46967691 | Comparison of surgical outcomes for small hepatocellular carcinoma in patients with hepatitis B versus hepatitis C: a Chinese experience. |
| Q74456043 | Compensatory apoptosis in preneoplastic liver of a transgenic mouse model for viral hepatocarcinogenesis |
| Q36415580 | Construction of eukaryotic expression vector of HBV x gene |
| Q45730394 | Correlation of clinical characteristics with detection of hepatitis B virus X gene in liver tissue in HBsAg-negative, and HCV-negative hepatocellular carcinoma patients |
| Q24301537 | Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor |
| Q36557538 | Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage |
| Q37088586 | Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide |
| Q39604717 | DDB2 induces nuclear accumulation of the hepatitis B virus X protein independently of binding to DDB1. |
| Q36430931 | DDP-induced cytotoxicity is not influenced by p53 in nine human ovarian cancer cell lines with different p53 status. |
| Q44365341 | DEN+2-AAF-induced multistep hepatotumorigenesis in Wistar rats: supportive evidence and insights |
| Q42816808 | DNA damage induced p53 stabilization: no indication for an involvement of p53 phosphorylation |
| Q43119157 | DNA methylation and carcinogenesis in digestive neoplasms. |
| Q40768679 | DNA repair is activated in early stages of p53-induced apoptosis |
| Q42828172 | Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice |
| Q52538684 | Decreased DNA repair efficiency by loss or disruption of p53 function preferentially affects removal of cyclobutane pyrimidine dimers from non-transcribed strand and slow repair sites in transcribed strand. |
| Q37372165 | Deregulated direct targets of the hepatitis B virus (HBV) protein, HBx, identified through chromatin immunoprecipitation and expression microarray profiling |
| Q35565676 | Detection of hypermethylation of the p16(INK4A) gene promoter in chronic hepatitis and cirrhosis associated with hepatitis B or C virus |
| Q40238869 | Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein |
| Q43119119 | Differentially expressed genes in hepatocellular carcinoma induced by woodchuck hepatitis B virus in mice. |
| Q42436644 | Differentiation-dependent p53 regulation of nucleotide excision repair in keratinocytes |
| Q35835238 | Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation |
| Q77844569 | Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery |
| Q42478545 | Disruption of the function of tumor-suppressor gene p53 by the hepatitis B virus X protein and hepatocarcinogenesis |
| Q40794517 | Distinctive gene expression profiles associated with Hepatitis B virus x protein |
| Q37034967 | Divergent viral presentation among human tumors and adjacent normal tissues. |
| Q40962782 | Downregulation of DNA excision repair by the hepatitis B virus-x protein occurs in p53-proficient and p53-deficient cells |
| Q45423109 | Downregulation of E-cadherin by hepatitis B virus X antigen in hepatocellullar carcinoma |
| Q35737349 | Early molecular and genetic determinants of primary liver malignancy |
| Q28273926 | Effect of transforming viruses on molecular mechanisms associated with cancer |
| Q36498665 | Effects of Pseudorabies Virus Infection on the Tracheobronchial Lymph Node Transcriptome |
| Q40711048 | Efficient repair of bulky anti-BPDE DNA adducts from non-transcribed DNA strand requires functional p53 but not p21(waf1/cip1) and pRb. |
| Q35990415 | Enhancement of gene transactivation activity of androgen receptor by hepatitis B virus X protein |
| Q34970818 | Enhancement of hepatitis B virus replication by its X protein in transgenic mice |
| Q34872837 | Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities |
| Q34720551 | Excision Repair in Mammalian Cells |
| Q45748434 | Expression of fas ligand in human hepatoma cell lines: role of hepatitis-B virus X (HBX) in induction of Fas ligand |
| Q33787132 | Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice |
| Q43857388 | Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas |
| Q58695696 | Foot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression |
| Q34389709 | From chronic liver disorders to hepatocellular carcinoma: Molecular and genetic pathways |
| Q38300638 | Functional inactivation but not structural mutation of p53 causes liver cancer. |
| Q24290998 | Functional inactivation of p73, a homolog of p53 tumor suppressor protein, by human papillomavirus E6 proteins |
| Q36561445 | Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo. |
| Q35847090 | Functional interactions between p53 and the TFIIH complex are affected by tumour-associated mutations |
| Q34968621 | Fuse binding protein antagonizes the transcription activity of tumor suppressor protein p53. |
| Q36150432 | Gene- and immunotherapy for hepatocellular carcinoma |
| Q36129235 | Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors |
| Q34611410 | Genetic mechanisms of hepatocarcinogenesis |
| Q80353336 | Genetics of hepatocellular carcinoma |
| Q42061657 | Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein |
| Q73283449 | HBV transcription repression in response to genotoxic stress is p53-dependent and abrogated by pX |
| Q38333320 | HBx protein of hepatitis B virus activates Jak1-STAT signaling |
| Q38840132 | HBx triggers either cellular senescence or cell proliferation depending on cellular phenotype |
| Q40720204 | HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis |
| Q38922362 | Hepatitis B Virus Core Promoter A1762T/G1764A (TA)/T1753A/T1768A Mutations Contribute to Hepatocarcinogenesis by Deregulating Skp2 and P53. |
| Q71498810 | Hepatitis B and C viruses and hepatocellular carcinoma |
| Q33765576 | Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls |
| Q27485874 | Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha |
| Q35764338 | Hepatitis B virus X antigen in the pathogenesis of chronic infections and the development of hepatocellular carcinoma |
| Q37885837 | Hepatitis B virus X gene and hepatocarcinogenesis. |
| Q40794530 | Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis |
| Q45747173 | Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx. |
| Q39605979 | Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions |
| Q36830710 | Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis |
| Q34666783 | Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cells |
| Q44509761 | Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway |
| Q33837409 | Hepatitis B virus X protein impedes the DNA repair via its association with transcription factor, TFIIH |
| Q36573780 | Hepatitis B virus X protein induces RNA polymerase III-dependent gene transcription and increases cellular TATA-binding protein by activating the Ras signaling pathway |
| Q24676695 | Hepatitis B virus X protein interacts with a probable cellular DNA repair protein |
| Q33781959 | Hepatitis B virus X protein interferes with cellular DNA repair. |
| Q45764450 | Hepatitis B virus X protein is a transcriptional modulator that communicates with transcription factor IIB and the RNA polymerase II subunit 5. |
| Q33649039 | Hepatitis B virus X protein is both a substrate and a potential inhibitor of the proteasome complex |
| Q37172987 | Hepatitis B virus X protein mediated suppression of miRNA-122 expression enhances hepatoblastoma cell proliferation through cyclin G1-p53 axis |
| Q38345616 | Hepatitis B virus X protein modulates peroxisome proliferator-activated receptor gamma through protein-protein interaction. |
| Q37621008 | Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis |
| Q40399517 | Hepatitis B virus X protein represses E-cadherin expression via activation of DNA methyltransferase 1. |
| Q39645695 | Hepatitis B virus X protein stimulates IL-6 expression in hepatocytes via a MyD88-dependent pathway |
| Q34308890 | Hepatitis B virus and hepatocellular carcinoma |
| Q45406149 | Hepatitis B virus and intrahepatic cholangiocarcinoma |
| Q33855246 | Hepatitis B virus biology |
| Q24292159 | Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription |
| Q39574625 | Hepatitis B virus pX targets TFIIB in transcription coactivation |
| Q34673509 | Hepatitis B virus transactivator protein X interacts with the TATA-binding protein. |
| Q28573627 | Hepatitis B virus transactivator protein, HBx, associates with the components of TFIIH and stimulates the DNA helicase activity of TFIIH |
| Q41167238 | Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis |
| Q27024874 | Hepatitis B virus, HBx mutants and their role in hepatocellular carcinoma |
| Q22254707 | Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells |
| Q45741819 | Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis |
| Q43601401 | Hepatitis B x protein inhibits p53-dependent DNA repair in primary mouse hepatocytes |
| Q24682883 | Hepatitis Bx antigen stimulates expression of a novel cellular gene, URG4, that promotes hepatocellular growth and survival |
| Q28569202 | Hepatitis C virus NS5A protein binds TBP and p53, inhibiting their DNA binding and p53 interactions with TBP and ERCC3 |
| Q33516543 | Hepatitis C-associated hepatocellular carcinomas in non-cirrhotic livers |
| Q80974190 | Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma |
| Q33601735 | Hepatocellular carcinoma |
| Q45387844 | Hepatocellular carcinoma (HCC) recurring 10 years after clearance of hepatitis B surface antigen and 20 years after resection of hepatitis B virus-related HCC. |
| Q27489394 | Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis |
| Q35193283 | Hepatocellular carcinoma: are we making progress? |
| Q37888329 | Hepatocellular carcinoma: the point of view of the hepatitis B virus |
| Q36667622 | Hot-spot p53 mutants interact specifically with two cellular proteins during progression of the cell cycle |
| Q24338043 | Human S15a expression is upregulated by hepatitis B virus X protein |
| Q35873729 | Human cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription |
| Q45749779 | Human hepatitis B virus X protein augments the DNA binding of nuclear factor for IL-6 through its basic-leucine zipper domain |
| Q30658556 | Human hepatitis B virus X protein is detectable in nuclei of transfected cells, and is active for transactivation |
| Q40922670 | Human mammary epithelial cells exhibit a differential p53-mediated response following exposure to ionizing radiation or UV light |
| Q43862472 | Human urinary bladder epithelial cells lacking wild-type p53 function are deficient in the repair of 4-aminobiphenyl-DNA adducts in genomic DNA. |
| Q37009862 | Hypoxia inducible factor (HIF) function in innate immunity and infection |
| Q24633776 | Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach |
| Q32151473 | Identification of a protein isolated from senescent human cells that binds to hepatitis B virus X antigen |
| Q39937625 | Identification of functionally important amino acid residues in the mitochondria targeting sequence of hepatitis B virus X protein. |
| Q36401448 | Immune pathogenesis of hepatocellular carcinoma. |
| Q35773554 | Immunihistochemical detection of Bcl-2 in AIDS-associated and classical Kaposi's sarcoma. |
| Q43641235 | Immunohistochemical assessment and prognostic value of hepatitis B virus X protein in chronic hepatitis and primary hepatocellular carcinomas using anti-HBxAg monoclonal antibody |
| Q34534264 | Immunotherapy of hepatocellular carcinoma |
| Q37604165 | Impact of hepatitis B virus X protein on the DNA damage response during hepatocarcinogenesis |
| Q36006754 | Impact of transforming viruses on cellular mutagenesis, genome stability, and cellular transformation |
| Q42220062 | Impact of viral hepatitis on outcomes after liver resection for hepatocellular carcinoma: results from a north american center. |
| Q40912156 | Impaired nucleotide excision repair in UV-irradiated human oral keratinocytes immortalized with type 16 human papillomavirus genome |
| Q57998104 | Implicación de la proteína HBx del virus de la hepatitis B en la respuesta inmune y la progresión tumoral |
| Q39873297 | In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes |
| Q33963311 | Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation. |
| Q38527672 | Incidence of hepatocellular carcinoma in transgenic mice expressing the hepatitis B virus X-protein |
| Q45731365 | Increased chromosomal alterations and micronuclei formation in human hepatoma HepG2 cells transfected with the hepatitis B virus HBX gene |
| Q45770734 | Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene |
| Q37897153 | Infiltrating hepatocellular carcinoma: seeing the tree through the forest |
| Q40953393 | Influence of p53 tumor suppressor protein on bias of DNA repair and apoptotic response in human cells |
| Q37423197 | Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner |
| Q34082379 | Interaction of Hepatitis B virus with cellular processes in liver carcinogenesis |
| Q77896896 | Interaction of hepatitis B viral X protein and CCAAT/ enhancer-binding protein alpha synergistically activates the hepatitis B viral enhancer II/pregenomic promoter |
| Q39570667 | Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival |
| Q24309466 | Interaction of p53 with the human Rad51 protein |
| Q35890510 | Interaction of the UV-damaged DNA-binding protein with hepatitis B virus X protein is conserved among mammalian hepadnaviruses and restricted to transactivation-proficient X-insertion mutants |
| Q43565298 | Interaction of the hepatitis B virus X protein with the Crm1-dependent nuclear export pathway |
| Q33292428 | Interaction of the hepatitis B virus protein HBx with the human transcription regulatory protein p120E4F in vitro |
| Q40937852 | Interactions between alcohol and hepatitis viruses in the liver. |
| Q42818894 | Intermolecular phosphorylation between insulin holoreceptors does not stimulate substrate kinase activity |
| Q33616812 | Involvement of DNA damage response pathways in hepatocellular carcinoma |
| Q41592444 | Involvement of p53 in cell differentiation and development |
| Q38563753 | Lessons from the p53 mutant mouse |
| Q33934051 | Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance |
| Q47672507 | Liver regeneration, liver cancers and cyclins |
| Q47791939 | Liver-specific enhancer II is the target for the p53-mediated inhibition of hepatitis B viral gene expression |
| Q55263081 | Localization of a target region of allelic loss to a 1-cM interval on chromosome 16p.13.13 in hepatocellular carcinoma. |
| Q36586442 | Loss of the gene encoding mannose 6-phosphate/insulin-like growth factor II receptor is an early event in liver carcinogenesis |
| Q52340395 | MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options? |
| Q44195400 | Mechanisms for inhibition of hepatitis B virus gene expression and replication by hepatitis C virus core protein. |
| Q39582296 | Metabolic labeling of woodchuck hepatitis B virus X protein in naturally infected hepatocytes reveals a bimodal half-life and association with the nuclear framework. |
| Q45736340 | Microinjection technique used to study functional interaction between p53 and hepatitis B virus X gene in apoptosis |
| Q36226733 | Mitochondria as functional targets of proteins coded by human tumor viruses |
| Q39528901 | Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress |
| Q34821616 | Modeling hepatitis B virus X-induced hepatocellular carcinoma in mice with the Sleeping Beauty transposon system. |
| Q26825783 | Modulation of DNA damage and repair pathways by human tumour viruses |
| Q36432730 | Modulation of apoptotic signaling by the hepatitis B virus X protein |
| Q45741117 | Modulation of glutathione S-transferase alpha by hepatitis B virus and the chemopreventive drug oltipraz |
| Q71743093 | Modulation of interleukin-6-induced plasma protein secretion in hepatoma cells by p53 species |
| Q40532008 | Modulation of p53 cellular function and cell death by African swine fever virus |
| Q35048768 | Molecular carcinogenesis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: one step closer to personalized medicine? |
| Q34639833 | Molecular epidemiology in environmental health: the potential of tumor suppressor gene p53 as a biomarker |
| Q41073230 | Molecular mechanisms of virus-induced carcinogenesis: the interaction of viral factors with cellular tumor suppressor proteins |
| Q27686923 | Molecular mechanisms underlying occult hepatitis B virus infection |
| Q34167480 | Molecular pathogenesis of human hepatocellular carcinoma. |
| Q41101450 | Molecular variants of hepatitis B virus. |
| Q36282234 | Molecular virology of hepatitis B virus for clinicians |
| Q43988430 | Molecular, immunological and clinical properties of mutated hepatitis B viruses. |
| Q52834192 | Mutation of p53 gene in hepatocellular carcinoma cell lines with HBX DNA. |
| Q74485505 | Mutation of p53 gene in regenerative nodules in cirrhotic liver |
| Q33833014 | Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin-dependent kinase inhibitor p21 gene |
| Q40789361 | Negative feedback regulation of wild-type p53 biosynthesis. |
| Q34047246 | New insights into p53 regulation and gene therapy for cancer. |
| Q39018547 | New potential instrument to fight hepatocellular cancer by restoring p53 |
| Q37694644 | Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. |
| Q64056509 | Nucleoporin Nup155 is part of the p53 network in liver cancer |
| Q33404215 | Other proteins interacting with XP proteins |
| Q42558183 | Oxidative stress and antioxidants in hepatic pathogenesis |
| Q40859958 | P53 but not p16INK4a induces growth arrest in retinoblastoma-deficient hepatocellular carcinoma cells. |
| Q34068117 | Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesis |
| Q28284012 | Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma |
| Q40243174 | Potential role for p53 in the permissive life cycle of human cytomegalovirus |
| Q38355045 | Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal |
| Q46409564 | Proneness to UV-induced apoptosis in human fibroblasts defective in transcription coupled repair is associated with the lack of Mdm2 transactivation |
| Q24681896 | Proteasome complex as a potential cellular target of hepatitis B virus X protein |
| Q37114139 | Protein-protein interactions as targets for small-molecule therapeutics in cancer |
| Q42667933 | Prototype sequence clues within the Fanconi anaemia group C gene |
| Q33926143 | Putative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways |
| Q36412870 | RNAi for treating hepatitis B viral infection |
| Q34226294 | Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1 |
| Q33781677 | Regulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding protein |
| Q24678703 | Regulation of apoptosis by viral gene products |
| Q37350292 | Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis |
| Q35122644 | Regulatory mechanisms of viral hepatitis B and C |
| Q40598246 | Repair and transcription. Collision or collusion? |
| Q24336020 | Repression of p53-mediated transcription by MDM2: a dual mechanism |
| Q26778413 | Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma |
| Q34230585 | Role of miR-148a in hepatitis B associated hepatocellular carcinoma. |
| Q56972496 | Roles of p53 in extrinsic factor-induced liver carcinogenesis |
| Q24338301 | Rotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53 |
| Q33883607 | Rous-Whipple Award Lecture. Viruses, immunity, and cancer: lessons from hepatitis B |
| Q45279592 | Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma |
| Q38034629 | Show me your license, please: deregulation of centriole duplication mechanisms that promote amplification |
| Q44618806 | Significance of prior hepatitis B virus infection in the development of hepatocellular carcinoma in patients with chronic hepatitis C |
| Q43795086 | State of HBV DNA in HBsAg-negative, anti-HCV-positive hepatocellular carcinoma: existence of HBV DNA possibly as nonintegrated form with analysis by Alu-HBV DNA PCR and conventional HBV PCR. |
| Q28140767 | Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex |
| Q40810976 | Structural and functional involvement of p53 in BER in vitro and in vivo |
| Q35078725 | TP53 and liver carcinogenesis. |
| Q36135944 | TP53 mutation analyses on breast carcinomas: a study of paraffin-embedded archival material |
| Q36777331 | TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer |
| Q38056849 | Tackling hepatitis B virus-associated hepatocellular carcinoma--the future is now. |
| Q36134953 | The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene |
| Q77753611 | The C-terminal domain of p53 catalyzes DNA-renaturation and strand exchange toward annealing between intact ssDNAs and toward eliminating damaged ssDNA from duplex formation through preferential recognition of damaged DNA by a duocarmycin |
| Q33846651 | The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation |
| Q44449821 | The C-terminal region of the hepatitis B virus X protein is required for its stimulation of HBV replication in primary mouse hepatocytes |
| Q34246710 | The DNA damage response in viral-induced cellular transformation |
| Q34350684 | The Epstein-Barr virus immediate-early protein BZLF1 regulates p53 function through multiple mechanisms |
| Q90682184 | The Mutational Landscape of Pancreatic and Liver Cancers, as Represented by Circulating Tumor DNA |
| Q24676133 | The ORF3 protein of porcine circovirus type 2 interacts with porcine ubiquitin E3 ligase Pirh2 and facilitates p53 expression in viral infection |
| Q40021717 | The X protein of hepatitis B virus coactivates potent activation domains |
| Q45722513 | The absence of up-regulation of telomerase activity during regeneration after partial hepatectomy in hepatitis B virus X gene transgenic mice |
| Q34206346 | The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis |
| Q42467138 | The conserved amino-terminal region (amino acids 1-20) of the hepatitis B virus X protein shows a transrepression function |
| Q38331217 | The cysteine residues of the hepatitis B virus onco-protein HBx are not required for its interaction with RNA or with human p53. |
| Q38246712 | The direct and indirect roles of HBV in liver cancer: prospective markers for HCC screening and potential therapeutic targets. |
| Q24561887 | The enigmatic X gene of hepatitis B virus |
| Q40982662 | The hematopoietic transcription factor SCL binds the p44 subunit of TFIIH. |
| Q36684890 | The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors |
| Q36303449 | The hepatitis B virus X gene induces p53-mediated programmed cell death |
| Q41094269 | The hepatitis B virus X protein enhances the DNA binding potential and transcription efficacy of bZip transcription factors |
| Q45409349 | The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription. |
| Q45753547 | The hepatitis B virus X protein is a co-activator of activated transcription that modulates the transcription machinery and distal binding activators |
| Q34438821 | The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage |
| Q28355178 | The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis |
| Q38356232 | The hepatitis B virus transactivator protein, HBx, interacts with single-stranded DNA (ssDNA). Biochemical characterizations of the HBx-ssDNA interactions |
| Q36419017 | The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma. |
| Q40020868 | The murine C'-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells |
| Q96764448 | The role of MDM2-p53 axis dysfunction in the hepatocellular carcinoma transformation |
| Q28141874 | The translation initiation factor, hu-Sui1 may be a target of hepatitis B X antigen in hepatocarcinogenesis |
| Q41135209 | The tumor suppressor p53 modifies mutational processes in a human lymphoblastoid cell line |
| Q38794412 | The unique role of the hepatitis virus B X protein on HEK 293 cell morphology and cellular change |
| Q33274585 | The upregulation of expressed proteins in HepG2 cells transfected by the recombinant plasmid-containing HBx gene |
| Q40956703 | Trans-activation of cellular genes by hepatitis B virus proteins: a possible mechanism of hepatocarcinogenesis. |
| Q45752016 | Transactivation of the human MDR1 gene by hepatitis B virus X gene product |
| Q30661634 | Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue |
| Q42825156 | Transcriptional repression of p21(waf1) promoter by hepatitis B virus X protein via a p53-independent pathway |
| Q40902803 | Transcriptional repression of the human p53 gene by hepatitis B viral X protein |
| Q36269684 | Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma. |
| Q28389231 | Tumor suppressor and hepatocellular carcinoma |
| Q41625163 | Tumor suppressor genes and human cancer |
| Q34447387 | Tumor suppressor genes: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment. |
| Q34308946 | Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes |
| Q34314048 | Tumor suppressor p53 mutations and breast cancer: a critical analysis |
| Q37810431 | Tumor viruses and cancer biology: Modulating signaling pathways for therapeutic intervention |
| Q33807787 | Twenty years of p53 research: structural and functional aspects of the p53 protein |
| Q24336035 | Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression |
| Q40855904 | UVDDB p127-binding modulates activities and intracellular distribution of hepatitis B virus X protein |
| Q33669664 | Ultraviolet radiation-induced p53 responses in the epidermis are differentiation-dependent |
| Q34771678 | Upregulated expression of a unique gene by hepatitis B x antigen promotes hepatocellular growth and tumorigenesis |
| Q21245597 | Viral hepatitis and hepatocellular carcinoma |
| Q34617749 | Viral hepatocarcinogenesis |
| Q30979834 | Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data. |
| Q42205637 | X protein mutations in hepatitis B virus DNA predict postoperative survival in hepatocellular carcinoma |
| Q40121980 | X protein of hepatitis B virus functions as a transcriptional corepressor on the human telomerase promoter |
| Q34234112 | X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis |
| Q41922699 | X protein variants of the autochthonous Latin American hepatitis B virus F genotype promotes human hepatocyte death by the induction of apoptosis and autophagy |
| Q36169030 | X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo |
| Q41067693 | X-gene product of hepatitis B virus induces apoptosis in liver cells |
| Q43035178 | p21WAF1/CTP1 expression and hepatitis virus type |
| Q39785581 | p53 Promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2. |
| Q32099258 | p53 and RPA are sequestered in viral replication centers in the nuclei of cells infected with human cytomegalovirus |
| Q40370722 | p53 gene mutations and photocarcinogenesis |
| Q73089635 | p53 is a rate-limiting factor in the repair of higher-order DNA structure |
| Q24563085 | p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction |
| Q24643993 | p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner |
| Q24336880 | p53 modulation of TFIIH–associated nucleotide excision repair activity |
| Q45784277 | p53 mutations and hepatitis B virus: cofactors in hepatocellular carcinoma |
| Q33807807 | p53 regulation by post-translational modification and nuclear retention in response to diverse stresses |
| Q37049524 | p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer |
| Q41640484 | p53 tumor-suppressor gene: clues to molecular carcinogenesis |
| Q41715281 | p53--an acrobat in tumorigenesis |
| Q73567230 | p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation |
| Q41191833 | p53-dependent induction of WAF1 by heat treatment in human glioblastoma cells |
| Q34609247 | p53-mediated cellular response to DNA damage in cells with replicative hepatitis B virus |
| Q33868917 | p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding |
| Q33545318 | p53-oriented cancer therapies: current progress |
| Q42459993 | p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes |
| Q29618407 | p53: puzzle and paradigm |
| Q35196731 | pX, the HBV-encoded coactivator, suppresses the phenotypes of TBP and TAFII250 mutants |
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