scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1001770301 |
P356 | DOI | 10.1038/278261A0 |
P953 | full work available at URL | http://www.nature.com/articles/278261a0 |
http://www.nature.com/articles/278261a0.pdf | ||
P3181 | OpenCitations bibliographic resource ID | 1347156 |
P698 | PubMed publication ID | 218111 |
P50 | author | David P. Lane | Q909289 |
P2093 | author name string | L. V. Crawford | |
P2860 | cites work | Transformation of BALB/c-3T3 cells by tsA mutants of simian virus 40: temperature sensitivity of the transformed phenotype and retransofrmation by wild-type virus | Q37602234 |
An immunochemical investigation of SV40 T antigens. 1. Production properties and specificity of rabbit antibody to purified simian virus 40 large-T antigen | Q39495337 | ||
The genome of simian virus 40. | Q40142651 | ||
Antiserum to polyacrylamide gel-purified simian virus 40 T antigen | Q40155471 | ||
Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells | Q40158462 | ||
Methods for fractionation and scintillation counting of radioisotope-labeled polyacrylamide gels | Q71587915 | ||
Organization and expression of early genes of simian virus 40 | Q33954047 | ||
Spliced early mRNAs of simian virus 40 | Q33967138 | ||
Complete nucleotide sequence of SV40 DNA | Q34122821 | ||
Initiation and maintenance of cell transformation by simian virus 40: a viral genetic property | Q35070561 | ||
Expression of simian virus 40 early genes in transformed rat cells is correlated with maintenance of the transformed phenotype | Q35995573 | ||
The small subunit of HL-A antigens is beta 2-microglobulin | Q36272738 | ||
Phosphorylation of T-antigen and control T-antigen expression in cells transformed by wild-type and tsA mutants of simian virus 40 | Q36493723 | ||
Simian virus 40 functions required for the establishment and maintenance of malignant transformation | Q36532307 | ||
Regulation of tumor antigen synthesis by simain virus 40 gene A | Q36537613 | ||
Studies on nondefective adenovirus-simian virus 40 hybrid viruses. I. A newly characterized simian virus 40 antigen induced by the Ad2+ND 1 virus | Q36578182 | ||
Identification of simian virus 40 tumor and U antigens | Q37581413 | ||
Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen | Q37581427 | ||
Large and small tumor antigens from simian virus 40 have identical amino termini mapping at 0.65 map units | Q37585547 | ||
P433 | issue | 5701 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | viral antigens | Q66058032 |
neoplasm antigens | Q76832457 | ||
viral transformation | Q17162815 | ||
P304 | page(s) | 261-3 | |
P577 | publication date | 1979-03-15 | |
P1433 | published in | Nature | Q180445 |
P1476 | title | T antigen is bound to a host protein in SV40-transformed cells | |
T antigen is bound to a host protein in SY40-transformed cells | |||
P478 | volume | 278 |
Q24610856 | 100 years of Rous sarcoma virus |
Q37589207 | 30 years and a long way into p53 research |
Q55188514 | 40 Years of Research Put p53 in Translation. |
Q36966801 | 55,000-dalton, retrovirus-associated, cell membrane glycoprotein: purification and quantitative measurements of expression in viruses, cells, and tissues |
Q36906115 | 94,000- and 100,000-molecular-weight simian virus 40 T-antigens are associated with the nuclear matrix in transformed and revertant mouse cells |
Q36276108 | A 53-kilodalton protein common to chemically and virally transformed cells shows extensive sequence similarities between species |
Q41289681 | A Casein‐Kinase‐2‐Related Protein Kinase is Tightly Associated with the Large T Antigen of Simian Virus 40 |
Q36521889 | A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas |
Q99549233 | A Glance of p53 Functions in Brain Development, Neural Stem Cells, and Brain Cancer |
Q35839765 | A TEF-1-independent mechanism for activation of the simian virus 40 (SV40) late promoter by mutant SV40 large T antigens |
Q35937193 | A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18 |
Q53375840 | A comparative analysis of human papillomavirus types 16 and 18 and expression of p53 gene and Ki-67 in cervical, vaginal, and vulvar carcinomas. |
Q37249372 | A complex barcode underlies the heterogeneous response of p53 to stress |
Q68323916 | A conformation hypothesis for the suppressor and promoter functions ofp53in cell growth control and in cancer |
Q59053969 | A deadly inheritance |
Q33931645 | A deletion in the simian virus 40 large T antigen impairs lytic replication in monkey cells in vivo but enhances DNA replication in vitro: new complementation function of T antigen |
Q37697021 | A direct effect of activated human p53 on nuclear DNA replication |
Q48403147 | A fragment of the SV40 large T-antigen gene transforms |
Q36909664 | A functional simian virus 40 origin of replication is required for the generation of a super T antigen with a molecular weight of 100,000 in transformed mouse cells |
Q35842059 | A herpesvirus saimiri protein required for interleukin-2 independence is associated with membranes of transformed T cells |
Q35159385 | A mouse mutant p53 product recognized by CD4+ and CD8+ T cells |
Q37599465 | A mutant p53 protein is required for maintenance of the transformed phenotype in cells transformed with p53 plus ras cDNAs |
Q30931923 | A note from history: Landmarks in history of cancer, part 7. |
Q33909710 | A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer |
Q47161106 | A picorna-like virus suppresses the N-end rule pathway to inhibit apoptosis. |
Q36081118 | A possible screening test for inherited p53-related defects based on the apoptotic response of peripheral blood lymphocytes to DNA damage |
Q45769777 | A research shortcut from a common cold virus to human cancer |
Q34572898 | A role for p53 in the frequency and mechanism of mutation |
Q36848613 | A short-lived nuclear phosphoprotein encoded by the human ets-2 proto-oncogene is stabilized by activation of protein kinase C. |
Q34265353 | A single gene and a pseudogene for the cellular tumour antigen p53. |
Q53565320 | A small subclass of SV40 T antigen binds to the viral origin of replication |
Q77631505 | A study on p53 protein and anti-p53 antibodies in the sera of patients with oesophageal cancer |
Q45798150 | A subclass of simian virus 40 T antigen with a high cell surface binding affinity |
Q21559509 | A very late viral protein triggers the lytic release of SV40 |
Q43481603 | A wild-type p53 cytotoxic T cell epitope is presented by mouse hepatocarcinoma cells |
Q36507746 | Abelson murine leukemia virus-induced tumors elicit antibodies against a host cell protein, P50 |
Q36942353 | Abelson murine leukemia virus-transformed cells that lack p53 protein synthesis express aberrant p53 mRNA species |
Q38799291 | Aberrant hnRNP K expression: All roads lead to cancer |
Q36867443 | Ability of a T-antigen transport-defective mutant of simian virus 40 to immortalize primary cells and to complement polyomavirus middle T in tumorigenesis |
Q36792140 | Ability of p53 and the adenovirus E1b 58-kilodalton protein to form a complex is determined by p53 |
Q41462464 | Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas |
Q45796894 | Abortive transformation of rat 3Y1 cells by simian virus 40: Viral function overcoming inhibition of cellular proliferation under various conditions of culture |
Q41304024 | Accumulation of mutant p53 and hsp72 by heat treatment, and their association in a human glioblastoma cell line |
Q67509681 | Accumulation of p53 protein correlates with tumour proliferative activity in EBV positive Burkitt's lymphoma |
Q36917280 | Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts |
Q36782441 | Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life |
Q41210647 | Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form |
Q36784121 | Activation of ATPase activity of simian virus 40 large T antigen by the covalent affinity analog of ATP, fluorosulfonylbenzoyl 5'-adenosine |
Q33707445 | Activation of CREB/ATF sites by polyomavirus large T antigen |
Q33958627 | Activation of RNA polymerase III transcription in cells transformed by simian virus 40 |
Q45093761 | Activation of cellular stress protein genes by herpes simplex virus temperature-sensitive mutants which overproduce immediate early polypeptides |
Q40037740 | Activation of the human immunodeficiency virus type 1 long terminal repeat by transforming mutants of human p53. |
Q33542011 | Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system |
Q33964757 | Adenovirus E1B 55-kilodalton oncoprotein inhibits p53 acetylation by PCAF. |
Q37391112 | Adenovirus E1B 55-kilodalton protein: multiple roles in viral infection and cell transformation |
Q64381309 | Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells |
Q33606342 | Adenovirus E4orf6 oncoprotein modulates the function of the p53-related protein, p73 |
Q40676317 | Adenovirus serotype determines association and localization of the large E1B tumor antigen with cellular tumor antigen p53 in transformed cells |
Q36634353 | Adenovirus type 9 E4 open reading frame 1 encodes a transforming protein required for the production of mammary tumors in rats |
Q28756544 | Advances in chemical carcinogenesis: a historical review and prospective |
Q53472045 | Alterations in oncogene expression and radiosensitivity in the most frequently used SV40-transformed human skin fibroblasts. |
Q36827656 | Alterations in the structure of new and old forms of simian virus 40 large T antigen (T) defined by age-dependent epitope changes: new T is the same as ATPase-active T. |
Q36628203 | Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas. |
Q36698270 | Alterations of the p53 gene in nasopharyngeal carcinoma |
Q48067523 | Alterations of the p53, Rb and MDM2 genes in osteosarcoma |
Q89683056 | Alternative Mechanisms of p53 Action During the Unfolded Protein Response |
Q38179828 | Alternative splicing in cancer: implications for biology and therapy |
Q41633870 | An SV40 transformation revertant due to a host mutation: Isolation and complementation analysis |
Q45802726 | An embryo protein induced by SV40 virus transformation of mouse cells |
Q35999365 | An equation to estimate the difference between theoretically predicted and SDS PAGE-displayed molecular weights for an acidic peptide |
Q72523724 | An immunohistochemical study of p53 and proliferating cell nuclear antigen expression in progressive multifocal leukoencephalopathy |
Q40139690 | An oligomeric form of simian virus 40 large T-antigen is immunologically related to the cellular tumor antigen p53 |
Q37286062 | Analysis of genomic instability in Li-Fraumeni fibroblasts with germline p53 mutations |
Q70524574 | Analysis of mutant P53 protein in osteosarcomas and other malignant and benign lesions of bone |
Q45841148 | Analysis of simian virus 40 infection of CV-1 cells by quantitative two-color fluorescence with flow cytometry. |
Q72892744 | Analysis of the 84K, 55K, and 48K proteins immunoprecipitable by SV40 T antibody from SV40-infected and -transformed cells by tryptic peptide mapping on cation-exchange columns |
Q43447920 | Analysis of the nonviral antigens immunoprecipitable by SV40 T antibody from SV40-transformed human/mouse hybrid cell lines |
Q37113813 | Anaplastic renal carcinoma expressing SV40 T antigen in a female TRAMP mouse |
Q42003660 | Anatomy of Mdm2 and Mdm4 in evolution. |
Q40277963 | Anchorage independence: Analysis of factors affecting the growth and colony formation of wild-type and dl mutant SV40-transformed lines |
Q35458911 | Antibodies specific for the polyoma virus middle-size tumor antigen |
Q41290168 | Apoptosis and gastrointestinal pharmacology. |
Q40551607 | Apoptosis in viral infections |
Q28611432 | Apoptosis, cancer and the p53 tumour suppressor gene |
Q41741254 | Apoptosis, neurotrophic factors and neurodegeneration |
Q91923602 | Arnie Levine and the MDM2-p53 discovery: a postdoctoral fellow's perspective |
Q92125253 | Arnold J. Levine and my career development |
Q92557659 | Association Between Simian Virus 40 and Human Tumors |
Q29620421 | Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product |
Q41243025 | Association between the cellular p53 and the adenovirus 5 E1B-55kd proteins reduces the oncogenicity of Ad-transformed cells. |
Q41650259 | Association of Epstein-Barr virus infection with p53 protein accumulation but not bcl-2 protein in nasopharyngeal carcinoma |
Q36945858 | Association of Simian Virus 40 T Antigen with the Nuclear Matrix of Infected and Transformed Monkey Cells |
Q36830650 | Association of a cellular heat shock protein with simian virus 40 large T antigen in transformed cells |
Q40307090 | Association of a murine 53,000-dalton phosphoprotein with simian virus 40 large-T antigen in transformed cells |
Q36913734 | Association of adenovirus early-region 1A proteins with cellular polypeptides |
Q36685815 | Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations |
Q40307715 | Association of simian virus 40 T antigen with replicating nucleoprotein complexes of simian virus 40 |
Q38872379 | Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End. |
Q43756777 | Autoimmune expression of a cytoplasmic protein p60 in mice bearing metastasizing SV40-transformed tumors |
Q38066407 | Autophagy, apoptosis, mitoptosis and necrosis: interdependence between those pathways and effects on cancer |
Q37043057 | Autophagy: regulation and role in development |
Q59049130 | BAY 61-3606, CDKi, and Sodium Butyrate Treatments Modulate p53 Protein Level and Its Site-Specific Phosphorylation in Human Vestibular SchwannomasIn Vitro |
Q33850208 | Barrett's esophagus. Reducing the risk of progression to adenocarcinoma |
Q92503902 | Basal Level p53 Suppresses Antiviral Immunity against Foot-and-Mouth Disease Virus |
Q38282236 | Battle against cancer: an everlasting saga of p53. |
Q38129174 | Battle of the eternal rivals: restoring functional p53 and inhibiting Polo-like kinase 1 as cancer therapy |
Q73187748 | Bcl-2 accelerates multistep prostate carcinogenesis in vivo |
Q36532335 | Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter |
Q44167079 | Binding of a simian virus 40 T antigen-related protein to DNA |
Q36793131 | Binding of p53 and p105-RB is not sufficient for oncogenic transformation by a hybrid polyomavirus-simian virus 40 large T antigen |
Q40471781 | Binding studies of SV40 T-antigen to SV40 binding site II |
Q36936392 | Biochemical Activities of T-Antigen Proteins Encoded by Simian Virus 40 A Gene Deletion Mutants |
Q40067224 | Biochemical characterization of Epstein-Barr virus nuclear antigen 2A |
Q36931619 | Biochemical properties of the 145,000-dalton super-T antigen from simian virus 40-transformed BALB/c 3T3 clone 20 cells |
Q28078082 | Biofilm Forming Lactobacillus: New Challenges for the Development of Probiotics |
Q39819264 | Biological and molecular analysis of p53 cellular-encoded tumor antigen |
Q48320507 | Biology and evolution of poorly differentiated neuroendocrine tumors |
Q45797430 | Biology of simian virus 40 (SV40) transplantation antigen (TrAg) X. Tumorigenic potential of mouse cells transformed by SV40 in high responder C57BL/6 mice and correlation with the persistence of SV40 TrAg, early proteins and viral sequences |
Q44517202 | Bovine papillomavirus E1 protein affects the host cell cycle phase fractions |
Q59795032 | Breaking Bad: How Viruses Subvert the Cell Cycle |
Q35616131 | CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation |
Q47736161 | CHARACTERIZATION OF THE MUCIN PHENOTYPE CAN PREDICT GASTRIC CANCER RECURRENCE AFTER ENDOSCOPIC MUCOSAL RESECTION. |
Q26829232 | Caloric restriction: is mammalian life extension linked to p53? |
Q34568160 | Cancer genetics: from Boveri and Mendel to microarrays |
Q36921031 | Candidate product of the FBJ murine osteosarcoma virus oncogene: characterization of a 55,000-dalton phosphoprotein |
Q41072546 | Capacity of UV-irradiated human fibroblasts to support adenovirus DNA synthesis correlates with transcription-coupled repair and is reduced in SV40-transformed cells and cells expressing mutant p53. |
Q41198562 | Casein kinase 2 inhibits the renaturation of complementary DNA strands mediated by p53 protein. |
Q69612136 | Cell cycle dependent genes inducible by different mitogens in cells from different species |
Q38218288 | Cell cycle regulation during viral infection |
Q40442266 | Cell cycle regulation in response to DNA damage in mammalian cells: A historical perspective |
Q41514084 | Cell specificity of transcription regulation by papovavirus T antigens and DNA replication |
Q37177493 | Cellular adaptation to hypoxia and p53 transcription regulation |
Q37417605 | Cellular and sub-cellular responses to UVA in relation to carcinogenesis |
Q35981213 | Cellular factors required for multiple stages of SV40 DNA replication in vitro |
Q43927270 | Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53 |
Q36503362 | Cellular proteins associated with simian virus 40 early gene products in newly infected cells |
Q40145588 | Cellular proteins reactive with monoclonal antibodies directed against simian virus 40 T-antigen |
Q36561672 | Cellular transformation and malignancy induced by ras require c-jun |
Q34985587 | Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens |
Q90642065 | Ceramide Signaling and p53 Pathways |
Q41454671 | Characterization by human autoantibody of a nuclear antigen related to the cell cycle |
Q33403060 | Characterization of SV-40 Tag rats as a model to study prostate cancer |
Q41341089 | Characterization of a murine p53SER246 mutant equivalent to the human p53SER249 associated with hepatocellular carcinoma and aflatoxin exposure |
Q45801837 | Characterization of a temperature-sensitive, DNA-positive, nontransforming mutant of simian virus 40 |
Q36906979 | Characterization of am404, an amber mutation in the simian virus 40 T antigen gene |
Q40266110 | Characterization of different tumor antigens present in cells transformed by simian virus 40 |
Q53556960 | Characterization of human p53 antigens employing primate specific monoclonal antibodies |
Q40660065 | Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells |
Q38507377 | Characterization of rat spiral ligament cell line immortalized by adenovirus 12-simian virus 40 hybrid virus |
Q36876699 | Characterization of simian virus 40 large T antigen by using different monoclonal antibodies: T-p53 complexes are preferentially ATPase active and adenylylated |
Q36507665 | Characterization of tau antigens isolated from uninfected and simian virus 40-infected monkey cells and papovavirus-transformed cells |
Q40669877 | Characterization of the human p53 gene |
Q36955441 | Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells |
Q38960399 | Characterization, expression and silencing by RNAi of p53 from Penaeus monodon |
Q40674478 | Chromosomal Assignment of the Murine Gene Encoding the Transformation-Related Protein p53 |
Q40931241 | Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance |
Q37973676 | Chromosome instability and deregulated proliferation: an unavoidable duo. |
Q28201920 | Clinical and Pathologic Relevance of p53 Index in Canine Osseous Tumors |
Q77711290 | Clinical implications of molecular abnormalities in lung cancer |
Q48011034 | Clinical significance of detecting p53 protein in Burkitt lymphoma and B-cell acute lymphoblastic leukemia using immunocytochemistry |
Q27002356 | Clinical utility of anti-p53 auto-antibody: systematic review and focus on colorectal cancer |
Q40461080 | Cloning and expression analysis of full length mouse cDNA sequences encoding the transformation associated protein p53. |
Q36660357 | Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. |
Q26752209 | CncRNAs: RNAs with both coding and non-coding roles in development |
Q72352371 | Coexpression of HER-2/neu and p53 is associated with a shorter disease-free survival in node-positive breast cancer patients |
Q33826650 | Common threads in persistent viral infections |
Q36301535 | Comparative analysis of p73 and p53 regulation and effector functions |
Q42281113 | Comparison of p53 gene mutation and protein overexpression in colorectal carcinomas |
Q38632111 | Comparisons between murine polyomavirus and Simian virus 40 show significant differences in small T antigen function |
Q36798180 | Complex formation between the lymphotropic papovavirus large tumor antigen and the tumor suppressor protein p53. |
Q40064063 | Complex formation of human T-cell leukemia virus type I p40tax transactivator with cellular polypeptides. |
Q33589833 | Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product |
Q40308362 | Complex formation of simian virus 40 large T antigen with cellular protein p53. |
Q35299950 | Complex of simian virus 40 large tumor antigen and 48,000-dalton host tumor antigen |
Q35235746 | Complex of simian virus 40 large-T antigen and host 53,000-molecular-weight protein in monkey cells |
Q38313400 | Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants. |
Q36574046 | Constitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression |
Q36832520 | Constitutive expression of simian virus 40 large T antigen in monkey cells activates their capacity to support polyomavirus replication |
Q36923165 | Construction and Characterization of Viable Deletion Mutants of Simian Virus 40 Lacking Sequences near the 3′ End of the Early Region |
Q24633347 | Contagious cancer |
Q58546230 | Contribution of DNA replication to the FAM111A-mediated simian virus 40 host range phenotype |
Q47671672 | Control mechanisms in germ cells mediated by p53 family proteins. |
Q36397275 | Control of cell migration: a tumour suppressor function for p53? |
Q28236097 | Control of the G2/M transition |
Q38113943 | Control the host cell cycle: viral regulation of the anaphase-promoting complex |
Q36945247 | Conversion Through Homologous Recombination of the Gene Encoding Simian Virus 40 115,000-Molecular-Weight Super T Antigen to a Gene Encoding a Normal-Size Large T Antigen Variant |
Q53548575 | Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. |
Q47791886 | Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein |
Q41636011 | Cooperation of p53 and polyoma virus middle T antigen in the transformation of primary rat embryo fibroblasts |
Q38290890 | Cooperation of simian virus 40 large and small T antigens in metabolic stabilization of tumor suppressor p53 during cellular transformation |
Q57268282 | Coordinate expression of the 48K host nuclear phosphoprotein and SV40 T Ag upon primary infection of mouse cells |
Q44557313 | Correlated abnormalities of transforming growth factor-β1 response and p53 expression in thyroid epithelial cell transformation |
Q44517585 | Correlation of p53 protein expression in human urothelial transitional cell cancers with malignant potential and patient survival |
Q37254784 | Correlation of transcription of MALAT-1, a novel noncoding RNA, with deregulated expression of tumor suppressor p53 in small DNA tumor virus models |
Q24301537 | Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor |
Q36510188 | Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation |
Q40491794 | Current Topics of Immunohistochemistry as Applied to Skin Tumors |
Q45947167 | Cytokine-induced modulation of tumor suppressor gene expression in ovarian cancer cells: up-regulation of p53 gene expression and induction of apoptosis by tumor necrosis factor-alpha. |
Q43140225 | Cytoplasmic sequestration of p53 promotes survival in leukocytes transformed by Theileria |
Q38316929 | DNA Structure and Polymerase Fidelity: A New Role for A-DNA. |
Q91983815 | DNA Tumor Viruses and Their Contributions to Molecular Biology |
Q30842780 | DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression. |
Q58052330 | Data Integration: Towards Understanding Biological Complexity |
Q71560974 | Decreasing p53 overexpression in sequential, recurrent, oral squamous cell carcinomas |
Q38332737 | Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation |
Q36835468 | Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation |
Q61449903 | Deregulation and Targeting of TP53 Pathway in Multiple Myeloma |
Q35941628 | Deregulation of the cell cycle by the Epstein-Barr virus |
Q35235163 | Detection and characterization of multiple forms of simian virus 40 large T antigen |
Q72908880 | Detection and characterization of viral genomes and search for tumoral antigens in two hamster cell lines derived from tumors induced by bovine papillomavirus type 1 |
Q45613582 | Detection and expression of human BK virus sequences in neoplastic prostate tissues |
Q72608634 | Detection of P53 tumor-suppressor-gene protein in bladder tumors and prostate cancer: possible clinical implications |
Q35298187 | Detection of a common feature in several human tumor cell lines--a 53,000-dalton protein |
Q57211763 | Detection of a novel, primate-specific 'kill switch' tumor suppression mechanism that may fundamentally control cancer risk in humans: an unexpected twist in the basic biology of TP53 |
Q46456704 | Detection of p53 gene mutations in oral squamous cell carcinomas of a black African population sample |
Q42487822 | Detection of p53 protein and Ki-67 proliferation antigen in human papillomavirus (HPV)-positive and HPV-negative cervical lesions by immunohistochemical double-staining |
Q37949279 | Development of new cell lines for animal cell biotechnology |
Q41062527 | Dexamethasone-induced radioresistance occurring independent of human papilloma virus gene expression in cervical carcinoma cells |
Q36536905 | Diagnostic utility of oncogenes and their products in human cancer |
Q33997846 | Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress |
Q36940094 | Different forms of simian virus 40 large tumor antigen varying in their affinities for DNA |
Q41155486 | Differential Taxol-dependent arrest of transformed and nontransformed cells in the G1 phase of the cell cycle, and specific-related mortality of transformed cells |
Q36888762 | Differential ability of a T-antigen transport-defective mutant of simian virus 40 to transform primary and established rodent cells. |
Q35871078 | Differential interaction of temperature-sensitive simian virus 40 T antigens with tumor suppressors pRb and p53 |
Q40829313 | Differential phosphorylation of mitogen-activated protein kinase families by epidermal growth factor and ultraviolet B irradiation in SV40-transformed human keratinocytes |
Q28572538 | Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence |
Q40131883 | Dimers and complexes with p53 are the prevalent oligomeric forms of a transforming nonkaryophilic T antigen of simian virus 40. |
Q36841865 | Discontinuous native protein gel electrophoresis: pros and cons |
Q33738750 | Discovery of Mieap-regulated mitochondrial quality control as a new function of tumor suppressor p53 |
Q34060590 | Discovery of a p53 variant that controls metastasis |
Q36921966 | Discrete regions of simian virus 40 large T antigen are required for nonspecific and viral origin-specific DNA binding |
Q64956138 | Discussion of some 'knowns' and some 'unknowns' about the tumour suppressor p53. |
Q34537149 | Disruption of oncogene/tumor suppressor networks during human carcinogenesis |
Q40554501 | Distinct functions for WRN and TP53 in a shared pathway of cellular response to 1-beta-D-arabinofuranosylcytosine and bleomycin. |
Q39744147 | Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma--associated Herpesvirus Lymphomas |
Q42072409 | Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2. |
Q73960260 | Does p53 immunostaining improve diagnostic accuracy in urine cytology? |
Q37229811 | Double immunostaining for p53 and molecular chaperone hsp72/73 in gastric carcinoma |
Q42945496 | Down-regulation of p53 by double-stranded RNA modulates the antiviral response |
Q35101871 | Drug discovery and p53. |
Q36387594 | Dual Roles of MDM2 in the Regulation of p53: Ubiquitination Dependent and Ubiquitination Independent Mechanisms of MDM2 Repression of p53 Activity |
Q36910554 | Dynamic nature of the association of large tumor antigen and p53 cellular protein with the surfaces of simian virus 40-transformed cells |
Q35206764 | E1A signaling to p53 involves the p19(ARF) tumor suppressor |
Q40896659 | E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage |
Q36358319 | EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins. |
Q33915487 | Effect of a tsA mutation of simian virus 40 late gene expression: variations between host cell lines |
Q45807849 | Effect of simian virus 40 infection on albumin production by hepatocytes cultured in chemically defined medium and plated on collagen and non-collagen attachment surfaces |
Q38348780 | Effects of 2-amino-4,6-dinitrotoluene on p53 tumor suppressor gene expression |
Q29619196 | Effects of an Rb mutation in the mouse |
Q35993764 | Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck. |
Q42510424 | Elevated levels of the p53 tumour suppressor protein in the basal layer of recurrent laryngeal papillomas |
Q28077156 | Emerging Non-Canonical Functions and Regulation by p53: p53 and Stemness |
Q35551117 | Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability. |
Q64374614 | Encounters with adenovirus |
Q36941962 | Energy Requirement for Degradation of Tumor-Associated Protein p53 |
Q34050026 | Enhanced degradation of p53 protein in HPV-6 and BPV-1 E6-immortalized human mammary epithelial cells. |
Q92860212 | Enzymatic Degradation of Biofilm by Metalloprotease From Microbacterium sp. SKS10 |
Q33839135 | Epidemiology and molecular genetics of colorectal cancer |
Q40136771 | Epstein-Barr virus (EBV), lymphocytes and transformation |
Q38356037 | Epstein-Barr virus nuclear antigen 2 and latent membrane protein independently transactivate p53 through induction of NF-kappaB activity |
Q34326542 | Epstein-Barr virus/complement fragment C3d receptor (CR2) reacts with p53, a cellular antioncogene-encoded membrane phosphoprotein: detection by polyclonal anti-idiotypic anti-CR2 antibodies |
Q55395428 | Evaluation of an indicator for lymph node metastasis of esophageal squamous cell carcinoma invading the submucosal layer. |
Q36845840 | Evidence for a structural relationship between BRCT domains and the helicase domains of the replication initiators encoded by the Polyomaviridae and Papillomaviridae families of DNA tumor viruses. |
Q42930582 | Evidence for modulation of BAG3 by polyomavirus JC early protein. |
Q36830520 | Evolutionary conservation of the biochemical properties of p53: specific interaction of Xenopus laevis p53 with simian virus 40 large T antigen and mammalian heat shock proteins 70 |
Q36724486 | Excess wild-type p53 blocks initiation and maintenance of simian virus 40 transformation |
Q36547790 | Exploiting the p53 pathway for the diagnosis and therapy of human cancer. |
Q37083966 | Expression and interactions of human adenovirus oncoproteins |
Q36859189 | Expression of 100,000-Mr simian virus 40 (SV40) tumor antigen in mouse fibroblasts transfected with replication-defective SV40 genomes |
Q73719734 | Expression of PCNA and p53 in esophageal dysplasia and esophageal carcinoma |
Q45801095 | Expression of SV40 T antigen polypeptides in cells biochemically transformed by plasmids containing the herpes simplex virus thymidine kinase gene and the genome of an SV40tsA mutant |
Q40675623 | Expression of Simian Virus 40 Large T Antigen in Embryonal Carcinoma Cell Hybrids |
Q28287375 | Expression of a candidate ataxia-telangiectasia group D gene in cultured fibroblast cell lines and human tissues |
Q36932745 | Expression of a transformation-related protein (p53) in the malignant stage of Friend virus-induced diseases |
Q34378463 | Expression of mutant p53 protein in hepatocellular carcinoma |
Q35984818 | Expression of mutant p53, c-erbB-2 and the epidermal growth factor receptor in transitional cell carcinoma of the human urinary bladder |
Q35903258 | Expression of p24, a novel p21Waf1/Cip1/Sdi1-related protein, correlates with measurement of the finite proliferative potential of rodent embryo fibroblasts |
Q35522870 | Expression of p53 mutant nuclear phosphoprotein in oral carcinoma and potentially malignant oral lesions |
Q72089540 | Expression of p53 product in Chinese human bladder carcinoma |
Q36235611 | Expression of simian virus 40 large T (tumor) oncogene in mouse chondrocytes induces cell proliferation without loss of the differentiated phenotype |
Q37428803 | Extensive post-translational modification of active and inactivated forms of endogenous p53. |
Q38363488 | F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4. |
Q40466587 | Familial breast cancer and genes involved in breast carcinogenesis |
Q30669552 | Feedback regulation between orphan nuclear receptor TR2 and human papilloma virus type 16. |
Q73102796 | Flow cytometry and quantitative immunohistochemical study of cell cycle regulation proteins in invasive breast carcinoma: prognostic significance |
Q36309667 | Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells |
Q36863092 | Free and viral chromosome-bound simian virus 40 T antigen: changes in reactivity of specific antigenic determinants during lytic infection |
Q36729673 | Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines |
Q38705286 | Friend virus-induced erythroleukemia: a multistage malignancy |
Q36686649 | From growth arrest to growth suppression |
Q34164614 | From p63 to p53 across p73. |
Q64102183 | Functional Diversity of p53 in Human and Wild Animals |
Q36648185 | Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency |
Q36637002 | Functional characterization of Xenopus laevis p53: evidence of temperature-sensitive transactivation but not of repression |
Q36685139 | Functional characterization of temperature-sensitive mutants of simian virus 40 large T antigen |
Q43772756 | Functional consequences of oncogene-induced photoreceptor degeneration in transgenic mice |
Q36698048 | Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression |
Q38300638 | Functional inactivation but not structural mutation of p53 causes liver cancer. |
Q40107890 | Functional interaction of nuclear transport-defective simian virus 40 large T antigen with chromatin and nuclear matrix |
Q36873869 | Functional role of BK virus tumor antigens in transformation |
Q40101353 | Functions of T antigens of SV40 and polyomavirus |
Q35976056 | Gastric cancer with p53 overexpression has high potential for metastasising to lymph nodes |
Q72661833 | Gene analysis of K-, H-ras, p53, and retinoblastoma susceptibility genes in human lung cancer cell lines by the polymerase chain reaction/single-strand conformation polymorphism method |
Q41844172 | Gene mutations and increased levels of p53 protein in human squamous cell carcinomas and their cell lines |
Q40849028 | Gene therapy for colon cancer. |
Q33755140 | Gene therapy using SV40-derived vectors: what does the future hold? |
Q41051771 | Generation and characterization of an immortal cell line of xeroderma pigmentosum group E. |
Q36845425 | Generation of murine stromal cell lines supporting hematopoietic stem cell proliferation by use of recombinant retrovirus vectors encoding simian virus 40 large T antigen |
Q54966492 | Genetic Alteration of p53 in Some Patients with Adult T-Cell Leukemia |
Q34813092 | Genetic alterations in ovarian cancer cells that might account for sensitivity to chemotherapy in patients. |
Q35861223 | Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members. |
Q36903846 | Genetic and biochemical analysis of transformation-competent, replication-defective simian virus 40 large T antigen mutants |
Q34438119 | Genetic predisposition to cancer and familial cancer syndromes |
Q38068825 | Genome guardian p53 and viral infections |
Q36642204 | Genomic alterations associated with loss of heterozygosity for TP53 in Li-Fraumeni syndrome fibroblasts |
Q36493335 | Genotype phenotype correlation in Li-Fraumeni syndrome kindreds and its implications for management. |
Q34057911 | Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes. |
Q41816411 | Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome |
Q33534212 | Gliomas |
Q35230883 | Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. |
Q42819146 | Growth regulation of a cellular tumour antigen, p53, in nontransformed cells |
Q37421517 | Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression |
Q40720204 | HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis |
Q36872778 | HSP70 binding sites in the tumor suppressor protein p53. |
Q40794530 | Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis |
Q35101216 | Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3 |
Q28569202 | Hepatitis C virus NS5A protein binds TBP and p53, inhibiting their DNA binding and p53 interactions with TBP and ERCC3 |
Q38309880 | Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability |
Q50856462 | Hepatocellular proliferation and development of hepatocellular carcinoma: a case-control study in chronic hepatitis C. |
Q56928447 | Hereditary breast cancer |
Q40970549 | Hereditary cancer: two hits revisited |
Q41562003 | Herpes simplex virus infection causes the accumulation of a heat-shock protein |
Q40755915 | Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants |
Q34091002 | Heterochromatin silencing of p53 target genes by a small viral protein |
Q37605827 | Heterogeneity of Li-Fraumeni syndrome links to unequal gain-of-function effects of p53 mutations. |
Q53418672 | Heterotopic endochondrial ossification with mixed tumor formation in C3(1)/Tag transgenic mice is associated with elevated TGF-beta1 and BMP-2 expression. |
Q55037712 | High frequency of p53 abnormality in laryngeal cancers of heavy smokers and its relation to human papillomavirus infection. |
Q36760672 | High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene |
Q35833598 | High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma |
Q35823973 | High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas |
Q39875158 | High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation. |
Q38019869 | History of protein-protein interactions: from egg-white to complex networks |
Q70197165 | Hormone-dependent enhancement of neoplastic phenotype expression by MuMTV-infected heterologous cells, and MuMTV-induced cellular antigens |
Q36350356 | Host nuclear proteins expressed in simian virus 40-transformed and -infected cells |
Q36667622 | Hot-spot p53 mutants interact specifically with two cellular proteins during progression of the cell cycle |
Q91701456 | How TP53 (almost) became an oncogene |
Q38170081 | How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis |
Q38367375 | How do viruses control mitochondria-mediated apoptosis? |
Q74266124 | How is the mutational status for tumor suppressors p53 and p16(INK4A) in MFH of the bone? |
Q91533177 | How mutant p53 empowers Foxh1 fostering leukaemogenesis? |
Q36102815 | Human BK Polyomavirus-The Potential for Head and Neck Malignancy and Disease |
Q24609227 | Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator |
Q24562978 | Human TAFII31 protein is a transcriptional coactivator of the p53 protein |
Q35873729 | Human cytomegalovirus mtrII oncoprotein binds to p53 and down-regulates p53-activated transcription |
Q40046680 | Human oncogenic viruses: nature and discovery |
Q58131437 | Human p53 and Hdm2: Cloning and Construction of Expression Plasmid |
Q40678382 | Human p53 inhibits growth in Schizosaccharomyces pombe |
Q33643799 | Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2 |
Q41098425 | Human papillomavirus (HPV) 16 E6 sensitizes cells to atractyloside-induced apoptosis: role of p53, ICE-like proteases and the mitochondrial permeability transition |
Q28187745 | Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcription |
Q36893766 | Human polyomavirus JC virus genome |
Q45137833 | Human thymic epithelial cells are frequently transformed by retroviral vectors encoding simian virus 40 |
Q36507591 | Identification and initial characterization of a new low-molecular-weight virus-encoded T antigen in a line of simian virus 40-transformed cells |
Q36930790 | Identification of B-lymphotropic papovavirus-coded proteins. |
Q37068526 | Identification of an overprinting gene in Merkel cell polyomavirus provides evolutionary insight into the birth of viral genes |
Q24337360 | Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus |
Q29620442 | Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product |
Q37212448 | Identification of new p53 acetylation sites in COS-1 cells |
Q36867104 | Identification of the p53 protein domain involved in formation of the simian virus 40 large T-antigen-p53 protein complex |
Q37731374 | Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response |
Q30987442 | Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression |
Q38045922 | Imidazoline derivatives: a patent review (2006--present). |
Q34019492 | Immortalization of a primate bipotent epithelial liver stem cell |
Q26829548 | Immortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neurons |
Q53482889 | Immunization of mice with baculovirus-derived recombinant SV40 large tumour antigen induces protective tumour immunity to a lethal challenge with SV40-transformed cells |
Q73223966 | Immunohistochemical Detection of p53 and c-erbB-2 Proteins: Prognostic Significance in Operable Breast Cancer |
Q70641343 | Immunohistochemical detection of the p53 oncoprotein in tumours of melanocytic origin |
Q71797512 | Immunohistochemical expression of p53 protein and proliferating cell nuclear antigen in hepatocellular carcinoma |
Q35832962 | Immunohistochemical study of p53 in human lung carcinomas. |
Q43444816 | Immunophenotype of SV40-T gene transfected epithelial cell lines derived from human benign breast tumors |
Q36918852 | Immunoprecipitation of some forms of simian virus 40 large-T antigen by antibodies to synthetic peptides |
Q62631293 | Impact of p53 arg72pro SNP on Breast Cancer Risk in North Indian Population |
Q35111076 | Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53. |
Q35123468 | Improving cancer therapy by non-genotoxic activation of p53. |
Q33767424 | In situ detection of apoptosis at sites of chronic bacterially induced inflammation in human gingiva |
Q55240856 | In situ polymerase chain reaction detection of HTLV-I provirus and expression of the p53 tumor suppressor gene in infiltrating cells in skeletal muscle from a patient with adult T cell leukemia. |
Q40666508 | In vitro expression of human p53 cDNA clones and characterization of the cloned human p53 gene |
Q72399727 | In vitro mutagenesis of a putative DNA binding domain of SV40 large-T |
Q39873297 | In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes |
Q33629594 | In vivo recombinant adenovirus-mediated p53 gene therapy in a syngeneic rat model for colorectal cancer |
Q40675444 | Inactivation of p53 Gene Expression by an Insertion of Moloney Murine Leukemia Virus-Like DNA Sequences |
Q39870530 | Inactivation of the retinoblastoma susceptibility protein is not sufficient for the transforming function of the conserved region 2-like domain of simian virus 40 large T antigen. |
Q35237286 | Increased concentration of an apparently identical cellular protein in cells transformed by either Abelson murine leukemia virus or other transforming agents |
Q35609543 | Increased expression of p53 protein in human leukemia cells |
Q37013182 | Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. |
Q36891202 | Induction of cellular DNA synthesis by a simian virus 40 mutant defective in nuclear transport of T antigen |
Q34127232 | Induction of interferon-stimulated genes by Simian virus 40 T antigens |
Q41371638 | Induction of interleukin-2 transcription by the hamster polyomavirus middle T antigen: a role for Fyn in T cell signal transduction |
Q33656171 | Induction of p53, p21 and apoptosis by silencing the NF90/NF45 complex in human papilloma virus-transformed cervical carcinoma cells |
Q42281248 | Infrequent involvement of p53 gene mutations in the tumourigenesis of Japanese prostate cancer |
Q24317013 | Inhibition of p53 DNA binding by human papillomavirus E6 proteins |
Q39606488 | Inhibition of p53 tumor suppressor by viral interferon regulatory factor |
Q40038319 | Inhibition of p53-mediated transactivation by E6 of type 1, but not type 5, 8, or 47, human papillomavirus of cutaneous origin. |
Q40066650 | Inhibition of viral and cellular promoters by human wild-type p53 |
Q37855826 | Inhibitors of MDM2 and MDMX: a structural perspective. |
Q41500820 | Initiation of autoimmunity to self-proteins complexed with viral antigens |
Q36362919 | Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen |
Q43131463 | Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins |
Q41461437 | Integration of Ecogpt and SV40 early region sequences into human chromosome 17: a dominant selection system in whole cell and microcell human-mouse hybrids |
Q36935658 | Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex |
Q24547088 | Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen |
Q36579279 | Interaction of retinoblastoma protein family members with large T-antigen of primate polyomaviruses |
Q33292223 | Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteins |
Q22008057 | Interaction of the single-stranded DNA-binding protein Puralpha with the human polyomavirus JC virus early protein T-antigen |
Q28776004 | Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway |
Q36920345 | Interactions between polyomavirus medium T antigen and three cellular proteins of 88, 61, and 37 kilodaltons |
Q45806859 | Intercellular communication and the control of growth: XII. Alteration of junctional permeability by simian virus 40. Roles of the large and small T antigens |
Q42818894 | Intermolecular phosphorylation between insulin holoreceptors does not stimulate substrate kinase activity |
Q36604805 | Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors |
Q36384554 | Intestinal mucositis: the role of the Bcl-2 family, p53 and caspases in chemotherapy-induced damage. |
Q40134237 | Intracellular location and kinetics of complex formation between simian virus 40 T antigen and cellular protein p53 |
Q34812489 | Introduction of wild-type p53 in a human ovarian cancer cell line not expressing endogenous p53 |
Q35103185 | Introduction: The Changing Directions of p53 Research |
Q37352771 | Investigations on a clinically and functionally unusual and novel germline p53 mutation |
Q36318172 | Involvement of PP2A in viral and cellular transformation |
Q41592444 | Involvement of p53 in cell differentiation and development |
Q36167487 | Involvement of the Epstein-Barr virus in the nasopharyngeal carcinoma pathogenesis. |
Q24555633 | Isolation and characterization of a human p53 cDNA clone: expression of the human p53 gene |
Q24318228 | Isolation and identification of the human homolog of a new p53-binding protein, Mdmx |
Q44645744 | Isolation and partial characterization of a 55,000-dalton protein induced in cells transformed by the ml strain of moloney murine sarcoma virus |
Q40665592 | Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule |
Q39585155 | J domain-independent regulation of the Rb family by polyomavirus large T antigen |
Q42828333 | JC virus large T protein transforms rodent cells but is not involved in human medulloblastoma |
Q40849418 | Karyotypic and molecular abnormalities in chronic lymphocytic leukaemia |
Q41188296 | Laboratory probing of oncogenes from human liquid and solid specimens as markers of exposure to toxicants |
Q41249912 | Lack of p53 mutations and loss of heterozygosity in non-cultured human melanocytic lesions |
Q40820817 | Lack of ultraviolet-light inducibility of the medakafish (Oryzias latipes) tumor suppressor gene p53. |
Q36867876 | Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts |
Q34432117 | Li-Fraumeni syndrome – a molecular and clinical review |
Q34618683 | Likelihood Models of Somatic Mutation and Codon Substitution in Cancer Genes |
Q36831658 | Linker insertion mutants of simian virus 40 large T antigen that show trans-dominant interference with wild-type large T antigen map to multiple sites within the T-antigen gene |
Q33870289 | Liver-directed gene therapy: promises, problems and prospects at the turn of the century |
Q59057697 | Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells |
Q36938740 | Localization of the Adenovirus E1Aa Protein, a Positive-Acting Transcriptional Factor, in Infected Cells Infected Cells |
Q36695353 | Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins |
Q36685600 | Long-term gene expression in dividing and nondividing cells using SV40-derived vectors. |
Q80586970 | Loss of c-abl facilitates anchorage-independent growth of p53- and RB- deficient primary mouse embryonic fibroblasts |
Q39455963 | Loss of p19(ARF) eliminates the requirement for the pRB-binding motif in simian virus 40 large T antigen-mediated transformation |
Q36828231 | Loss of p53 protein in human papillomavirus type 16 E6-immortalized human mammary epithelial cells |
Q40794489 | Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity |
Q53385488 | Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice. |
Q36897933 | MC29 virus-coded protein occurs as monomers and dimers in transformed cells |
Q41633106 | MDM2--arbiter of p53's destruction |
Q52340395 | MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options? |
Q24561971 | MDMX: a novel p53-binding protein with some functional properties of MDM2 |
Q37676784 | Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells |
Q35977776 | Malignant progression of SV40-immortalised human milk epithelial cells |
Q35589990 | Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from simian virus 40-transformed 3T3 cells |
Q28609886 | Mapping of the p53 and mdm-2 Interaction Domains |
Q35235117 | Mapping of the viral mRNA encoding a super-T antigen of 115,000 daltons expressed in simian virus 40-transformed rat cell lines |
Q27025941 | Matrix and backstage: cellular substrates for viral vaccines |
Q36386557 | Mechanism of interferon action: Simian virus 40-specific early polypeptides synthesized in untreated and interferon-treated monkey kidney cells |
Q73320007 | Mechanism of p53 degradation |
Q36273391 | Mechanisms and markers of carcinogenesis and neoplastic progression |
Q40667913 | Mechanisms of action of the p53 tumor suppressor and prospects for cancer gene therapy by reconstitution of p53 function |
Q36698827 | Mechanisms of interference with simian virus 40 (SV40) DNA replication by trans-dominant mutants of SV40 large T antigen |
Q33722859 | Mechanisms of p53 loss in human sarcomas |
Q36884544 | Medium tumor antigen of polyomavirus transformation-defective mutant NG59 is associated with 73-kilodalton heat shock protein |
Q37067101 | Merkel cell carcinoma: a virus-induced human cancer |
Q34947967 | Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus |
Q36468289 | Merkel cell polyomavirus: a newly discovered human virus with oncogenic potential |
Q34309882 | Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus |
Q64078232 | Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells |
Q43665417 | Metastasizing neuroblastomas from taste buds in rats transgenic for the Simian virus 40 large T antigen under control of the probasin gene promoter |
Q29547697 | Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours |
Q26785743 | Microbial Regulation of p53 Tumor Suppressor |
Q36316665 | Microinjection of monoclonal antibody to protein p53 inhibits serum-induced DNA synthesis in 3T3 cells |
Q37576004 | Micrometastasis expressing insulin arise in lung and spleen at advanced stage of rip1-tag2 transgenic mice |
Q90421599 | Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila |
Q40399548 | Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K. |
Q58695374 | Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers |
Q29615657 | Modes of p53 regulation |
Q37512255 | Modulation of autophagy-like processes by tumor viruses |
Q40062749 | Modulation of immortalizing properties of human papillomavirus type 16 E7 by p53 expression. |
Q36925553 | Modulation of p53 protein expression during cellular transformation with simian virus 40 |
Q35367195 | Molecular biology in the diagnosis and prognosis of solid and lymphoid tumors |
Q41131665 | Molecular biology of pediatric gliomas |
Q39726667 | Molecular biology of the cell cycle |
Q36489098 | Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53. |
Q41353388 | Molecular genetics of colorectal cancer (part 1). |
Q30495393 | Molecular genetics of neurological tumours |
Q36827597 | Molecular mechanisms in lung pathogenesis |
Q30498610 | Molecular mechanisms of cancer |
Q33368199 | Molecular pathogenesis of colorectal cancer |
Q29616471 | Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers |
Q33920832 | Monoclonal antibodies against simian virus 40 T antigens: evidence for distinct sublcasses of large T antigen and for similarities among nonviral T antigens |
Q35235589 | Monoclonal antibodies against simian virus 40 tumor antigens: analysis of antigenic binding sites, using adenovirus type 2-simian virus 40 hybrid viruses |
Q33933776 | Monoclonal antibodies displaying a novel species specificity for the primate transformation-related protein, p53. |
Q34249232 | Monoclonal antibodies specific for simian virus 40 tumor antigens |
Q36347553 | Monoclonal antibody against human T cell leukemia virus p19 defines a human thymic epithelial antigen acquired during ontogeny |
Q40127251 | Monoclonal antibody analysis of p53 expression in normal and transformed cells |
Q40116257 | Monoclonal antibody analysis of simian virus 40 small t-antigen expression in infected and transformed cells |
Q26746524 | Mouse Models in Prostate Cancer Translational Research: From Xenograft to PDX |
Q38351451 | Mouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium |
Q36436702 | Mouse bites dogma: how mouse models are changing our views of how P53 is regulated in vivo |
Q38447567 | Mouse lung neuroendocrine carcinomas: distinct morphologies, same transcription factors. |
Q58693513 | Mouse models of prostate cancer |
Q46905586 | Mouse p53 inhibits SV40 origin-dependent DNA replication |
Q44673371 | Mouse polyomavirus large T antigen inhibits cell growth and alters cell and colony morphology in Saccharomyces cerevisiae. |
Q42526715 | Multiple mechanisms contribute to the activation of RNA polymerase III transcription in cells transformed by papovaviruses |
Q48026339 | Multisite phosphorylation and the integration of stress signals at p53. |
Q36736774 | Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication |
Q40410709 | Murine models of neoplasia: functional analysis of the tumour suppressor genes Rb-1 and p53. |
Q41519041 | Musculoskeletal oncology--advances in cytogenetics and molecular genetics and their clinical implications |
Q30354662 | Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers. |
Q36920336 | Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1 |
Q36698822 | Mutant p53 can substitute for human papillomavirus type 16 E6 in immortalization of human keratinocytes but does not have E6-associated trans-activation or transforming activity |
Q35081210 | Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells |
Q38204111 | Mutant p53 exerts oncogenic effects through microRNAs and their target gene networks |
Q36661775 | Mutant p53 proteins: between loss and gain of function |
Q36777355 | Mutant p53: an oncogenic transcription factor |
Q36070574 | Mutant p53: one name, many proteins |
Q40951665 | Mutation and cancer: a personal odyssey |
Q36780709 | Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation |
Q40535104 | Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53. |
Q36803951 | Mutation of the serine 312 phosphorylation site does not alter the ability of mouse p53 to inhibit simian virus 40 DNA replication in vivo |
Q36936356 | Mutational Analysis of Simian Virus 40 T Antigen: Isolation and Characterization of Mutants with Deletions in the T-Antigen Gene |
Q33940332 | Mutational analysis of simian virus 40 large T antigen DNA binding sites |
Q47691368 | Mutations in context: implications of BRCA testing in diverse populations |
Q35982987 | Mutations in p53 do not account for heritable breast cancer: a study in five affected families |
Q37599484 | Mutations in the bovine leukemia virus Tax protein can abrogate the long terminal repeat-directed transactivating activity without concomitant loss of transforming potential |
Q74597212 | Mutations in the p53 gene in acute myeloid leukemia patients correlate with poor prognosis |
Q28249770 | Mutations in the p53 gene occur in diverse human tumour types |
Q40771480 | Mutations of the p53 gene in B-cell lymphoma |
Q40924895 | Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis. |
Q40062939 | Mutual functional antagonism of the simian virus 40 T antigen and the hepatitis B virus trans activator |
Q39077362 | Negative auto-regulators trap p53 in their web. |
Q45869640 | Negative effects of wild-type p53 and s-Myc on cellular growth and tumorigenicity of glioma cells. Implication of the tumor suppressor genes for gene therapy |
Q33740135 | Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. |
Q39007820 | Neomorphic mutations create therapeutic challenges in cancer. |
Q46821463 | Neoplastic transformation and angiogenesis in the thymus of transgenic mice expressing SV40 T and t antigen under an L-pyruvate kinase promoter (SV12 mice). |
Q26825296 | Neurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator |
Q36976531 | New Properties of Simian Virus 40 Large T Antigen |
Q54169975 | New aspects of cell biology in osteosarcoma. |
Q34047246 | New insights into p53 regulation and gene therapy for cancer. |
Q38389967 | New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy. |
Q41741132 | No requirement for src family kinases for PDGF signaling in fibroblasts expressing SV40 large T antigen |
Q94475905 | Non-disruptive mutation in TP53 DNA-binding domain is a beneficial factor of esophageal squamous cell carcinoma |
Q36969363 | Nonlytic Simian Virus 40-Specific 100K Phosphoprotein Is Associated with Anchorage-Independent Growth in Simian Virus 40-Transformed and Revertant Mouse Cell Lines |
Q36288245 | Nonselective expression of simian virus 40 large tumor antigen fragments in mouse cells |
Q40647696 | Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis |
Q36346972 | Nuclear antigen detected in hepatoma cell lines containing integrated hepatitis B virus DNA |
Q24310625 | Nuclear localization of the NS3 protein of hepatitis C virus and factors affecting the localization |
Q55282601 | Nuclear p53 Immunoreaction Associated with Poor Prognosis of Breast Cancer |
Q40818113 | Nuclear protein p68 is an RNA-dependent ATPase |
Q40115140 | Nuclear subcompartmentalization of simian virus 40 large T antigen: evidence for in vivo regulation of biochemical activities |
Q34115253 | ONYX-015: mechanisms of action and clinical potential of a replication-selective adenovirus |
Q40129645 | Oligomerization of oncoprotein p53. |
Q26830643 | Oncogenes and RNA splicing of human tumor viruses |
Q36874460 | Oncogenes and anti-oncogenes; the molecular basis of tumour behaviour |
Q41485266 | Oncogenes and antioncogenes in the development of HPV associated tumors |
Q35034093 | Oncogenes and tumor-suppressor genes |
Q39743389 | Oncogenes, cancer and analytical cytology |
Q26749382 | Oncogenic Intra-p53 Family Member Interactions in Human Cancers |
Q64517981 | Oncogenic intelligence: Cell immortalization and transformation by the p53 gene |
Q37857673 | One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor |
Q37817494 | Oral lichen planus and the p53 family: what do we know? |
Q39007931 | Osteocytes serve as a progenitor cell of osteosarcoma |
Q67970173 | Overexpression of p53 in head and neck cancer |
Q38045766 | Overexpression of p53 protein in human tumors |
Q43972822 | Overexpression of p73 causes apoptosis in vascular smooth muscle cells |
Q41489317 | Overexpression of the MDM2 oncogene in leukemia and lymphoma |
Q35992950 | Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma |
Q37058260 | Overlap of the p53-responsive element and cAMP-responsive element in the enhancer of human T-cell leukemia virus type I |
Q36897747 | Overproduction of protein p53 contributes to simian virus 40-mediated transformation |
Q41108776 | P53 Dysfunction in Neurodegenerative Diseases - The Cause or Effect of Pathological Changes? |
Q72350615 | P53 accumulation and proliferating-cell nuclear antigen expression in human lung cancer |
Q92732638 | P53 and The Immune Response: 40 Years of Exploration-A Plan for the Future |
Q53418486 | P53 and cyclin D1 staining patterns of malignant and premalignant oral lesions in age-dependent populations. |
Q44327720 | P53 family proteins provide new insights into lung carcinogenesis and clinical treatment |
Q26771603 | P53 functional abnormality in mesenchymal stem cells promotes osteosarcoma development |
Q40958072 | P53 gene mutations in lymphoid diseases and their possible relevance to drug resistance |
Q36216684 | P53 in cancer: a paradigm for modern management of cancer |
Q34546732 | P53 is a tumor suppressor gene |
Q34287830 | P53 mdm2 inhibitors |
Q33899383 | P53 mutation in acute T cell lymphoblastic leukemia is of somatic origin and is stable during establishment of T cell acute lymphoblastic leukemia cell lines. |
Q71219510 | P53 protein expression in pancreatic tumors and its relationship to clinicopathological factors and prognosis |
Q78792241 | P53 protein expression in transitional cell carcinoma of the bladder - experience of the University of Malaya Medical Centre |
Q33933630 | P53 transformation-related protein accumulates in the nucleus of transformed fibroblasts in association with the chromatin and is found in the cytoplasm of non-transformed fibroblasts |
Q28611354 | P53, apoptosis, and breast cancer |
Q28611435 | P53, cell cycle control and apoptosis: Implications for cancer |
Q36346951 | P80: a tumor-related protein found in many lymphomas of mice |
Q35832827 | Pancreatic adenocarcinomas frequently show p53 gene mutations. |
Q42065661 | Papillomavirus E7 oncoproteins share functions with polyomavirus small T antigens |
Q37680961 | Patented inhibitors of p53-Mdm2 interaction (2006 - 2008). |
Q41510725 | Pathways of p53-dependent apoptosis. |
Q33932090 | Permanent expression of p53 in FR 3T3 rat cells but cell cycle-dependent association with large-T antigen in simian virus 40 transformants |
Q40135384 | Phenotypic and Cytogenetic Characteristics of Human B-Lymphoid Cell Lines and Their Relevance for the Etiology of Burkitt'S Lymphoma |
Q54723898 | Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication. |
Q36781515 | Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells |
Q36933037 | Phosphorylation patterns of tumour antigens in cells lytically infected or transformed by simian virus 40 |
Q58073315 | Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73 |
Q36943796 | Polyoma Middle T Antigen Requires Cooperation from Another Gene to Express the Malignant Phenotype In Vivo |
Q27310118 | Polyoma small T antigen triggers cell death via mitotic catastrophe |
Q35013225 | Polyoma virus middle T antigen and its role in identifying cancer-related molecules |
Q38574112 | Polyomavirus BK and prostate cancer: a complex interaction of potential clinical relevance. |
Q36913417 | Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences. |
Q33336307 | Positive selection of candidate tumor-suppressor genes by subtractive hybridization |
Q74453662 | Possible Relation of p53 and mdm-2 Oncoprotein Expression in Thyroid Carcinoma: A Molecular-Pathological and Immunohistochemical Study on Paraffin-Embedded Tissue |
Q36966578 | Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells |
Q42754709 | Post-thymic T cell lymphomas frequently overexpress p53 protein but infrequently exhibit p53 gene mutations |
Q40528510 | Potential approaches for myocardial regeneration |
Q45878491 | Potential role of DNA polymerase beta in gene therapy against cancer: a case for colorectal cancer |
Q37349314 | Pre-crisis mouse cells show strain-specific covariation in the amount of 54-kilodalton phosphoprotein and in susceptibility to transformation by simian virus 40 |
Q35006968 | Precise epitope mapping of the murine transformation-associated protein, p53. |
Q36941888 | Presence in growth-arrested cells of cellular proteins that interact with simian virus 40 small-t antigen |
Q41366110 | Presence of human papillomavirus sequences in tumour-derived human oral keratinocytes expressing mutant p53 |
Q28240740 | Principles of tumor suppression |
Q59140486 | Production of a polyclonal antibody raised against recombinant flounder p53 protein |
Q87945234 | Profiling of Germline Mutations in Major Hotspot Codons of TP53 Using PCR-RFLP |
Q93001945 | Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma |
Q36135501 | Prognostic significance of p53 overexpression and mutation in colorectal adenocarcinomas |
Q34285565 | Prognostic significance of p53-expression in colorectal carcinoma as measured by a luminometric immunoassay |
Q52348330 | Programmed Cell Death, from a Cancer Perspective: An Overview. |
Q42499203 | Proliferative (MIB1, mdm2) Versus Anti-Proliferative (p53) Markers in Head and Neck Cancer. An Immunohistochemical Study |
Q39219310 | Promoter methylation of the SALL2 tumor suppressor gene in ovarian cancers |
Q34444393 | Prostate cancer in a transgenic mouse |
Q40964578 | Protein kinase CK2-dependent regulation of p53 function: evidence that the phosphorylation status of the serine 386 (CK2) site of p53 is constitutive and stable |
Q37514996 | Protein p53 and inducer-mediated erythroleukemia cell commitment to terminal cell division |
Q45966278 | Protein-to-protein interactions: criteria defining the assembly of the enamel organic matrix. |
Q35586902 | Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells |
Q36468283 | Proteomic approaches to the study of papillomavirus-host interactions. |
Q40462999 | Proto‐oncogenes and oncogenes in epidermal neoplasia |
Q33924762 | Purification and biochemical characterization of the Epstein-Barr virus-determined nuclear antigen and an associated protein with a 53,000-dalton subunit. |
Q41464734 | Purification and partial amino acid sequence analysis of the cellular tumour antigen, p53, from mouse SV40-transformed cells |
Q40214503 | Purification of p53/55 kinase from nuclear ribonucleoproteins of Namalwa cells |
Q47833426 | Putting p53 in Context |
Q36379182 | Quantitation and characterization of a species-specific and embryo stage-dependent 55-kilodalton phosphoprotein also present in cells transformed by simian virus 40 |
Q36973813 | Quantitation of a 55K Cellular Protein: Similar Amount and Instability in Normal and Malignant Mouse Cells |
Q36503933 | Quantitative Proteomic Analysis of Enriched Nuclear Fractions from BK Polyomavirus-Infected Primary Renal Proximal Tubule Epithelial Cells |
Q38147113 | RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response |
Q33928142 | Radioimmunoassay of the cellular protein p53 in mouse and human cell lines. |
Q35237803 | Rapid and sensitive quantitative immunoassay for the large simian virus 40 T antigen |
Q34360802 | Rearrangement of the p53 gene in human osteogenic sarcomas |
Q34469114 | Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus |
Q34441608 | Recombinant human MFG-E8 attenuates intestinal injury and mortality in severe whole body irradiation in rats |
Q36912292 | Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens |
Q39322285 | Regulation of Metabolic Activity by p53. |
Q33928759 | Regulation of SV40 DNA replication by phosphorylation of T antigen |
Q34252765 | Regulation of Viral Transcription and DNA Replication by the SV40 Large T Antigen |
Q35108767 | Regulation of p53 level by UBE4B in breast cancer |
Q36972504 | Regulation of the Cellular p53 Tumor Antigen in Teratocarcinoma Cells and Their Differentiated Progeny |
Q33943437 | Regulation of the G2/M transition by p53. |
Q33920419 | Relationship among Tau antigens isolated from various lines of simian virus 40-transformed cells |
Q28645822 | Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product |
Q36832377 | Requirements for species-specific papovavirus DNA replication. |
Q30329984 | Rescuing the function of mutant p53. |
Q45152311 | Resistance to viral infection of super p53 mice. |
Q36710840 | Restoration of wild-type p53 function in human cancer: relevance for tumor therapy. |
Q30831001 | Restoration of wild-type p53 function in human tumors: strategies for efficient cancer therapy. |
Q39169881 | Restoration of wild-type p53 in drug-resistant mouse breast cancer cells leads to differential gene expression, but is not sufficient to overcome the malignant phenotype. |
Q38213115 | Restoring the tumour suppressive function of p53 as a parallel strategy in melanoma therapy. |
Q36277435 | Restriction point control of cell growth by a labile protein: evidence for increased stability in transformed cells |
Q45203088 | Retinoblastoma in transgenic mice |
Q33693631 | Retinoblastoma in transgenic mice: models of hereditary retinoblastoma |
Q36692841 | Retinoblastoma protein and simian virus 40-dependent immortalization of human fibroblasts |
Q54033603 | Reversal of an antiestrogen-mediated cell cycle arrest of MCF-7 cells by viral tumor antigens requires the retinoblastoma protein-binding domain. |
Q39205536 | Reviving the guardian of the genome: Small molecule activators of p53. |
Q37690890 | Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer |
Q33603506 | Role of p53 assessment in management of Barrett's esophagus |
Q41515342 | Role of p53 in apoptosis. |
Q38883419 | Role of p53 isoforms and aggregations in cancer |
Q36941216 | Role of the p53 Protein in Cell Proliferation as Studied by Microinjection of Monoclonal Antibodies |
Q92257837 | Roles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation |
Q36400820 | Roles of the tumor suppressor p53 and the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in receptor-mediated apoptosis of WEHI 231 B lymphoma cells |
Q40936277 | Roots and perspectives of contemporary papillomavirus research |
Q24338301 | Rotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53 |
Q67240449 | SV40 Early mutants that are defective for viral DNA synthesis but competent for transformation of cultured rat and simian cells |
Q41396801 | SV40 T antigen and the exocytotic pathway |
Q59082218 | SV40 T antigen binds specifically to a cellular 53 K protein in vitro |
Q38295645 | SV40 T-antigen as a dual oncogene: structure and function of the plasma membrane-associated population |
Q72646037 | SV40 antitumor sera that directly immunoprecipitate small-t-associated cellular proteins |
Q28282761 | SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation |
Q47289313 | SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000. |
Q43749432 | SV40-transformed cells express SV40 T antigen-related antigens on the cell surface |
Q37345587 | SV40: Cell transformation and tumorigenesis |
Q38072351 | Senescence regulation by the p53 protein family |
Q35237665 | Separation of lytic and transforming functions of the simian virus 40 A region: two mutants which are temperature sensitive for lytic functions have opposite effects on transformation |
Q36854935 | Sequences from polyomavirus and simian virus 40 large T genes capable of immortalizing primary rat embryo fibroblasts |
Q35688697 | Sequential stimulation of cellular RNA synthesis in polyoma-infected mouse kidney cell cultures |
Q36924904 | Signal-dependent translocation of simian virus 40 large-T antigen into rat liver nuclei in a cell-free system |
Q39748728 | Simian Virus 40 Infection of Humans |
Q36686025 | Simian virus 40 (SV40) T-antigen mutations in tumorigenic transformation of SV40-immortalized human uroepithelial cells |
Q33292433 | Simian virus 40 T antigen can regulate p53-mediated transcription independent of binding p53. |
Q36802646 | Simian virus 40 T antigen can transcriptionally activate and mediate viral DNA replication in cells which lack the retinoblastoma susceptibility gene product |
Q37333985 | Simian virus 40 T-antigen-mediated gene regulation in enterocytes is controlled primarily by the Rb-E2F pathway |
Q40307810 | Simian virus 40 T-antigen-related cell surface antigen: serological demonstration on simian virus 40-transformed monolayer cells in situ |
Q40307207 | Simian virus 40 T-antigen: identification of tryptic peptides in the C-terminal region and definition of the reading frame |
Q36797245 | Simian virus 40 can overcome the antiproliferative effect of wild-type p53 in the absence of stable large T antigen-p53 binding |
Q35236017 | Simian virus 40 gene A regulation of cellular DNA synthesis. II. In nonpermissive cells |
Q36832198 | Simian virus 40 host range/helper function mutations cause multiple defects in viral late gene expression |
Q24308996 | Simian virus 40 large T antigen affects the Saccharomyces cerevisiae cell cycle and interacts with p34CDC28 |
Q35831951 | Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts |
Q36854039 | Simian virus 40 large T antigen oligomers: analysis of electrophoresis in the absence of detergent |
Q40064685 | Simian virus 40 large T antigen stably complexes with a 185-kilodalton host protein |
Q24305356 | Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1 |
Q36945232 | Simian virus 40 large T-antigen point mutants that are defective in viral DNA replication but competent in oncogenic transformation |
Q40108931 | Simian virus 40 large T-antigen-dependent DNA replication is activated by protein phosphatase 2A in vitro. |
Q36688604 | Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products |
Q42599235 | Simian virus 40 mutants with amino-acid substitutions near the amino terminus of large T antigen |
Q36855375 | Simian virus 40 origin DNA-binding domain on large T antigen. |
Q36905896 | Simian virus 40 sequences between 0.168 and 0.424 map units are not required for abortive transformation |
Q39876425 | Simian virus 40 small t antigen activates the carboxyl-terminal transforming p53-binding domain of large T antigen. |
Q36906843 | Simian virus 40 tumor antigen: isolation of the origin-specific DNA-binding domain |
Q34255887 | Simian virus 40-transformed cells express new species of proteins precipitable by anti-simian virus 40 tumor serum |
Q45734015 | Simian virus-40 infection inhibits DNA damage-induced enhancement of CD95 expression and function. |
Q38993512 | SirT3 and p53 Deacetylation in Aging and Cancer |
Q36902524 | Site-directed mutagenesis of the simian virus 40 large T-antigen gene: replication-defective amino acid substitution mutants that retain the ability to induce morphological transformation |
Q37142905 | Small DNA tumor viruses: large contributors to biomedical sciences |
Q64374754 | Small size, big impact: how studies of small DNA tumour viruses revolutionized biology |
Q34714730 | Small tumor antigen of polyomaviruses: role in viral life cycle and cell transformation |
Q24651380 | Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy |
Q27014977 | Smoking, p53 mutation, and lung cancer |
Q33964955 | Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40 |
Q67290242 | Specific DNA binding activity of T antigen subclasses varies among different SV40-transformed cell lines |
Q40141165 | Specific interaction of simian virus 40 large T antigen with cellular chromatin and nuclear matrix during the course of infection |
Q72924819 | Specific interaction of the SV40 T antigen-cellular p53 protein complex with SV40 DNA |
Q33999909 | Split T cell tolerance against a self/tumor antigen: spontaneous CD4+ but not CD8+ T cell responses against p53 in cancer patients and healthy donors |
Q36780095 | Spontaneous rearrangement of integrated simian virus 40 DNA in nine transformed rodent cell lines |
Q38335406 | Sprouty 2 binds ESCRT-II factor Eap20 and facilitates HIV-1 gag release |
Q41020740 | Stabilization of p53 by adenovirus E1A occurs through its amino-terminal region by modification of the ubiquitin-proteasome pathway |
Q36936688 | Stabilization of the 53,000-Dalton Nonviral Tumor Antigen Is Not Required for Transformation by Simian Virus 40 |
Q36907734 | Stabilization of the large T protein in temperature-independent (type A) FR 3T3 rat cells transformed with the simian virus 40 tsA30 mutant |
Q40040456 | Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: influence of viral and cellular factors and biological consequences |
Q36730106 | Stoichiometry of cellular and viral components in the polyomavirus middle-T antigen-tyrosine kinase complex |
Q36932873 | Stoichiometry of large T antigen and pp53 in complexes isolated from simian virus 40-transformed rat cells |
Q34076012 | Strategies for manipulating the p53 pathway in the treatment of human cancer. |
Q37794096 | Stressin' Sestrins take an aging fight |
Q36882128 | Structural analysis of a hepatitis B virus genome integrated into chromosome 17p of a human hepatocellular carcinoma |
Q41792117 | Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53. |
Q41428303 | Structural prerequisites of simian virus 40 large T antigen for the maintenance of cell transformation |
Q36924945 | Structure and biochemical functions of four simian virus 40 truncated large-T antigens |
Q36927941 | Structure and synthesis of a simian virus 40 super T-antigen |
Q36931075 | Study of the Functional Activities Concomitantly Retained by the 115,000 M r Super T Antigen, an Evolutionary Variant of Simian Virus 40 Large T Antigen Expressed in Transformed Rat Cells |
Q41484312 | Studying the interaction of polyoma virus middle T antigen with cellular proteins |
Q41648413 | Suppression of human nasopharyngeal carcinoma cell growth in nude mice by the wild-type p53 gene |
Q36350167 | Suppression of in vivo tumor formation induced by simian virus 40-transformed cells in mice receiving antiidiotypic antibodies. |
Q44910351 | Suppression of platelet-derived growth factor alpha- and beta-receptor mRNA levels in human fibroblasts by SV40 T/t antigen |
Q80212337 | Suppressive effects of antiandrogens, finasteride and flutamide on development of prostatic lesions in a transgenic rat model |
Q35967111 | Surf the post-translational modification network of p53 regulation |
Q31904803 | Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha |
Q45798213 | Synthesis and processing of simian virus 40-specific RNA in adenovirus-infected, simian virus 40-transformed human cells |
Q44247769 | Systemic lupus erythematosus and uterine cervical neoplasia |
Q24645091 | T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus |
Q34662543 | T antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesis |
Q36900316 | T-antigen-DNA polymerase alpha complex implicated in simian virus 40 DNA replication |
Q55483973 | TP53 Gene Mutations and 17p Deletions in Human Astrocytomas |
Q36081911 | TP53 gene mutations and protein accumulation in primary vaginal carcinomas |
Q36135944 | TP53 mutation analyses on breast carcinomas: a study of paraffin-embedded archival material |
Q38199075 | TP53 mutations in human cancer: database reassessment and prospects for the next decade |
Q34559185 | TP53 mutations in nonsmall cell lung cancer |
Q40742654 | TP53 tumor-suppressor gene and human carcinogenesis |
Q46408321 | TP63 mutations are frequent in cutaneous melanoma, support UV etiology, but their role in melanomagenesis is unclear. |
Q33937962 | Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins |
Q33655329 | Targeting p53 for Novel Anticancer Therapy |
Q37177586 | Targeting the MDM2-p53 interaction for cancer therapy |
Q91643844 | Targeting the Oncogenic p53 Mutants in Colorectal Cancer and Other Solid Tumors |
Q35795073 | Targeting the p53 signaling pathway in cancer therapy - the promises, challenges and perils |
Q33657519 | Targeting tumor suppressor networks for cancer therapeutics |
Q36831228 | Temperature-sensitive mutants identify crucial structural regions of simian virus 40 large T antigen |
Q40722479 | The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis. |
Q24300207 | The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53 |
Q34246710 | The DNA damage response in viral-induced cellular transformation |
Q37785502 | The DNA damage response—Repair or despair? |
Q91816686 | The Diverse Functions of Mutant 53, Its Family Members and Isoforms in Cancer |
Q35851139 | The Epstein-Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin-dependent kinase inhibitors |
Q33817088 | The Epstein-Barr virus protein BRLF1 activates S phase entry through E2F1 induction |
Q42323049 | The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants |
Q50448531 | The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene. |
Q55180659 | The Guardian of the Genome Revisited: p53 Downregulates Genes Required for Telomere Maintenance, DNA Repair, and Centromere Structure. |
Q24317677 | The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 |
Q28079490 | The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions |
Q36430168 | The P53 pathway: what questions remain to be explored? |
Q38896065 | The Paradox of p53: What, How, and Why? |
Q34549700 | The Promise of Proteomics in the Study of Oncogenic Viruses |
Q41528803 | The Retinoblastoma Protein: A Master Regulator of Cell Cycle, Differentiation and Apoptosis |
Q40271232 | The SV40 a gene product is required for the production of a 54,000 MW cellular tumor antigen |
Q36827839 | The ability of large T antigen to complex with p53 is necessary for the increased life span and partial transformation of human cells by simian virus 40. |
Q33932011 | The abnormal location of cytoplasmic SV40 large T is not caused by failure to bind to DNA or to p53. |
Q38186535 | The aggregation of mutant p53 produces prion-like properties in cancer |
Q40039307 | The amino-terminal functions of the simian virus 40 large T antigen are required to overcome wild-type p53-mediated growth arrest of cells. |
Q31816068 | The angiotensin II-dependent nuclear translocation of Stat1 is mediated by the Jak2 protein motif 231YRFRR. |
Q53542021 | The cellular oncogene p53 can be activated by mutagenesis. |
Q40627208 | The clinical relevance of the p53 tumour suppressor gene |
Q36764924 | The clinical significance of autoantibodies in gastrointestinal malignancies: an overview |
Q40381238 | The clinical significance of p53 aberrations in human tumours |
Q34903861 | The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53. |
Q35191541 | The complex interactions of p53 with target DNA: we learn as we go. |
Q43941701 | The conformationally flexible S9-S10 linker region in the core domain of p53 contains a novel MDM2 binding site whose mutation increases ubiquitination of p53 in vivo |
Q37808166 | The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication |
Q37859721 | The dual role of p53: DNA protection and antioxidant. |
Q34402080 | The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth |
Q33593937 | The emerging p53 gene family |
Q26742058 | The expanding regulatory universe of p53 in gastrointestinal cancer |
Q24645732 | The first 30 years of p53: growing ever more complex |
Q34180336 | The genetics and genomics of cancer |
Q40279927 | The genome of human papovavirus BKV |
Q34142403 | The history of p53. A perfect example of the drawbacks of scientific paradigms |
Q24610004 | The history of tumor virology |
Q33888765 | The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis |
Q39595067 | The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator CBP/p300. |
Q40138359 | The immunopathology of SV40-induced transformation |
Q40088889 | The impact of p53 on the early stage replication of retrovirus. |
Q39729519 | The implications of embryonic gene expression in neoplasia |
Q37182764 | The individualization of cancer therapy: the unexpected role of p53. |
Q41690979 | The initiation of simian virus 40 DNA replication in vitro |
Q28252021 | The interaction of the hnRNP family member E1B-AP5 with p53 |
Q33693832 | The isoforms of the p53 protein |
Q36832483 | The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions |
Q92701432 | The many faces of p53: something for everyone |
Q36659029 | The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth |
Q40076287 | The mechanism of cell transformation by SV40 and Polyoma virus |
Q40867777 | The molecular and genetic characterization of human soft tissue tumors. |
Q92062954 | The multiple mechanisms that regulate p53 activity and cell fate |
Q40605944 | The origins of the small DNA tumor viruses |
Q28259725 | The p53 circuit board |
Q36781766 | The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigen |
Q36521923 | The p53 family in nervous system development and disease |
Q48678761 | The p53 family: guardians of maternal reproduction |
Q40961528 | The p53 gene and its role in human brain tumors. |
Q53601235 | The p53 knowledgebase: an integrated information resource for p53 research. |
Q67469552 | The p53 tumor suppressor gene. A preliminary clinical study in breast cancer patients |
Q37887629 | The p53 tumor suppressor protein regulates hematopoietic stem cell fate |
Q37751892 | The p53 tumour suppressor gene |
Q38548852 | The p53 tumour suppressor gene |
Q34187832 | The p53 tumour suppressor protein |
Q33922153 | The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II. |
Q41489275 | The p53-Bcl-2 connection |
Q37503463 | The p53-MDM2/MDMX axis - A chemotype perspective |
Q35371834 | The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation |
Q40130414 | The pathogenesis of Abelson virus lymphomas of the mouse |
Q62497458 | The predictive power of semiquantitative immunohistochemical assessment of p53 and c-erb B-2 in lymph node-negative breast cancer |
Q53560080 | The presence of p53 transformation-related protein in Ab-MuLV transformed cells is required for their development into lethal tumors in mice |
Q72314536 | The prevalence of different human papillomavirus types and p53 mutations in laryngeal carcinomas: is there a reciprocal relationship? |
Q51342055 | The prognostic implication of the expression of EGFR, p53, cyclin D1, Bcl-2 and p16 in primary locally advanced oral squamous cell carcinoma cases: a tissue microarray study. |
Q35978470 | The prognostic significance of the accumulation of p53 tumour-suppressor gene protein in gastric adenocarcinoma |
Q34629128 | The rapidly expanding family of human polyomaviruses: recent developments in understanding their life cycle and role in human pathology |
Q42125689 | The relationship of p53 immunostaining to survival in carcinoma of the lung |
Q72700246 | The relationship of p53 protein and lymph node metastases in invasive breast cancer |
Q41193565 | The role of DNA repair in the prevention of cancer |
Q78244648 | The role of autosomal cell apoptosis regulator genes in human spermatogenesis |
Q24793695 | The role of circulating anti-p53 antibodies in patients with advanced non-small cell lung cancer and their correlation to clinical parameters and survival |
Q53569200 | The role of gene dosage and genetic transpositions in carcinogenesis |
Q35034088 | The role of non-ras transforming genes in chemical carcinogenesis |
Q41176248 | The role of p53 in cell cycle regulation |
Q41486644 | The role of p53 in growth of mouse fibroblast lines |
Q34283469 | The role of p53 in human cancer |
Q33807833 | The role of the E6-p53 interaction in the molecular pathogenesis of HPV. |
Q34602545 | The significance of immunohistochemistry in the diagnosis and therapy of neoplasms |
Q45801434 | The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins |
Q37537138 | The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines |
Q33938629 | The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein |
Q40276689 | The transforming genes of SV40 and polyoma |
Q41457444 | The transforming protein of the MC29-related virus CMII is a nuclear DNA-binding protein whereas MH2 codes for a cytoplasmic RNA-DNA binding polyprotein |
Q33490078 | The tsA58 simian virus 40 large tumor antigen disrupts megakaryocyte differentiation in transgenic mice. |
Q38314522 | The tumor suppressor p53 and the oncoprotein simian virus 40 T antigen bind to overlapping domains on the MDM2 protein |
Q40677778 | The tumor suppressor p53 is bound to RNA by a stable covalent linkage |
Q28131694 | The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest |
Q33384295 | The ubiquitin system, disease, and drug discovery |
Q33566355 | The v-rel oncogene product is complexed to a 40-kDa phosphoprotein in transformed lymphoid cells |
Q36779984 | The zinc finger region of simian virus 40 large T antigen |
Q36695049 | The zinc finger region of simian virus 40 large T antigen is needed for hexamer assembly and origin melting |
Q84961734 | Therapeutic options for treatment of Merkel cell carcinoma |
Q38042630 | Therapeutic strategies for head and neck cancer based on p53 status |
Q91898958 | Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia |
Q47742599 | Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others |
Q33302913 | Thirty years into the genomics era: tumor viruses led the way. |
Q37188430 | Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222 |
Q36926635 | Time-dependent maturation of the simian virus 40 large T antigen-p53 complex studied by using monoclonal antibodies |
Q28255819 | To die or not to die: how does p53 decide? |
Q34983824 | To kill or be killed: viral evasion of apoptosis |
Q34979520 | Topoisomerase activity associated with SV40 large tumor antigen |
Q38486723 | Toxicological and pathological applications of proliferating cell nuclear antigen (PCNA), a novel endogenous marker for cell proliferation |
Q35127707 | Transactivation of Human cdc2 Promoter by Adenovirus E1A |
Q27679224 | Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code |
Q38341700 | Transcription factor E4TF1 contains two subunits with different functions |
Q36777349 | Transcription regulation by mutant p53. |
Q39005896 | Transcriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53. |
Q37113939 | Transcriptional and Transforming Activities of the Adenovirus E1A Proteins |
Q38408993 | Transcriptome profiling the gills of amoebic gill disease (AGD)-affected Atlantic salmon (Salmo salar L.): a role for tumor suppressor p53 in AGD pathogenesis? |
Q36217854 | Transfection of neonatal rat Schwann cells with SV-40 large T antigen gene under control of the metallothionein promoter |
Q41601530 | Transformation and radiosensitivity of human diploid skin fibroblasts transfected with SV40 T-antigen mutants defective in RB and P53 binding domains |
Q44840448 | Transformation and radiosensitivity of human diploid skin fibroblasts transfected with activated ras oncogene and SV40 T-antigen |
Q40307671 | Transformation of Primary Hamster Brain Cells with JC Virus and Its DNA |
Q36919634 | Transformation of precrisis human cells by the simian virus 40 cytoplasmic-localization mutant pSVCT3 is accompanied by nuclear T antigen |
Q40106989 | Transformation-Associated Tumor Antigens |
Q41505517 | Transforming growth factor-beta 1 enhances serum-induced dephosphorylation of the P53 protein in cell lines growth-inhibited by this factor |
Q83169251 | Transgenic models for prostate cancer research |
Q34164124 | Transgenic models of retinoblastoma: what they tell us about its cause and treatment |
Q47973774 | Transgenic rodent mutation/cancer bioassays: cell cycle control, cell proliferation and apoptosis as modifiers of outcome |
Q80221850 | Treatment options for the recurrent odontogenic keratocyst |
Q35902311 | Truncated N-terminal mutants of SV40 large T antigen as minimal immortalizing agents for CNS cells |
Q34324683 | Tumor protein p53 (TP53) testing and Li-Fraumeni syndrome : current status of clinical applications and future directions |
Q38026794 | Tumor suppressive pathways in the control of neurogenesis. |
Q37289549 | Tumor suppressor genes and cancer of the human nervous system |
Q41625163 | Tumor suppressor genes and human cancer |
Q40568049 | Tumor suppressor genes and their roles in breast cancer |
Q40456928 | Tumor suppressor genes in human thyroid neoplasms: p53 mutations are associated undifferentiated thyroid cancers |
Q36847017 | Tumor suppressor genes: a new era for molecular genetic studies of cancer |
Q53449845 | Tumor suppressor p53 gene forms multiple isoforms: evidence for single locus origin and cytoplasmic complex formation with heat shock proteins. |
Q34314048 | Tumor suppressor p53 mutations and breast cancer: a critical analysis |
Q40130058 | Tumor viruses and early mouse embryos |
Q38824332 | Tumor-Suppressor Functions of the TP53 Pathway |
Q30499489 | Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancers |
Q41575783 | Tumorigenic conversion of human mesothelial cells as a consequence of platelet-derived growth factor-A chain overexpression |
Q40044331 | Tumorigenicity by human papillomavirus type 16 E6 and E7 in transgenic mice correlates with alterations in epithelial cell growth and differentiation. |
Q41809596 | Tumourigenesis associated with the p53 tumour suppressor gene |
Q48033225 | Turning the key on p53. |
Q33807787 | Twenty years of p53 research: structural and functional aspects of the p53 protein |
Q36980764 | Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53 |
Q44676897 | Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virus |
Q36896709 | Two classes of transformation-deficient, immortalization-positive simian virus 40 mutants constructed by making three-base insertions in the T antigen gene |
Q59074470 | Two different viral transforming proteins bind the same host tumour antigen |
Q33865112 | Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin? |
Q40129418 | Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen. |
Q22251289 | Two genetic hits (more or less) to cancer |
Q36887574 | Two integrated partial repeats of simian virus 40 together code for a super-T antigen |
Q24609948 | UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells |
Q27015641 | Uncovering the role of p53 splice variants in human malignancy: a clinical perspective |
Q64236647 | Understanding p53 functions through p53 antibodies |
Q37680206 | Unequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity |
Q34322386 | Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? |
Q36743177 | Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens |
Q34110697 | Update on human polyomaviruses and cancer |
Q47111189 | Updates from the TP53 universe |
Q34170074 | Vaccines and immunotherapeutics for the treatment of malignant disease |
Q37496628 | Variability in APOE genotype status in human-derived cell lines: a cause for concern in cell culture studies? |
Q37087404 | Versatile functions of p53 protein in multicellular organisms |
Q33894872 | View and review on viral oncology research |
Q41708689 | Viral and cellular oncogene expression during progressive malignant transformation of SV40 transformed human fibroblasts |
Q33846198 | Viral carcinogenesis: revelation of molecular mechanisms and etiology of human disease |
Q44491628 | Viral genotypes and p53 expression in Epstein-Barr virus-associated primary malignant lymphomas of the intestines |
Q41510729 | Viral inhibitors of apoptosis |
Q24538223 | Viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM19, and inhibits interferon/retinoic acid-induced cell death. |
Q39576424 | Viral oncoproteins discriminate between p53 and the p53 homolog p73. |
Q41374895 | Virocrine transformation |
Q36318145 | Viruses - seeking and destroying the tumor program |
Q30384388 | Viruses and human cancers: a long road of discovery of molecular paradigms. |
Q24653900 | Viruses associated with human cancer |
Q36304840 | Visualizing viral protein structures in cells using genetic probes for correlated light and electron microscopy |
Q73066904 | WAF1 expression and p53 mutations in human colorectal cancers |
Q38043443 | What We Know about the Molecular Genetics of Central Nervous System (CNS) Tumours in Malaysia |
Q91771327 | What's knowledge is prologue: celebrating the 40th anniversary of the p53 discovery |
Q37582777 | When mutants gain new powers: news from the mutant p53 field. |
Q37788083 | Whether to target single or multiple CDKs for therapy? That is the question |
Q37811898 | Why do viruses cause cancer? Highlights of the first century of human tumour virology |
Q35830939 | Widespread p53 overexpression in human malignant tumors. An immunohistochemical study using methacarn-fixed, embedded tissue |
Q36618628 | Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9 |
Q44703400 | Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication |
Q40872252 | Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA. |
Q39822156 | Wild-type p53 enhances efficiency of simian virus 40 large-T-antigen-induced cellular transformation |
Q40043948 | Wild-type p53 is not a negative regulator of simian virus 40 DNA replication in infected monkey cells. |
Q26999402 | Zebrafish sex: a complicated affair |
Q90108778 | Zinc-finger protein p52-ZER6 accelerates colorectal cancer cell proliferation and tumour progression through promoting p53 ubiquitination |
Q73571149 | [An immunohistochemistry study of p53 protein in squamous cell carcinoma of the larynx] |
Q80076298 | [Molecular biological and immunohistochemical analysis of tp53 in human ameloblastomas] |
Q90070454 | [Update on Li-Fraumeni syndrome] |
Q33807825 | mdm2: a bridge over the two tumour suppressors, p53 and Rb. |
Q28565821 | p300 family members associate with the carboxyl terminus of simian virus 40 large tumor antigen |
Q35326348 | p53 Family: Role of Protein Isoforms in Human Cancer |
Q90510724 | p53 Overexpression in Oral Mucosa in Relation to Shisha Smoking in Syria and Lebanon |
Q41313953 | p53 Phosphorylation: biochemical and functional consequences |
Q34313764 | p53 Research: the past thirty years and the next thirty years. |
Q73215749 | p53 abnormalities are rare events in neuroendocrine (Merkel cell) carcinoma of the skin. An immunohistochemical and SSCP analysis |
Q72680112 | p53 accumulation in polynuclear-giant-cells |
Q44581576 | p53 and DNA polymerase alpha compete for binding to SV40 T antigen |
Q35185411 | p53 and E2F-1 cooperate to mediate apoptosis |
Q33853843 | p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes |
Q38294077 | p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches |
Q37502697 | p53 and little brother p53/47: linking IRES activities with protein functions |
Q55002919 | p53 and metabolism: from mechanism to therapeutics. |
Q36915110 | p53 and retinoblastoma pathways in bladder cancer. |
Q55084411 | p53 and the Viral Connection: Back into the Future ‡. |
Q37242078 | p53 as a therapeutic target. |
Q36356298 | p53 attenuates AKT signaling by modulating membrane phospholipid composition |
Q37619644 | p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression. |
Q42281236 | p53 expression and its relationship to DNA alterations in bone and soft tissue sarcomas |
Q74122440 | p53 expression and p53 gene mutation in oral cancer and dysplasia |
Q41947345 | p53 expression in colorectal tumors. |
Q71603631 | p53 expression in odontogenic keratocyst epithelium |
Q44259985 | p53 expression is common in malignant mesothelioma |
Q34206213 | p53 functional assays: detecting p53 mutations in both the germline and in sporadic tumours |
Q34254691 | p53 functions as a cell cycle control protein in osteosarcomas |
Q40370722 | p53 gene mutations and photocarcinogenesis |
Q48428560 | p53 gene mutations in primary lung tumors are conserved in brain metastases |
Q42787579 | p53 gene mutations, p53 protein accumulation and compartmentalization in colorectal adenocarcinoma |
Q36079809 | p53 immunohistochemistry as an independent prognostic factor for superficial transitional cell carcinoma of the bladder |
Q42281269 | p53 immunoreaction in endoscopic biopsy specimens of colorectal cancer, and its prognostic significance |
Q73130677 | p53 immunostaining and image cytometry DNA analysis in precancerous and cancerous squamous epithelial lesions of the larynx |
Q33358202 | p53 in cell invasion, podosomes, and invadopodia |
Q35982948 | p53 in colorectal cancer: clinicopathological correlation and prognostic significance |
Q77957211 | p53 induction in normal human skin in vitro following exposure to solar simulated UV and UV-B irradiation |
Q24319034 | p53 isoforms can regulate p53 transcriptional activity. |
Q91701515 | p53 modifications: exquisite decorations of the powerful guardian |
Q33750337 | p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer |
Q36690312 | p53 mutations are not selected for in simian virus 40 T-antigen-induced tumors from transgenic mice |
Q36622335 | p53 mutations in urinary bladder cancer. |
Q49164152 | p53 mutations occur in clinical, but not latent, human prostate carcinoma |
Q41607022 | p53 mutations, methylation and genomic instability in the progression of chronic myeloid leukaemia |
Q48243360 | p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways. |
Q40848687 | p53 overexpression in Ewing's sarcoma/primitive neuroectodermal tumour is an uncommon event |
Q53559051 | p53 protein and control of growth. |
Q55483225 | p53 protein expression in central nervous system tumors: an immunohistochemical study with CM1 polyvalent and DO-7 monoclonal antibodies. |
Q72046282 | p53 protein expression in cutaneous T-cell lymphomas |
Q73144803 | p53 protein expression in ductal carcinoma in situ (DCIS) of the breast |
Q35994464 | p53 protein expression in human breast carcinoma: relationship to expression of epidermal growth factor receptor, c-erbB-2 protein overexpression, and oestrogen receptor |
Q36294933 | p53 protein expression in nephroblastomas: a predictor of poor prognosis |
Q37107115 | p53 protein in odontogenic cysts: increased expression in some odontogenic keratocysts |
Q45122733 | p53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation. |
Q37821711 | p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells |
Q35329162 | p53 transformation-related protein: detection by monoclonal antibody in mouse and human cells |
Q35360570 | p53 transformation-related protein: detection of an associated phosphotransferase activity |
Q42440449 | p53 tumor suppressor gene protein expression in premalignant and malignant skin lesions of kidney transplant recipients |
Q37049524 | p53 tumor suppressor gene: a critical molecular target for UV induction and prevention of skin cancer |
Q41640484 | p53 tumor-suppressor gene: clues to molecular carcinogenesis |
Q89783061 | p53's Extended Reach: The Mutant p53 Secretome |
Q47702659 | p53, Bax and Bcl-2 expression, and apoptosis in gestational trophoblast of complete hydatidiform mole |
Q42362115 | p53, SKP2, and DKK3 as MYCN Target Genes and Their Potential Therapeutic Significance |
Q35103179 | p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome |
Q37610416 | p53, a transformation-related cellular-encoded protein, can be used as a biochemical marker for the detection of primary mouse tumor cells |
Q38102472 | p53-based therapeutics for head and neck squamous cell carcinoma |
Q40873109 | p53-catalyzed annealing of complementary single-stranded nucleic acids |
Q34305233 | p53-dependent apoptosis pathways. |
Q34424487 | p53-dependent growth arrest of REF52 cells containing newly amplified DNA. |
Q34609247 | p53-mediated cellular response to DNA damage in cells with replicative hepatitis B virus |
Q36443527 | p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. |
Q24338379 | p53: 25 years after its discovery |
Q94671691 | p53: 800 million years of evolution and 40 years of discovery |
Q40564007 | p53: a cellular Achilles' heel revealed. |
Q37248542 | p53: a molecular marker for the detection of cancer. |
Q91651435 | p53: a tumor suppressor hiding in plain sight |
Q45888635 | p53: balancing tumour suppression and implications for the clinic |
Q83365205 | p53: more research and more questions |
Q91771321 | p53: not just a tumor suppressor |
Q37824262 | p53: the attractive tumor suppressor in the cancer research field |
Q36163707 | p53: twenty five years understanding the mechanism of genome protection |
Q30595453 | p63 and p73: old members of a new family |
Q35227440 | p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53. |
Q40774641 | p73 is a growth-regulated protein in vascular smooth muscle cells and is present at high levels in human atherosclerotic plaque |
Q39589009 | pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression |
Q40650649 | trans activation of type 1 interferon promoters by simian virus 40 T antigen |
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