Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells

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Mutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...885624Z
P356DOI10.1371/JOURNAL.PONE.0085624
P932PMC publication ID3874028
P698PubMed publication ID24386484
P5875ResearchGate publication ID259567479

P2093author name stringYanhong Zhang
Xinbin Chen
Wensheng Yan
P2860cites workEffects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domainsQ51186530
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndromeQ52561781
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Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapyQ77932308
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndromeQ81166001
Sarcomatoid renal cell carcinoma is an example of epithelial–mesenchymal transitionQ82047838
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathwayQ24302433
p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinomaQ24306453
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
Role of DeltaNp63gamma in epithelial to mesenchymal transitionQ24632945
MDCK Cystogenesis Driven by Cell Stabilization within Computational AnaloguesQ27333596
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutationsQ27730815
Complex networks orchestrate epithelial-mesenchymal transitionsQ29547478
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 databaseQ29616468
Tumor spectrum analysis in p53-mutant miceQ29617436
T antigen is bound to a host protein in SY40-transformed cellsQ29618321
p53: puzzle and paradigmQ29618407
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancerQ30525287
Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasionQ30537354
Interaction of the human papillomavirus type 16 E6 oncoprotein with wild-type and mutant human p53 proteinsQ33292223
Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancerQ33607176
The p53 pathwayQ33643359
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Scatter factors and invasive growthQ34231968
Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genesQ34292432
The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growthQ34402080
Database of p53 gene somatic mutations in human tumors and cell linesQ34868968
Mutant p53 Disrupts MCF-10A Cell Polarity in Three-dimensional Culture via Epithelial-to-mesenchymal TransitionsQ34963520
The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein.Q35782290
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.Q36660357
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomesQ36777326
Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.Q36993572
P63 regulates tubular formation via epithelial-to-mesenchymal transitionQ36998524
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When mutants gain new powers: news from the mutant p53 field.Q37582777
p53 and its mutants in tumor cell migration and invasionQ37832072
Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.Q38291171
Spatial repression of PCNA by p53 during kidney developmentQ38363218
Early organogenesis of the kidneyQ39611879
Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.Q39670597
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of SlugQ39850223
Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy.Q39966300
C-Met Proto-Oncogene Expression in Benign and Malignant Human Renal TissuesQ40883469
Modulation of scatter factor/hepatocyte growth factor activity by cell-substratum adhesionQ41472012
Chromosome 17p deletions and p53 mutations in renal cell carcinoma.Q41545285
p53 tumor-suppressor gene: Clues to molecular carcinogenesisQ41640484
Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cellsQ42416957
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse developmentQ42770153
Induction of gene amplification as a gain-of-function phenotype of mutant p53 proteinsQ44010460
P53 mutations and other prognostic factors of renal cell carcinomaQ44307459
Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures.Q46150566
Rising incidence of renal cell cancer in the United StatesQ46854143
TP53 gene mutations in canine osteosarcomaQ47643652
Value of p53 as a prognostic marker in histologic subtypes of renal cell carcinoma: a systematic analysis of primary and metastatic tumor tissueQ47794980
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e85624
P577publication date2013-12-27
P1433published inPLOS OneQ564954
P1476titleMutant p53 cooperates with knockdown of endogenous wild-type p53 to disrupt tubulogenesis in Madin-Darby canine kidney cells
P478volume8

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cites work (P2860)
Q48162761Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity.
Q35987262P73 tumor suppressor and its targets, p21 and PUMA, are required for madin-darby canine kidney cell morphogenesis by maintaining an appropriate level of epithelial to mesenchymal transition
Q38746401Regulation of the MET oncogene: molecular mechanisms
Q35827656The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition
Q55515332p53-Dependent and -Independent Epithelial Integrity: Beyond miRNAs and Metabolic Fluctuations.

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