| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1014813589 |
| P356 | DOI | 10.1038/SJ.ONC.1202867 |
| P698 | PubMed publication ID | 10490818 |
| P5875 | ResearchGate publication ID | 12809037 |
| P2093 | author name string | Sirma H | |
| Giannini C | |||
| Bréchot C | |||
| Kremsdorf D | |||
| Paterlini P | |||
| Poussin K | |||
| P2860 | cites work | Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation | Q24310197 |
| Expression of the papillomavirus E2 protein in HeLa cells leads to apoptosis | Q24532089 | ||
| Hepatitis B virus X protein interacts with a probable cellular DNA repair protein | Q24676695 | ||
| Dengue virus replication in human hepatoma cells activates NF-kappaB which in turn induces apoptotic cell death | Q27480811 | ||
| Hepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alpha | Q27485874 | ||
| p53: puzzle and paradigm | Q29618407 | ||
| Suppression of TNF-alpha-induced apoptosis by NF-kappaB | Q29618717 | ||
| Hepatitis B virus HBx protein deregulates cell cycle checkpoint controls | Q33765576 | ||
| Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines | Q33782708 | ||
| The hepatitis B virus X protein targets the basic region-leucine zipper domain of CREB. | Q34382034 | ||
| Hepadnaviral X Protein:Review of Recent Progress | Q34450047 | ||
| Hepatitis B virus transactivator protein X interacts with the TATA-binding protein. | Q34673509 | ||
| Genetic heterogeneity of hepatocellular carcinoma | Q35004899 | ||
| Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3 | Q35101216 | ||
| Hepatitis B virus HBx protein activates Ras-GTP complex formation and establishes a Ras, Raf, MAP kinase signaling cascade | Q35850088 | ||
| Review: hepatitis B virus X-gene product: a promiscuous transcriptional activator | Q36100142 | ||
| Suppression of steady-state, but not stimulus-induced NF-kappaB activity inhibits alphavirus-induced apoptosis | Q36256156 | ||
| The hepatitis B virus X gene induces p53-mediated programmed cell death | Q36303449 | ||
| The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks. | Q36642780 | ||
| The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors | Q36684890 | ||
| Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis | Q36830710 | ||
| Isolation and molecular characterization of hepatitis B virus X-protein from a baculovirus expression system | Q36885720 | ||
| Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway | Q38321449 | ||
| Cytosol is the prime compartment of hepatitis B virus X protein where it colocalizes with the proteasome | Q39466370 | ||
| Expression of mutated hepatitis B virus X genes in human hepatocellular carcinomas | Q39486033 | ||
| The human T-cell leukemia virus type I Tax protein induces apoptosis which is blocked by the Bcl-2 protein | Q40040736 | ||
| Induction of cell cycle progression by hepatitis B virus HBx gene expression in quiescent mouse fibroblasts | Q40345663 | ||
| X-gene product of hepatitis B virus induces apoptosis in liver cells | Q41067693 | ||
| Analysis of the tumorigenicity of the X gene of hepatitis B virus in a nontransformed hepatocyte cell line and the effects of cotransfection with a murine p53 mutant equivalent to human codon 249. | Q41155603 | ||
| Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. | Q41335848 | ||
| The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice | Q42651224 | ||
| Exogenous nucleosides promote the completion of MoMLV DNA synthesis in G0-arrested Balb c/3T3 fibroblasts | Q42800452 | ||
| Establishment and characterization of cell lines constitutively expressing hepatitis B virus X-protein | Q43443177 | ||
| Expression of hepatitis B virus X protein in HBV-infected human livers and hepatocellular carcinomas | Q43857388 | ||
| HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions | Q44489320 | ||
| The X gene of hepatitis B virus induced growth stimulation and tumorigenic transformation of mouse NIH3T3 cells | Q45166424 | ||
| Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma | Q45279592 | ||
| HBx protein of hepatitis B virus interacts with the C-terminal portion of a novel human proteasome alpha-subunit | Q45288557 | ||
| p53-independent apoptotic effects of the hepatitis B virus HBx protein in vivo and in vitro | Q45753041 | ||
| Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene | Q45770734 | ||
| Effect of hepatocyte proliferation and cellular DNA synthesis on hepatitis B virus replication | Q45771158 | ||
| HBx gene of hepatitis B virus induces liver cancer in transgenic mice | Q45852802 | ||
| A novel PCR technique using Alu-specific primers to identify unknown flanking sequences from the human genome | Q71150698 | ||
| Janus faces of NF-kappa B: neurodestruction versus neuroprotection | Q71952834 | ||
| Two-codon insertion mutations of the HBx define two separate regions necessary for its trans-activation function | Q72629154 | ||
| P433 | issue | 34 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Hepatitis B virus | Q6844 |
| hepatitis B | Q6853 | ||
| hepatocellular carcinoma | Q1148337 | ||
| P304 | page(s) | 4848-4859 | |
| P577 | publication date | 1999-08-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Hepatitis B virus X mutants, present in hepatocellular carcinoma tissue abrogate both the antiproliferative and transactivation effects of HBx. | |
| P478 | volume | 18 |
| Q37728191 | A mutant of HBx (HBxDelta127) promotes hepatoma cell growth via sterol regulatory element binding protein 1c involving 5-lipoxygenase |
| Q33622555 | A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase |
| Q36190691 | Aggregate formation of hepatitis B virus X protein affects cell cycle and apoptosis |
| Q38708561 | An efficient rapid system for assaying HBx-mediated transactivation |
| Q40077592 | Analysis of the complete hepatitis B virus genome in patients with genotype C chronic hepatitis and hepatocellular carcinoma |
| Q36249804 | Anti-hepatitis B virus (HBV) response of imiquimod based toll like receptor 7 ligand in hbv-positive human hepatocelluar carcinoma cell line |
| Q40394579 | Apoptosis and its pathway in X gene-transfected HepG2 cells |
| Q34248399 | Apoptosis in diseases of the liver |
| Q41913122 | Association between Hepatitis B Virus X Gene Mutations and Clinical Status in Patients with Chronic Hepatitis B Infection |
| Q36841560 | Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma |
| Q36190368 | Biological impacts of "hot-spot" mutations of hepatitis B virus X proteins are genotype B and C differentiated |
| Q39310264 | C-terminal truncated hepatitis B virus x protein is associated with metastasis and enhances invasiveness by C-Jun/matrix metalloproteinase protein 10 activation in hepatocellular carcinoma. |
| Q37220648 | COOH-terminal deletion of HBx gene is a frequent event in HBV-associated hepatocellular carcinoma |
| Q33988586 | Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development |
| Q30967003 | Characterisation of hepatitis B virus X protein mutants in tumour and non-tumour liver cells using laser capture microdissection. |
| Q53371976 | Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis. |
| Q36557635 | Chronic hepatitis B in hepatocarcinogenesis |
| Q42496260 | Clinical features and prognosis of hepatocellular carcinoma with respect to pre-S deletion and basal core promoter mutations of hepatitis B virus Genotype C2. |
| Q33801311 | Clinical implications of hepatitis B virus mutations: recent advances |
| Q82044308 | Combined pre‐S deletion and core promoter mutations related to hepatocellular carcinoma: A nested case‐control study in China |
| Q58811133 | Conserved transactivating and pro-apoptotic functions of hepadnaviral X protein in ortho- and avihepadnaviruses |
| Q34177169 | Cooperation of tumor-derived HBx mutants and p53-249(ser) mutant in regulating cell proliferation, anchorage-independent growth and aneuploidy in a telomerase-immortalized normal human hepatocyte-derived cell line |
| Q30837854 | Cytochrome C oxidase III interacts with hepatitis B virus X protein in vivo by yeast two-hybrid system |
| Q39218547 | Deep sequencing of the hepatitis B virus in hepatocellular carcinoma patients reveals enriched integration events, structural alterations and sequence variations |
| Q36122062 | Discovery of a Novel Mutation (X8Del) Resulting in an 8-bp Deletion in the Hepatitis B Virus X Gene Associated with Occult Infection in Korean Vaccinated Individuals |
| Q42615096 | Distinct mutant hepatitis B virus genomes, with alterations in all four open reading frames, in a single South African hepatocellular carcinoma patient. |
| Q44397705 | Dominant mutations of hepatitis B virus variants in hepatoma accumulate in B-cell and T-cell epitopes of the HBx antigen |
| Q42248914 | Effect of combined mutations in the enhancer II and basal core promoter of hepatitis B virus on development of hepatocellular carcinoma in Qidong, China |
| Q40007645 | Effects of hepatitis B virus X protein (HBx) on cell-growth inhibition in a CCL13-HBx stable cell line. |
| Q35073136 | European multicenter evaluation of high-density DNA probe arrays for detection of hepatitis B virus resistance mutations and identification of genotypes |
| Q45735690 | Expression of hepatitis B virus X protein is closely correlated with the high periportal inflammatory activity of liver diseases |
| Q47552769 | Extrahepatic cancers and chronic HCV infection |
| Q37189594 | Gene modulation associated with inhibition of liver regeneration in hepatitis B virus X transgenic mice |
| Q34611410 | Genetic mechanisms of hepatocarcinogenesis |
| Q52951327 | HBX causes cyclin D1 overexpression and development of breast cancer in transgenic animals that are heterozygous for p53. |
| Q24811785 | HBx M130K and V131I (T-A) mutations in HBV genotype F during a follow-up study in chronic carriers |
| Q37375282 | HBx mutations promote hepatoma cell migration through the Wnt/β-catenin signaling pathway |
| Q38840132 | HBx triggers either cellular senescence or cell proliferation depending on cellular phenotype |
| Q36956039 | Hepatitis B Virus-Encoded X Protein Downregulates EGFR Expression via Inducing MicroRNA-7 in Hepatocellular Carcinoma Cells |
| Q37776350 | Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC): Molecular mechanisms and novel paradigms |
| Q40907826 | Hepatitis B virus HBx protein activation of cyclin A-cyclin-dependent kinase 2 complexes and G1 transit via a Src kinase pathway |
| Q37885837 | Hepatitis B virus X gene and hepatocarcinogenesis. |
| Q45740490 | Hepatitis B virus X gene variability in French-born patients with chronic hepatitis and hepatocellular carcinoma |
| Q40794530 | Hepatitis B virus X mutants derived from human hepatocellular carcinoma retain the ability to abrogate p53-induced apoptosis |
| Q28216576 | Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2 |
| Q40760811 | Hepatitis B virus X protein differentially regulates cell cycle progression in X-transforming versus nontransforming hepatocyte (AML12) cell lines |
| Q39165248 | Hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis. |
| Q34742600 | Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1. |
| Q40658238 | Hepatitis B virus X protein induces cell death by causing loss of mitochondrial membrane potential |
| Q37621008 | Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis |
| Q36389447 | Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction |
| Q38110262 | Hepatitis B virus X protein-induced aberrant epigenetic modifications contributing to human hepatocellular carcinoma pathogenesis |
| Q34308890 | Hepatitis B virus and hepatocellular carcinoma |
| Q34052514 | Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients |
| Q36795324 | Hepatitis B virus genetic variants: biological properties and clinical implications |
| Q27024874 | Hepatitis B virus, HBx mutants and their role in hepatocellular carcinoma |
| Q36519025 | Hepatitis B virus-related hepatocellular carcinoma: paradigms for viral-related human carcinogenesis |
| Q45741819 | Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis |
| Q34398029 | Hepatitis viruses and hepatocarcinogenesis |
| Q35882733 | Hepatocellular carcinoma: role of hepatitis B and hepatitis C viruses proteins in hepatocarcinogenesis |
| Q37888329 | Hepatocellular carcinoma: the point of view of the hepatitis B virus |
| Q34717373 | Hepatoma cell line HepG2.2.15 demonstrates distinct biological features compared with parental HepG2. |
| Q92757305 | High possibility of hepatocarcinogenesis in HBV genotype C1 infected Cambodians is indicated by 340 HBV C1 full-genomes analysis from GenBank |
| Q39999789 | Identification of a natural mutant of HBV X protein truncated 27 amino acids at the COOH terminal and its effect on liver cell proliferation |
| Q45404616 | Impact of hepatitis B virus basic core promoter mutations on T cell response to an immunodominant HBx-derived epitope |
| Q36006754 | Impact of transforming viruses on cellular mutagenesis, genome stability, and cellular transformation |
| Q40894487 | Induction of apoptosis by the transactivating domains of the hepatitis B virus X gene leads to suppression of oncogenic transformation of primary rat embryo fibroblasts |
| Q36098721 | Influence of hepatitis B virus X and core promoter mutations on hepatocellular carcinoma among patients infected with subgenotype C2. |
| Q24555051 | Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver |
| Q34082379 | Interaction of Hepatitis B virus with cellular processes in liver carcinogenesis |
| Q39570667 | Interaction of mutant hepatitis B X protein with p53 tumor suppressor protein affects both transcription and cell survival |
| Q45273532 | Low frequency of mutations in the X gene, core promoter and precore region of hepatitis B virus infected Vietnamese |
| Q36226733 | Mitochondria as functional targets of proteins coded by human tumor viruses |
| Q36066290 | Modulation of apoptosis as a target for liver disease |
| Q33855801 | Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma |
| Q35541482 | Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview |
| Q45361333 | Mutational complex genotype of the hepatitis B virus X /precore regions as a novel predictive marker for hepatocellular carcinoma |
| Q36743649 | Mutations in the C-terminus of the X protein of hepatitis B virus regulate Wnt-5a expression in hepatoma Huh7 cells: cDNA microarray and proteomic analyses |
| Q44053478 | NF-kappaB activation by hepatitis B virus X (HBx) protein shifts the cellular fate toward survival. |
| Q34068117 | Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesis |
| Q104570091 | Partial abrogation of FXR-KNG1 signaling by carboxyl-terminal truncated HBx-C30 in hepatitis B virus-associated hepatocellular carcinoma |
| Q45879104 | Potential oncogene activity of the woodchuck hepatitis post-transcriptional regulatory element (WPRE). |
| Q37093046 | Prospective evaluation of hepatitis B 1762(T)/1764(A) mutations on hepatocellular carcinoma development in Shanghai, China |
| Q37285249 | Quasispecies structure, cornerstone of hepatitis B virus infection: mass sequencing approach |
| Q38517215 | Reduced expression of epidermal growth factor receptor-related protein in hepatocellular carcinoma: implications for cancer growth |
| Q34389406 | Retracted: The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation |
| Q33834716 | Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein |
| Q56972496 | Roles of p53 in extrinsic factor-induced liver carcinogenesis |
| Q33661054 | Significance of viral status on occurrence of hepatitis B-related hepatocellular carcinoma |
| Q92034895 | Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction |
| Q35078725 | TP53 and liver carcinogenesis. |
| Q36777331 | TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer |
| Q38056849 | Tackling hepatitis B virus-associated hepatocellular carcinoma--the future is now. |
| Q35060821 | Technical standards for hepatitis B virus X protein (HBx) research |
| Q39640953 | The C-terminal region of the hepatitis B virus X protein is essential for its stability and function |
| Q44449821 | The C-terminal region of the hepatitis B virus X protein is required for its stimulation of HBV replication in primary mouse hepatocytes |
| Q45855338 | The CD20/alphaCD20 'suicide' system: novel vectors with improved safety and expression profiles and efficient elimination of CD20-transgenic T cells |
| Q24561887 | The enigmatic X gene of hepatitis B virus |
| Q40796694 | The hepatitis B virus HBx protein induces adherens junction disruption in a src-dependent manner. |
| Q45733889 | The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver |
| Q34438821 | The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage |
| Q36419017 | The molecular diagnosis of hepatitis B virus-associated hepatocellular carcinoma. |
| Q28288613 | The role of the hepatitis viruses in cholangiocarcinoma |
| Q33200560 | Transfection and expression of hepatitis B virus x gene and its effect on apoptosis in HL-7702 cells |
| Q41272310 | Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis. |
| Q34781813 | Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB. |
| Q34308946 | Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes |
| Q37260746 | USP16 Downregulation by Carboxyl-terminal Truncated HBx Promotes the Growth of Hepatocellular Carcinoma Cells |
| Q36433765 | Update of research and management of hepatitis B. |
| Q38408911 | Variations and mutations in the hepatitis B virus genome and their associations with clinical characteristics |
| Q34737124 | Viral determinants and host immune responses in the pathogenesis of HBV infection. |
| Q42525426 | Virological and clinical implication of core promoter C1752/V1753 and T1764/G1766 mutations in hepatitis B virus genotype D infection in Mongolia |
| Q24653900 | Viruses associated with human cancer |
| Q38643087 | Wild type HBx and truncated HBx: Pleiotropic regulators driving sequential genetic and epigenetic steps of hepatocarcinogenesis and progression of HBV-associated neoplasms |
| Q40839488 | X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway |
| Q34234112 | X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis |
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