Structural analysis of SepL, an enteropathogenic Escherichia coli type III secretion-system gatekeeper protein

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Structural analysis of SepL, an enteropathogenic Escherichia coli type III secretion-system gatekeeper protein is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1107/S2053230X15016064
P932PMC publication ID4601595
P698PubMed publication ID26457522

P2093author name stringNatalie C J Strynadka
Brianne J Burkinshaw
Sergio A Souza
P2860cites workXtalPred: a web server for prediction of protein crystallizabilityQ56978525
A computer-linked cathode-ray tube microdensitometer for X-ray crystallographyQ71156753
Restriction site-free insertion of PCR products directionally into vectorsQ73562838
MxiC is secreted by and controls the substrate specificity of the Shigella flexneri type III secretion apparatusQ82645592
Structural insights into the assembly of the type III secretion needle complex.Q24547949
MolProbity: all-atom structure validation for macromolecular crystallographyQ24649111
Bioinformatics analysis of the locus for enterocyte effacement provides novel insights into type-III secretionQ24791468
Structures of the Shigella flexneri Type 3 Secretion System Protein MxiC Reveal Conformational Variability Amongst HomologuesQ27649946
Structural analysis of the essential self-cleaving type III secretion proteins EscU and SpaSQ27650496
Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniaeQ27684803
Automated structure solution with autoSHARPQ27860516
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
Overview of the CCP4 suite and current developmentsQ27860782
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Phasercrystallographic softwareQ27860930
Features and development of CootQ27861079
Salmonella type III secretion-associated protein InvE controls translocation of effector proteins into host cellsQ34317570
Subversion of trafficking, apoptosis, and innate immunity by type III secretion system effectorsQ34358655
Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis.Q34392473
The needle length of bacterial injectisomes is determined by a molecular ruler.Q34543727
The Chlamydia effector chlamydial outer protein N (CopN) sequesters tubulin and prevents microtubule assemblyQ35310949
A gatekeeper chaperone complex directs translocator secretion during type three secretionQ35398859
EscE and EscG are cochaperones for the type III needle protein EscF of enteropathogenic Escherichia coliQ36911591
Decision making in xia2.Q36946740
Structure and biophysics of type III secretion in bacteriaQ37014297
Dissecting virulence: systematic and functional analyses of a pathogenicity islandQ37074383
Structural overview of the bacterial injectisomeQ37812889
Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism.Q37875136
Assembly of the bacterial type III secretion machinery.Q38183945
Bacterial injectisomes: needle length does matter.Q40454286
Interplay between predicted inner-rod and gatekeeper in controlling substrate specificity of the type III secretion systemQ41402188
Selection and characterization of Yersinia pestis YopN mutants that constitutively block Yop secretion.Q41457355
Translocation of YopE and YopN into eukaryotic cells by Yersinia pestis yopN, tyeA, sycN, yscB and lcrG deletion mutants measured using a phosphorylatable peptide tag and phosphospecific antibodiesQ41469138
Shigella IpaD has a dual role: signal transduction from the type III secretion system needle tip and intracellular secretion regulation.Q42128393
The Shigella T3SS needle transmits a signal for MxiC release, which controls secretion of effectorsQ42168584
SepL resembles an aberrant effector in binding to a class 1 type III secretion chaperone and carrying an N-terminal secretion signalQ42375349
Regulation of type III secretion hierarchy of translocators and effectors in attaching and effacing bacterial pathogensQ42727344
A new method for protein coexpression in Escherichia coli using two incompatible plasmidsQ43693978
Hierarchal type III secretion of translocators and effectors from Escherichia coli O157:H7 requires the carboxy terminus of SepL that binds to Tir.Q46450220
SepL, a protein required for enteropathogenic Escherichia coli type III translocation, interacts with secretion component SepD.Q47373545
P433issuePt 10
P921main subjectEscherichia coliQ25419
Enteropathogenic Escherichia coliQ13419512
enteropathogenQ63500873
P304page(s)1300-1308
P577publication date2015-09-23
P1433published inActa crystallographica. Section F, Structural biology communicationsQ27725274
P1476titleStructural analysis of SepL, an enteropathogenic Escherichia coli type III secretion-system gatekeeper protein
P478volume71

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cites work (P2860)
Q47434181Hierarchical protein targeting and secretion is controlled by an affinity switch in the type III secretion system of enteropathogenic Escherichia coli.
Q90170341On the road to structure-based development of anti-virulence therapeutics targeting the type III secretion system injectisome
Q40166358Regulation of Type III Secretion of Translocon and Effector Proteins by the EsaB/EsaL/EsaM Complex in Edwardsiella tarda.
Q42324204Steps for Shigella Gatekeeper Protein MxiC Function in Hierarchical Type III Secretion Regulation.
Q28074332Type Three Secretion System in Attaching and Effacing Pathogens

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