Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts

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Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1015857953
P356DOI10.1038/SJ.ONC.1208564
P698PubMed publication ID15782119
P5875ResearchGate publication ID7953230

P50authorNaoki YamamotoQ86902511
P2093author name stringShoji Yamaoka
Toshiki Watanabe
Ryouichi Horie
Mizuho Nonaka
Kinji Itoh
P2860cites workTRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathwaysQ24317441
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2Q27639845
MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survivalQ28190315
NF-kappaB regulation in the immune systemQ28205043
Pleiotropic signal transduction mediated by human CD30: a member of the tumor necrosis factor receptor (TNFR) familyQ28208696
Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activityQ28383134
Two carboxyl-terminal activation regions of Epstein-Barr virus latent membrane protein 1 activate NF-kappaB through distinct signaling pathways in fibroblast cell linesQ28565703
Shaping the nuclear action of NF-kappaBQ29614600
Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activationQ29617419
TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.Q31148506
OX40 stimulation by gp34/OX40 ligand enhances productive human immunodeficiency virus type 1 infectionQ33844046
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.Q33863064
Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.Q34112913
Lymphotoxin beta receptor induces sequential activation of distinct NF-kappa B factors via separate signaling pathwaysQ34173731
Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cellsQ34274124
Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.Q34520814
Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis.Q34532538
The role of cytokines in classical Hodgkin lymphomaQ34661066
Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activityQ36107713
The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesisQ36371653
Regulation of NF-kappaB activity by I kappaB-related proteins in adenocarcinoma cellsQ38324140
Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profilingQ39741184
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cellsQ39795545
Tax-independent constitutive IkappaB kinase activation in adult T-cell leukemia cellsQ40553944
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradationQ40566781
Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathwayQ40623366
Latent membrane protein 1 of Epstein-Barr virus stimulates processing of NF-kappa B2 p100 to p52.Q40628193
Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphomaQ40679662
The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathwaysQ40696432
Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cellsQ40736248
RelB cellular regulation and transcriptional activity are regulated by p100.Q40771390
Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines.Q40772885
Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.Q40972388
GM-CSF-induced in vivo expansion of splenic dendritic cells and their strong costimulation activityQ41180118
The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-kappaB activation in anaplastic large cell lymphomaQ44848855
RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor ActivationQ57093168
Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3Q73540287
Of mice and menQ80243690
P433issue24
P407language of work or nameEnglishQ1860
P304page(s)3976-3986
P577publication date2005-06-01
P1433published inOncogeneQ1568657
P1476titleAberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts
P478volume24

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cites work (P2860)
Q36254865Activation of NF-kappaB by HTLV-I and implications for cell transformation
Q58698930Analysis of NF-κB Pathway Proteins in Pediatric Hodgkin Lymphoma: Correlations with EBV Status and Clinical Outcome—A Children's Oncology Group Study
Q40177590CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells
Q40026531CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells
Q40183372Efficient induction of HIV-1 replication in latently infected cells through contact with CD4+ T cells: involvement of NF-kappaB activation
Q36370847Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival
Q40383844Hodgkin's lymphoma cells are efficiently engrafted and tumor marker CD30 is expressed with constitutive nuclear factor-kappaB activity in unconditioned NOD/SCID/gammac(null) mice
Q34707404Hypomethylation of CD30 CpG islands with aberrant JunB expression drives CD30 induction in Hodgkin lymphoma and anaplastic large cell lymphoma
Q38182355Mechanisms and consequences of constitutive NF-κB activation in B-cell lymphoid malignancies
Q54147337NF-κB in Hematological Malignancies.
Q38178074NF-κB pathways in hematological malignancies
Q38988815NF-κB signaling pathway and its potential as a target for therapy in lymphoid neoplasms
Q37822660Non-canonical NF-κB signaling pathway
Q39468269Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells
Q34624443Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation
Q35125212TRAF2 recruitment via T61 in CD30 drives NFκB activation and enhances hESC survival and proliferation
Q50443743The NFKB Inducing Kinase Modulates Hematopoiesis During Stress
Q39350735The non-canonical NF-κB pathway in immunity and inflammation
Q40347662cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3.
Q36961217hESC adaptation, selection and stability

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