Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival

scientific article

Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2012-01-405951
P932PMC publication ID3488888
P698PubMed publication ID22968463
P5875ResearchGate publication ID230832944

P50authorElaine JaffeQ19647268
Stefania PittalugaQ87358458
Moses O EvbuomwanQ114721616
P2093author name stringBrian A Lewis
Stella M Ranuncolo
P2860cites workChronic active B-cell-receptor signalling in diffuse large B-cell lymphomaQ24613755
Autophagy and NF-kappaB: fight for fateQ24658157
Distinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
Oncogenically active MYD88 mutations in human lymphomaQ28301648
Rescue of TRAF3-null mice by p100 NF-kappa B deficiencyQ28506895
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cellsQ29547557
Regulation and function of NF-kappaB transcription factors in the immune systemQ29616427
A loss-of-function RNA interference screen for molecular targets in cancerQ33237976
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphomaQ33432504
The regulatory logic of the NF-kappaB signaling systemQ33685419
Selectivity of the NF-{kappa}B responseQ33752186
Roles of the NF-kappaB pathway in lymphocyte development and functionQ33800318
Oncogenic activation of NF-kappaB.Q33849388
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha.Q33863064
Negative feedback in noncanonical NF-kappaB signaling modulates NIK stability through IKKalpha-mediated phosphorylationQ34034515
Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma.Q34112913
Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cellsQ34274124
Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells.Q34505714
Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.Q34520814
Histopathology of Hodgkin's lymphomaQ34977540
Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of developmentQ35888216
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.Q36155317
Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organsQ36156167
Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphomaQ36375732
Lymphoid organ development: from ontogeny to neogenesisQ36426808
Contribution of the Epstein Barr virus to the molecular pathogenesis of Hodgkin lymphoma.Q37016499
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myelomaQ37314736
The biology of Hodgkin's lymphomaQ37349652
Pathogenesis of classical and lymphocyte-predominant Hodgkin lymphomaQ37463052
The NF-kappaB family of transcription factors and its regulationQ37672294
Non-canonical NF-κB signaling pathwayQ37822660
TRAF2 and TRAF3 signal adapters act cooperatively to control the maturation and survival signals delivered to B cells by the BAFF receptor.Q38293065
Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphomaQ39370671
Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcomeQ39722611
Oncogenic CARD11 mutations in human diffuse large B cell lymphomaQ40005246
Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblastsQ40443980
Regulation of NF-kappa B2 p100 processing by its cis-acting domainQ40504235
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradationQ40566781
Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphomaQ40679662
Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient.Q41206007
NF-kappaB inducing kinase (NIK) inhibitors: identification of new scaffolds using virtual screening.Q43004622
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signalingQ43142702
Stabilization of basally translated NF-kappaB-inducing kinase (NIK) protein functions as a molecular switch of processing of NF-kappaB2 p100.Q46751773
EBV positive mucocutaneous ulcer--a study of 26 cases associated with various sources of immunosuppression.Q54441409
High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cellsQ71099795
Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cellsQ80786111
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectHodgkin lymphomaQ209369
P304page(s)3756-3763
P577publication date2012-09-11
P1433published inBloodQ885070
P1476titleHodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival
P478volume120

Reverse relations

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