| scholarly article | Q13442814 |
| P50 | author | Paul G Murray | Q92665882 |
| Martina Vockerodt | Q112373862 | ||
| P2093 | author name string | Wenbin Wei | |
| Eszter Nagy | |||
| Tracey Perry | |||
| Ciaran Woodman | |||
| Maha Ibrahim | |||
| Katerina Vrzalikova | |||
| P2860 | cites work | Epstein-Barr virus LMP2A-induced B-cell survival in two unique classes of EmuLMP2A transgenic mice | Q24524255 |
| Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL | Q24681342 | ||
| Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma. | Q45401541 | ||
| Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas | Q45424270 | ||
| Epstein-Barr virus infection in vitro can rescue germinal center B cells with inactivated immunoglobulin genes | Q45424361 | ||
| Lymphoma resembling Hodgkin disease after posttransplant lymphoproliferative disorder in a liver transplant recipient | Q70487156 | ||
| High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells | Q71099795 | ||
| Increased incidence of Hodgkin's disease after allogeneic bone marrow transplantation | Q73042220 | ||
| Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells | Q73453075 | ||
| The role of eosinophils in the pathobiology of Hodgkin's disease | Q73481560 | ||
| Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma | Q77461381 | ||
| Epstein-Barr Virus (EBV) LMP2A induces alterations in gene transcription similar to those observed in Reed-Sternberg cells of Hodgkin lymphoma | Q45722302 | ||
| Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses | Q45746898 | ||
| Monoclonal antibodies directed against the Epstein-Barr virus-encoded nuclear antigen 1 (EBNA1): immunohistologic detection of EBNA1 in the malignant cells of Hodgkin's disease | Q45782539 | ||
| Persistence of Epstein-Barr virus in Reed-Sternberg cells throughout the course of Hodgkin's disease. | Q45790084 | ||
| The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B | Q45876441 | ||
| STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis | Q46506090 | ||
| EBV persistence in memory B cells in vivo. | Q52037383 | ||
| Demonstration of monoclonal EBV genomes in Hodgkin's disease and Ki-1-positive anaplastic large cell lymphoma by combined Southern blot and in situ hybridization. | Q53038037 | ||
| Loss of B cell identity correlates with loss of B cell-specific transcription factors in Hodgkin/Reed-Sternberg cells of classical Hodgkin lymphoma. | Q53388471 | ||
| An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells. | Q53541156 | ||
| LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1 | Q57198201 | ||
| Hodgkin's disease: clonal Ig gene rearrangements in Hodgkin and Reed-Sternberg cells picked from histological sections | Q57198369 | ||
| Expression of the Cytoplasmic Tail of LMP1 in Mice Induces Hyperactivation of B Lymphocytes and Disordered Lymphoid Architecture | Q57791640 | ||
| Human CD30+ B cells represent a unique subset related to Hodgkin lymphoma cells. | Q64917080 | ||
| Detection of Epstein-Barr viral genomes in Reed-Sternberg cells of Hodgkin's disease | Q69328485 | ||
| Epstein-Barr virus LMP2A reduces hyperactivation induced by LMP1 to restore normal B cell phenotype in transgenic mice | Q27345929 | ||
| Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
| Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists | Q28131785 | ||
| Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activity | Q28383134 | ||
| Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation | Q33236181 | ||
| TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma | Q33432504 | ||
| Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A. | Q33754907 | ||
| Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha. | Q33863064 | ||
| Epstein-Barr virus latent membrane protein-1 triggers AP-1 activity via the c-Jun N-terminal kinase cascade | Q33887684 | ||
| Epstein-Barr virus-mediated B-cell proliferation is dependent upon latent membrane protein 1, which simulates an activated CD40 receptor | Q33888498 | ||
| Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins | Q33891012 | ||
| Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma. | Q34112913 | ||
| Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule. | Q34250209 | ||
| Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells | Q34274124 | ||
| Gene expression profiling of microdissected Hodgkin Reed-Sternberg cells correlates with treatment outcome in classical Hodgkin lymphoma | Q34407534 | ||
| Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma | Q34480682 | ||
| Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells. | Q34505714 | ||
| Loss of the B-lineage-specific gene expression program in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma | Q34528341 | ||
| Terminal differentiation into plasma cells initiates the replicative cycle of Epstein-Barr virus in vivo | Q34553645 | ||
| The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function | Q34577080 | ||
| Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas. | Q34627655 | ||
| Suppression of the LMP2A target gene, EGR-1, protects Hodgkin's lymphoma cells from entry to the EBV lytic cycle. | Q34650591 | ||
| Down-regulation of the TGF-beta target gene, PTPRK, by the Epstein-Barr virus encoded EBNA1 contributes to the growth and survival of Hodgkin lymphoma cells. | Q34667546 | ||
| Epstein-Barr virus LMP2A enhances B-cell responses in vivo and in vitro | Q34717880 | ||
| Recurrent somatic mutations of PTPN1 in primary mediastinal B cell lymphoma and Hodgkin lymphoma | Q35095028 | ||
| LMP1-deficient Epstein-Barr virus mutant requires T cells for lymphomagenesis | Q35242466 | ||
| Aberrant expression of ID2, a suppressor of B-cell-specific gene expression, in Hodgkin's lymphoma | Q35607200 | ||
| An EBNA-1-dependent enhancer acts from a distance of 10 kilobase pairs to increase expression of the Epstein-Barr virus LMP gene | Q35838226 | ||
| Rescue of "crippled" germinal center B cells from apoptosis by Epstein-Barr virus | Q35848189 | ||
| Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development | Q35888216 | ||
| Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model. | Q35943724 | ||
| Mapping genetic elements of Epstein-Barr virus that facilitate extrachromosomal persistence of Epstein-Barr virus-derived plasmids in human cells | Q40666871 | ||
| Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma | Q40679662 | ||
| Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells | Q40736248 | ||
| The Epstein-Barr virus encoded latent membrane protein 2A augments signaling from latent membrane protein 1. | Q40771232 | ||
| Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines. | Q40772885 | ||
| The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell | Q40843575 | ||
| Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1). | Q41044165 | ||
| Hodgkin's disease following solid organ transplantation | Q41064028 | ||
| Single cell analysis of Hodgkin/Reed-Sternberg cells | Q41135528 | ||
| In vivo growth of Epstein-Barr virus transformed B cells with mutations in latent membrane protein 2 (LMP2). | Q41139567 | ||
| Expression of the Epstein Barr virus transforming protein LMP1 causes a rapid and transient stimulation of the Bcl-2 homologue Mcl-1 levels in B-cell lines. | Q41158830 | ||
| The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain. | Q41371042 | ||
| Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines | Q41378283 | ||
| Expression of bcl-2 in Burkitt's lymphoma cell lines: induction by latent Epstein-Barr virus genes | Q41613780 | ||
| Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death | Q41678654 | ||
| CD40 ligand is constitutively expressed in a subset of T cell lymphomas and on the microenvironmental reactive T cells of follicular lymphomas and Hodgkin's disease. | Q41920906 | ||
| CD80 (B7.1) and CD86 (B7.2) induce EBV-transformed B cell apoptosis through the Fas/FasL pathway | Q42271908 | ||
| CD40-induced growth inhibition in epithelial cells is mimicked by Epstein-Barr Virus-encoded LMP1: involvement of TRAF3 as a common mediator. | Q42527769 | ||
| Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model | Q42564555 | ||
| Epstein-Barr virus-associated lymphoproliferative disease in non-immunocompromised hosts: a status report and summary of an international meeting, 8-9 September 2008. | Q43065304 | ||
| STAT3 is constitutively activated in Hodgkin cell lines | Q43684719 | ||
| The Epstein-Barr virus oncoprotein, latent membrane protein-1, reprograms germinal centre B cells towards a Hodgkin's Reed-Sternberg-like phenotype. | Q43808409 | ||
| Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals | Q44664210 | ||
| Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway | Q35948025 | ||
| Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A. | Q36079038 | ||
| Epstein-Barr virus latent membrane protein 2A is a B-cell receptor mimic and essential for B-cell survival | Q36141691 | ||
| Transcriptome changes induced by Epstein-Barr virus LMP1 and LMP2A in transgenic lymphocytes and lymphoma. | Q36250603 | ||
| Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice | Q36327458 | ||
| Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. | Q36367466 | ||
| Hodgkin lymphoma requires stabilized NIK and constitutive RelB expression for survival | Q36370847 | ||
| Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma | Q36375732 | ||
| EBV LMP2A affects LMP1-mediated NF-kappaB signaling and survival of lymphoma cells by regulating TRAF2 expression | Q36508964 | ||
| South Asian ethnicity and material deprivation increase the risk of Epstein-Barr virus infection in childhood Hodgkin's disease | Q36623552 | ||
| Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes | Q36646940 | ||
| The only domain which distinguishes Epstein-Barr virus latent membrane protein 2A (LMP2A) from LMP2B is dispensable for lymphocyte infection and growth transformation in vitro; LMP2A is therefore nonessential | Q36685081 | ||
| Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis | Q36699754 | ||
| A promoter of Epstein-Barr virus that can function during latent infection can be transactivated by EBNA-1, a viral protein required for viral DNA replication during latent infection. | Q36828303 | ||
| Multiple EBNA1-binding sites are required to form an EBNA1-dependent enhancer and to activate a minimal replicative origin within oriP of Epstein-Barr virus. | Q36828339 | ||
| Epstein-Barr virus-associated Hodgkin's disease: epidemiologic characteristics in international data. | Q36846594 | ||
| trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1. | Q36899288 | ||
| Mouse model for acute Epstein-Barr virus infection | Q37473875 | ||
| Epstein-Barr virus and Hodgkin's disease: transcriptional analysis of virus latency in the malignant cells | Q38322174 | ||
| High prevalence of Epstein-Barr virus in the Reed-Sternberg cells of Hodgkin's disease occurring in Peru | Q38322415 | ||
| Mutations of NFKBIA, encoding IkappaB alpha, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases | Q38353369 | ||
| The consistent association between Epstein-Barr virus and Hodgkin's disease in children in Kenya. | Q38478229 | ||
| Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. | Q38486378 | ||
| Immunohistochemical demonstration of the Epstein-Barr virus-encoded latent membrane protein in paraffin sections of Hodgkin's disease | Q38488345 | ||
| Role of early B-cell factor 1 (EBF1) in Hodgkin lymphoma | Q39240522 | ||
| Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma | Q39284003 | ||
| Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma | Q39370671 | ||
| Genome-wide copy number analysis of Hodgkin Reed-Sternberg cells identifies recurrent imbalances with correlations to treatment outcome | Q39722611 | ||
| Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling | Q39741184 | ||
| Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells | Q39795545 | ||
| Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes | Q40048949 | ||
| Epstein-Barr virus-encoded EBNA1 regulates cellular gene transcription and modulates the STAT1 and TGFbeta signaling pathways | Q40135893 | ||
| Deletion of the nontransforming Epstein-Barr virus strain P3HR-1 causes fusion of the large internal repeat to the DSL region | Q40142296 | ||
| Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease | Q40269570 | ||
| Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma | Q40337542 | ||
| Latent Membrane Protein 1 (LMP1) and LMP2A Collaborate To Promote Epstein-Barr Virus-Induced B Cell Lymphomas in a Cord Blood-Humanized Mouse Model but Are Not Essential. | Q40375799 | ||
| Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR. | Q40457592 | ||
| Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression | Q40530253 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Hodgkin lymphoma | Q209369 |
| membrane protein | Q423042 | ||
| cancer research | Q3421914 | ||
| Epstein–Barr virus | Q6900 | ||
| P304 | page(s) | 285 | |
| P577 | publication date | 2018-08-24 | |
| P1433 | published in | Cancers | Q27722963 |
| P1476 | title | Co-Expression of the Epstein-Barr Virus-Encoded Latent Membrane Proteins and the Pathogenesis of Classic Hodgkin Lymphoma | |
| P478 | volume | 10 |
| Q92814516 | Differences in Epstein-Barr Virus Characteristics and Viral-Related Microenvironment Could Be Responsible for Lymphomagenesis in Children |
| Q92986280 | Epstein-Barr virus infection is associated with clinical characteristics and poor prognosis of multiple myeloma |
| Q99580594 | Indolent T cell lymphoproliferative disorder of the gastrointestinal tract: an uncommon case with lymph node involvement and the classic Hodgkin's lymphoma |
| Q92860015 | The Global Landscape of EBV-Associated Tumors |
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