Zalcitabine. Clinical pharmacokinetics and efficacy.

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Zalcitabine. Clinical pharmacokinetics and efficacy. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1044500511
P356DOI10.2165/00003088-199528050-00002
P698PubMed publication ID7614775

P2093author name stringJ M Gallo
D Devineni
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Mitochondrial DNA replication does not involve DNA polymerase alphaQ71524088
Zalcitabine compared with zidovudine in patients with advanced HIV-1 infection who received previous zidovudine therapyQ72216009
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Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicityQ28327130
Human immunodeficiency virus inhibition is prolonged by 3'-azido-3'-deoxythymidine alternating with 2',3'-dideoxycytidine compared with 3'-azido-3'-deoxythymidine aloneQ28342825
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Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitroQ28361577
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Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiencyQ34055177
Nucleosides. IX. The Formation of 2',3'-Unsaturated Pyrimidine Nucleosides via a Novel β-Elimination Reaction1,2Q34241399
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Disseminated Kaposi's sarcoma in homosexual men.Q34253447
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Long-term inhibition of human T-lymphotropic virus type III/lymphadenopathy-associated virus (human immunodeficiency virus) DNA synthesis and RNA expression in T cells protected by 2',3'-dideoxynucleosides in vitroQ34610200
Zidovudine intolerance.Q37947318
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ZalcitabineQ40709556
Circulating p24 antigen levels and responses to dideoxycytidine in human immunodeficiency virus (HIV) infections. A phase I and II studyQ40778496
Severe Acquired Immunodeficiency in Male Homosexuals, Manifested by Chronic Perianal Ulcerative Herpes Simplex LesionsQ40849251
The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell speciesQ42200271
Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1.Q42200603
Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex.Q42284384
Genetic analysis of 2',3'-dideoxycytidine incorporation into cultured human T lymphoblastsQ42817658
Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infectionQ43514070
Restricted transport of 3'-azido-3'-deoxythymidine and dideoxynucleosides through the blood-brain barrierQ43805805
In vitro toxicity and metabolism of 2',3'-dideoxycytidine, an inhibitor of human immunodeficiency virus infectivityQ44079869
A pilot study of the bioavailability and pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS or AIDS-related complexQ44250538
Pharmacokinetic evaluation of drug interactions with anti-human immunodeficiency virus drugs. V. Effect of soluble CD4 on 2',3'-dideoxycytidine kinetics in monkeysQ44696573
P433issue5
P921main subjectpharmacokineticsQ323936
P304page(s)351-360
P577publication date1995-05-01
P1433published inClinical PharmacokineticsQ5133788
P1476titleZalcitabine. Clinical pharmacokinetics and efficacy.
P478volume28

Reverse relations

cites work (P2860)
Q30887008A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.
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Q41066477Drug interactions with antiviral drugs
Q36239813Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence?
Q33933495P-glycoprotein, secretory transport, and other barriers to the oral delivery of anti-HIV drugs
Q39558483Pharmacokinetics and distribution over the blood-brain barrier of zalcitabine (2',3'-dideoxycytidine) and BEA005 (2', 3'-dideoxy-3'-hydroxymethylcytidine) in rats, studied by microdialysis
Q84534725Renal excretion of apricitabine in rats: ex vivo and in vivo studies
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Q36130623Use of highly active antiretroviral therapy in patients with renal insufficiency
Q36851934Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions
Q41494492Zalcitabine. An update of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of HIV infection

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