| scholarly article | Q13442814 |
| P50 | author | Bing-Hua Jiang | Q63561312 |
| P2093 | author name string | Chang Xia | |
| Eddie Reed | |||
| Jing Fang | |||
| Jenny Z Zheng | |||
| Zongxian Cao | |||
| P2860 | cites work | The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis | Q22009936 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 342-353 | |
| P577 | publication date | 2005-03-01 | |
| P1433 | published in | FASEB Journal | Q520194 |
| P1476 | title | Apigenin inhibits VEGF and HIF-1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways. | |
| P478 | volume | 19 |
| Q35574943 | Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway |
| Q34150587 | Akt pathway is hypoactivated by synergistic actions of diabetes mellitus and hypercholesterolemia resulting in advanced coronary artery disease |
| Q24676614 | Akt1 in endothelial cell and angiogenesis |
| Q37077910 | Antiangiogenic activity and pharmacogenomics of medicinal plants from traditional korean medicine. |
| Q38512046 | Anticancer potential of the histone deacetylase inhibitor-like effects of flavones, a subclass of polyphenolic compounds: a review |
| Q53254694 | Apigenin Attenuates Melanoma Cell Migration by Inducing Anoikis through Integrin and Focal Adhesion Kinase Inhibition. |
| Q90399940 | Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis |
| Q33632438 | Apigenin in combination with Akt inhibition significantly enhances thyrotropin-stimulated radioiodide accumulation in thyroid cells |
| Q39645665 | Apigenin induces apoptosis in human lung cancer H460 cells through caspase- and mitochondria-dependent pathways |
| Q36920085 | Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms |
| Q24336102 | Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90 |
| Q38354037 | Apigenin inhibits proliferation of ovarian cancer A2780 cells through Id1. |
| Q54490286 | Apigenin inhibits the TNFα-induced expression of eNOS and MMP-9 via modulating Akt signalling through oestrogen receptor engagement. |
| Q47103763 | Apigenin sensitizes BEL-7402/ADM cells to doxorubicin through inhibiting miR-101/Nrf2 pathway |
| Q42001138 | Apigenin suppresses insulin-like growth factor I receptor signaling in human prostate cancer: an in vitro and in vivo study |
| Q42512359 | Apigenin-induced nitric oxide production involves calcium-activated potassium channels and is responsible for antiangiogenic effects |
| Q40002243 | Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation |
| Q28277257 | Apigenin: a promising molecule for cancer prevention |
| Q39431398 | Atorvastatin reduces vascular endothelial growth factor (VEGF) expression in human non-small cell lung carcinomas (NSCLCs) via inhibition of reactive oxygen species (ROS) production |
| Q36767664 | Autophagy inhibition enhances apigenin-induced apoptosis in human breast cancer cells |
| Q28247535 | Biotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2 |
| Q35793163 | Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones |
| Q34957306 | Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1 |
| Q39077231 | Chemotherapy-mediated p53-dependent DNA damage response in clear cell renal cell carcinoma: role of the mTORC1/2 and hypoxia-inducible factor pathways |
| Q39715971 | Cinnamon extract reduces VEGF expression via suppressing HIF-1α gene expression and inhibits tumor growth in mice |
| Q33634969 | Development of a Novel Anti-HIF-1α Screening System Coupled with Biochemical and Biological Validation for Rapidly Selecting Potent Anti-Cancer Compounds |
| Q37855700 | Dietary flavonoids as cancer prevention agents |
| Q64236351 | Enhanced Solubility and Bioavailability of Apigenin via Preparation of Solid Dispersions of Mesoporous Silica Nanoparticles |
| Q39544711 | Enhanced antitumor efficacy by blocking activation of the phosphatidylinositol 3-kinase/Akt pathway during anti-angiogenesis therapy |
| Q37022184 | Epithelial to mesenchymal transition in arsenic-transformed cells promotes angiogenesis through activating β-catenin-vascular endothelial growth factor pathway. |
| Q39492488 | Evaluation of selected flavonoids as antiangiogenic, anticancer, and radical scavenging agents: an experimental and in silico analysis |
| Q38007998 | Exploiting p70 S6 kinase as a target for ovarian cancer |
| Q42183550 | Forkhead transcription factor FOXO3a protein activates nuclear factor κB through B-cell lymphoma/leukemia 10 (BCL10) protein and promotes tumor cell survival in serum deprivation |
| Q30832574 | HIF-1alpha and HIF-2alpha play a central role in stretch-induced but not shear-stress-induced angiogenesis in rat skeletal muscle |
| Q38066120 | HIFs, angiogenesis, and cancer |
| Q40061651 | Hypoxia enhances the effect of lipopolysaccharide-stimulated IL-1β expression in human periodontal ligament cells |
| Q36470446 | Hypoxia-Inducible Factor-1: A Critical Player in the Survival Strategy of Stressed Cells |
| Q24597508 | IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3) |
| Q36835817 | Improving metabolic stability of cancer chemoprotective polyphenols |
| Q42105077 | Inhibition of Hypoxia-Induced Cell Motility by p16 in MDA-MB-231 Breast Cancer Cells |
| Q28300710 | Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids |
| Q44409387 | Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1. |
| Q44932323 | Isolation of six isoprenylated biflavonoids from the leaves of Garcinia subelliptica |
| Q35210298 | Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway |
| Q37406640 | Kaempferol inhibits angiogenesis and VEGF expression through both HIF dependent and independent pathways in human ovarian cancer cells |
| Q38991674 | Loss of SNAIL inhibits cellular growth and metabolism through the miR-128-mediated RPS6KB1/HIF-1α/PKM2 signaling pathway in prostate cancer cells |
| Q36068139 | Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass? |
| Q33596822 | Methylation of dietary flavones increases their metabolic stability and chemopreventive effects |
| Q35839826 | MiR-128 inhibits tumor growth and angiogenesis by targeting p70S6K1. |
| Q36915053 | MiRNA-181b suppresses IGF-1R and functions as a tumor suppressor gene in gliomas |
| Q47616223 | MicroRNA-26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor-cMet pathway |
| Q90102261 | Microvesicles derived from human bone marrow mesenchymal stem cells promote U2OS cell growth under hypoxia: the role of PI3K/AKT and HIF-1α |
| Q37943792 | Modulation of hypoxia-inducible factors (HIF) from an integrative pharmacological perspective |
| Q39369473 | Molecular targets of dietary phytochemicals for possible prevention and therapy of uterine fibroids: Focus on fibrosis. |
| Q24630499 | Molecular targets of nutraceuticals derived from dietary spices: potential role in suppression of inflammation and tumorigenesis |
| Q34351264 | Natural product MDM2 inhibitors: anticancer activity and mechanisms of action. |
| Q33235403 | Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1). |
| Q57496075 | Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine |
| Q90642646 | Neem Leaf Glycoprotein Restrains VEGF Production by Direct Modulation of HIF1α-Linked Upstream and Downstream Cascades |
| Q35449110 | Negative regulation of HIF-1α by an FBW7-mediated degradation pathway during hypoxia |
| Q64928182 | Nicotine promotes the development of non-small cell lung cancer through activating LINC00460 and PI3K/Akt signaling. |
| Q36096972 | Oral administration of apigenin inhibits metastasis through AKT/P70S6K1/MMP-9 pathway in orthotopic ovarian tumor model |
| Q28383083 | PI3K/PTEN signaling in angiogenesis and tumorigenesis |
| Q23914949 | PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis |
| Q87972132 | Pharmacokinetic drug interactions between apigenin, rutin and paclitaxel mediated by P-glycoprotein in rats |
| Q39584927 | Phosphatidylinositol 3'-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1(alpha) and vascular endothelial growth factor expression |
| Q33606387 | Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study |
| Q49333292 | Plant flavone apigenin: An emerging anticancer agent |
| Q25256110 | Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice |
| Q54457050 | Protein kinase B phosphorylation correlates with vascular endothelial growth factor A and microvessel density in gastric adenocarcinoma. |
| Q39696733 | Q39, a quinoxaline 1,4-Di-N-oxide derivative, inhibits hypoxia-inducible factor-1α expression and the Akt/mTOR/4E-BP1 signaling pathway in human hepatoma cells |
| Q37524156 | Recent advances in validating MDM2 as a cancer target. |
| Q38042021 | Recent agents targeting HIF-1α for cancer therapy |
| Q36860735 | Red orange: experimental models and epidemiological evidence of its benefits on human health |
| Q23910931 | Regulation of angiogenesis and tumor growth by p110 alpha and AKT1 via VEGF expression |
| Q36571008 | Regulation of the p14ARF-Mdm2-p53 pathway: an overview in breast cancer |
| Q36844334 | Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment |
| Q37322759 | Subtoxic Levels of Apigenin Inhibit Expression and Secretion of VEGF by Uveal Melanoma Cells via Suppression of ERK1/2 and PI3K/Akt Pathways |
| Q39405956 | Suppression of hypoxia-inducible factor-1α contributes to the antiangiogenic activity of red propolis polyphenols in human endothelial cells. |
| Q35030217 | Targeting MDM2-p53 interaction for cancer therapy: are we there yet? |
| Q36913614 | Targeting signaling pathways in epithelial ovarian cancer |
| Q38070195 | Targeting the PI3K/Akt/mTOR axis by apigenin for cancer prevention |
| Q37781872 | Targeting tissue oxidative damage by means of cell signaling modulators: The antioxidant concept revisited |
| Q42123168 | The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors |
| Q38952536 | The collagen triple helix repeat containing 1 facilitates hepatitis B virus-associated hepatocellular carcinoma progression by regulating multiple cellular factors and signal cascades |
| Q39185765 | The functional interplay between the HIF pathway and the ubiquitin system - more than a one-way road. |
| Q37798134 | The roles of phytochemicals in bronchial asthma. |
| Q53338021 | The tumour microenvironment as a target for chemoprevention. |
| Q36525391 | Theaflavin-3, 3'-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways |
| Q40232484 | Transactivation of epidermal growth factor receptor by insulin-like growth factor 1 requires basal hydrogen peroxide |
| Q40012625 | UVB induces a biphasic response of HIF-1alpha in cultured human keratinocytes. |
| Q38788965 | Valproic acid inhibits the angiogenic potential of cervical cancer cells via HIF-1α/VEGF signals |
| Q88766145 | miR-155 inhibits the formation of hypertrophic scar fibroblasts by targeting HIF-1α via PI3K/AKT pathway |
| Q36544702 | sMEK1 inhibits endothelial cell proliferation by attenuating VEGFR-2-dependent-Akt/eNOS/HIF-1α signaling pathways |
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