Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma.

scientific article published on December 2004

Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JHEP.2004.08.024
P698PubMed publication ID15582135
P5875ResearchGate publication ID8146039

P50authorDetlef SchuppanQ17418245
P2093author name stringMartin Zeitz
Hans Scherübl
Alexander Huether
Andreas P Sutter
Michael Höpfner
P2860cites workControlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell lineQ40298371
P433issue6
P304page(s)1008-1016
P577publication date2004-12-01
P1433published inJournal of HepatologyQ15724402
P1476titleTargeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma.
P478volume41

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cites work (P2860)
Q33987671A systems biology-based classifier for hepatocellular carcinoma diagnosis
Q90475067Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer
Q57023556Benzofuran-appended 4-aminoquinazoline hybrids as epidermal growth factor receptor tyrosine kinase inhibitors: synthesis, biological evaluation and molecular docking studies
Q39869486Chromogenic in situ hybridization analysis of Epidermal Growth Factor Receptor gene/chromosome 7 numerical aberrations in hepatocellular carcinoma based on tissue microarrays
Q42546774Classifier of cross talk genes predicts the prognosis of hepatocellular carcinoma
Q35231826Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells
Q36147887Comparison of Helicobacter bilis-Associated Protein Expression in Huh7 Cells Harbouring HCV Replicon and in Replicon-Cured Cells
Q34539948Could HBx protein expression affect signal pathway inhibition by gefitinib or selumetinib, a MEK inhibitor, in hepatocellular carcinoma cell lines?
Q91480122Cyclooxygenase-2 in gastrointestinal malignancies
Q37378968Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor
Q35566362Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury
Q52822419Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents.
Q36519010Dysregulation of growth factor signaling in human hepatocellular carcinoma.
Q26771265EGFR Signaling in Liver Diseases
Q39362619EGFR activation is a potential determinant of primary resistance of hepatocellular carcinoma cells to sorafenib
Q34282375EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation
Q40238980EGFR is phosphorylated at Ty845 in hepatocellular carcinoma
Q33248446Effect of blocking IGF-I receptor on growth of human hepatocellular carcinoma cells
Q38161361Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer.
Q34382777Exploiting novel molecular targets in gastrointestinal cancers.
Q37644850FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop
Q53630404Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells.
Q36446915Gefitinib: an adverse effects profile
Q43141124Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer
Q34568677Growth suppression of human hepatocellular carcinoma xenografts by a monoclonal antibody CH12 directed to epidermal growth factor receptor variant III
Q37821305Hepatic cancer stem cells and drug resistance: Relevance in targeted therapies for hepatocellular carcinoma.
Q34499002Hepatitis C virus-mediated angiogenesis: molecular mechanisms and therapeutic strategies.
Q29615767Hepatocellular carcinoma pathogenesis: from genes to environment
Q59789600Icotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression
Q37003601Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma
Q41434771Impact of epidermal growth factor receptor protein and gene alteration on Taiwanese hepatocellular carcinomas
Q41169751In vivo and in vitro effects of QHF combined with chemotherapy on hepatocellular carcinoma
Q30372076In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft.
Q39281043Mechanisms involved in PGE2-induced transactivation of the epidermal growth factor receptor in MH1C1 hepatocarcinoma cells
Q89861316Molecular Signaling Pathways and Therapeutic Targets in Hepatocellular Carcinoma
Q37370027Molecular targeted therapy for hepatocellular carcinoma
Q36740642New molecular targets for hepatocellular carcinoma: the ErbB1 signaling system
Q36883798New perspectives and strategy research biomarkers for hepatocellular carcinoma.
Q36519041New therapies for hepatocellular carcinoma.
Q39692519Novel compounds with antiangiogenic and antiproliferative potency for growth control of testicular germ cell tumours
Q38615458Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids.
Q34940971Novel therapeutic strategies for targeting liver cancer stem cells
Q33635033Oncolytic Virus-Based Immunotherapies for Hepatocellular Carcinoma.
Q61814436Oxazole-Bridged Combretastatin A-4 Derivatives with Tethered Hydroxamic Acids: Structure⁻Activity Relations of New Inhibitors of HDAC and/or Tubulin Function
Q34364217Peritumoral small ephrinA5 isoform level predicts the postoperative survival in hepatocellular carcinoma
Q39799281Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
Q36247086Prediction of liver injury induced by chemicals in human with a multiparametric assay on isolated mouse liver mitochondria
Q36233866Prognosis of hepatocellular carcinoma expressing cytokeratin 19: comparison with other liver cancers
Q64097554Promotion of growth factor signaling as a critical function of β-catenin during HCC progression
Q90094407Reimaging biological barriers affecting distribution and extravasation of PEG/peptide- modified liposomes in xenograft SMMC7721 tumor
Q40238825Signaling pathways involved in the inhibition of epidermal growth factor receptor by erlotinib in hepatocellular cancer.
Q38487106Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development
Q37413127Synergistic activity of vorinostat combined with gefitinib but not with sorafenib in mutant KRAS human non-small cell lung cancers and hepatocarcinoma.
Q64890999Synthesis, Biological Evaluation and Molecular Docking of Novel Indole-Aminoquinazoline Hybrids for Anticancer Properties.
Q38992642Synthesis, molecular docking and biological evaluation of glycyrrhizin analogs as anticancer agents targeting EGFR.
Q37702506Targeted therapy in gastrointestinal malignancies
Q37674624Targeted therapy of hepatocellular cancer.
Q64086947Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma
Q28820734The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models
Q51093729The anti-diabetic drug exenatide, a glucagon-like peptide-1 receptor agonist, counteracts hepatocarcinogenesis through cAMP-PKA-EGFR-STAT3 axis.
Q35081944The effects of a novel MEK inhibitor PD184161 on MEK-ERK signaling and growth in human liver cancer.
Q37773788The role of signaling pathways in the development and treatment of hepatocellular carcinoma
Q38008950Translational medicine in hepatocellular carcinoma
Q37686529Tyrosine kinase inhibitors to treat liver cancer
Q39769976Tyrosine kinase of insulin-like growth factor receptor as target for novel treatment and prevention strategies of colorectal cancer
Q79317745[Anti-EGFR therapy: towards a "à la carte" targeting of hepatocellular carcinoma]
Q80554209[Molecular pathogenesis of hepatocellular carcinoma: new therapeutic approaches and predictive pathology]

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