Icotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression

Icotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/OTT.S179844
P932PMC publication ID6254541
P698PubMed publication ID30538492

P2093author name stringZhongyang Shen
Qingjun Guo
Wentao Jiang
Jisan Sun
Dazhi Tian
P2860cites workMolecular signatures in hepatocellular carcinoma: A step toward rationally designed cancer therapy.Q52583955
Clinical analysis by next-generation sequencing for NSCLC patients with MET amplification resistant to osimertinib.Q52639687
Gefitinib and the modulation of the signaling pathways downstream of epidermal growth factor receptor in human liver cancer cells.Q53630404
Icotinib enhances lung cancer cell radiosensitivity in vitro and in vivo by inhibiting MAPK/ERK and AKT activation.Q54109233
Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer.Q54339119
Continuous improvement of survival outcomes of resection of hepatocellular carcinoma: a 20-year experienceQ83809945
Marked Response to Icotinib in Lung Squamous Cell Carcinoma with EGFR Wild-TypeQ88982783
Hepatocellular carcinoma: a reviewQ28069290
Hepatocellular carcinomaQ29615765
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials GroupQ29619344
Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinomaQ33863710
Icotinib (BPI-2009H), a novel EGFR tyrosine kinase inhibitor, displays potent efficacy in preclinical studiesQ34082260
The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell ProliferationQ36518331
Induction of PD-L1 expression by epidermal growth factor receptor-mediated signaling in esophageal squamous cell carcinomaQ37650062
Targeting the ERBB family in cancer: couples therapyQ38129286
Advances in targeted therapies for hepatocellular carcinoma in the genomic era.Q38521011
The role of JAK/STAT3 signaling pathway on apoptosis of lung adenocarcinoma cell line PC-9 induced by icotinibQ38770483
EGFR-TKI down-regulates PD-L1 in EGFR mutant NSCLC through inhibiting NF-κB.Q38872276
Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR MutationQ38912283
Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumorsQ39089944
Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells.Q39996225
Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma.Q40463024
Analysis of liver cancer incidence and trend in ChinaQ40949376
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosisQ45231150
EGFR-PI3K-PDK1 pathway regulates YAP signaling in hepatocellular carcinoma: the mechanism and its implications in targeted therapy.Q49958316
PD-L1 expression according to the EGFR status in primary lung adenocarcinomaQ50139973
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)8227-8237
P577publication date2018-01-01
P1433published inOncoTargets and TherapyQ7092081
P1476titleIcotinib inhibits the proliferation of hepatocellular carcinoma cells in vitro and in vivo dependently on EGFR activation and PDL1 expression
P478volume11

Reverse relations

cites work (P2860)
Q100490607Advances in targeted therapy for esophageal cancer
Q89624059Recent advances in liver transplantation for cancer: The future of transplant oncology

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