bcl‐2, a novel reguator of cell death

scientific article published on July 1, 1995

bcl‐2, a novel reguator of cell death is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1002/BIES.950170709
P953full work available at URLhttps://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbies.950170709
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.950170709
P698PubMed publication ID7646485

P50authorDavid HockenberyQ110718522
P2093author name stringD. M. Hockenbery
P2860cites workbcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell deathQ24312157
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathQ24312211
Molecular cloning of the interleukin-1 beta converting enzymeQ24338607
MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2Q24563123
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsQ24564912
Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2Q28237519
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytesQ28237565
Bcl-2 associates with the ras-related protein R-ras p23Q28256068
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzymeQ28256420
Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarinsQ28266921
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cellsQ28294137
Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell deathQ28507741
Bcl-2 expression promotes B- but not T-lymphoid development in scid miceQ28508352
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hairQ28586758
Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3Q28645710
Induction of apoptosis in fibroblasts by c-myc proteinQ29614346
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell deathQ29620000
Bcl-2 functions in an antioxidant pathway to prevent apoptosisQ29620401
Genetic control of programmed cell death in the nematode C. elegans.Q34196702
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.Q34322094
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzymeQ34325458
Prevention of vertebrate neuronal death by the crmA geneQ34349314
p53 and E2F-1 cooperate to mediate apoptosisQ35185411
Activation of cyclin A-dependent protein kinases during apoptosisQ35195381
c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycleQ35538874
Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.Q35774469
Bcl-2 and the regulation of programmed cell deathQ36233600
bcl-2 inhibits death of central neural cells induced by multiple agentsQ36303360
Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free mediumQ36315481
A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoterQ36686916
Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytesQ36819033
Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.Q37554227
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell deathQ37572590
Death by suicide: one way to go in mammalian cellular development?Q37774724
Molecular regulation of apoptosis: genetic controls on cell death.Q40712883
Oxidative stress as a mediator of apoptosisQ40729167
Oncogenes and cell deathQ40757516
Programmed cell death and the control of cell survival: lessons from the nervous systemQ40777905
The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.Q40874517
Analysis of susceptibility of mature human T lymphocytes to dexamethasone-induced apoptosisQ41469366
Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.Q41509622
Bcl-2 inhibition of neural death: decreased generation of reactive oxygen speciesQ41513775
Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factorsQ41528217
Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation.Q41575182
Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosisQ41671465
Tumour necrosis factor-induced cytotoxicity is accompanied by intracellular mitogenic signals in ME-180 human cervical carcinoma cellsQ42070324
Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosisQ42156172
Susceptibility to cytotoxic T lymphocyte-induced apoptosis is a function of the proliferative status of the targetQ42801965
Continuous c-fos expression precedes programmed cell death in vivoQ42809601
Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factorQ46254405
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.Q48377324
Premature p34cdc2 activation required for apoptosis.Q52514157
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.Q52514947
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.Q54515149
Ultrastructural localization of bcl-2 proteinQ67594726
Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferationQ68821821
Involvement of the bcl-2 gene in human follicular lymphomaQ69870224
Cdc2 activation is not required for thymocyte apoptosisQ72128900
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control pointsQ72628282
High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitroQ72636726
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectcell deathQ2383867
P304page(s)631-638
P577publication date1995-07-01
P1433published inBioEssaysQ4914614
P1476titlebcl‐2, a novel reguator of cell death
P478volume17

Reverse relations

cites work (P2860)
Q37537012A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells
Q28573793Activation of retinoic acid receptor gamma induces proliferation of immortalized hippocampal progenitor cells
Q28583270Adenovirus E1A inhibits cardiac myocyte-specific gene expression through its amino terminus
Q30650857Aldehydic lipid peroxidation products derived from linoleic acid
Q73468224Apoptosis and cutaneous biology
Q41280990Apoptosis in the heart: when and why?
Q36954229Apoptosis status and proliferative activity in mucopolysaccharidosis type I mice tongue mucosa cells
Q48537871Apoptosis-related protein expression in the hippocampus in Alzheimer's disease
Q48579758Apoptosis-suppressor gene bcl-2 expression after traumatic brain injury in rats.
Q38025197BCL-2 family of proteins and mammary cellular fate
Q38358357Binding of DNA oligonucleotides to sequences in the promoter of the human bc1-2 gene
Q41740220Biochemical and molecular mechanisms regulating apoptosis
Q77441937Correlation of proliferation indices, apoptosis, and related oncogene expression (bcl-2 and c-erbB-2) and p53 in proliferative, hyperplastic, and malignant endometrium
Q47754209Cytotoxicity and apoptosis induction of sodium fluoride in human promyelocytic leukemia (HL-60) cells
Q33853014Drug delivery to mitochondria: the key to mitochondrial medicine
Q35763713Enhanced lymphocyte longevity and absence of proliferation and lymphocyte apoptosis in Quilty effects of human heart allografts
Q31383649Evidence for the induction of apoptosis by endosulfan in a human T-cell leukemic line
Q60368043Explaining Aberrations of Cell Structure and Cell Signaling in Cancer Using Complex Adaptive Systems
Q47680789Expression of the bcl-2 protein in the developing human brain.
Q47748978Expressions and localizations of Bax/Bcl-2 proteins during metamorphosis of Pelophylax ridibundus
Q73298818Flow cytometric detection of spontaneous apoptosis in human breast cancer using the TUNEL-technique
Q42483084Influence of age on hypoxia/reoxygenation-induced DNA fragmentation and bcl-2, bcl-xl, bax and fas in the rat heart and brain
Q47860807Localization of Bcl-2 in the human fetal müllerian tract
Q43866759Maternal immune stimulation in mice decreases fetal malformations caused by teratogens
Q40648293Minor influence of the immunosuppressive cytokines IL-10 and TGF-beta on the proliferation and apoptosis of human retinal pigment epithelial (RPE) cells in vitro
Q33991805Mitochondrially targeted antioxidants and thiol reagents
Q73168796Modeling signal transduction in normal and cancer cells using complex adaptive systems
Q40916918Myeloperoxidase-catalyzed redox-cycling of phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells
Q46834723Neurotoxic effects of alcohol and acetaldehyde during embryonic development
Q52189581Neurulation abnormalities secondary to altered gene expression in neural tube defect susceptible Splotch embryos.
Q43864425Oxidant-antioxidant status in relation to survival among breast cancer patients
Q74341665Oxidative stress and apoptosis
Q35051324Receptor activator for nuclear factor-κB ligand signaling promotes progesterone-mediated estrogen-induced mammary carcinogenesis
Q71825443Recombinant mouse Bcl-2(1-203). Two domains connected by a long protease-sensitive linker
Q77994180Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells
Q35668841Roles of ERβ and GPR30 in Proliferative Response of Human Bladder Cancer Cell to Estrogen
Q41111127Stopping death cold
Q39270781Synergistic effects of acute warming and low pH on cellular stress responses of the gilthead seabream Sparus aurata.
Q41515265The Fas pathway in apoptosis.
Q36332092The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathway
Q40020332Translational control of programmed cell death: eukaryotic translation initiation factor 4E blocks apoptosis in growth-factor-restricted fibroblasts with physiologically expressed or deregulated Myc.
Q55474326TrkA induces differentiation but not apoptosis in C6-2B glioma cells.
Q41056239Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells
Q37484075bcl-2 overexpression reduces apoptotic photoreceptor cell death in three different retinal degenerations

Search more.