BCL-2 family of proteins and mammary cellular fate

scientific article published on 16 January 2012

BCL-2 family of proteins and mammary cellular fate is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1439-0264.2012.01134.X
P698PubMed publication ID22780877

P2093author name stringM Colitti
P2860cites workBcl-x(L) retrotranslocates Bax from the mitochondria into the cytosolQ24298758
Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by BaxQ24323186
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosisQ24533270
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentationQ24642901
Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivationQ24643422
Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesisQ24681265
Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosisQ28141949
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosisQ28189945
Cell death: critical control pointsQ28240722
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and deathQ28363890
BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanismsQ28510331
Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscleQ28574883
Bax and Bcl-xs are induced at the onset of apoptosis in involuting mammary epithelial cellsQ28586726
Enhanced oxidative stress and altered antioxidants in brains of Bcl-2-deficient miceQ28593905
The BCL-2 protein family: opposing activities that mediate cell deathQ29547380
Cell death: the significance of apoptosisQ29617620
Bcl-2 functions in an antioxidant pathway to prevent apoptosisQ29620401
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeuticsQ29620467
Expression of apoptosis-related proteins in involuting mammary gland of sow.Q33181862
Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.Q33688622
Mammary involution in dairy animalsQ33699402
Bcl-2 gene family and related proteins in mammary gland involution and breast cancerQ33699417
The Bcl-2 protein familyQ33876776
Mitochondria as the central control point of apoptosisQ33994978
Redox aspects of Bcl-2 function.Q34169008
The JAK/STAT signaling pathwayQ34305849
Bax and other pro-apoptotic Bcl-2 family "killer-proteins" and their victim the mitochondrionQ34458015
Potentiation of cellular antioxidant capacity by Bcl-2: implications for its antiapoptotic functionQ35557570
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.Q35857078
Antioxidant dietary supplementation in mice exposed to proton radiation attenuates expression of programmed cell death-associated genesQ36057799
Mammary-derived signals activate programmed cell death during the first stage of mammary gland involutionQ36086481
Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization.Q36328358
Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cellsQ36563824
Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein baxQ36989962
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteinsQ37309119
Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF).Q37759802
Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2.Q37864354
Compensatory nutrition-directed mammary cell proliferation and lactation in ratsQ38529194
Mammary gland function during involutionQ38673567
Metabolic adaptations in mammary gland during the declining phase of lactationQ38673582
The Bcl-2 homology domain 3 (BH3) mimetic ABT-737 reveals the dynamic regulation of bad, a proapoptotic protein of the Bcl-2 family, by Bcl-xL.Q39577886
Apoptosis commitment and activation of mitochondrial Bax during anoikis is regulated by p38MAPK.Q39815661
Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cellsQ40131176
bcl‐2, a novel reguator of cell deathQ40466009
Oxidative stress as a mediator of apoptosisQ40729167
NH2-terminal BH4 domain of Bcl-2 is functional for heterodimerization with Bax and inhibition of apoptosisQ40943000
The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosisQ41002686
Functional dissection of Bfl-1, a Bcl-2 homolog: anti-apoptosis, oncogene-cooperation and cell proliferation activitiesQ41023887
Bcl-2 overexpression in the HaCaT cell line is associated with a different membrane fatty acid composition and sensitivity to oxidative stressQ41070819
Traveling Bax and forth from mitochondria to control apoptosis.Q41869309
Cell turnover and gene activities in sheep mammary glands prior to lambing to involutionQ42451517
Postnatal mammary ductal growth: three-dimensional imaging of cell proliferation, effects of estrogen treatment, and expression of steroid receptors in prepubertal calvesQ42524894
Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processingQ43204012
Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation.Q43814258
BCL-2 is involved in preventing oxidant-induced cell death and in decreasing oxygen radical production.Q43897073
Impact of high-fat diet and antioxidant supplement on mitochondrial functions and gene transcripts in rat muscleQ43948684
Concurrent pregnancy retards mammary involution: effects on apoptosis and proliferation of the mammary epithelium after forced weaning of miceQ43967658
Morphometric analysis of involuting bovine mammary tissue after 21 or 42 days on non-sucklingQ44975831
Bcl-2 family proteins regulate mitochondrial reactive oxygen production and protect against oxidative stressQ45140387
Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) releaseQ46525695
alpha-Tocopheryl succinate induces apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functionQ46977941
Detection of apoptosis-inducing factor in involuting mammary tissue by immunoelectron microscopy.Q47994191
Expression of a putative stem cell marker, Musashi 1, in mammary glands of ewes.Q51931965
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.Q52514947
Modulation of mammary development and programmed cell death by the frequency of milk removal in lactating goatsQ58377558
Programmed cell death in bovine mammary tissue during lactation and involutionQ58377561
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectprotein familyQ417841
P304page(s)237-247
P577publication date2012-01-16
P1433published inAnatomia, Histologia, EmbryologiaQ2533747
P1476titleBCL-2 family of proteins and mammary cellular fate
P478volume41

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cites work (P2860)
Q54348802Antioxidant and antiproliferative activities of methanolic extract from a neglected agricultural product: corn cobs.
Q57552258Effects of Furanodiene on 95-D Lung Cancer Cells: Apoptosis, Autophagy and G1 Phase Cell Cycle Arrest
Q50524951Huannao Yicong Decoction () extract reduces inflammation and cell apoptosis in Aβ1-42-induced Alzheimer's disease model of rats.
Q34096391Mechanism underlying the protective effect of Kaixin Jieyu Fang on vascular depression following cerebral white matter damage
Q42518356MicroRNA in the ovine mammary gland during early pregnancy: spatial and temporal expression of miR-21, miR-205, and miR-200.
Q40297064Proliferation-apoptosis balance in Staphylococcus aureus chronically infected bovine mammary glands during involution
Q33588077The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland.
Q38707925miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy

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