Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents.

scientific article published on 12 September 2016

Identification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BMC.2016.09.027
P932PMC publication ID5065789
P698PubMed publication ID27663549

P50authorLindsey N ShawQ56191691
P2093author name stringRichard A Houghten
Hongjie Wang
Yangmei Li
Nina Bionda
Akihiko Ozawa
Renee Fleeman
P2860cites workCorrelation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.Q42050161
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Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationshipQ44006954
Inhibition of daptomycin by pulmonary surfactant: in vitro modeling and clinical impactQ46494181
Invasive methicillin-resistant Staphylococcus aureus infections in the United StatesQ29616087
Linezolid for the treatment of multidrug-resistant, gram-positive infections: experience from a compassionate-use programQ33346036
In vitro and in vivo activities of tigecycline (GAR-936), daptomycin, and comparative antimicrobial agents against glycopeptide-intermediate Staphylococcus aureus and other resistant gram-positive pathogensQ34110412
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.Q34214929
Chiral drugs: an overviewQ34344756
Adenylate kinase release as a high-throughput-screening-compatible reporter of bacterial lysis for identification of antibacterial agentsQ34425938
DNA gyrase: structure and function.Q34507230
In vitro characterization of the antibacterial spectrum of novel bacterial type II topoisomerase inhibitors of the aminobenzimidazole classQ34510396
Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureusQ34747322
TigecyclineQ36205663
The emergence of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureusQ36381504
Naturally occurring and synthetic imidazoles: their chemistry and their biological activitiesQ36386412
Mechanisms of daptomycin resistance in Staphylococcus aureus: role of the cell membrane and cell wallQ36565462
Alternatives to vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infectionsQ36916071
Utility of Greater Wax Moth Larva (Galleria mellonella) for Evaluating the Toxicity and Efficacy of New Antimicrobial Agents.Q42014294
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)5633-5638
P577publication date2016-09-12
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleIdentification of 5,6-dihydroimidazo[2,1-b]thiazoles as a new class of antimicrobial agents
P478volume24

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Q48509625Identification of a small molecule inhibitor of the aminoglycoside 6'-N-acetyltransferase type ib [AAC(6')-ib] using mixture-based combinatorial librariescites workP2860

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