Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae

scientific article published on September 2004

Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1001198838
P356DOI10.1038/SJ.ONC.1207911
P698PubMed publication ID15273741
P5875ResearchGate publication ID8435484

P2093author name stringAbedelnasser Abulrob
Moises F Andrade
Maria Moreno
Danica Stanimirovic
Angela McDermid
Sabina Giuseppin
P2860cites workReciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancerQ24318999
Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivoQ24324547
Caveolin-1, a putative tumour suppressor geneQ28212075
Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activitiesQ28255025
Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomasQ28359685
The caveolae membrane systemQ29614726
Lipid domain structure of the plasma membrane revealed by patching of membrane componentsQ29620204
Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalizationQ30164745
Identification of differentially expressed proteins in human glioblastoma cell lines and tumorsQ31136179
Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implicationsQ31867049
Metastasis-related genes in prostate cancer: the role of caveolin-1.Q33715218
A detergent-free method for purifying caveolae membrane from tissue culture cellsQ33818572
Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascadeQ33890028
Caveolins in cholesterol trafficking and signal transduction: implications for human disease.Q34095985
A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptorQ34470390
A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicityQ35660849
Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human diseaseQ36234407
Aggregation of lipid rafts accompanies signaling via the T cell antigen receptorQ36326042
Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblastsQ37284379
Caveolin-1 expression is maintained in rat and human astroglioma cell linesQ40749203
Effect of membrane fluidity on tyrosine kinase activity of reconstituted epidermal growth factor receptorQ40799906
Regulated migration of epidermal growth factor receptor from caveolaeQ40923075
Reduction of caveolin 1 gene expression in lung carcinoma cell linesQ40970296
Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membraneQ41715384
Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trialsQ41718736
Proliferation of human and mouse astrocytes in vitro: signalling through the protein kinase C pathwayQ42455721
Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptorQ42808936
Caveolin-associated filamentous actin (Cav-actin) defines a novel F-actin structure in adipocytesQ42814557
Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domainQ47881243
Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell typesQ48335445
The expression of rho proteins decreases with human brain tumor progression: potential tumor markersQ48649169
Radioiodinated (I-125) monoclonal antibody 425 in the treatment of high grade glioma patients: ten-year synopsis of a novel treatment.Q55473118
Epidermal Growth Factor-stimulated Tyrosine Phosphorylation of Caveolin-1Q57371816
Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membraneQ71142838
Polyubiquitination of the epidermal growth factor receptor occurs at the plasma membrane upon ligand-induced activationQ73731460
Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stageQ77838885
P433issue41
P407language of work or nameEnglishQ1860
P921main subjectglioblastomaQ282142
phosphorylationQ242736
P304page(s)6967-6979
P577publication date2004-09-01
P1433published inOncogeneQ1568657
P1476titleInteractions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae
P478volume23

Reverse relations

cites work (P2860)
Q89824094A High-Throughput Method for Characterizing Novel Chimeric Antigen Receptors in Jurkat Cells
Q48092346A Poly(Propyleneimine) Dendrimer-Based Polyplex-System for Single-Chain Antibody-Mediated Targeted Delivery and Cellular Uptake of SiRNA.
Q41934121A dual role for caveolin-1 in the regulation of fibronectin matrix assembly by uPAR.
Q24301296Abi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosis
Q40192630Activated epidermal growth factor receptor induces integrin alpha2 internalization via caveolae/raft-dependent endocytic pathway
Q91535366Apoptosis of cancer cells is triggered by selective crosslinking and inhibition of receptor tyrosine kinases
Q33802553Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy.
Q36923326Caveolin-1 is a negative regulator of tumor growth in glioblastoma and modulates chemosensitivity to temozolomide
Q59795879Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy
Q37438194Caveolin-1 orchestrates TCR synaptic polarity, signal specificity, and function in CD8 T cells
Q36800478Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells
Q35173015Caveolin-1 regulates osteoclastogenesis and bone metabolism in a sex-dependent manner
Q34222800Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition
Q36010112Caveolin-1, caveolae, and glioblastoma
Q36994563Caveolins in glial cell model systems: from detection to significance
Q63681516Correlation of the invasive potential of glioblastoma and expression of caveola-forming proteins caveolin-1 and CAVIN1
Q26801397Decoding the Matrix: Instructive Roles of Proteoglycan Receptors
Q36578803Decorin as a multivalent therapeutic agent against cancer.
Q40402570Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis
Q33712312Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol
Q39321309EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells
Q38199643EGFR-dependent mechanisms in glioblastoma: towards a better therapeutic strategy.
Q40156909EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes
Q36508737EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins
Q40262046Effect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sorting
Q34681404Eph-B4 prevents venous adaptive remodeling in the adult arterial environment
Q34722511Epidermal growth factor receptor and caveolin-1 coexpression identifies adult supratentorial ependymomas with rapid unfavorable outcomes
Q64057602Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma
Q28397739Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
Q57362555Expression of caveolin-1 is correlated with Akt-1 in colorectal cancer tissues
Q92285599Ganglioside GM1 promotes contact inhibition of growth by regulating the localization of epidermal growth factor receptor from glycosphingolipid-enriched microdomain to caveolae
Q35882401Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1
Q40820782Identification of Glioblastoma Phosphotyrosine-Containing Proteins with Two-Dimensional Western Blotting and Tandem Mass Spectrometry
Q36038735Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression
Q40759373Integrin alpha1beta1 regulates epidermal growth factor receptor activation by controlling peroxisome proliferator-activated receptor gamma-dependent caveolin-1 expression
Q34112887Kinetic analysis of novel mono- and multivalent VHH-fragments and their application for molecular imaging of brain tumours.
Q48102903Microarray analysis of gliomas reveals chromosomal position-associated gene expression patterns and identifies potential immunotherapy targets.
Q33661563Nanoscale imaging of epidermal growth factor receptor clustering: effects of inhibitors
Q90670412New glimpses of caveolin-1 functions in embryonic development and human diseases
Q37676970Nuclear EGFR as novel therapeutic target: insights into nuclear translocation and function
Q52145779Nucleolin overexpression is associated with an unfavorable outcome for ependymoma: a multifactorial analysis of 176 patients.
Q43073039Oligodendroglial process formation is differentially affected by modulating the intra- and extracellular cholesterol content
Q28538029Polymerase I and transcript release factor acts as an essential modulator of glioblastoma chemoresistance
Q36397535Reovirus uses multiple endocytic pathways for cell entry.
Q39259413Selection of reference genes for use in quantitative reverse transcription PCR assays when using interferons in U87MG.
Q37362819Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo
Q38650902TIE2 associates with caveolae and regulates caveolin-1 to promote their nuclear translocation
Q40008856Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells
Q27015045The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered
Q51416808The role of PTRF/Cavin1 as a biomarker in both glioma and serum exosomes.
Q24304487The role of insulin-like growth factor binding protein-3 in the breast cancer cell response to DNA-damaging agents
Q37437211c-Src/Cav1-dependent activation of the EGFR by Dsg2
Q99565629miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas

Search more.