Oxidative stress in Parkinson's disease

scientific article published on February 1995

Oxidative stress in Parkinson's disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1365-2990.1995.TB01022.X
P698PubMed publication ID7770118

P2093author name stringSchapira AH
P2860cites workChronic Parkinsonism in humans due to a product of meperidine-analog synthesisQ22242250
A large kindred with autosomal dominant Parkinson's diseaseQ28237850
Ageing and Parkinson's disease: substantia nigra regional selectivityQ29615835
Alpha-tocopherol levels in brain are not altered in Parkinson's diseaseQ33194048
Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's diseaseQ33220863
Normal mitochondrial genome in brain from patients with Parkinson's disease and complex I defectQ33785020
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's diseaseQ33789328
The free radical hypothesis in idiopathic parkinsonism: evidence against itQ35626740
The oxidant stress hypothesis in Parkinson's disease: evidence supporting itQ35626743
Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research GroupQ35753957
Complex I, iron, and ferritin in Parkinson's disease substantia nigraQ36730657
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicityQ37683630
Twin studies and the genetics of Parkinson's disease--a reappraisalQ38124122
NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH–ubiquinone reductase preparationQ39273179
Evidence for mitochondrial dysfunction in Parkinson's disease--a critical appraisalQ40758643
The possible role of iron in the etiopathology of Parkinson's diseaseQ40868666
Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's diseaseQ41346993
Rate of cell death in parkinsonism indicates active neuropathological processQ41417978
Ascorbic acid protects against levodopa-induced neurotoxicity on a catecholamine-rich human neuroblastoma cell lineQ41544515
Parkinson's disease: a disorder due to nigral glutathione deficiency?Q41628096
Neurotoxicity of levodopa on catecholamine-rich neuronsQ41646305
Mitochondrial complex I deficiency in Parkinson's diseaseQ41821730
Decreased ferritin levels in brain in Parkinson's diseaseQ42000755
Alteration of inner-membrane components and damage to electron-transfer activities of bovine heart submitochondrial particles induced by NADPH-dependent lipid peroxidationQ42168031
Brain Peroxidase and Catalase in Parkinson DiseaseQ44295221
Sequential damage in mitochondrial complexes by peroxidative stressQ44438376
Basal lipid peroxidation in substantia nigra is increased in Parkinson's diseaseQ44808814
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlationsQ45302799
Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase.Q46015264
Increased nigral iron content in postmortem parkinsonian brainQ48182830
Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.Q48310314
Suppressive effect of L-dopa on dopamine cells remaining in the ventral tegmental area of rats previously exposed to the neurotoxin 6-hydroxydopamineQ48316653
Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patientsQ48331251
Glutathione peroxidase activity in Parkinson's disease brainQ48462475
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridineQ48477579
Quantitation of a mitochondrial DNA deletion in Parkinson's diseaseQ48507765
Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTPQ48590320
Nigrostriatal Dopaminergic Neurons Remain Undamaged in Rats Given High Doses of l-DOPA and Carbidopa ChronicallyQ48619910
Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian BrainsQ48789036
Respiratory activity of isolated rat brain mitochondria following in vitro exposure to oxygen radicalsQ48800877
Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in cultureQ48929977
When did Ray Kennedy's Parkinson's disease begin?Q52392414
Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [3H]dihydrorotenoneQ52461227
P433issue1
P921main subjectParkinson's diseaseQ11085
P304page(s)3-9
P577publication date1995-02-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inNeuropathology and Applied NeurobiologyQ7002494
P1476titleOxidative stress in Parkinson's disease
P478volume21

Reverse relations

cites work (P2860)
Q40838697A biologically motivated partitioning of mortality
Q73661245Age-related changes in reactive oxygen species production in rat brain homogenates
Q42449719Aluminum potentiates glutamate-induced calcium accumulation and iron-induced oxygen free radical formation in primary neuronal cultures
Q28084254Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View
Q48483070Asymmetry of sympathetic activity in a rat model of Parkinson’s disease induced by 6-hydroxydopamine: haemodynamic, electrocardiographic and biochemical changes
Q83262328Challenges to the development of disease‐modifying therapies in Parkinson’s disease
Q48482071Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice
Q46851841Creatine supplementation improves dopaminergic cell survival and protects against MPP+ toxicity in an organotypic tissue culture system
Q41740100Dementia with Lewy Bodies. A Distinct Non‐Alzheimer Dementia Syndrome?
Q35040174Discovery of CEP-1347/KT-7515, an inhibitor of the JNK/SAPK pathway for the treatment of neurodegenerative diseases.
Q43639267Effect of antioxidants on L-glutamate and N-methyl-4-phenylpyridinium ion induced-neurotoxicity in PC12 cells
Q31966978Elevated activity of phospholipid biosynthetic enzymes in substantia nigra of patients with Parkinson's disease.
Q42540598Expanded CTG repeats in myotonin protein kinase increase susceptibility to oxidative stress
Q28475323Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans
Q67212474Genes and parkinsonism.
Q41010065Genetic analysis of ageing: role of oxidative damage and environmental stresses.
Q34747340Human complex I defects in neurodegenerative diseases
Q38663090Huntington's Disease: Pathogenic Mechanisms and Therapeutic Targets.
Q34057625In glaucoma, should enthusiasm about neuroprotection be tempered by the experience obtained in other neurodegenerative disorders?
Q44722680Inhibition of rat brain microsomal cytochrome P450-dependent dealkylation activities by an oxidative stress
Q38085166Lipophilic fluorescent products of free radicals
Q48522703Low activity of key phospholipid catabolic and anabolic enzymes in human substantia nigra: possible implications for Parkinson's disease.
Q48810698Mesencephalic neuron death induced by congeners of nitrogen monoxide is prevented by the lazaroid U-83836E.
Q38762971MiR-144-3p and Its Target Gene β-Amyloid Precursor Protein Regulate 1-Methyl-4-Phenyl-1,2-3,6-Tetrahydropyridine-Induced Mitochondrial Dysfunction
Q37037953Mitochondria in the aetiology and pathogenesis of Parkinson's disease
Q37891820Mitochondrial Contribution to Parkinson's Disease Pathogenesis
Q48844431Mitochondrial DNA polymorphism in substantia nigra
Q33580327Mitochondrial matters of the brain: the role in Huntington's disease
Q37954223Mitochondrial pathology in Parkinson's disease
Q37963572Monoamine oxidase B inhibitors for the treatment of Parkinson's disease: a review of symptomatic and potential disease-modifying effects
Q73101267Nedd2 is required for apoptosis after trophic factor withdrawal, but not superoxide dismutase (SOD1) downregulation, in sympathetic neurons and PC12 cells
Q41718471Neuropathology of Movement Disorders
Q40676919Neuroprotective effects of copper/zinc-dependent superoxide dismutase against a wide variety of death-inducing stimuli and proapoptotic effect of familial amyotrophic lateral sclerosis mutations
Q33545307Neuroprotective therapies.
Q44865152Neurotoxicity of methamphetamine and methylenedioxymethamphetamine
Q64948819Parkinson's disease, amyotrophic lateral sclerosis and spinal muscular atrophy are caused by an unstable (CAG)n trinucleotide repeat microsatellite
Q74363334Peroxide-scavenging deficit underlies oligodendrocyte susceptibility to oxidative stress
Q42727582Protection of dichlorvos induced oxidative stress and nigrostriatal neuronal death by chronic Coenzyme Q10 pretreatment
Q41846352Redistribution of glucose-6-phosphate dehydrogenase in response to cerebral ischemia in rat brain
Q29618019The Free Radical Theory of Aging Matures
Q35061204The combined transduction of copper, zinc-superoxide dismutase and catalase mediated by cell-penetrating peptide, PEP-1, to protect myocardium from ischemia-reperfusion injury
Q41011950Update on the biological characteristics of the antioxidant micronutrients: vitamin C, vitamin E, and the carotenoids
Q73851259Xenobiotic-mediated production of superoxide by primary cultures of rat cerebral endothelial cells, astrocytes, and neurones

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