The basement membrane protein laminin-5 acts as a soluble cell motility factor

scientific article published on July 2004

The basement membrane protein laminin-5 acts as a soluble cell motility factor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXCR.2004.03.044
P698PubMed publication ID15212952

P2093author name stringKaoru Miyazaki
Yoshinobu Kariya
P2860cites workKalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has a different requirement for integrin receptorsQ42770572
Identification of cell-binding sites on the Laminin alpha 5 N-terminal domain by site-directed mutagenesisQ43510805
Integrin alpha3beta1-mediated interaction with laminin-5 stimulates adhesion, migration and invasion of malignant glioma cells.Q55477887
Form and function: the laminin family of heterotrimersQ22254277
A large cell-adhesive scatter factor secreted by human gastric carcinoma cellsQ24563665
Laminin 5 binds the NC-1 domain of type VII collagenQ24676762
Rho GTPases and the actin cytoskeletonQ27860579
Structural requirement of carboxyl-terminal globular domains of laminin alpha 3 chain for promotion of rapid cell adhesion and migration by laminin-5Q28143843
Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathwayQ28190218
Purification and characterization of human laminin-8. Laminin-8 stimulates cell adhesion and migration through alpha3beta1 and alpha6beta1 integrinsQ28208073
Induction of Cell Migration by Matrix Metalloprotease-2 Cleavage of Laminin-5Q28242922
Wide distribution of laminin-5 gamma 2 chain in basement membranes of various human tissuesQ28281035
Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motilityQ28366134
ERM proteins and merlin: integrators at the cell cortexQ29619893
Phosphorylation of a conserved integrin alpha 3 QPSXXE motif regulates signaling, motility, and cytoskeletal engagementQ30500244
Biology and function of hemidesmosomesQ33657765
Mutation analysis and molecular genetics of epidermolysis bullosaQ33657782
Role of cell surface metalloprotease MT1-MMP in epithelial cell migration over laminin-5.Q33843796
Structure and function of laminin LG modulesQ34017802
Deposition of laminin 5 in epidermal wounds regulates integrin signaling and adhesionQ34026266
Rho GTPases: signaling, migration, and invasionQ34084642
Biological and clinical relevance of Laminin-5 in cancerQ34395725
Laminin-5 in the progression of carcinomasQ34464317
Recognition of the laminin E8 cell-binding site by an integrin possessing the alpha 6 subunit is essential for epithelial polarization in developing kidney tubulesQ36223725
Processing of laminin-5 and its functional consequences: role of plasmin and tissue-type plasminogen activatorQ36255285
Cellular interaction of integrin alpha3beta1 with laminin 5 promotes gap junctional communicationQ36255947
Targeted disruption of the LAMA3 gene in mice reveals abnormalities in survival and late stage differentiation of epithelial cellsQ36256553
Laminin-5 inhibits human keratinocyte migration.Q38344960
The new basement membrane antigen recognized by the monoclonal antibody GB3 is a large size glycoprotein: modulation of its expression by retinoic acidQ38346925
The alpha isoform of protein kinase C is involved in signaling the response of desmosomes to wounding in cultured epithelial cellsQ38480496
Characterization of the Ligand-Binding Specificities of Integrin 3 1 and 6 1 Using a Panel of Purified Laminin Isoforms Containing Distinct ChainsQ40618213
Efficient expression system of human recombinant laminin-5.Q40629605
Differential regulation of cellular adhesion and migration by recombinant laminin-5 forms with partial deletion or mutation within the G3 domain of alpha3 chainQ40676802
Laminin-6 is activated by proteolytic processing and regulates cellular adhesion and migration differently from laminin-5.Q40697430
Epidermal differentiation and basement membrane formation by HaCaT cells in surface transplantsQ41042865
Morphogenetic effects of soluble laminin-5 on cultured epithelial cells and tissue explantsQ41155099
Rapid spreading and mature hemidesmosome formation in HaCaT keratinocytes induced by incubation with soluble laminin-5rQ41291086
Marked stimulation of cell adhesion and motility by ladsin, a laminin-like scatter factorQ41440597
The alpha 6 beta 4 integrin is a receptor for both laminin and kalininQ41476163
Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranesQ41683771
Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarityQ41727655
Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filamentsQ41964164
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectmembrane proteinQ423042
P304page(s)508-520
P577publication date2004-07-01
P1433published inExperimental Cell ResearchQ1524289
P1476titleThe basement membrane protein laminin-5 acts as a soluble cell motility factor
P478volume297

Reverse relations

cites work (P2860)
Q33517982A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047.
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Q37640766Adhesion and migration, the diverse functions of the laminin alpha3 subunit.
Q35051524Amino-terminal fragments of laminin γ2 chain retract vascular endothelial cells and increase vascular permeability
Q30493173Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility
Q33717490Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation
Q36627216Experimental models and high-throughput diagnostics for tissue regeneration
Q26785535Galectin-3 as a regulator of the epithelial junction: Implications to wound repair and cancer
Q91562781LAMC2 modulates the acidity of microenvironments to promote invasion and migration of pancreatic cancer cells via regulating AKT-dependent NHE1 activity
Q41197789Laminin-111: a potential therapeutic agent for Duchenne muscular dystrophy
Q48250078Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons
Q40011710Laminin-332 promotes the invasion of oesophageal squamous cell carcinoma via PI3K activation
Q40373122Laminin-5 suppresses chondrogenic differentiation of murine teratocarcinoma cell line ATDC5.
Q42497634Migratory marker expression in fibroblast foci of idiopathic pulmonary fibrosis
Q37142796N-Glycosylation of laminin-332 regulates its biological functions. A novel function of the bisecting GlcNAc
Q40181431Overexpression of laminin-5 gamma2 chain in clear cell carcinoma of the ovary
Q55351765Overexpression of α3, β3 and γ2 chains of laminin-332 is associated with poor prognosis in pancreatic ductal adenocarcinoma.
Q27304390Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration
Q31146677Regulation of biological activity and matrix assembly of laminin-5 by COOH-terminal, LG4-5 domain of alpha3 chain
Q34385160Role of galectins in re-epithelialization of wounds
Q39988218Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma
Q39415199Roles of Integrin α6β4 Glycosylation in Cancer
Q30581477Synthetic D-amino acid peptide inhibits tumor cell motility on laminin-5.
Q37340259The influence of substrate topography on the migration of corneal epithelial wound borders
Q24644946The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes
Q36800958Tumour microenvironment: laminin 332 in squamous-cell carcinoma
Q47298385Upregulated LAMB3 increases proliferation and metastasis in thyroid cancer

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