A neuroblastoma-selective suicide gene therapy approach using the tyrosine hydroxylase promoter.

scientific article published on 4 June 2004

A neuroblastoma-selective suicide gene therapy approach using the tyrosine hydroxylase promoter. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1010378189
P356DOI10.1203/01.PDR.0000132666.23103.EF
P698PubMed publication ID15181182

P50authorSabine SteffensQ63357516
Nikolai G. RainovQ70270544
P2093author name stringUte Fischer
Christof M Kramm
Christiane Lex
Susanne Frank
Anke Sandquist
P2860cites workCharacterization of rat and human tyrosine hydroxylase genes: functional expression of both promoters in neuronal and non-neuronal cell typesQ28283957
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
Catecholamine Metabolism in Neuroblastoma 1 2Q33713017
Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trialQ33905053
Prodrug activation enzymes in cancer gene therapyQ33968115
Gene expression from transcriptionally disabled retroviral vectorsQ34332994
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cellsQ35604467
Human dopamine beta-hydroxylase gene: two mRNA types having different 3'-terminal regions are produced through alternative polyadenylationQ36417592
Expression of human adenosine deaminase in murine hematopoietic cellsQ36849892
The biochemistry and mechanism of action of acyclovirQ40137953
Inhibition of human immunodeficiency virus type 1 by Tat/Rev-regulated expression of cytosine deaminase, interferon alpha2, or diphtheria toxin compared with inhibition by transdominant Rev.Q40972891
Screening for neuroblastoma: a review of the evidenceQ41098805
Inducible retroviral vectors regulated by lac repressor in mammalian cellsQ41145453
Gene transfer into mammalian central nervous system using herpes virus vectors: extended expression of bacterial lacZ in neurons using the neuron-specific enolase promoterQ41601982
Sequences in the proximal 5' flanking region of the rat neuron-specific enolase (NSE) gene are sufficient for cell type-specific reporter gene expressionQ42435600
In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain TumorsQ42818740
Differential cytotoxicity and bystander effect of the rabbit cytochrome P450 4B1 enzyme gene by two different prodrugs: implications for pharmacogene therapyQ45714279
A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.Q45739549
Enhanced green fluorescent protein fusion proteins of herpes simplex virus type 1 thymidine kinase and cytochrome P450 4B1: applications for prodrug-activating gene therapyQ45742183
Tumor cell-specific transgene expression prevents liver toxicity of the adeno-HSVtk/GCV approachQ45856053
Generation of a high titre retroviral vector for endothelial cell-specific gene expression in vivoQ45865684
Transgenic mice expressing beta-galactosidase in mature neurons under neuron-specific enolase promoter controlQ46168479
Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cellsQ48587406
Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.Q54635100
High gradient magnetic cell separation with MACSQ57339991
Synergy between 5′ and 3′ flanking regions of the human tyrosine hydroxylase gene ensures specific, high-level expression in neuroblastoma cellsQ57734314
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectsuicideQ10737
gene therapyQ213901
P304page(s)268-277
P577publication date2004-06-04
P1433published inPediatric ResearchQ7159215
P1476titleA neuroblastoma-selective suicide gene therapy approach using the tyrosine hydroxylase promoter
P478volume56

Reverse relations

cites work (P2860)
Q40559074Expression mediated by three partial sequences of the human tyrosine hydroxylase promoter in vivo
Q36534930Frontiers in Suicide Gene Therapy of Cancer
Q38808728Gene therapy as a potential tool for treating neuroblastoma-a focused review
Q33691870INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumors
Q39109782Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells

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