| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M313859200 |
| P698 | PubMed publication ID | 15078891 |
| P50 | author | Emma Creagh | Q43114705 |
| Seamus J. Martin | Q43266198 | ||
| Brona M Murphy | Q58811046 | ||
| P2093 | author name string | Patrick J Duriez | |
| Colin S Duckett | |||
| P2860 | cites work | Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner | Q22008727 |
| TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2 | Q24292505 | ||
| X-linked IAP is a direct inhibitor of cell-death proteases | Q24318710 | ||
| The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases | Q24532851 | ||
| Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c | Q24533921 | ||
| Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2 | Q24534641 | ||
| Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death | Q24630370 | ||
| The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites | Q24673550 | ||
| Structural and biochemical basis of apoptotic activation by Smac/DIABLO | Q27626899 | ||
| Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition | Q28115131 | ||
| Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli | Q28116145 | ||
| Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins | Q28117928 | ||
| The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7 | Q28138892 | ||
| The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases | Q28139237 | ||
| Mammalian caspases: structure, activation, substrates, and functions during apoptosis | Q28139429 | ||
| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis | Q28204205 | ||
| IAP family proteins--suppressors of apoptosis | Q28297514 | ||
| Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition | Q29035696 | ||
| Characterization of XIAP-deficient mice | Q33559119 | ||
| Control of programmed cell death by the baculovirus genes p35 and iap. | Q36662781 | ||
| A mutational analysis of the baculovirus inhibitor of apoptosis Op-IAP. | Q38330501 | ||
| Genetic control of programmed cell death in Drosophila | Q38468332 | ||
| Requirement of Both the Second and Third BIR Domains for the Relief of X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Caspase Inhibition by Smac | Q39389950 | ||
| Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark | Q39647181 | ||
| Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function | Q40387062 | ||
| Protease activation during apoptosis: death by a thousand cuts? | Q40459802 | ||
| Smac3, a Novel Smac/DIABLO Splicing Variant, Attenuates the Stability and Apoptosis-inhibiting Activity of X-linked Inhibitor of Apoptosis Protein | Q40629425 | ||
| Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein | Q40647783 | ||
| Agrin-induced phosphorylation of the acetylcholine receptor regulates cytoskeletal anchoring and clustering | Q40815262 | ||
| Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region | Q40941506 | ||
| The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. | Q41689719 | ||
| Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases | Q42657216 | ||
| Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis. | Q43509147 | ||
| Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro | Q44066914 | ||
| Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death | Q46725238 | ||
| Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms | Q46902175 | ||
| Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1. | Q47070254 | ||
| The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis | Q47071463 | ||
| Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. | Q47072202 | ||
| Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis | Q48303855 | ||
| P433 | issue | 26 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 26906-26914 | |
| P577 | publication date | 2004-04-12 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins | |
| P478 | volume | 279 |
| Q24321222 | ARTS and Siah collaborate in a pathway for XIAP degradation |
| Q45862336 | Adenoviral expression of XIAP antisense RNA induces apoptosis in glioma cells and suppresses the growth of xenografts in nude mice |
| Q39653516 | Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis |
| Q41536623 | Cellular inhibitor of apoptosis 1 (cIAP-1) degradation by caspase 8 during TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis |
| Q42009519 | Controlling TRAIL-mediated caspase-3 activation. |
| Q39099740 | Degradation of cIAPs contributes to hepatocyte lipoapoptosis |
| Q34132152 | Determination of cell survival by RING-mediated regulation of inhibitor of apoptosis (IAP) protein abundance |
| Q37371359 | Differential regulation of Smac/DIABLO and Hsp-70 during brain maturation |
| Q42275527 | Differential response of head and neck cancer cell lines to TRAIL or Smac mimetics is associated with the cellular levels and activity of caspase-8 and caspase-10 |
| Q37698911 | Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells |
| Q40122308 | Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease. |
| Q33395707 | Effects of endotoxin on liver Smac apoptosis channel |
| Q89696542 | Future Therapeutic Directions for Smac-Mimetics |
| Q51010941 | High expression of anti-apoptotic genes in grade I and II meningiomas. |
| Q24670396 | Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family |
| Q24300734 | IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis |
| Q37302745 | IAP-targeted therapies for cancer |
| Q37987881 | IAPS and ubiquitylation |
| Q36085601 | IAPs, RINGs and ubiquitylation |
| Q46645031 | IAPs--the ubiquitin connection |
| Q34018441 | Induction of caspase-3-like activity in rice following release of cytochrome-f from the chloroplast and subsequent interaction with the ubiquitin-proteasome system |
| Q40386827 | Inhibition of clonogenic tumor growth: a novel function of Smac contributing to its antitumor activity |
| Q37134050 | Inhibitor of apoptosis proteins and apoptosis |
| Q24338158 | Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway |
| Q36804432 | Multifaceted targeting in cancer: the recent cell death players meet the usual oncogene suspects |
| Q34547602 | Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1. |
| Q42632400 | Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B. |
| Q80337028 | Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria |
| Q29871514 | SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis |
| Q41847136 | SmacN7 enhances the sensitivity of pancreatic cancer cells to tumor necrosis factor-related apoptosis-inducing ligand or gemcitabine |
| Q35069365 | Splice variants of mIAP1 have an enhanced ability to inhibit apoptosis |
| Q38742944 | Targeting Hsp70: A possible therapy for cancer |
| Q90395021 | Targeting XIAP for Promoting Cancer Cell Death-The Story of ARTS and SMAC |
| Q28386906 | The ubiquitin-proteasome system in spongiform degenerative disorders |
| Q43975695 | XAF1 mRNA expression improves progression-free and overall survival for patients with advanced bladder cancer treated with neoadjuvant chemotherapy |
| Q37546803 | XIAP as a ubiquitin ligase in cellular signaling |
Search more.