| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M313964200 |
| P698 | PubMed publication ID | 15037631 |
| P2093 | author name string | Jiahuai Han | |
| Richard M Schultz | |||
| Guan Chen | |||
| Senji Shirasawa | |||
| Jun Tang | |||
| Takehiko Sasazuki | |||
| Xiaomei Qi | |||
| Rocky Pramanik | |||
| P2860 | cites work | Estrogen receptor inhibits c-Jun-dependent stress-induced cell death by binding and modifying c-Jun activity in human breast cancer cells | Q40613355 |
| Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells | Q40664009 | ||
| Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation | Q40722624 | ||
| Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic | Q40745426 | ||
| PPAR? agonists inhibit cell growth and suppress the expression of cyclin D1 and EGF-like growth factors in ras-transformed rat intestinal epithelial cells | Q40763140 | ||
| The p38 pathway provides negative feedback for Ras proliferative signaling | Q40856194 | ||
| Targeted disruption of the K-ras oncogene in an invasive colon cancer cell line down-regulates urokinase receptor expression and plasminogen-dependent proteolysis | Q40931728 | ||
| Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor | Q41546932 | ||
| Detection of high incidence of K-ras oncogenes during human colon tumorigenesis | Q41822747 | ||
| p120 GAP modulates Ras activation of Jun kinases and transformation | Q42804641 | ||
| Altered growth of human colon cancer cell lines disrupted at activated Ki-ras | Q42810367 | ||
| Selective activation of Ha-ras(val12) oncogene increases susceptibilityof NIH/3T3 cells to TNF-alpha. | Q42816464 | ||
| Role of mitogen-activated protein kinases and c-Jun/AP-1 trans-activating activity in the regulation of protease mRNAs and the malignant phenotype in NIH 3T3 fibroblasts. | Q42823190 | ||
| Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73 | Q42825163 | ||
| Oncogenic transformation potentiates apoptosis, S-phase arrest and stress-kinase activation by etoposide | Q42832664 | ||
| Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. | Q42859934 | ||
| Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery | Q43559980 | ||
| Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid | Q43891144 | ||
| The p38 and JNK pathways cooperate to trans-activate vitamin D receptor via c-Jun/AP-1 and sensitize human breast cancer cells to vitamin D(3)-induced growth inhibition | Q43976249 | ||
| The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair | Q44381511 | ||
| Cross-talk between JNK/SAPK and ERK/MAPK pathways: sustained activation of JNK blocks ERK activation by mitogenic factors | Q44435276 | ||
| Stable suppression of tumorigenicity by virus-mediated RNA interference | Q45730805 | ||
| Increasing Complexity of the Ras Signaling Pathway | Q47762067 | ||
| Increasing complexity of Ras signaling | Q53429989 | ||
| Prevalence of ras gene mutations in human colorectal cancers | Q59088716 | ||
| Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest | Q22254227 | ||
| Characterization of the structure and function of a novel MAP kinase kinase (MKK6) | Q24336966 | ||
| JDP2, a repressor of AP-1, recruits a histone deacetylase 3 complex to inhibit the retinoic acid-induced differentiation of F9 cells | Q24537570 | ||
| Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions | Q24646252 | ||
| MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway | Q24650627 | ||
| A system for stable expression of short interfering RNAs in mammalian cells | Q27860875 | ||
| A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf | Q28263195 | ||
| Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine | Q28287650 | ||
| Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo | Q28368373 | ||
| Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning | Q28508915 | ||
| Selective Activation of p38 Mitogen-activated Protein (MAP) Kinase Isoforms by the MAP Kinase Kinases MKK3 and MKK6 | Q28678886 | ||
| Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis | Q29547567 | ||
| Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase | Q29616448 | ||
| Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells | Q29618480 | ||
| The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation | Q29620219 | ||
| The regulation of AP-1 activity by mitogen-activated protein kinases | Q29620431 | ||
| Essential role for oncogenic Ras in tumour maintenance | Q30150290 | ||
| The p38 signal transduction pathway: activation and function | Q33838955 | ||
| Elucidating cell signaling mechanisms using antisense technology | Q33877254 | ||
| Human-tumor-derived cell lines contain common and different transforming genes | Q34245850 | ||
| The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway | Q34453600 | ||
| Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induces Expression of the Helix-Loop-Helix Protein Id-1 in Human Endothelial Cells | Q34976840 | ||
| Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases | Q35548571 | ||
| Transcriptional repression of the interleukin-2 gene by vitamin D3: direct inhibition of NFATp/AP-1 complex formation by a nuclear hormone receptor | Q36555534 | ||
| Cellular transformation and malignancy induced by ras require c-jun | Q36561672 | ||
| Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia | Q36576317 | ||
| Cloning and characterization of the mouse vitamin D receptor promoter | Q36583162 | ||
| Reduction of Intrafollicular Apoptosis in Chemotherapy-Induced Alopecia by Topical Calcitriol-Analogs | Q36898791 | ||
| Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress | Q39528509 | ||
| Dissection of Ras-dependent signaling pathways controlling aggressive tumor growth of human fibrosarcoma cells: evidence for a potential novel pathway | Q39540239 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | vitamin D | Q175621 |
| colon cancer | Q18555025 | ||
| P1104 | number of pages | 7 | |
| P304 | page(s) | 22138-22144 | |
| P577 | publication date | 2004-03-22 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | p38 MAPK activation selectively induces cell death in K-ras-mutated human colon cancer cells through regulation of vitamin D receptor | |
| P478 | volume | 279 |
| Q35537834 | A synthetic lethal screen identifies the Vitamin D receptor as a novel gemcitabine sensitizer in pancreatic cancer cells |
| Q92967577 | Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial |
| Q53368213 | Epibrassinolide alters PI3K/MAPK signaling axis via activating Foxo3a-induced mitochondria-mediated apoptosis in colon cancer cells |
| Q40430785 | Essential role of p38gamma in K-Ras transformation independent of phosphorylation |
| Q33654192 | Exon-level transcriptome profiling in murine breast cancer reveals splicing changes specific to tumors with different metastatic abilities |
| Q36463216 | Genetic and epigenetic biomarkers in cancer : improving diagnosis, risk assessment, and disease stratification |
| Q38981572 | Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer |
| Q40169850 | Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells |
| Q41884394 | Loss of integrin alpha1beta1 ameliorates Kras-induced lung cancer |
| Q39941818 | Lovastatin induces apoptosis of k-ras-transformed thyroid cells via inhibition of ras farnesylation and by modulating redox state |
| Q35892864 | Mechanisms of regulation of oligodendrocyte development by p38 mitogen-activated protein kinase |
| Q53682760 | Multi-kinase inhibitor with anti-p38γ activity in cutaneous T cell lymphoma |
| Q24606638 | PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction |
| Q90239945 | Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance) |
| Q37157816 | Reactive oxygen species: a double-edged sword in oncogenesis |
| Q27695708 | Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formation |
| Q39798367 | Sensitization to apoptosis underlies KrasD12-dependent oncolysis of murine C26 colorectal carcinoma cells by reovirus T3D. |
| Q40205386 | Stress-induced c-Jun-dependent Vitamin D receptor (VDR) activation dissects the non-classical VDR pathway from the classical VDR activity |
| Q37564565 | TES inhibits colorectal cancer progression through activation of p38. |
| Q89658448 | Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity |
| Q47817412 | The K-Ras effector p38γ MAPK confers intrinsic resistance to tyrosine kinase inhibitors by stimulating EGFR transcription and EGFR dephosphorylation |
| Q26767360 | The Non-Genomic Actions of Vitamin D |
| Q36955934 | The Vitamin D Receptor, Inflammatory Bowel Diseases, and Colon Cancer |
| Q36592365 | The p38 MAPK stress pathway as a tumor suppressor or more? |
| Q35195234 | The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease |
| Q36855028 | Thymosin beta 4 mediates oligodendrocyte differentiation by upregulating p38 MAPK |
| Q42807800 | Tumorigenesis of K-ras mutation in human endometrial carcinoma via upregulation of estrogen receptor. |
| Q37400664 | Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer. |
| Q34033348 | Vitamin D receptor negatively regulates bacterial-stimulated NF-kappaB activity in intestine |
| Q35803006 | p38 mitogen-activated protein kinase inhibits USP22 transcription in HeLa cells |
| Q39380148 | p38 mitogen‐activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients |
| Q34667875 | p38alpha antagonizes p38gamma activity through c-Jun-dependent ubiquitin-proteasome pathways in regulating Ras transformation and stress response |
| Q33832433 | p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9. |
| Q36326219 | p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion |
| Q34008781 | p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance. |
| Q48083372 | p38γ MAPK is required for inflammation-associated colon tumorigenesis |
| Q36201947 | p38γ Mitogen-activated Protein Kinase Signals through Phosphorylating Its Phosphatase PTPH1 in Regulating Ras Protein Oncogenesis and Stress Response |
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