Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro

scientific article published on 21 November 2003

Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M307759200
P8608Fatcat IDrelease_mstn3ue4fze7toqz3bri762yce
P698PubMed publication ID14634022

P2093author name stringCsaba Szabó
Sunali Goonesekera
Andrew L Salzman
Kanneganti G K Murthy
Amitabha Deb
P2860cites workStructure of the bacterial flagellar protofilament and implications for a switch for supercoilingQ27630815
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cellsQ27860599
Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cellsQ28179206
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5Q28185796
Activation of interleukin-1 receptor-associated kinase by gram-negative flagellinQ28201436
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expressionQ28211358
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory responseQ28345391
Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells.Q30305779
Two nonadjacent regions in enteroaggregative Escherichia coli flagellin are required for activation of toll-like receptor 5.Q30309845
High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activationQ33591155
Flagellin stimulation of intestinal epithelial cells triggers CCL20-mediated migration of dendritic cells.Q33949995
Comparison of inflammation, organ damage, and oxidant stress induced by Salmonella enterica serovar Muenchen flagellin and serovar Enteritidis lipopolysaccharideQ34116277
Regulation of flagellar assemblyQ34588853
Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cellsQ34853145
Structural study of binding of flagellin by Toll-like receptor 5.Q39787971
Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexesQ40641430
Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from toll-like receptor 5.Q40738252
The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cellsQ40753377
Salmonella flagellin-dependent proinflammatory responses are localized to the conserved amino and carboxyl regions of the proteinQ40764434
Identification of a Sequence in Human Toll-like Receptor 5 Required for the Binding of Gram-negative FlagellinQ50104203
Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsisQ50105381
Salmonella enteritidis FliC (flagella filament protein) induces human beta-defensin-2 mRNA production by Caco-2 cellsQ50115124
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunctionQ50117610
P433issue7
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)5667-5675
P577publication date2003-11-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro
P478volume279