In-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome

scientific article published on March 2004

In-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.186.6.1769-1784.2004
P932PMC publication ID355958
P698PubMed publication ID14996808

P50authorJens O KrömerQ38544892
Christoph WittmannQ38644727
Elmar HeinzleQ88163007
P2093author name stringOliver Sorgenfrei
Kai Klopprogge
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Quantitative determination of metabolic fluxes during coutilization of two carbon sources: comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucoseQ39499679
Functions of the membrane-associated and cytoplasmic malate dehydrogenases in the citric acid cycle of Corynebacterium glutamicum.Q39501453
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Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose.Q40467948
NADH dehydrogenase of Corynebacterium glutamicum. Purification of an NADH dehydrogenase II homolog able to oxidize NADPH.Q43814169
A novel methodology employing Corynebacterium glutamicum genome information to generate a new L-lysine-producing mutantQ43903994
Transcriptome analysis of acetate metabolism in Corynebacterium glutamicum using a newly developed metabolic arrayQ44089842
Response of the central metabolism of Corynebacterium glutamicum to different flux burdensQ44365124
Disparity between changes in mRNA abundance and enzyme activity in Corynebacterium glutamicum: implications for DNA microarray analysisQ44377321
Metabolic flux analysis of pykF gene knockout Escherichia coli based on 13C-labeling experiments together with measurements of enzyme activities and intracellular metabolite concentrationsQ44475462
Combined use of proteomic analysis and enzyme activity assays for metabolic pathway analysis of glycerol fermentation by Klebsiella pneumoniaeQ44492291
Impact of the cold shock phenomenon on quantification of intracellular metabolites in bacteriaQ44807070
Bidirectional reaction steps in metabolic networks: II. Flux estimation and statistical analysis.Q51648132
Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing.Q52312607
Flux partitioning in the split pathway of lysine synthesis in Corynebacterium glutamicum. Quantification by 13C- and 1H-NMR spectroscopy.Q52396444
In vivo analysis of intracellular amino acid labelings by GC/MSQ57989266
Mass spectrometry for metabolic flux analysisQ57989442
Mapping and identification ofCorynebacterium glutamicum proteins by two-dimensional gel electrophoresis and microsequencingQ58007101
Combined transcriptome and proteome analysis ofEscherichia coli during high cell density cultureQ61447631
Carrier-mediated glutamate secretion by Corynebacterium glutamicum under biotin limitationQ67522597
Two-dimensional electrophoretic analysis of Corynebacterium glutamicum membrane fraction and surface proteinsQ73569646
Regulation of acetate metabolism in Corynebacterium glutamicum: transcriptional control of the isocitrate lyase and malate synthase genesQ73698326
Response to nitrogen starvation in Corynebacterium glutamicumQ73827985
Kinetic properties of the glucose-6-phosphate and 6-phosphogluconate dehydrogenases from Corynebacterium glutamicum and their application for predicting pentose phosphate pathway flux in vivoQ73883659
GC-MS analysis of amino acids rapidly provides rich information for isotopomer balancingQ74138546
A universal framework for 13C metabolic flux analysisQ74227987
Carbon-flux distribution in the central metabolic pathways of Corynebacterium glutamicum during growth on fructoseQ74750963
P433issue6
P921main subjecttranscriptomeQ252857
Corynebacterium glutamicumQ292314
P304page(s)1769-1784
P577publication date2004-03-01
P1433published inJournal of BacteriologyQ478419
P1476titleIn-depth profiling of lysine-producing Corynebacterium glutamicum by combined analysis of the transcriptome, metabolome, and fluxome
P478volume186

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