D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4.

scientific article published on September 2003

D2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI0345539
P698PubMed publication ID12974638

P2093author name stringBrian F O'Dowd
Susan R George
Tuan Nguyen
Samuel P Lee
Ryan D Rajaram
P2860cites workChimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificityQ34681325
P433issue37
P407language of work or nameEnglishQ1860
P921main subjecttransmembrane proteinQ424204
P304page(s)11023-11031
P577publication date2003-09-01
P1433published inBiochemistryQ764876
P1476titleD2 dopamine receptor homodimerization is mediated by multiple sites of interaction, including an intermolecular interaction involving transmembrane domain 4.
P478volume42

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cites work (P2860)
Q36983708A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization
Q45951012A highly conserved tryptophan residue in the fourth transmembrane domain of the A adenosine receptor is essential for ligand binding but not receptor homodimerization.
Q34356107A peptide targeting an interaction interface disrupts the dopamine D1-D2 receptor heteromer to block signaling and function in vitro and in vivo: effective selective antagonism
Q37154244Acute and chronic dopamine receptor stimulation modulates AMPA receptor trafficking in nucleus accumbens neurons cocultured with prefrontal cortex neurons
Q36822598Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif
Q35925892Chemotaxis receptors and signaling
Q34142522Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation
Q37701167Crustacean dopamine receptors: localization and G protein coupling in the stomatogastric ganglion
Q40415960Cysteine residues are critical for chemokine receptor CXCR2 functional properties
Q64076594Distinct Dopamine D₂ Receptor Antagonists Differentially Impact D₂ Receptor Oligomerization
Q34075685Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease
Q33788002Dominant negative effects of human follicle-stimulating hormone receptor expression-deficient mutants on wild-type receptor cell surface expression. Rescue of oligomerization-dependent defective receptor expression by using cognate decoys
Q46675901Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion
Q33983589Dopamine receptor expression and distribution dynamically change in the rat nucleus accumbens after withdrawal from cocaine self-administration
Q46663693Dopamine receptor oligomerization visualized in living cells
Q36191579Entropy and oligomerization in GPCRs
Q36211455Existence and theoretical aspects of homomeric and heteromeric dopamine receptor complexes and their relevance for neurological diseases
Q37367709Fluorescent and bioluminescent protein-fragment complementation assays in the study of G protein-coupled receptor oligomerization and signaling
Q34345068Fluorescent protein complementation assays: new tools to study G protein-coupled receptor oligomerization and GPCR-mediated signaling.
Q35842023Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surface
Q82029286Functional neurochemistry of the basal ganglia
Q39839857Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones
Q37421818G protein-coupled receptor hetero-dimerization: contribution to pharmacology and function
Q57781319G protein-coupled receptor oligomerization for what?
Q35011230GRIP: a server for predicting interfaces for GPCR oligomerization
Q33306518Genes encoding putative biogenic amine receptors in the parasitic nematode Brugia malayi
Q92642583Heterodimerization of Mu Opioid Receptor Protomer with Dopamine D2 Receptor Modulates Agonist-Induced Internalization of Mu Opioid Receptor
Q37379456Heteromeric dopamine receptor signaling complexes: emerging neurobiology and disease relevance
Q36191583How proteins come together in the plasma membrane and function in macromolecular assemblies: focus on receptor mosaics.
Q40477812Identification of the cytoplasmic domains of CXCR4 involved in Jak2 and STAT3 phosphorylation.
Q34442688Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor
Q33767121Increasingly accurate dynamic molecular models of G-protein coupled receptor oligomers: Panacea or Pandora's box for novel drug discovery?
Q50993982Inhibition of melanocortin-4 receptor dimerization by substitutions in intracellular loop 2
Q40367280Inhibition of serotonin 5-hydroxytryptamine2c receptor function through heterodimerization: receptor dimers bind two molecules of ligand and one G-protein
Q43950868Integrin triplets of marine sponges in human D2 receptor heteromers
Q41767833Lessons from free energy simulations of delta-opioid receptor homodimers involving the fourth transmembrane helix
Q34160481Making structural sense of dimerization interfaces of delta opioid receptor homodimers
Q34548734Methods used to study the oligomeric structure of G-protein-coupled receptors
Q35749944Molecular basis for the chloride channel activity of cystic fibrosis transmembrane conductance regulator and the consequences of disease-causing mutations
Q37351126Mutations in G protein-coupled receptors that impact receptor trafficking and reproductive function.
Q35546811Oligomerization of G protein-coupled receptors: past, present, and future
Q34232914Oligomerization of G-protein-coupled receptors: lessons from the yeast Saccharomyces cerevisiae
Q30991104Organization of rhodopsin molecules in native membranes of rod cells--an old theoretical model compared to new experimental data
Q46692544Physicochemical modulation of agonist-induced [35s]GTPgammaS binding: implications for coexistence of multiple functional conformations of dopamine D1-like receptors
Q38946091Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling
Q39607436Receptor specific crosstalk and modulation of signaling upon heterodimerization between β1-adrenergic receptor and somatostatin receptor-5
Q28567232Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization
Q33580523Single and binge methamphetamine administrations have different effects on the levels of dopamine D2 autoreceptor and dopamine transporter in rat striatum
Q40138581Specificity of olfactory receptor interactions with other G protein-coupled receptors
Q38292961Structure and function of G protein-coupled receptor oligomers: implications for drug discovery
Q39895376Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization
Q38887428The Follitropin Receptor: Matching Structure and Function
Q34432609The G protein-coupled receptor rhodopsin in the native membrane
Q36310854The G protein-coupled receptors: pharmacogenetics and disease
Q44982172The hydrodynamic properties of dark- and light-activated states of n-dodecyl beta-D-maltoside-solubilized bovine rhodopsin support the dimeric structure of both conformations
Q36191590The specificity and molecular basis of alpha1-adrenoceptor and CXCR chemokine receptor dimerization
Q35855537Trafficking of the follitropin receptor
Q37967933Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors

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