The myristylation signal of p60v-src functionally complements the N-terminal fps-specific region of P130gag-fps

scientific article published on May 1989

The myristylation signal of p60v-src functionally complements the N-terminal fps-specific region of P130gag-fps is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.9.5.2214
P932PMC publication ID363016
P698PubMed publication ID2747647

P2093author name stringPawson T
Brooks-Wilson AR
Ball E
P2860cites workReplacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucoseQ24299251
The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membraneQ28575831
A lysine in the ATP-binding site of P130gag-fps is essential for protein-tyrosine kinase activity.Q33879284
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylationQ34166097
A conserved domain regulates interactions of the v-fps protein-tyrosine kinase with the host cellQ34378948
Intracellular distributions of mechanochemical proteins in cultured fibroblastsQ35051050
Organization of pp60src and selected cytoskeletal proteins within adhesion plaques and junctions of Rous sarcoma virus-transformed rat cellsQ36204906
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblastsQ36272657
Immunofluorescent localization of the transforming protein of Rous sarcoma virus with antibodies against a synthetic src peptideQ36310517
Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene productQ36394145
Association of pp60src and src protein kinase activity with the plasma membrane of nonpermissive and permissive avian sarcoma virus-infected cellsQ36508814
The human c-fps/fes gene product expressed ectopically in rat fibroblasts is nontransforming and has restrained protein-tyrosine kinase activityQ36782634
The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinantQ36790275
The six amino-terminal amino acids of p60src are sufficient to cause myristylation of p21v-rasQ36845819
The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activityQ36862547
Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related proteinQ36894127
Cellular localization of the transforming protein of wild-type and temperature-sensitive Fujinami sarcoma virusQ36895816
Cellular localization of c-fps gene product NCP98.Q36896776
Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homologQ36903643
Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma virusesQ36909345
A fps gene without gag gene sequences transforms cells in culture and induces tumors in chickensQ36910334
Nucleotide sequence of v-fps in the PRCII strain of avian sarcoma virusQ36914158
Monoclonal antibodies to the transforming protein of Fujinami avian sarcoma virus discriminate between different fps-encoded proteinsQ36916263
Cytoplasmic localization of the transforming protein of Fujinami sarcoma virus: salt-sensitive association with subcellular componentsQ36930513
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformationQ36947661
Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformationQ37523303
Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells.Q37684441
Anatomy of fos proteinsQ39607792
Construction and biological analysis of deletion mutants of Fujinami sarcoma virus: 5'-fps sequence has a role in the transforming activityQ40136609
Correspondence between immunological and functional domains in the transforming protein of Fujinami sarcoma virusQ40136699
Immunofluorescence on avian sarcoma virus-transformed cells: Localization of the src gene productQ40209262
Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistryQ40273384
An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteinsQ41488933
Normal rat cell lines deficient in nuclear thymidine kinaseQ42801798
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-srcQ44049774
Evidence that the src gene product of rous sarcoma virus is membrane associatedQ44731356
Identification of functional regions in the transforming protein of Fujinami sarcoma virus by in-phase insertion mutagenesisQ45796587
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipidQ45798971
The pathogenicity and defectiveness of PRCII: a new type of avian sarcoma virusQ45805547
Activation of the transformation potential of the cellular fps gene.Q53542962
Transforming proteins of fujinami and PRCII avian sarcoma viruses have different subcellular locationsQ70215867
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)2214-2219
P577publication date1989-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleThe myristylation signal of p60v-src functionally complements the N-terminal fps-specific region of P130gag-fps
P478volume9