PEGylation of microspheres generates a heterogeneous population of particles with differential surface characteristics and biological performance.

scientific article published on December 2002

PEGylation of microspheres generates a heterogeneous population of particles with differential surface characteristics and biological performance. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-5793(02)03710-9
P698PubMed publication ID12482589

P50authorSeyed Moein MoghimiQ38800257
Alan C. HunterQ73023913
P2093author name stringJ K Gbadamosi
P2860cites workInfluence of surface properties at biodegradable microsphere surfaces: effects on plasma protein adsorption and phagocytosisQ32078607
Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules.Q40778195
Recognition and clearance of methoxypoly(ethyleneglycol)2000-grafted liposomes by macrophages with enhanced phagocytic capacity. Implications in experimental and clinical oncologyQ43643349
Chemical camouflage of nanospheres with a poorly reactive surface: towards development of stealth and target-specific nanocarriersQ44026880
Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophagesQ44945836
In vitro cell interaction and in vivo biodistribution of poly(lactide-co-glycolide) nanospheres surface modified by poloxamer and poloxamine copolymersQ58622686
Polystyrene-poly (ethylene glycol) (PS-PEG2000) particles as model systems for site specific drug delivery. 2. The effect of PEG surface density on the in vitro cell interaction and in vivo biodistributionQ58622732
A colorimetric assay for estimation of polyethylene glycol and polyethylene glycolated protein using ammonium ferrothiocyanateQ71138767
Prolonging the circulation time and modifying the body distribution of intravenously injected polystyrene nanospheres by prior intravenous administration of poloxamine-908. A 'hepatic-blockade' event or manipulation of nanosphere surface in vivo?Q73626520
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmicrosphereQ1759020
P304page(s)338-344
P577publication date2002-12-01
P1433published inFEBS LettersQ1388051
P1476titlePEGylation of microspheres generates a heterogeneous population of particles with differential surface characteristics and biological performance
P478volume532

Reverse relations

cites work (P2860)
Q47295354Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization.
Q34709440Cell-mediated drug delivery.
Q35878143Complement activation and cell uptake responses toward polymer-functionalized protein nanocapsules
Q42912187Complement activation by PEGylated single-walled carbon nanotubes is independent of C1q and alternative pathway turnover
Q49166049Complement activation turnover on surfaces of nanoparticles.
Q42723786Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
Q26345204Current understanding of interactions between nanoparticles and the immune system
Q38089879Designing PEGylated therapeutic molecules: advantages in ADMET properties
Q33985140Drug transport to brain with targeted nanoparticles
Q37360660Effect of the poly(ethylene glycol) (PEG) density on the access and uptake of particles by antigen-presenting cells (APCs) after subcutaneous administration
Q37550733Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats
Q37445335Heterogeneity in nanoparticles influences biodistribution and targeting
Q33525333In vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles
Q30366990Lipid-Based Drug Delivery Systems in Cancer Therapy: What Is Available and What Is Yet to Come.
Q37712288Loading of hydrophobic materials into polymer particles: implications for fluorescent nanosensors and drug delivery
Q33631069Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins.
Q44394289Modulation of lymphatic distribution of subcutaneously injected poloxamer 407-coated nanospheres: the effect of the ethylene oxide chain configuration
Q37890639Nanomedicine: novel approaches in human and veterinary therapeutics
Q37015442Nanotechnology: a focus on nanoparticles as a drug delivery system
Q39577084Oleanolic acid liposomes with polyethylene glycol modification: promising antitumor drug delivery
Q38767557PEGylated Cationic Serum Albumin for Boosting Retroviral Gene Transfer
Q36604526Pharmacokinetic consequences of pegylation
Q38047267Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking
Q28384922Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers
Q34312572Poly(ethylene oxide)-modified poly(beta-amino ester) nanoparticles as a pH-sensitive system for tumor-targeted delivery of hydrophobic drugs: part 2. In vivo distribution and tumor localization studies
Q35893655Preparation, characterization, and in vitro drug release behavior of glutathione-sensitive long-circulation micelles based on polyethylene glycol prodrug
Q28391811Rapid Hepatobiliary Excretion of Micelle-Encapsulated/Radiolabeled Upconverting Nanoparticles as an Integrated Form
Q31149542Real-time evidence of surface modification at polystyrene lattices by poloxamine 908 in the presence of serum: in vivo conversion of macrophage-prone nanoparticles to stealth entities by poloxamine 908.
Q38959097Recent trends in targeted therapy of cancer using graphene oxide-modified multifunctional nanomedicines
Q37883126Stabilization and functionalization of iron oxide nanoparticles for biomedical applications
Q27496024Stealth Properties to Improve Therapeutic Efficacy of Drug Nanocarriers
Q35559623Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties
Q37234835Surface Modification of Protein Nanocontainers and Their Self-Directing Character in Polymer Blends
Q37978315Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy
Q41829461Third generation gold nanoplatform optimized for radiation therapy
Q34704754Tissue distribution and pharmacokinetics of stable polyacrylamide nanoparticles following intravenous injection in the rat.