Polystyrene-poly (ethylene glycol) (PS-PEG2000) particles as model systems for site specific drug delivery. 2. The effect of PEG surface density on the in vitro cell interaction and in vivo biodistribution

scientific article published on 01 July 1994

Polystyrene-poly (ethylene glycol) (PS-PEG2000) particles as model systems for site specific drug delivery. 2. The effect of PEG surface density on the in vitro cell interaction and in vivo biodistribution is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1023/A:1018939521589
P698PubMed publication ID7937542

P50authorMartyn DaviesQ43122067
P2093author name stringS E Dunn
S S Davis
L Illum
A Brindley
P2860cites workSurface modification of nanoparticles by PEO/PPO block copolymers to minimize interactions with blood components and prolong blood circulation in ratsQ38568135
Liposomes for the sustained drug release in vivoQ41176853
Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivoQ42042312
Effect of molecular weight in amphipathic polyethyleneglycol on prolonging the circulation time of large unilamellar liposomesQ42100633
Serum opsonins and phagocytosis of saturated and unsaturated phospholipid liposomesQ44466173
Surface characteristics and the interaction of colloidal particles with mouse peritoneal macrophagesQ44962746
Influence of block copolymers on the adsorption of plasma proteins to microspheres.Q54247888
Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomesQ56386325
Sterie stabilization of microspheres with grafted polyethylene oxide reduces phagocytosis by rat Kupffer cells in vitroQ58622817
Direct suppression of phagocytosis by amphipathic polymeric surfactantsQ67562029
The effect of block co-polymers on the uptake of model polystyrene microspheres by Kupffer cells--in vitro and in vivo studiesQ67841480
Influence of surface hydrophilicity of liposomes on their interaction with plasma protein and clearance from the circulation: studies with poly(ethylene glycol)-coated vesiclesQ68205065
The polyoxyethylene/polyoxypropylene block co-polymer poloxamer-407 selectively redirects intravenously injected microspheres to sinusoidal endothelial cells of rabbit bone marrowQ68213213
Clinical application of antithrombogenic hydrogel with long poly(ethylene oxide) chainsQ68736631
Targeting of colloidal particles to the bone marrowQ68970018
Protein-resistant surfaces prepared by PEO-containing block copolymer surfactantsQ69600150
The organ distribution and circulation time of intravenously injected colloidal carriers sterically stabilized with a block copolymer--poloxamine 908Q69732153
Influence of the steric barrier activity of amphipathic poly(ethyleneglycol) and ganglioside GM1 on the circulation time of liposomes and on the target binding of immunoliposomes in vivoQ70213084
Molecular mechanism of the lipid vesicle longevity in vivoQ70608875
Release from alveolar macrophages of an inhibitor of phagocytosisQ71481316
Coating particles with a block co-polymer (poloxamine-908) suppresses opsonization but permits the activity of dysopsonins in the serumQ72552049
An investigation of the filtration capacity and the fate of large filtered sterically-stabilized microspheres in rat spleenQ72812326
P433issue7
P921main subjectdrug deliveryQ1392806
P304page(s)1016-1022
P577publication date1994-07-01
P1433published inPharmaceutical ResearchQ7180737
P1476titlePolystyrene-poly (ethylene glycol) (PS-PEG2000) particles as model systems for site specific drug delivery. 2. The effect of PEG surface density on the in vitro cell interaction and in vivo biodistribution
P478volume11

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cites work (P2860)
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